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| Pharmacogenomics: Delivering on the Promise |
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| Table of Contents Published: 2009/06 |
| Pharmacogenomics (PGx) is often considered the great new wave in medicine, promising better, safer, and more affordable healthcare. Yet its adoption and widespread use in the clinic is up against some tremendous challenges. ... |
| Approaches to Reducing Phase II Attrition |
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| Table of Contents Published: 2009/05 |
| Phase II is the critical development stage in which most clinical attrition occurs. This report focuses on approaches to improving R&D productivity in the pharmaceutical and biotechnology industries and considers: ... |
| Protease Inhibitors: Innovation Drives Drug Pipeline |
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| Table of Contents Published: 2009/02 |
| Proteases constitute one of the largest potential drug target enzyme families, with 647 human gene products incorporating protease sequences and mutated proteases having been identified. In addition, there are many more proteases found in viruses, bacteri ... |
| Stem Cells Come of Age Report Overview |
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| Table of Contents Published: 2008/11 |
| Stem cell science is on the precipice of becoming big business. These enigmatic cells lie at the heart of a fledgling technology with great clinical promise. Stem Cells Come of Age analyzes the current state of stem cell science and technology, and explor ... |
| GPCRs: Dawn of a New Era? |
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| Table of Contents Published: 2008/10 |
| Current advances in functional screening methodologies, medicinal chemistry, and structure-based drug design have generated large increases in the number and diversity of GPCR drug targets. ... |
| Cancer Biomarkers: Adoption Is Driving Growth |
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| Table of Contents Published: 2008/07 |
| Cancer Biomarkers: Adoption Is Driving Growth explores the various applications for cancer biomarkers across the healthcare spectrum by presenting the successful adoption of specific biomarkers. These applications include the identification of novel thera ... |
| Systems Biology: A Disruptive Technology |
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| Table of Contents Published: 2008/05 |
| This report focuses on the current and future applications of Systems Biology in drug discovery, specifically in pinpointing optimal individual targets, and combinations of targets, to overcome metabolic pathway redundancies, leading to efficacious and sa ... |
| Oncogenomics: The Future of Cancer Care |
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| Table of Contents Published: 2006/01 |
| Oncogenomics: The Future of Cancer Care analyzes the key advances and challenges associated with translating research efforts into successful, clinically meaningful therapeutic products. The emergence of oncogenomics promises a new era of cancer care. ... |
| GPCRs: Mining the Richest Vein in Drug Discovery |
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| Table of Contents Published: 2003/05 |
| This report describes the current state-of-the-art in both GPCR screening and downstream technology, as well as the various strategies being employed by firms in the field to advance their technologies and products. Also included are capsules of key compe ... |
| Proteomics Survey 2003 |
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| Table of Contents Published: 2003/04 |
| The report examines all major aspects of proteomics, including protein separation, ultrafiltration, 1D and 2D gel electrophoresis, liquid chromatography, capillary electrophoresis, mass spectrometry, protein informatics, protein arrays, protein quantifica ... |
| Proteomics Survey Report 2003 |
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| Table of Contents Published: 2003/02 |
| The report examines all major aspects of proteomics, including protein separation, ultrafiltration, 1D and 2D gel electrophoresis, liquid chromatography, capillary electrophoresis, mass spectrometry, protein informatics, protein arrays, protein quantifica ... |
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