Table of Contents
Chapter- 1: INTRODUCTION -- Complimentary 4
- STUDY GOALS AND OBJECTIVES 1
- REASONS FOR DOING THE STUDY 1
- SCOPE OF REPORT 1
- INTENDED AUDIENCE 2
- METHODOLOGY AND INFORMATION SOURCES 2
- ANALYST CREDENTIALS 3
- RELATED BCC REPORTS 3
- BCC ONLINE SERVICES 3
- DISCLAIMER 4
Chapter-2: SUMMARY 2NERAL DESCRIPTION 7
- DEFINITIONS 7
- Antibody 8
- Antigen 8
- Apoptosis 8
- Biomarker 8
- Biospecimen 8
- Cell 9
- TABLE 1 CHARACTERISTICS OF PROKARYOTIC AND EUKARYOTIC CELLS 9
- TABLE 2 CHARACTERISTICS OF PLANT AND ANIMAL CELLS 9
- TABLE 2 (CONTINUED) 10
- Cell-Based Assay 10
- Epitope 10
- Flow Cytometer 10
- FIGURE 1 MAIN COMPONENTS OF A FLOW CYTOMETER 11
- Fluorescence Activated Cell Sorting 12
- High-Content Screening 12
- Hybridoma 12
- Immunohistochemistry 12
- In vitro Culture 13
- Isotype 13
- Laser Microdissection 13
- Monoclonal (Antibody) 14
- Polyclonal (Antibody) 14
- Primary Antibody 14
- Primary Cells 14
- Secondary Antibody 14
- Tissue 15
- TABLE 3 MAJOR TISSUE TYPES AND CONSTITUENT CELLS 15
- Tissue Microarray 15
- INDUSTRY DEFINITION 16
- INDUSTRY BREAKDOWN 16
- Biospecimens 16
- TABLE 4 MAJOR BIOSPECIMENS USED IN RESEARCH AND DRUG DEVELOPMENT 17
- TABLE 5 BIOSPECIMENS LIFECYCLE 17
- Cell and Tissue Separation Products 18
- TABLE 6 MAJOR TYPES OF CELL AND TISSUE SEPARATION PRODUCTS USED IN
RESEARCH AND DRUG DEVELOPMENT 18
- Cell and Tissue Characterization Products 18
- TABLE 7 APPLICATIONS OF CELL AND TISSUE CHARACTERIZATION PRODUCTS IN
RESEARCH AND DRUG DEVELOPMENT 19
- PRODUCT BREAKDOWN 19
- Biospecimens 19
- History 19
- Types of Biospecimens 19
- Tissue Microarray 20
- History 20
- Frozen Arrays 20
- FFPE Arrays 21
- TMA Applications 21
- Cell and Tissue Dissociation 22
- Enzymatic Dissociators 22
- TABLE 8 COMMON ENZYMES USED FOR CELL AND TISSUE DISSOCIATION 22
- Mechanical Dissociators 22
- Bead Method 23
- Sonication 23
- Pressure Homogenizing 23
- Rotor-stator Homogenizing 23
- Manual Grinding 24
- Blade Homogenizing 24
- Magnetic Cell Separation Technology 24
- Technology 24
- Laser Microdissection 25
- History 25
- LMD Applications 25
- LMD Platforms 26
- Laser Microdissection and Pressure Catapulting 26
- Fusion Microdissection 26
- Flow Cytometry 26
- History 26
- Cytometer Types 27
- Analyzers 27
- Sorters 27
- Detection 27
- Clinical Applications 28
- Research Applications 28
- Research Antibodies 28
- History 28
- Antibody Types 29
- Primary Antibodies 29
- Secondary Antibodies 29
- Isotype Controls 30
- Antibody Specifications 30
- Host 30
- TABLE 9 HOST SPECIES USED IN GENERATING RESEARCH ANTIBODIES (SPECIES) 30
- Class/Isotype 30
- Target Species (Reactivity) 31
- Label 31
- TABLE 10 COMMON ANTIBODY LABELS (TYPE) 31
- Cell-Based Assays 31
- History 31
- Applications of Cell-Based Assays 32
- Types of Cell-Based Assays 32
- Signaling Assays 32
- Cell Viability/Death Assays 32
- Cell Proliferation Assays 33
- Cell Migration Assays 33
- High-Content Screening 34
- History 34
- HCS Applications 34
- HCS Instrumentation 35
- Confocal Machines 35
- Non-confocal Machines 35
- REGULATORY ISSUES 35
- HISTORY 35
- Biomedical Tissue Services 36
- American Tissue 37
- Willed Body Program 37
- Body World 37
- Bodies...the Exhibition 38
- BIOSPECIMEN REGULATORY STRUCTURE 38
- Federal Regulations 38
- Current Good Tissue Practices 38
- TABLE 11 INTERNATIONAL REGULATORY RULES & RULINGS GUIDING THE ACCESS/USE
OF HUMAN TISSUE IN RESEARCH AND DRUG DISCOVERY, 2001 - 2009 39
- State Regulations 39
Chapter-3: OVERVIEW 33
Chapter-4: INDUSTRY STRUCTURE AND COMPETITIVE ANALYSIS 19
- INDUSTRY PARTICIPANTS 40
- TISSUE MICROARRAYS 40
- TABLE 12 MAJOR COMPANIES IN THE TISSUE MICROARRAY MARKET 40
- TABLE12 (CONTINUED) 41
- CELL SEPARATION PRODUCTS 41
- TABLE 13 MAJOR COMPANIES IN THE CELL SEPARATION PRODUCT MARKET 41
- TABLE 13 (CONTINUED) 42
- RESEARCH ANTIBODIES 42
- TABLE 14 MAJOR COMPANIES IN THE RESEARCH ANTIBODIES MARKET 43
- TABLE 15 COMPANIES IN THE GMP ANTIBODY PRODUCTION MARKET 43
- TABLE 15 (CONTINUED) 44
- TABLE 15 (CONTINUED) 45
- TABLE 16 COMPANIES IN THE GMP ANTIBODY PRODUCTION MARKET, BY LOCATION,
2009 45
- TABLE 16 (CONTINUED) 46
- CELL-BASED ASSAYS 46
- TABLE 17 COMPANIES IN THE CELL-BASED ASSAY PRODUCT MARKET 47
- HIGH-CONTENT SCREENING PRODUCTS 47
- TABLE 18 COMPANIES IN THE HIGH CONTENT SCREENING INSTRUMENTATION PRODUCT
MARKET 48
- MARKET SHARES 48
- BIOSPECIMENS 48
- TABLE 19 MARKET SHARE OF COMMERCIAL BIOSPECIMEN VENDORS 2008 ($ MILLION,
%) 48
- LASER MICRODISSECTION 49
- TABLE 20 MARKET SHARE OF COMMERCIAL LASER MICRODISSECTION MARKET LEADERS
2009 ($ MILLION, %) 49
- FLOW CYTOMETRY 50
- TABLE 21 MARKET SHARE OF COMMERCIAL FLOW CYTOMETRY MARKET LEADERS, 2008 ($
MILLIONS) 50
- RESEARCH ANTIBODIES 50
- TABLE 22 MARKET SHARE OF COMMERCIAL RESEARCH ANTIBODY MARKET LEADERS, 2008
($ MILLIONS) 51
- HIGH CONTENT SCREENING/CELL-BASED ASSAYS 51
- TABLE 23 MARKET SHARE OF COMMERCIAL HIGH CONTENT SCREENING AND CELL-BASED
ASSAY INSTRUMENTATION MARKET LEADERS, 2009 ($ MILLIONS) 52
- TABLE 24 MARKET SHARE OF COMMERCIAL HIGH CONTENT SCREENING AND CELL-BASED
ASSAY REAGENT MARKET LEADERS, 2009 ($ MILLIONS) 52
- MERGERS, ACQUISITIONS, STRATEGIC ALLIANCES & PARTNERSHIPS 53
- BIOSPECIMENS 53
- TABLE 25 MAJOR BIOSPECIMEN INDUSTRY EVENTS, 2005 - 2009 53
- LASER MICRODISSECTION 54
- TABLE 26 MAJOR LASER MICRODISSECTION INDUSTRY EVENTS, 2004 - 2009 54
- FLOW CYTOMETRY 55
- TABLE 27 MAJOR FLOW CYTOMETRY INDUSTRY EVENTS, 2005 - 2009 55
- RESEARCH ANTIBODIES 55
- TABLE 28 MAJOR RESEARCH ANTIBODY INDUSTRY EVENTS, 2005 - 2009 56
- Notable Developments 57
- HIGH CONTENT SCREENING 57
- TABLE 29 MAJOR HIGH CONTENT SCREENING INDUSTRY EVENTS, 2004 - 2009 57
- TABLE 29 (CONTINUED) 58
Chapter-5: CELL AND TISSUE ANALYSIS TECHNOLOGIES 36
- INTRODUCTION 59
- BIOSPECIMEN TECHNOLOGIES 59
- TABLE 30 NEW PRODUCTS FROM BIOSPECIMEN MARKET COMPANIES 59
- TABLE 30 (CONTINUED) 60
- TABLE 30 (CONTINUED) 61
- TISSUE MICROARRAYS 61
- TABLE 31 PRODUCT SPECIFICATIONS OF TISSUE MICROARRAYS 62
- FIGURE 2 FLOW DIAGRAM FOR TISSUE MICROARRAY PRODUCTION 63
- Tissue Microarray Production 64
- Types of Tissue Microarrays 64
- Frozen Tissue Arrays 64
- FFPE Arrays 65
- TABLE 32 COMPARISON OF THE MAIN TYPES OF TISSUE MICROARRAY FORMATS 66
- Multi-sample Arrays 66
- Progression Arrays 67
- Prognosis Arrays 67
- Applications of TMA 67
- TABLE 33 EXAMPLE APPLICATIONS OF DIFFERENT TISSUE MICROARRAY PREPARATIONS
67
- TABLE 33 (CONTINUED) 68
- TABLE 34 COMMMON DISEASED TISSUES AVAILABLE IN TISSUE MICROARRAY FORMAT 68
- TABLE 34 (CONTINUED) 69
- New Developments in Tissue Microarray Technology 69
- TABLE 35 TISSUE MICROARRAY, TECHNOLOGY DEVELOPMENT 70
- Matrix Assembly 71
- TMA Content 71
- TMA Analysis Software 72
- TABLE 36 COMPARISON OF TISSUE MICROARRAY ANALYSIS SOFTWARE PACKAGES 73
- TABLE 36 (CONTINUED) 74
- CELL SEPARATION TECHNOLOGIES 75
- MECHANICAL AND ENZYMATIC SEPARATION 75
- Neural Stem Cells 75
- Neural Tissue 76
- Magnetic Separation 76
- Positive Selection 77
- Negative Selection 77
- Multi-step Selection 77
- TABLE 37 NEW MAGNETIC CELL SEPARATION PRODUCTS 77
- TABLE 37 (CONTINUED) 78
- Laser Microdissection 79
- Platforms 79
- LMPC 79
- Fusion Microdissection 79
- Microscopes, Objectives, Stages and Software 79
- TABLE 38 CURRENT LASER MICRODISSECTION INSTRUMENTS 80
- New Developments 80
- Live Cell Microdissection 80
- Remote Operation 81
- Flow Cytometry 81
- TABLE 39 COMMONLY USED FLUORESCENCE LABELS USED IN FLOW CYTOMETRY 81
- TABLE 39 (CONTINUED) 82
- Cytometer Types 82
- TABLE 40 NEW INSTRUMENTATION PRODUCTS FROM FLOW CYTOMETRY COMPANIES 83
- TABLE 40 (CONTINUED) 84
- Alternative Technologies 84
- Imaging Cytometers 84
- Laser Scanning Cytometers 84
- TABLE 41 NEW PRODUCTS FROM FLOW CYTOMETRY COMPANIES 85
- New Developments 85
- Benchtop Cytometers 85
- Multi-parametric Analyses 85
- CELL AND TISSUE ANALYSIS TECHNOLOGIES 86
- RESEARCH ANTIBODIES 86
- FIGURE 3 SCHEMATIC PRODUCTION OF MONOCLONAL AND POLYCLONAL ANTIBODIES 86
- New Developments 87
- Stem Cell Antibodies 87
- Modification-state Specific Antibodies 87
- New Fluorophores 88
- High-Content Screening 88
- FIGURE 4 BASIC SCHEMATIC OF A TYPICAL HIGH CONTENT SCREENING INSTRUMENT
88
- HCS Instrumentation 89
- Confocal Instruments 89
- Image Sectioning 89
- TABLE 42 FEATURES OF COMMON CONFOCAL HCS INSTRUMENTATION 90
- Widefield Instruments 90
- Illumination Sources 91
- Autofocus 91
- TABLE 43 FEATURES OF COMMON WIDEFIELD HCS INSTRUMENTATION 92
- Software 92
- HCS Applications 92
- Profiling Studies 93
- Screening Studies 93
- New Developments 93
- TABLE 44 NEW PRODUCTS FROM HCS COMPANIES 94
Chapter-6: PATENT LANDSCAPE 21
- INTRODUCTION 95
- CTA INDUSTRY 95
- IMPORTANT CONCEPTS 95
- Priority Dates 95
- Patent Cooperation Treaty 96
- IPC Codes 96
- METHODOLOGY 96
- PATENTS FOR BIOSPECIMEN VENDORS 97
- TABLE 45 NUMBER OF U.S. PATENTS FOR MAJOR BIOSPECIMEN VENDORS, 2009 (NO.
OF PATENTS, % OF PATENTS) 98
- TABLE 46 NUMBER OF INTERNATIONAL PATENTS FOR MAJOR BIOSPECIMEN VENDORS,
THROUGH 2009 (NO. OF PATENTS, % OF PATENTS) 98
- TISSUE MICROARRAY PATENTS 99
- TABLE 47 PATENT PUBLICATIONS FOR TISSUE MICROARRAY TECHNOLOGIES, BY YEAR,
2001 - 2009 (NO. OF PATENTS) 99
- TABLE 48 MAJOR PATENT ASSIGNEES FOR TISSUE MICROARRAY TECHNOLOGIES, 2001 -
2009 (AS OF JUNE 2009) 99
- TABLE 48 (CONTINUED) 100
- TABLE 49 MAJOR IPC CLASSES FOR TISSUE MICROARRAY PATENTS, 2001 - 2009 (NO.
OF PATENTS) 100
- SUMMARY 101
- PATENTS FOR CELL SEPARATION PRODUCT COMPANIES 102
- TABLE 50 NUMBER OF U.S. PATENTS FOR MAJOR CELL SEPARATION PRODUCT
COMPANIES, AS OF JUNE 1, 2009 (NO. OF PATENTS, PERCENT OF PATENTS) 103
- TABLE 51 NUMBER OF INTERNATIONAL PATENTS FOR MAJOR CELL SEPARATION PRODUCT
COMPANIES, AS OF JUNE 1, 2009 (NO. OF PATENTS, PERCENT OF PATENTS) 103
- LASER MICRODISSECTION PATENTS 104
- TABLE 52 PATENT PUBLICATIONS FOR LASER MICRODISSECTION TECHNOLOGIES, BY
YEAR, 1999 - 2009 (NO. OF PATENTS) 104
- TABLE 53 MAJOR PATENT ASSIGNEES FOR LASER MICRODISSECTION TECHNOLOGIES,
1999 - 2009 (NO. OF PATENTS) 105
- TABLE 54 MAJOR IPC CLASSES FOR LASER MICRODISSECTION PATENTS, 1999 - 2009
(NO. OF PATENTS) 106
- FLOW CYTOMETRY PATENTS 106
- TABLE 55 PATENT PUBLICATIONS FOR FLOW CYTOMETRY TECHNOLOGIES, BY YEAR,
1999 - 2009 (NO. OF PATENTS) 107
- TABLE 56 MAJOR PATENT ASSIGNEES FOR FLOW CYTOMETRY TECHNOLOGIES, 2001 -
2009 (NO. OF PATENTS) 107
- TABLE 57 NUMBER OF U.S. PATENTS FOR MAJOR FLOW CYTOMETRY COMPANIES, 1971 -
2009 (NO. OF PATENTS, PERCENT OF PATENTS) 108
- TABLE 58 MAJOR IPC CLASSES FOR FLOW CYTOMETRY PATENTS, 2001 - 2009 (NO. OF
PATENTS) 109
- SUMMARY 109
- PATENTS FOR CELL AND TISSUE ANALYSIS COMPANIES 110
- RESEARCH ANTIBODY PATENTS 110
- TABLE 59 NUMBER OF ANTIBODY-RELATED PATENTS FOR MAJOR RESEARCH ANTIBODY
COMPANIES, AS OF JUNE 1 2009 (NO. OF PATENTS) 111
- Licensing 111
- HIGH CONTENT SCREENING PATENTS 112
- TABLE 60 CELLOMICS PATENTS IN THE HIGH CONTENT SCREENING INDUSTRY 112
- TABLE 61 PATENT PUBLICATIONS RELATING TO HIGH CONTENT SCREENING, BY YEAR,
2004 - 2009 (NO. OF PATENTS) 113
- TABLE 62 MAIN INDUSTRY SEGMENT OF HIGH CONTENT SCREENING PATENT ASSIGNEES,
2004 - 2009 113
- CELL-BASED ASSAY PATENTS 114
- TABLE 63 PATENT PUBLICATIONS RELATING TO CELL-BASED ASSAYS, BY YEAR, 2001
- 2009 (NO. OF PATENTS) 114
- TABLE 64 MAIN INDUSTRY SEGMENT OF CELL-BASED ASSAY PATENT ASSIGNEES, 2001
- 2009 (%) 115
Chapter-7: END USERS 40
- INTRODUCTION 116
- TABLE 65 CELL AND TISSUE ANALYSIS PRODUCT END-USER INDUSTRIES 116
- TABLE 65 (CONTINUED) 117
- ACADEMIC RESEARCH 117
- TABLE 66 NATIONAL INSTITUTES OF HEALTH BUDGET, THROUGH 2009 ($ BILLIONS)
118
- TABLE 67 NATIONAL SCIENCE FOUNDATION BUDGET, THROUGH 2009 ($ BILLIONS) 118
- RESEARCH UNIVERSITIES 119
- TABLE 68 TOP 20 U.S. RESEARCH UNIVERSITIES RECEIVING FEDERAL SUPPORT, 2006
($ MILLIONS) 119
- TABLE 69 FEDERAL RESEARCH SUPPORT GROWTH RATES FOR THE TOP 20 FEDERALLY
FUNDED U.S. RESEARCH UNIVERSITIES, THROUGH 2006 ($ MILLIONS, % CAGR) 120
- TABLE 70 HIGHEST ANNUAL LIFE SCIENCES EXPENDITURES FOR THE TOP 20
FEDERALLY FUNDED U.S. RESEARCH UNIVERSITIES, 2006 ($ MILLIONS) 121
- Translational Research 121
- TABLE 71 MAJOR U.S. CLINICAL AND TRANSLATIONAL SCIENCE AWARD (CTSA)
CENTERS, BY LOCATION, 2009 122
- TABLE 71 (CONTINUED) 123
- TABLE 71 (CONTINUED) 124
- TABLE 71 (CONTINUED) 125
- Government Laboratories 125
- TABLE 72 LIST OF NIH RESEARCH LABS 125
- TABLE 73 NIH INTRAMURAL RESEARCH BUDGET, THROUGH 2009 ($ MILLIONS) 126
- Nonprofit Research Institutes 126
- TABLE 74 LIST OF THE LARGEST U.S. NONPROFIT RESEARCH INSTITUTES, 2008 ($
MILLION) 126
- TABLE 74 (CONTINUED) 127
- BIOPHARMACEUTICAL 127
- Drug Development Process 127
- Biotechnology Industry 128
- TABLE 75 ANNUAL BIOTECHNOLOGY R&D EXPENDITURES OF SELECT INTERNATIONAL
COUNTRIES ($ BILLIONS) 129
- TABLE 76 LIST OF NOTABLE BIOTECHNOLOGY INDUSTRY COMPANIES 129
- Pharmaceutical Industry 130
- TABLE 77 LIST OF NOTABLE PHARMACEUTICAL INDUSTRY COMPANIES 130
- TABLE 78 BIOPHARMACEUTICAL R&D SPENDING, THROUGH 2009 ($ BILLIONS) 131
- HEALTHCARE/CLINICAL 131
- Research Hospitals 131
- INTERNATIONAL ASPECTS 131
- Europe 131
- TABLE 79 TOTAL RESEARCHERS IN EUROPEAN COUNTRIES BY PERFORMANCE SECTOR,
2008 (#, X1,000) 132
- GLOBAL MARKET 132
- Trends in U.S. Research and Development 132
- TABLE 80 U.S. EXPENDITURES ON R&D FINANCING BY SECTOR, THROUGH 2014 ($
BILLIONS) 133
- TABLE 81 U.S. GROSS DOMESTIC EXPENDITURE ON R&D (GERD) FINANCING BY
SECTOR, THROUGH 2014 (%) 133
- Trends in International Research and Development 134
- TABLE 82 GROSS DOMESTIC EXPENDITURE ON R&D (GERD) BY THE PRIVATE BUSINESS
SECTOR IN EUROPEAN COUNTRIES, 2000-2008 (%) 134
- TABLE 83 GROSS DOMESTIC EXPENDITURE ON R&D (GERD) BY THE GOVERNMENT SECTOR
IN EUROPEAN COUNTRIES, 2000-2008 (%) 135
- MARKETS BY PRODUCTS 135
- Biospecimens 135
- Tissue Microarray Use 136
- TABLE 84 PUBMED INDEXED SCIENTIFIC PUBLICATIONS USING TISSUE MICROARRAY,
1998 - 2009 136
- TABLE 85 CLINICAL TRIALS USING TISSUE MICROARRAY, 2001 - 2009 136
- TABLE 85 (CONTINUED) 137
- TABLE 86 PROJECTED GLOBAL SALES OF BIOSPECIMENS, THROUGH 2014 (% MILLIONS)
137
- Cell Separation Products 137
- TABLE 87 PROJECTED GLOBAL SALES OF CSP, THROUGH 2014 ($ MILLIONS) 138
- Laser Microdissection 138
- TABLE 88 PUBMED INDEXED SCIENTIFIC PUBLICATIONS USING LASER CAPTURE
MICRODISSECTION, 1998 - 2009 139
- TABLE 89 CLINICAL TRIALS USING LASER MICRODISSECTON, 1999 - 2009 139
- TABLE 90 PROJECTED GLOBAL SALES OF LMD, THROUGH 2014 ($ MILLIONS) 140
- Flow Cytometry 140
- TABLE 91 PUBMED INDEXED SCIENTIFIC PUBLICATIONS USING FLOW CYTOMETRY OR
FLUORESCENCE ACTIVATED CELL SORTING, 1998 - 2009 140
- TABLE 92 CLINICAL TRIALS USING FLOW CYTOMETRY FLUORESCENCE ACTIVATED CELL
SORTING, BY LOCATION, 2009 (NO. OF TRIALS) 141
- TABLE 93 CLINICAL TRIALS USING FLOW CYTOMETRY OR FLUORESCENCE ACTIVATED
CELL SORTING, BY FUNDING SOURCE, 2002 - 2009 142
- TABLE 94 CLINICAL TRIALS USING FLOW CYTOMETRY OR FLUORESCENCE ACTIVATED
CELL SORTING, BY CONDITION CATEGORY, 2009 142
- TABLE 95 PROJECTED GLOBAL SALES OF THE FLOW CYTOMETRY INDUSTRY THROUGH
2014 ($ MILLIONS) 143
- Cell and Tissue Characterization Products 143
- TABLE 96 PROJECTED GLOBAL SALES OF CTC PRODUCTS, THROUGH 2014 ($
MILLIONS) 143
- Research Antibodies 144
- TABLE 97 PROJECTED GLOBAL SALES OF CTC PRODUCTS, THROUGH 2014 ($
MILLIONS) 144
- HCS/CBA 144
- TABLE 98 PROJECTED GLOBAL SALES OF CTC PRODUCTS, THROUGH 2014 ($
MILLIONS) 144
- TABLE 99 HCS/CBA PRODUCT SEGMENTS, 2009 (%) 145
- MARKETS BY END-USER SEGMENTS 145
- TABLE 100 GLOBAL END-USER MARKETS FOR CELL AND TISSUE ANALYSIS PRODUCTS,
THROUGH 2014 ($ MILLIONS) 146
- Academic Research 146
- TABLE 101 ACADEMIC RESEARCH END-USER SEGMENTS, 2009 (%) 146
- TABLE 102 GLOBAL MARKETS FOR CELL AND TISSUE ANALYSIS PRODUCTS IN
ACADEMIC RESEARCH, THROUGH 2014 ($ MILLIONS) 147
- Biopharmaceutical 147
- TABLE 103 BIOPHARMACEUTICAL END-USER SEGMENTS, 2009 (%) 147
- TABLE 104 MARKETS FOR CELL AND TISSUE ANALYSIS PRODUCTS IN
BIOPHARMACEUTICAL RESEARCH, THROUGH 2014 ($ MILLIONS) 148
- TABLE 105 OTHER MARKETS FOR CELL AND TISSUE ANALYSIS PRODUCTS, THROUGH
2014 ($ MILLIONS) 149
- GEOGRAPHIC MARKETS 149
- General Trends 149
- TABLE 106 REAL GDP GROWTH RATES IN THE UNITED STATES, 2005 - 2010 (PERCENT
CHANGE OVER PREVIOUS YEAR) 150
- TABLE 107 REAL GDP GROWTH RATES IN EUROPEAN COUNTRIES, 2005 - 2010
(PERCENT CHANGE OVER PREVIOUS YEAR) 150
- Global Market Trends 151
- TABLE 108 GEOGRAPHIC MARKETS FOR CELL AND TISSUE ANALYSIS PRODUCTS,
THROUGH 2014 ($ MILLIONS) 151
- Biospecimens 151
- TABLE 109 BIOSPECIMEN GEOGRAPHIC MARKET SHARES, 2009 AND 2014 (PERCENT OF
GLOBAL SALES) 152
- TABLE 110 GEOGRAPHIC MARKETS FOR BIOSPECIMENS, THROUGH 2014 ($ MILLIONS)
152
- CSP 153
- TABLE 111 CELL SEPARATION PRODUCT GEOGRAPHIC MARKET SHARES, 2009 AND 2014
(PERCENT OF GLOBAL SALES) 153
- TABLE 112 GEOGRAPHIC MARKETS FOR CELL SEPARATION PRODUCTS, THROUGH 2014
($ MILLIONS) 154
- CTC Products 154
- TABLE 113 CTC PRODUCT GEOGRAPHIC MARKET SHARES, 2009, AND 2014 (PERCENT OF
GLOBAL SALES) 154
- TABLE 114 GEOGRAPHIC MARKETS FOR CELL AND TISSUE CHARACTERIZATION
PRODUCTS, THROUGH 2014 ($ MILLIONS) 155
Chapter-8: COMPANY PROFILES 28
- BIOSPECIMEN VENDORS (BSV) 156
- TABLE 115 PRODUCTS AND SERVICES OFFERED BY BIOSPECIMEN VENDORS (BSV), 2009
(X REPRESENTS PRODUCT OR SERVICE PROVIDED) 156
- AMERICAN TYPE CULTURE COLLECTION (ATCC) 156
- ANALYTICAL BIOLOGICAL SERVICES, INC. 157
- ASTERAND PLC. 158
- BIOCHAIN INSTITUTE, INC. 159
- BIOSERVE BIOTECHNOLOGIES LTD. 159
- CAPITAL BIOSCIENCES, INC. 160
- CELLECTA, INC. 161
- CURELINE, INC. 161
- CYBRDI, INC. 162
- FOLIO BIOSCIENCES 163
- ILSBIO, LLC. 163
- LIFESPAN BIOSCIENCES, INC. 164
- PROMEDDX, LLC 165
- U.S. BIOMAX, INC. 166
- CELL SEPARATION PRODUCT (CSP) COMPANIES 167
- TABLE 116 PRODUCTS AND SERVICES OFFERED BY CELL SEPARATION PRODUCT (CSP)
COMPANIES, 2009 (X REPRESENTS PRODUCT OR SERVICE PROVIDED) 167
- ACCURI CYTOMETERS, INC. 167
- BECKMAN COULTER, INC. 168
- BD BIOSCIENCES 168
- CARL ZEISS MICROIMAGING, GMBH 169
- LEICA MICROSYSTMES, GMBH 170
- MILLIPORE 170
- MILTENYI BIOTEC 171
- MDS ANALYTICAL TECHNOLOGIES 172
- MOLECULAR MACHINES & INDUSTRIES, GMBH 172
- PARTEC, GMBH 173
- STEM CELL TECHNOLOGIES 173
- WORTHINGTON BIOCHEMCIAL CORPORATION 174
- CELL AND TISSUE CHARACTERIZATION COMPANIES 175
- TABLE 117 PRODUCTS AND SERVICES OFFERED BY CELL & TISSUE CHARACTERIZATION
COMPANIES, 2009 (X REPRESENTS PRODUCT OR SERVICE PROVIDED) 175
- ABCAM, PLC. 175
- CELL SIGNALING TECHNOLOGY, INC. 176
- CELLUMEN, INC. 176
- EBIOSCIENCE, INC. 177
- GE HEALTHCARE BIOSCIENCES 177
- INVITROGEN CORPORATION 178
- MBL INTERNATIONAL 179
- PERKINELMER, INC. 179
- PLATYPUS TECHNOLOGIES, LLC 180
- PROMEGA CORPORATION 180
- ROCHE APPLIED SCIENCE 180
- SIGMA-ALDRICH, INC. 181
- THERMO FISHER SCIENTIFIC, INC. 182
- APPENDIX: GLOSSARY 183
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