Report: Nanostructured Materials for the Biomedical, Pharmaceutical, & Cosmetic Markets TOC

Nanostructured Materials for the Biomedical, Pharmaceutical, & Cosmetic Markets
Chapter 1 - EXECUTIVE SUMMARY
- Summary Table: TOTAL WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL AND COSMETIC APPLICATIONS, THROUGH 2012 ($ MILLIONS)
- Summary Figure: TOTAL WORLD MARKET SHARE PROJECTIONS FOR BIOMEDICAL, PHARMACEUTICAL AND COSMETIC APPLICATIONS OF NANOPARTICLES, 2006-2012 (%)
Chapter 2 - OVERVIEW
- TERMINOLOGY
- PRODUCTS AND PROPERTIES
Table 1 SUMMARY OF PROPERTY CHANGES AT THE NANOCRYSTALLINE-SIZE SCALE
- CATALYTIC
- ELECTRICAL
- MAGNETIC
  - Magnetic (Continued)
- MECHANICAL
- OPTICAL AND ELECTRONIC
HISTORICAL BACKGROUND
- HISTORICAL BACKGROUND (CONTINUED)
Figure 1 TIMELINE OF INDUSTRY EVENTS, 1920-2000
Chapter 3 - NANOPARTICLE TECHNOLOGIES
- PARTICLE PRODUCTION
  - TECHNOLOGIES FOR PRODUCING INORGANIC NANOPARTICLES
- Table 2 CLASSES OF INORGANIC NANOPARTICLE PRODUCTION METHODS
Table 3 PARTICLE PRODUCTION TECHNOLOGIES AND COMPANIES USING THEM
Table 3 (CONTINUED)
- Gas-Phase Processing
  - Gas Condensation with Thermal Evaporation
  - Vacuum Evaporation on Running Liquids (VERL)
Figure 2 SCHEMATIC OF THE MODIFIED VERL PROCESS TO PRODUCE METAL NANOSUSPENSIONS
- Thermal Plasma Synthesis
- Combustion Synthesis
Wet-Chemical Processes
- Chemical Precipitation
- Hydrothermal Processing
- Sol-Gel Processing
Figure 3 SOL-GEL SYNTHESIS FLOW CHART
- Solid-State Processes
  - High-Energy Milling
  - Mechanochemical Synthesis
TECHNOLOGIES FOR PRODUCING ORGANIC NANOPARTICLES
- Lipids
- Dendrimers
PRODUCING STABLE DISPERSIONS
PRODUCTION OF COATINGS, COMPONENTS, AND DEVICES
- COATINGS
  - Slurry-Coating Routes
  - Dip Coating
  - Spin Coating
  - Comparison with Vapor-Deposition Techniques
Table 4 COMPARISON OF COATING TECHNOLOGIES
- Electrophoretic Deposition
- Jet-Printing Process
- Thermal Spray Coating
- Direct Production of Nanostructured Coatings and Bulk Solids
- Electrodeposition
- Amorphous Crystallization
COMPONENTS AND DEVICES
- Consolidation of Nanoparticles into Components
  - Three-Dimensional Gel Lamination
  - Dynamic-Magnetic Consolidation
  - Field-Assisted Sintering Techniques
  - Quasi-Isostatic Pressure Process
  - Shockwave Compaction
  - Sinter Forging
  - Severe Plastic Deformation
SELF-ASSEMBLY OF NANOPARTICLES
- "BRICKS-AND-MORTAR"APPROACH ORDERS GOLD PARTICLES
- MICELLES ENABLE ASSEMBLY OF NANOLAMINATES
- VIRAL BIOTEMPLATE ORGANIZES NANOMETAL PARTICLES INTO ARRAYS
- MAGNETIC NANOPARTICLE DISPERSIONS SELF-ASSEMBLE INTO ORDERED ARRAYS
U.S. PATENT ANALYSIS
- Introduction
- Trends by Country
- Trends by Assignee
Figure 4 U.S. PATENT TRENDS BY ASSIGNEE' S COUNTRY (NUMBER OF PATENTS ISSUED BETWEEN 10/15/2005 AND 10/15/2007)
Figure 5 SHARES OF U.S. PATENTS BY ASSIGNEE (%)
Table 5 COMPANIES AND INSTITUTIONS AWARDED TWO OR MORE NANOMATERIAL-RELATED PATENTS BETWEEN OCTOBER 15, 2005 AND OCTOBER 15, 2007
- Trends by Emphasis: Production versus Application
Figure 6 SHARES OF PATENTS ISSUED BY EMPHASIS (%)
Chapter 4 - INDUSTRY STRUCTURE
- PRODUCERS
Table 6 COMPANIES WORLDWIDE INVOLVED IN NANOPARTICLE DEVELOPMENT OR PRODUCTION FOR BIOMEDICAL AND COSMETIC APPLICATIONS
Table 7 (CONTINUED)
Figure 7 GEOGRAPHICAL DISTRIBUTION OF COMPANIES INVOLVED IN NANOPARTICLE DEVELOPMENT OR PRODUCTION FOR BIOMEDICAL AND COSMETIC APPLICATIONS (%)
- COMMERCIAL PRODUCTS
- NANOPARTICLE PRICING
Table 7 FACTORS THAT IMPACT THE PRICING OF NANOPARTICLES
- COMMERCIALIZATION STRATEGIES
- INTERNATIONAL COMPETITION
- REGULATORY ENVIRONMENT
- REGULATION IN THE U.S.
  - U.S. Food and Drug Administration
    - Medical Devices
    - Drugs and Biologicals
    - Combination Products
  - U.S. Environmental Protection Agency
    - Other Agencies
- REGULATION OVERSEAS
GOVERNMENT FUNDING
- NATIONAL NANOTECHNOLOGY INITIATIVE (NNI)
Table 8 NNI BUDGET REQUESTS FOR NATIONAL INSTITUTES OF HEALTH, 2004-2008 ($ MILLIONS)
Figure 8 RECENT TRENDS IN U.S. NATIONAL NANOTECHNOLOGY INITIATIVE SPENDING ON BIOMEDICAL R&D NANOTECHNOLOGY RESEARCH, FY 2004-2008 (BUDGET REQUESTS IN $ MILLIONS)
- THE ADVANCED TECHNOLOGY PROGRAM (ATP)
  - Background
  - Relevant Awards
Table 9 ADVANCED TECHNOLOGY PROGRAM AWARDS RELATED TO BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS OF NANOPARTICLES, 1999-2008 ($ MILLIONS)
- SMALL BUSINESS INNOVATION RESEARCH (SBIR) AND SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAMS
- Background
- Relevant Awards
Table 10 RECIPIENTS OF THREE OR MORE NANOMATERIALS-RELATED PHASE I SBIR/STTR AWARDS, 1991-2007 (NUMBERS ARE LOWER-BOUNDS)
Chapter 5 - WORLD MARKETS
- INTRODUCTION
- WORLD MARKETS OVERVIEW
  - OVERALL MARKET FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS
Figure 9 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL AND COSMETIC APPLICATIONS, 2006-2012 ($ MILLIONS)
Figure 10 WORLD MARKET FORECAST FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS, 2006-2012 (MILLION KG)
- MARKET SEGMENTATION BY APPLICATION
  - Segmentation in Terms of Value
Table 11 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS BY TYPE OF APPLICATION IN TERMS OF VALUE, THROUGH 2012 ($ MILLIONS)
Table 11 (CONTINUED)
Figure 11WORLD NANOPARTICLES MARKET SHARE PROJECTIONS BY APPLICATION, 2006-2012 (%)
- Segmentation in Terms of Volume
Table 12 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS BY APPLICATION IN TERMS OF VOLUME, THROUGH 2012 (KG)
- MARKET SEGMENTATION BY MATERIAL TYPE
  - Segmentation in Terms of Value
Table 13 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS BY MATERIAL TYPE IN TERMS OF VALUE, THROUGH 2012 ($ MILLIONS)
Figure 12WORLD MARKET SHARE PROJECTIONS FOR NANOPARTICLES BY MATERIAL TYPE, 2006-2012 (%)
- Segmentation in Terms of Volume
Table 14 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS BY MATERIAL TYPE IN TERMS OF VOLUME, THROUGH 2012 (KG)
- DETAILED MARKET ANALYSIS
  - ANTIMICROBIAL MATERIALS
    - Background
    - Materials, Production, and Technical Requirements
    - Commercial and Regulatory Status
      - Antimicrobial Materials
Table 15 ANTIMICROBIAL PRODUCTS INCORPORATING SILVER NANOPARTICLES
- Nucryst Pharmaceuticals
- Surfacine Development Co.
- Try Co.
- Fraunhofer Institute
- Mineral Supplements
World Markets
Figure 13 PROJECTED TRENDS IN THE WORLD MARKET FOR NANOPARTICULATE SILVER USED IN ANTIMICROBIAL APPLICATIONS, 2006-2012 ($ MILLIONS)
- Antimicrobial Dressings
Table 16 WORLD MARKET PROJECTIONS FOR NANOPARTICULATE SILVER, THROUGH 2012 (KG/$ MILLIONS)
- Dietary Supplements
BIOLOGICAL DETECTION AND LABELING
- Background
- Materials, Production, and Technical Requirements
Table 17 BASIC REQUIREMENTS OF DIAGNOSTIC TESTS
- Commercial and Regulatory Status
  - Established Applications
    - Colloidal Gold
Table 18 RAPID DIAGNOSTIC TESTS THAT USE GOLD NANOPARTICLES AS LABELS
- Nanoprobes, Inc.
- Orasure Technologies, Inc.
- Dendrimers
- Emerging Technologies and Applications
Table 19 EMERGING NANOPARTICLE-BASED TECHNOLOGIES FOR BIODETECTION AND LABELING BY COMPANY
Table 20 COMPARISON OF VARIOUS TYPES OF EMERGING NANOPARTICULATE LABELING TECHNOLOGIES
- BioCrystal, Ltd.
- Evident Technologies
- MagnaBioSciences, LLC
- Microcosm, Inc.
- Nanocrystal Technologies, LP
- Nanosphere, Inc.
- NymoxPharmaceutical Corp.
- Quantum Dot Corp.
Table 21 COMPARISON BETWEEN QDOTS AND CONVENTIONAL ORGANIC DYES
- World Markets
Table 22 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIODETECTION AND LABELING APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
Figure 14 PROJECTED TRENDS IN THE WORLD MARKET FOR NANOPARTICLES USED IN BIODETECTION AND LABELING APPLICATIONS, 2006-2012 ($ MILLIONS)
- Colloidal Gold
Table 23 WORLD MARKET PROJECTIONS FOR NANOPARTICULATE GOLD USED IN BIOLABELING APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
- Dendrimers
Table 24 WORLD MARKET PROJECTIONS FOR DENDRIMERS USED IN BIOLABELING APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
Semiconductor Nanoparticles
Table 25 WORLD MARKETPROJECTIONS FOR SEMICONDUCTOR NANOPARTICLES USED IN BIOLABELING APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
- Superparamagnetic Particles
Table 26 WORLD MARKET PROJECTIONS FOR SUPERPARAMAGNETIC NANOPARTICLES USED IN BIOLABELING APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
- BIOMAGNETIC SEPARATIONS
  - Background
  - Materials, Production, and Technical Requirements
    - Commercial and Regulatory Status
Table 27 PRODUCERS OF SUPERPARAMAGNETIC MICROSPHERES FOR BIOLOGICAL SEPARATION APPLICATIONS
- World Markets
Table 28 WORLD MARKETS FOR IRON OXIDE NANOPARTICLES IN BIOMAGNETIC SEPARATIONS, THROUGH 2012 (KG/$ MILLIONS)
Figure 15 PROJECTED TRENDS IN THE WORLD MARKET FOR NANOPARTICULATE IRON OXIDE USED IN BIOSEPARATION APPLICATIONS, 2006-2012 ($ MILLIONS)
- DRUG DELIVERY
  - Background
Table 29 CRITERIA FOR A NANOPARTICULATE DRUG DELIVERY VEHICLE
- Materials, Production, and Technical Requirements
- Commercial and Regulatory Status
Table 30 COMPANIES ACTIVE IN THE DEVELOPMENT OF NANOPARTICLES FOR DRUG-DELIVERY APPLICATIONS
- Cytimmune Sciences
Table 31 TIMELINE OF NEW DRUG DEVELOPMENT PROCESS
- PowderMed, Ltd.
- SkyePharma
- Starpharma
- World Markets
Table 32 WORLD MARKET PROJECTIONS FOR DENDRIMER-BASED DRUG DELIVERY SYSTEMS, THROUGH 2012 (KG/$ MILLIONS)
- MAGNETIC RESONANCE IMAGING (MRI) CONTRAST AGENTS
  - Background
Table 33 TYPES OF CONTRAST AGENTS USED FOR MRI IMAGING
- Materials, Production, and Technical Requirements
Commercial and Regulatory Status
Table 34 SUPERPARAMAGNETIC IRON OXIDE CONTRAST MEDIA: REGULATORY AND MARKETING STATUS
- World Markets
Table 35 WORLD MARKET PROJECTIONS FOR NANOPARTICULATE IRON OXIDE USED IN MRI CONTRAST MEDIA, THROUGH 2012 (KG/$ MILLIONS)
Figure 16 PROJECTED TRENDS IN THE WORLD MARKET FOR NANOPARTICULATE IRON OXIDE USED IN MRI CONTRAST APPLICATIONS, 2006-2012 ($ MILLIONS)
- TRANSFECTION REAGENTS
  - Background
  - Materials, Production, and Technical Requirements
  - Commercial and Regulatory Status
  - World Markets
Table 36 WORLD MARKET PROJECTIONS FOR DENDRIMERS USED IN TRANSFECTON REAGENTS, THROUGH 2012
Figure 17 PROJECTED TRENDS IN THE WORLD MARKET FOR DENDRIMERS USED IN TRANSFECTION REAGENTS, 2006-2012 ($ MILLIONS)
- ANTIOXIDANTS
  - Background
  - Materials, Production, and Technical Requirements
  - Commercial and Regulatory Status
- World Markets
Table 37 WORLD MARKET PROJECTIONS FOR SILICA HYDRIDE NANOPARTICLES USED IN NUTRACEUTICALS, THROUGH 2012 (KG/$ MILLIONS)
Figure 18 PROJECTED TRENDS IN THE WORLD MARKET FOR SILICA HYDRIDE NANOPARTICLES USED IN ANTIOXIDANT NUTRACEUTICAL, 2006-2012 ($ MILLIONS)
- ORTHOPEDIC AND DENTAL APPLICATIONS
  - Background
- Materials, Production, and Technical Requirements
- Commercial and Regulatory Status
Table 38 COMPANIES ACTIVE IN DEVELOPING NANOPARTICLE-BASED BIOACTIVE CERAMICS
- World Markets
Table 39WORLD MARKET PROJECTIONS FOR NANOPARTICLE-BASED SYNTHETIC BONE AND TOOTH ENAMELS, THROUGH 2012 (KG/$ MILLIONS)
Figure 19 PROJECTED TRENDS IN THE WORLD MARKET FOR NANOPARTICULATE HYDROXYAPATITE, 2006-2012 ($ MILLIONS)
- World Markets (Continued)
SUNSCREENS AND UV-PROTECTIVE COSMETICS
- Background
Table 40 SUNSCREEN INORGANIC AND ORGANIC ACTIVE INGREDIENTS
- Materials, Production, and Technical Requirements
Table 41 TECHNICAL REQUIREMENTS FOR NANOPARTICLES IN UV-SHIELDING APPLICATIONS
- Commercial and Regulatory Status
Table 42 PRODUCERS OF TIO2 AND ZNO PARTICLES AND DISPERSIONS
- Commercial and Regulatory Status (Continued)
Table 43 SUNSCREEN AND DAILY-USE SKIN PROTECTION PRODUCTS CONTAINING NANOPARTICULATE TIO2 AND ZNO
- Recent Developments
  - Process for Preparing Passivated TiO2 Nanoparticles
  - Titanium Dioxide Coated with Silicon Dioxide
  - Coated TiO2 Nanoparticles
- World Markets
Table 44 PROJECTED TRENDS IN WORLDWIDE SUNSCREEN SALES, THROUGH 2012 ($ BILLIONS)
Figure 20 PROJECTED TRENDS IN THE WORLD MARKET FOR TIO2 AND ZNO NANOPARTICLES USED IN SUNCREENS AND OTHER SKIN CARE PRODUCTS, 2006-2012 ($ MILLIONS)
Table 45 WORLD MARKET PROJECTIONS FOR TIO2 AND ZNO NANOPARTICLES IN SUNSCREEN APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
Chapter 6 - COMPANY PROFILES
- ADVANCED NANOTECHNOLOGY, LTD.
- AMAG PHARMACEUTICALS, INC.
- ALTAIR NANOTECHNOLOGIES, INC.
- ANGSTROM MEDICA, INC.
- APHIOS CORP.
- ARGONIDE CORP.
- BANGS LABORATORIES, INC.
- BASF AG
- BERKELEY ADVANCED BIOMATERIALS, INC.
- BIOPHAN TECHNOLOGIES, INC.
- CAPSULUTION NANOSCIENCE AG
- CYTIMMUNE SCIENCES, INC.
- DENDRITECH, INC.
- DENDRITIC NANOTECHNOLOGIES, INC.
- DOW CHEMICAL CO.
- DONG SEO, INC.
- DYNAL BIOTECH ASA
- ELEMENTIS SPECIALTIES
- EMD CHEMICALS, INC.
- EVIDENT TECHNOLOGIES
- EVONIK DEGUSSA GMBH
- FLAMEL TECHNOLOGIES S.A.
- INFRAMAT CORP.
- INVITROGEN CORP.
- ISHIHARA SANGYO KAISHA, LTD.
- KEMIRA SPECIALTY
- MAGNABIOSCIENCES, LLC
- MICROCOSM, INC.
- MICROMOD PARTIKELTECHNOLOGIE GMBH
- NANOCARRIER CORP., LTD.
- NANOPHASE TECHNOLOGIES CORP.
- NANOPROBES, INC.
- NANOSPHERE, INC.
- NOVAVAX, INC.
- NUCRYST PHARMACEUTICALS
- NYMOX PHARMACEUTICAL CORP.
- ORASURE TECHNOLOGIES, INC.
- ORTHOVITA, INC.
- OSI PHARMACEUTICALS, INC.
- PHARMASOL GMBH
- POLYSCIENCES, INC.
- POWDERMED, LTD.
- QUANTUM DOT CORP.
- QIAGEN N.V.
- RBC LIFE SCIENCES, INC.
- SACHTLEBEN CHEMIE GMBH
- SHOWA DENKO K.K.
- SKYEPHARMA, PLC
- SOMALOGIC, INC.
- STARPHARMA HOLDINGS, LTD.
- SURFACINE DEVELOPMENT CO.
- TAYCA CORP.

Nanostructured Materials for the Biomedical, Pharmaceutical, & Cosmetic Markets

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