Excipients in Pharmaceuticals

Table of Contents

Chapter- 1: INTRODUCTION -- Complimentary 3

• REASON FOR THE STUDY 1
• GOALS AND OBJECTIVES 1
• AUDIENCE 1
• SCOPE OF REPORT 2
• METHODS AND SOURCES 2
• ANALYST CREDENTIALS 2
• RELATED BCC REPORTS 3
• BCC ONLINE SERVICES 3
• DISCLAIMER 3

Chapter-2: SUMMARY 6

• SUMMARY TABLE GLOBAL EXCIPIENT MARKET BY MATERIAL TYPE, THROUGH 2014 ($ MILLIONS) 4
• SUMMARY FIGURE GLOBAL EXCIPIENT MARKET, 2009 AND 2014 ($ MILLIONS) 5
• SUMMARY (CONTINUED) 6
• SUMMARY (CONTINUED) 7
• SUMMARY (CONTINUED) 8
• SUMMARY (CONTINUED) 9

Chapter-3: OVERVIEW 31

• MR. BLECHER' S LETTER 10
• WHAT IS AN EXCIPIENT? 11
• WHAT IS AN EXCIPIENT? (CONTINUED) 12
• THE PHARMACEUTICALS INDUSTRY IN TURMOIL: 2000 TO TODAY 12
• THE PHARMACEUTICALS INDUSTRY ...(CONTINUED) 13
• THE KNOWLEDGE CRISIS 14
• THE KNOWLEDGE CRISIS (CONTINUED) 15
• THE KNOWLEDGE CRISIS (CONTINUED) 16
• THE NEED FOR NEW EXCIPIENTS 17
• THE NEED FOR NEW EXCIPIENTS (CONTINUED) 18
• A NOTE ABOUT DIRECT COMPRESSION 19
• COPROCESSING IS SPLENDID, BUT IT IS NOT ENOUGH 20
• QBD AND THE GLOBAL SUPPLY CHAIN CRISIS: TWO TIDAL WAVES 21
• HOW AND WHY THE QUALITY APPROACH CAME TO PHARMA 22
• HOW AND WHY THE QUALITY ...(CONTINUED) 23
• HOW AND WHY THE QUALITY ...(CONTINUED) 24
• HOW AND WHY THE QUALITY ...(CONTINUED) 25
• THE BASICS OF QBD IN 1,000 WORDS 26
• THE BASICS OF QBD IN 1,000 WORDS (CONTINUED) 27
• THE BASICS OF QBD IN 1,000 WORDS (CONTINUED) 28
• THE GLOBAL SUPPLY CHAIN CRISIS 29
• THE GLOBAL SUPPLY CHAIN CRISIS (CONTINUED) 30
• THE GLOBAL SUPPLY CHAIN CRISIS (CONTINUED) 31
• CHRONOLOGY, PART II 32
• CHRONOLOGY, PART II (CONTINUED) 33
• CHRONOLOGY, PART II (CONTINUED) 34
• CHRONOLOGY, PART II (CONTINUED) 35
• CHRONOLOGY, PART II (CONTINUED) 36
• IS THE WORKFORCE UP TO IT? 37
• A NOTE ON THE RECESSION 38
• THE REGULATORY SCENE 38
• THE REGULATORY SCENE (CONTINUED) 39
• THE REGULATORY SCENE (CONTINUED) 40

Chapter-4: GLOBAL EXCIPIENT MARKET: SEVERAL BASIC FIGURES 7

• FIGURE 1 GLOBAL EXCIPIENT MARKET SHARE BY CATEGORY OF MATERIAL, 2009 (%) 41
• FIGURE 2 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF ORGANIC CHEMICAL, 2009 (%) 42
• FIGURE 3 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF INORGANIC CHEMICAL, 2009 (%) 43
• FIGURE 4 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF USP WATER, 2009 (%) 44
• FIGURE 5 GLOBAL EXCIPIENT MARKET SHARE BY FUNCTIONAL USE, 2009 (%) 45
• FIGURE 6 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF DELIVERY SYSTEM, 2009 (%) 46
• FIGURE 7 GLOBAL EXCIPIENT MARKET FOR FINISHED PRODUCTS BY TYPE (RX AND OTC), 2009 (%) 47

Chapter-5: CHEMICAL COMPOUNDS 157

• CHEMICAL COMPOUNDS 48
• MARKET SIZE 49
• TABLE 1 GLOBAL EXCIPIENT MARKET VALUE BY MATERIAL TYPE, THROUGH 2014 ($ MILLIONS) 49
• TABLE 2 GLOBAL EXCIPIENT MARKET VOLUME BY MATERIAL TYPE, THROUGH 2014 (LBS MILLIONS) 50
• ORGANIC CHEMICALS 50
• MARKET SIZE FOR ORGANIC CHEMICALS 50
• TABLE 3 GLOBAL ORGANIC CHEMICAL EXCIPIENT MARKET VALUE BY TYPE, THROUGH 2014 ($ MILLIONS) 51
• TABLE 4 GLOBAL ORGANIC CHEMICAL EXCIPIENT MARKET VOLUME BY TYPE, THROUGH 2014 (LBS MILLIONS) 51
• CARBOHYDRATES 51
• Market Size 51
• TABLE 5 GLOBAL CARBOHYDRATE EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 52
• TABLE 6 GLOBAL CARBOHYDRATE EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 52
• Celluloses 52
• Market Size 53
• TABLE 7 GLOBAL CELLULOSE EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 53
• TABLE 8 GLOBAL CELLULOSE EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 53
• Microcrystalline Cellulose 53
• Market Size 54
• TABLE 9 GLOBAL MCC EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 54
• Cellulose Ethers 54
• Market Size 55
• TABLE 10 GLOBAL CELLULOSE ETHER EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 55
• Cellulose Esters 55
• Market Size 55
• TABLE 11 GLOBAL CELLULOSE ESTER EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 56
• Carboxymethyl Cellulose and Croscarmellose Sodium 56
• Market Size 57
• TABLE 12 GLOBAL CMC AND CROSCARMELLOSE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 57
• Sugars 57
• Market Size 57
• TABLE 13 GLOBAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 58
• TABLE 14 GLOBAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2014 (MILLION LBS) 58
• Actual Sugars 58
• Market Size 58
• TABLE 15 GLOBAL ACTUAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 59
• TABLE 16 GLOBAL ACTUAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 59
• Lactose 59
• Market Size 60
• TABLE 17 GLOBAL LACTOSE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 60
• Sucrose 60
• Market Size 60
• TABLE 18 GLOBAL SUCROSE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 61
• Dextrose (Glucose) 61
• Market Size 61
• TABLE 19 GLOBAL DEXTROSE (GLUCOSE) EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 61
• Sugar Alcohols 61
• Market Size 62
• TABLE 20 GLOBAL SUGAR ALCOHOL (POLYOL) EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 62
• TABLE 21 GLOBAL SUGAR ALCOHOL (POLYOL) EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 62
• Sorbitol 62
• Market Size 63
• TABLE 22 GLOBAL SORBITOL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 63
• Mannitol 63
• Market Size 63
• TABLE 23 GLOBAL MANNITOL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 64
• Other Sugar Alcohols 64
• Market Size 64
• TABLE 24 GLOBAL OTHER SUGAR ALCOHOL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 64
• Maltitol 65
• Xylitol 65
• Erythritol 65
• Isomalt 65
• Tagatose 66
• Trehalose 66
• Artificial Sweeteners 66
• Market Size 66
• TABLE 25 GLOBAL ARTIFICIAL SWEETENER EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 67
• Aspartame 67
• Neotame 67
• Acesulfame-K 68
• Saccharin 68
• Sucralose 68
• Starches 69
• Market Size 69
• TABLE 26 GLOBAL STARCHES EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 69
• TABLE 27 GLOBAL STARCHES EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 70
• Dried Starch 70
• Market Size 70
• TABLE 28 GLOBAL DRIED STARCH EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 70
• Modified Starch 71
• Market Size 71
• TABLE 29 GLOBAL MODIFIED STARCH EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 71
• Converted Starch 71
• Market Size 72
• TABLE 30 GLOBAL CONVERTED STARCH EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 72
• PETROCHEMICALS 72
• Market Size 72
• TABLE 31 GLOBAL PETROCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 73
• TABLE 32 GLOBAL PETROCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 73
• Glycols 73
• Market Size 74
• TABLE 33 GLOBAL GLYCOL EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 74
• TABLE 34 GLOBAL GLYCOL EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 74
• Polyethylene Glycol 74
• Market Size 75
• TABLE 35 GLOBAL PEG EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 75
• Propylene Glycol 75
• Market Size 75
• TABLE 36 GLOBAL PG EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 76
• Povidones 76
• Market Size 76
• TABLE 37 GLOBAL PVP EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 77
• Mineral Hydrocarbons 77
• Market Size 77
• TABLE 38 GLOBAL MINERAL HYDROCARBON EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 77
• TABLE 39 GLOBAL MINERAL HYDROCARBON EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 78
• Petrolatum 78
• Market Size 78
• TABLE 40 GLOBAL PETROLATUM EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 79
• Mineral Waxes 79
• Market Size 79
• TABLE 41 GLOBAL MINERAL WAX EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 79
• Mineral Oils 80
• Market Size 80
• TABLE 42 GLOBAL MINERAL OIL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 80
• Acrylic Polymers 80
• Market Size 81
• TABLE 43 GLOBAL ACRYLIC EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 81
• Other Petrochemical Materials 81
• Market Size 81
• TABLE 44 GLOBAL OTHER PETROCHEMICAL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 82
• Antimicrobials 82
• Antioxidants 82
• Dyes and Lakes 82
• TABLE 45 SYNTHETIC COLORANTS IN PHARMACEUTICALS 83
• EDTA 84
• Flavors 84
• Glycine and Glycylglycine 84
• Vinyl Polymers 84
• Silicones 85
• Miscellaneous Synthetic Petrochemicals 85
• OLEOCHEMICALS 85
• Market Size 86
• TABLE 46 GLOBAL OLEOCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 86
• TABLE 47 GLOBAL OLEOCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 86
• Fatty Alcohols 87
• Market Size 87
• TABLE 48 GLOBAL FATTY ALCOHOL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 87
• Glycerin 87
• Market Size 88
• TABLE 49 GLOBAL GLYCERIN EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 88
• Metal Stearates 88
• Market Size 88
• TABLE 50 GLOBAL METAL STEARATE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 89
• Other Oleochemicals 89
• Market Size 89
• TABLE 51 GLOBAL OTHER OLEOCHEMICAL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 89
• Natural Waxes 89
• Beeswax 90
• Candelilla Wax 90
• Carnauba Wax 90
• Cocoa and Shea Butters 90
• Lanolin 90
• Phospholipids 91
• Sodium Lauryl Sulfate 91
• Sorbitan 91
• Synthetic Glyceryl Esters 91
• Vegetable Oils 91
• PROTEINS 92
• Gelatin 92
• Market Size 92
• TABLE 52 GLOBAL PROTEINS (GELATIN) EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 93
• Albumin 93
• OTHER ORGANIC CHEMICALS 93
• TABLE 53 GLOBAL OTHER ORGANIC CHEMICAL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 94
• Alcohols 94
• Citric Acid 94
• Lactic Acid 95
• Polysaccharide Gums 95
• Shellac 95
• INORGANIC CHEMICALS 95
• MARKET SIZE 95
• TABLE 54 GLOBAL INORGANIC CHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 96
• TABLE 55 GLOBAL INORGANIC CHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 96
• CALCIUM SALTS 96
• Market Size 96
• TABLE 56 GLOBAL CALCIUM SALT EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 97
• TABLE 57 GLOBAL CALCIUM SALT EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 97
• Calcium Phosphate 97
• Market Size 98
• TABLE 58 GLOBAL CALCIUM PHOSPHATE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 98
• Calcium Carbonate 98
• Market Size 99
• TABLE 59 GLOBAL CALCIUM CARBONATE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 99
• Calcium Sulfate 99
• Market Size 99
• TABLE 60 GLOBAL CALCIUM SULFATE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 100
• HALITES 100
• Market Size 100
• TABLE 61 GLOBAL HALITE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 100
• METAL OXIDES 101
• Market Size 101
• TABLE 62 GLOBAL METAL OXIDE EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 101
• TABLE 63 GLOBAL METAL OXIDE EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 101
• Titanium Dioxide 101
• Market Size 102
• TABLE 64 GLOBAL TIO2 EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 102
• Iron Oxide 102
• Market Size 102
• TABLE 65 GLOBAL IRON OXIDE EXCIPIENT MARKET THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 103
• SILICATES 103
• Market Size 103
• TABLE 66 GLOBAL SILICATES EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 103
• TABLE 67 GLOBAL SILICATES EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 104
• Silicon Dioxide 104
• Market Size 104
• TABLE 68 GLOBAL SILICON DIOXIDE EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 105
• Talc 105
• Market Size 105
• TABLE 69 GLOBAL TALC EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 106
• Clay 106
• Market Size 106
• TABLE 70 GLOBAL CLAY EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 106
• OTHER INORGANIC CHEMICALS 107
• Market Size 107
• TABLE 71 GLOBAL OTHER INORGANIC CHEMICAL EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 107
• USP WATER (PHARMACEUTICAL WATER) 107
• MARKET SIZE 108
• TABLE 72 GLOBAL USP WATER EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS) 108
• TABLE 73 GLOBAL USP WATER EXCIPIENT MARKET, THROUGH 2014 (LBS MILLIONS) 108
• WATER FOR INJECTIONS 108
• Market Size 109
• TABLE 74 GLOBAL USP WFI EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLLIONS) 109
• PURIFIED WATER 109
• Market Size 109
• TABLE 75 GLOBAL USP PURIFIED WATER EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLLIONS) 110
• FUNCTIONAL USES 110
• TABLE 76 GLOBAL EXCIPIENT FUNCTIONAL USES MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 111
• TABLE 77 GLOBAL EXCIPIENT FUNCTIONAL USES MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 111
• FILLERS 112
• MARKET SIZE 112
• TABLE 78 GLOBAL EXCIPIENT FILLER MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 112
• TABLE 79 GLOBAL EXCIPIENT FILLER MARKET VOLUME BY TYPE, THROUGH 2014 (LBS MILLIONS) 113
• EMOLLIENTS 113
• MARKET SIZE 113
• TABLE 80 GLOBAL EMOLLIENTS EXCIPIENT MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 114
• VEHICLES 114
• MARKET SIZE 114
• TABLE 81 GLOBAL VEHICLE EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 115
• TABLE 82 GLOBAL VEHICLE EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 115
• COATINGS 116
• MARKET SIZE 116
• TABLE 83 GLOBAL COATINGS EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 116
• TABLE 84 GLOBAL COATINGS EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 117
• DISINTEGRANTS 118
• MARKET SIZE 118
• TABLE 85 GLOBAL SUPERDISINTEGRANT EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 118
• TABLE 86 GLOBAL SUPERDISINTEGRANT EXCIPIENT MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 119
• FLAVORS 119
• MARKET SIZE 119
• TABLE 87 GLOBAL FLAVORS EXCIPIENT MARKET VALUE BY TYPE, THROUGH 2014 ($ MILLIONS) 120
• TABLE 88 GLOBAL FLAVORS EXCIPIENT MARKET VOLUME BY TYPE, THROUGH 2014 (LBS MILLIONS) 120
• TABLE 89 COMPARISON OF SEVERAL SWEETENERS TO SUCROSE (%) 121
• TONICITY AGENTS 121
• MARKET SIZE 121
• TABLE 90 GLOBAL TONICITY AGENT EXCIPIENT MARKET VALUE, THROUGH 2014 ($ MILLIONS) 121
• TABLE 91 GLOBAL TONICITY AGENT EXCIPIENT MARKET VOLUME, THROUGH 2014 (LBS MILLIONS) 122
• COLORANTS 122
• MARKET SIZE 122
• TABLE 92 GLOBAL COLORANTS EXCIPIENT MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 123
• TABLE 93 GLOBAL COLORANTS EXCIPIENT MARKET VOLUME BY TYPE, THROUGH 2014 (LBS MILLIONS) 123
• OTHER FUNCTIONAL USES 123
• MARKET SIZE 123
• TABLE 94 GLOBAL MARKET FOR OTHER FUNCTIONAL USES, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 124
• PERFUMES 124
• BINDERS 124
• BUFFERS 125
• CHELATING AGENTS 125
• COMPRESSION AIDS 125
• EMULSIFIERS 125
• FOAM CONTROL AGENTS 126
• GLIDANTS 126
• HUMECTANTS 126
• LUBRICANTS 126
• PLASTICIZERS 127
• PRESERVATIVES 127
• THICKENERS 127
• DELIVERY SYSTEMS 128
• MARKET SIZE 128
• TABLE 95 GLOBAL EXCIPIENT DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 128
• TABLE 96 GLOBAL EXCIPIENT DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 129
• FIGURE 8 GLOBAL EXCIPIENT DELIVERY SYSTEMS MARKET BY TYPE, 2009 AND 2014 (%) 129
• FIGURE 8 (CONTINUED) 130
• INJECTION 130
• TABLE 97 TYPICAL INJECTION COMPOSITION (%) 130
• MARKET SIZE 131
• TABLE 98 GLOBAL EXCIPIENTS FOR INJECTIONS MARKET VALUE BY FUNCTION, THROUGH 2014 ($ MILLIONS) 131
• TABLE 99 GLOBAL EXCIPIENTS FOR INJECTIONS MARKET VOLUME BY FUNCTION, THROUGH 2014 (LBS MILLIONS) 131
• ORAL 132
• MARKET SIZE 132
• TABLE 100 GLOBAL EXCIPIENTS IN ORAL DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 133
• TABLE 101 GLOBAL EXCIPIENTS IN ORAL DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 133
• SOLIDS 133
• MARKET SIZE 133
• TABLE 102 GLOBAL EXCIPIENTS IN ORAL SOLID DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 134
• TABLE 103 GLOBAL EXCIPIENTS IN ORAL SOLID DELIVERY SYSTEMS MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 134
• TABLETS 134
• TABLE 104 TYPICAL TABLET COMPOSITION 135
• MARKET SIZE 136
• TABLE 105 GLOBAL EXCIPIENTS IN TABLETS MARKET BY FUNCTION, THROUGH 2014 ($ MILLIONS) 136
• TABLE 106 GLOBAL EXCIPIENTS IN TABLETS MARKET BY FUNCTION, THROUGH 2014 (LBS MILLIONS) 137
• Market Size (Continued) 138
• CAPSULES 139
• MARKET SIZE 139
• TABLE 107 GLOBAL EXCIPIENTS IN GELATIN CAPSULES MARKET BY TYPE, THROUGH 2014 ($ MILLIONS) 139
• TABLE 108 GLOBAL EXCIPIENTS IN GELATIN CAPSULES MARKET BY TYPE, THROUGH 2014 (LBS MILLIONS) 140
• HARD GELATIN CAPSULES 140
• TABLE 109 TYPICAL HARD GELATIN CAPSULE COMPOSITION 140
• Market Size 141
• TABLE 110 GLOBAL EXCIPIENTS IN HARD GELATIN CAPSULES MARKET VALUE BY FUNCTION, THROUGH 2014 ($ MILLIONS) 141
• TABLE 111 GLOBAL EXCIPIENTS IN HARD GELATIN CAPSULES MARKET VOLUME BY FUNCTION, THROUGH 2014 (LBS MILLIONS) 141
• SOFT GELATIN CAPSULES 142
• TABLE 112 TYPICAL SOFT GELATIN CAPSULE COMPOSITION 142
• Market Size 142
• TABLE 113 GLOBAL EXCIPIENTS IN SOFT GELATIN CAPSULES MARKET VALUE BY FUNCTION, THROUGH 2014 ($ MILLIONS) 143
• TABLE 114 GLOBAL EXCIPIENTS IN SOFT GELATIN CAPSULES MARKET VOLUME BY FUNCTION, THROUGH 2014 (LBS MILLIONS) 143
• LIQUIDS 144
• TABLE 115 TYPICAL LIQUID COMPOSITION (%) 144
• MARKET SIZE 144
• TABLE 116 GLOBAL EXCIPIENTS IN LIQUIDS MARKET VALUE BY FUNCTION, THROUGH 2014 ($ MILLIONS) 145
• TABLE 117 GLOBAL EXCIPIENTS IN LIQUIDS MARKET VOLUME BY FUNCTION, THROUGH 2014 (LBS MILLIONS) 145
• TOPICAL DELIVERY SYSTEMS 146
• MARKET SIZE 146
• TABLE 118 GLOBAL EXCIPIENTS IN TOPICAL DELIVERY SYSTEMS BY TYPE, THROUGH 2014 ($ MILLIONS) 147
• TABLE 119 GLOBAL EXCIPIENTS IN TOPICAL DELIVERY SYSTEMS BY TYPE, THROUGH 2014 (LBS MILLIONS) 147
• TABLE 120 TYPICAL OINTMENT COMPOSITION (%) 148
• CREAMS AND GELS 148
• TABLE 121 TYPICAL CREAM COMPOSITION (%) 148
• LOTIONS 149
• TABLE 122 TYPICAL TOPICAL LOTION COMPOSITION (%) 149
• DERMAL POWDERS 150
• SOLUTIONS 150
• ADVANCED DELIVERY SYSTEMS 150
• MARKET SIZE 151
• TABLE 123 GLOBAL EXCIPIENT ADVANCED DELIVERY SYSTEMS VALUE BY FUNCTION, THROUGH 2014 ($ MILLIONS) 151
• TABLE 124 GLOBAL EXCIPIENT ADVANCED DELIVERY SYSTEMS VOLUME BY FUNCTION, THROUGH 2014 (LBS MILLIONS) 151
• TABLE 124 (CONTINUED) 152
• CYCLODEXTRINS 152
• HYDROGELS 152
• IMPLANTS 152
• LIPOSOMES 152
• MICROPARTICLES 153
• MICROSPHERES 153
• NANOTECHNOLOGY (NANOPARTICLES) 153
• Nanotechnology (nanoparticles) (Continued) 154
• Nanotechnology (nanoparticles) (Continued) 155
• OSMOTIC PUMPS 156
• TRANSDERMAL 156
• TRANSMUCOSAL 157
• Buccal 157
• Tablets 157
• Capsules 158
• Lozenges 158
• Particles 159
• Thin Strips 159
• Inhalation 160
• Nasal 160
• Pulmonary 160
• Ophthalmic 161
• Otic 162
• Rectal 162
• Vaginal 163
• FINISHED PRODUCTS 163
• Market Size 163
• TABLE 125 GLOBAL EXCIPIENTS IN FINISHED PRODUCTS BY TYPE, THROUGH 2014 ($ MILLIONS) 164
• TABLE 126 GLOBAL EXCIPIENTS IN FINISHED PRODUCTS BY TYPE, THROUGH 2014 (LBS MILLIONS) 165
• PRESCRIPTION PRODUCTS 165
• MARKET SIZE 165
• TABLE 127 GLOBAL EXCIPIENTS IN RX DRUGS BY DELIVERY SYSTEM, THROUGH 2014 ($ MILLIONS) 166
• TABLE 128 GLOBAL EXCIPIENTS IN RX DRUGS BY DELIVERY SYSTEM, THROUGH 2014 (LBS MILLIONS) 166
• INJECTIONS 166
• Market Size 167
• TABLE 129 GLOBAL EXCIPIENTS IN INJECTED RX DRUGS BY TYPE, THROUGH 2014 ($ MILLIONS) 167
• TABLE 130 GLOBAL EXCIPIENTS IN INJECTED RX DRUGS BY TYPE, THROUGH 2014 (LBS MILLIONS) 167
• Small Molecule Drug Injections 167
• TABLE 131 GLOBAL EXCIPIENTS IN INJECTED RX SMALL MOLECULE DRUGS MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 168
• Biologic Drug Injections 168
• TABLE 132 GLOBAL EXCIPIENTS IN INJECTED RX BIOLOGIC DRUGS MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 169
• Protein Drugs 169
• Vaccines 170
• ORAL 170
• Market Size 170
• TABLE 133 GLOBAL EXCIPIENTS IN ORAL RX DRUGS MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 171
• TOPICAL 172
• TABLE 134 GLOBAL EXCIPIENTS IN TOPICAL RX DRUGS MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 172
• ADVANCED DRUG DELIVERY SYSTEMS 172
• TABLE 135 GLOBAL EXCIPIENTS IN ADVANCED SYSTEMS FOR RX DRUGS MARKET, THROUGH 2014 ($ MILLIONS/LBS MILLIONS) 172
• OVER-THE-COUNTER PRODUCTS 173
• MARKET SIZE 173
• TABLE 136 GLOBAL EXCIPIENTS IN OTC FINISHED PRODUCTS VALUE BY DELIVERY SYSTEM, THROUGH 2014 ($ MILLIONS) 174
• TABLE 137 GLOBAL EXCIPIENTS IN OTC FINISHED PRODUCTS VOLUME BY DELIVERY SYSTEM, THROUGH 2014 (LBS MILLIONS) 174
• FINISHED PRODUCT TRENDS 174
• PHARMACOGENOMICS 175
• COUNTERFEIT/STOLEN DRUGS 175
• INDUSTRY STRUCTURE 175
• INDUSTRY ENVIRONMENT 176
• MARKET INFLUENCES 176
• Pharmaceutical Industry Pressures 176
• General Health Trends 177
• Healthcare Industry 177
• Consumer Demographics 178
• IMPORTANT STRATEGIES 178
• R&D SPENDING 178
• CONSUMER ADVERTISING 178
• LEGISLATIVE LOBBYING 179
• CONSOLIDATION 179
• MULTIPLICITY OF DELIVERY SYSTEMS 179
• SUPPLIER LISTS 179
• QUALITY BY DESIGN 180
• MATERIAL CHOICE DECISIONS 180
• DRIVING FORCES 180
• MARKET SHARES 181
• FIGURE 9 SIMPLIFIED INDUSTRY STRUCTURE 181
• RAW MATERIAL SUPPLIERS 181
• Organic Chemical Suppliers 182
• Carbohydrate Suppliers 182
• Cellulose Suppliers 182
• FIGURE 10 MARKET SHARE OF MAJOR CELLULOSE SUPPLIERS, 2009 (%) 182
• FIGURE 10 (CONTINUED) 183
• Sugar Suppliers 183
• Actual Sugar Suppliers 183
• FIGURE 11 MARKET SHARE OF ACTUAL SUGAR EXCIPIENT SUPPLIERS, 2009 (%) 183
• FIGURE 11 (CONTINUED) 184
• Sugar Alcohols (Polyols) 184
• FIGURE 12 MARKET SHARE OF MAJOR SUGAR ALCOHOL (POLYOL) EXCIPIENT SUPPLIERS, 2009 (%) 185
• Artificial Sweeteners 185
• Starch Suppliers 186
• FIGURE 13 MARKET SHARE OF MAJOR STARCH EXCIPIENT SUPPLIERS, 2009 (%) 186
• FIGURE 13 (CONTINUED) 187
• Protein Suppliers 187
• FIGURE 14 MARKET SHARE OF MAJOR PROTEIN (GELATIN) EXCIPIENT SUPPLIERS, 2009 (%) 188
• Petrochemical Suppliers 188
• Glycol Suppliers 189
• FIGURE 15 MARKET SHARE OF MAJOR GLYCOL EXCIPIENT SUPPLIERS, 2009 (%) 189
• PVP Suppliers 190
• Mineral Hydrocarbon Suppliers 190
• Acrylic Suppliers 190
• Oleochemical Suppliers 190
• FIGURE 16 MARKET SHARE OF MAJOR OLEOCHEMICAL EXCIPIENT SUPPLIERS, 2009 (%) 191
• Inorganic Chemical Suppliers 192
• Calcium Salts Suppliers 192
• FIGURE 17 MARKET SHARE OF MAJOR CALCIUM-BASED EXCIPIENT SUPPLIERS, 2009 (%) 192
• Halite Suppliers 193
• FIGURE 18 MARKET SHARE OF MAJOR HALITE EXCIPIENT SUPPLIERS, 2009 (%) 193
• FIGURE 18 (CONTINUED) 194
• Metal Oxide Suppliers 194
• FIGURE 19 MARKET SHARE OF MAJOR METAL OXIDE EXCIPIENT SUPPLIERS, 2009 (%) 194
• FIGURE 19 (CONTINUED) 195
• Silicate Suppliers 195
• USP Water Suppliers 195
• FIGURE 20 MARKET SHARE OF MAJOR USP WATER SUPPLIERS, 2009 (%) 196
• DISTRIBUTORS/MODIFIERS 197
• Distributors 197
• TABLE 138 DISTRIBUTOR CATEGORIES 197
• Brokers 198
• Import/Export Traders 198
• Chemical Stocking/Repacking 198
• Modifiers 198
• TABLE 139 CATEGORIES OF MODIFIERS 199
• Contract Development Organizations 199
• Contract Coaters 199
• END USERS 199
• TABLE 140 CATEGORIES OF MODIFIERS 200
• Drug Companies 200
• Contract Formulators 200
• Retail and Hospital Pharmacies 201
• Pharmacy Colleges and Other Academic Institutions 201
• Other End Users 201
• INTERNATIONAL ASPECTS 202
• Americas 202
• Europe 202
• Asia/Pacific Rim 203
• Others 204

Chapter-6: COMPANY PROFILES 79

• COMPANY PROFILES 205
• COMPANY PROFILES (CONTINUED) 206
• ABBOTT LABORATORIES 207
• ADAMAS PHARMACEUTICALS, INC. 208
• ADM (ARCHER DANIELS MIDLAND CO.) 208
• AKZO NOBEL N.V. (ALSO ICI AND NATIONAL STARCH) 209
• AMERICHEM PHARMACEUTICAL CORP. 210
• AMTEX (QUIMICA AMTEX MEXICO) 210
• ARLA FOODS A.M.B.A. 211
• ASAHI KASEI CORP. (ASAHI KASEI PHARMA) 211
• ASHLAND AQUALON FUNCTIONAL INGREDIENTS (AAFI) 212
• ASSOCIATED BRITISH FOODS (ABF) 213
• BANNER PHARMACAPS, INC. 214
• BASF A.G. 215
• BAXTER INTERNATIONAL, INC. 216
• BLANVER FARMOQUIMICA, LTDA. 217
• BLUE REFERENCE 217
• BRENNTAG GROUP 218
• BUDENHEIM 218
• CABOT CORP. 219
• CALUMET SPECIALTY PRODUCTS PARTNERS, LP (PENRECO) 219
• CARGILL, INC. 220
• CHARLES TENNANT & CO., LTD. 221
• CHR. HANSEN A/S 221
• COGNIS DEUTSCHLAND GMBH & CO. K.G. 222
• COLORCON, INC. 223
• CORN PRODUCTS INTERNATIONAL, INC. 224
• COSMETIC SPECIALTIES, INC. 225
• CRISTAL GLOBAL (NATIONAL TITANIUM DIOXIDE CO., LTD.) 225
• CRODA INTERNATIONAL, PLC 225
• CRODA INTERNATIONAL, PLC (CONTINUED) 226
• CSL BEHRING, LLC 227
• CSM N.V. 227
• CTD, INC. 228
• CYDEX PHARMACEUTICALS, INC. 228
• DANISCO A/S 229
• DOW CHEMICAL CO. 230
• DOW CHEMICAL CO. (CONTINUED) 231
• DUPONT (E.I. DU PONT DE NEMOURS & CO.) 232
• EASTMAN CHEMICAL CO. 233
• EM2 SOLUTIONS, INC. 234
• EURAND 234
• EVONIK DEGUSSA GMBH (EVONIK INDUSTRIES AG) 234
• FERRO CORP. 235
• FIBROGEN, INC. 236
• FINNBRIT CONSULTING 236
• FLAVORX INC. 236
• FMC CORP. 237
• FMC CORP. (CONTINUED) 238
• FONTERRA CO-OPERATIVE GROUP, LTD. 239
• FOREMOST FARMS USA 240
• FUJI HEALTH SCIENCE, INC. (FUJI CHEMICAL INDUSTRY CO., LTD.) 241
• GATTEFOSSE GROUP 241
• GE HEALTHCARE 242
• GELITA AG 242
• GENERAL CHEMICAL (GENCHEM) 243
• GLATT GMBH (GLATT AIR TECHNIQUES, INC.) 243
• GRAIN PROCESSING CORP. 243
• GRIFOLS S.A. (LABORATORIOS GRIFOLS S.A.) 244
• GTC BIOTHERAPEUTICS, INC. 245
• HILMAR CHEESE CO. (HILMAR INGREDIENTS) 245
• HOLLANDSE MELKSUIKERFABRIEK 245
• IMERYS 246
• INTERNATIONAL SPECIALTY PRODUCTS (ISP) 246
• J.M. HUBER CORP. (CP KELCO AND HUBER ENGINEERED MATERIALS) 247
• CP KELCO 247
• HUBER ENGINEERED MATERIALS 247
• JOHNSON & JOHNSON PHARMACEUTICAL R&D 248
• JOST CHEMICAL CO. 249
• JRS PHARMA (AND J. RETTENMAIER) 249
• KEMIRA OYJ 250
• KOSTER KEUNEN HOLLAND B.V. 251
• KRAFT FOODS ATLANTIC GELATIN 251
• KRONOS WORLDWIDE, INC. 251
• LANXESS A.G. 252
• LUBRIZOL CORP. 252
• LYONDELLBASELL INDUSTRIES 252
• MALLINCKRODT BAKER, INC. (COVIDIEN) 253
• MEGGLE GMBH 254
• MERCK KGAA (AND EMD) 255
• MICRO-MACINAZIONE S.A. 256
• MINERALS TECHNOLOGIES, INC. (SPECIALTY MINERALS, INC.) 256
• MINGTAI CHEMICAL CO., LTD. 257
• MITSUBISHI CHEMICAL PERFORMANCE POLYMERS, INC. 257
• MUTCHLER, INC. PHARMACEUTICAL INGREDIENTS 258
• NITTA GELATIN, INC. 258
• NORDZUCKER AG 259
• NOVOZYMES A/S 259
• NUSIL TECHNOLOGY 260
• NUTRASWEET CO. 260
• OMYA A.G. 261
• PARAYTEC, LTD. 262
• PERRIGO CO. 262
• PFIZER, INC. 262
• P&G CHEMICALS 263
• PHARMACEUTICAL-TECHNOLOGY.COM 263
• PMC GLOBAL, INC. 263
• PURDUE PHARMA, LP 264
• QUALITY SYSTEMS DESIGN, INC. 264
• RHODIA S.A. 265
• RIO TINTO, PLC 265
• ROQUETTE FRERES 266
• ROUSSELOT S.A.S. 267
• ROYAL FRIESLANDCAMPINA N.V. 268
• R.T. VANDERBILT COMPANY, INC. 269
• RUGER CHEMICAL CO., INC. 269
• SASOL, LTD. ADR 270
• SCHERING-PLOUGH CORP. 270
• SENSIENT TECHNOLOGIES CORP. 271
• SEPPIC S.A. 271
• SHEFFIELD PHARMA INGREDIENTS 272
• SHELL CHEMICALS (ROYAL DUTCH SHELL) 273
• SHIN-ETSU CHEMICAL CO., LTD. 273
• SOLVAY S.A. 274
• SPI PHARMA, INC. 275
• STEPAN CO. 275
• STERLING BIOTECH, LTD. 276
• TABLETS & CAPSULES 276
• TAKEHARA CHEMICAL INDUSTRIAL CO., LTD. 277
• TALECRIS BIOTHERAPEUTICS, INC. 277
• TATE & LYLE, PLC 277
• TATE & LYLE, PLC (CONTINUED) 278
• TESSENDERLO GROUP (PB GELATINS) 279
• TOMITA PHARMACEUTICAL CO., LTD. 279
• UNIVAR N.V. (AND UNIVAR USA) 280
• USG CORP. 280
• VALIDATION & ENGINEERING GROUP (VEG) 280
• VERTELLUS PERFORMANCE MATERIALS, INC. (VPMI) 281
• WACKER FINE CHEMICALS (WACKER CHEMIE) 281
• WEI MING PHARMACEUTICAL MFG. CO., LTD. 282
• WEISHARDT GROUP 282
• W.R. GRACE & CO. 283