Mesenchymal Stem Cells, Advances & Applications

Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, adipocytes, beta-pancreatic islets cells, and potentially, neuronal cells.

MSCs are of intense therapeutic interest because they represent a population of cells with the potential treat a wide range of acute and degenerative diseases. MSCs are advantageous over other stem cells types for several reasons. First, they avoid the ethical issues that surround embryonic stem cell research. Second, repeated studies have found that human MSCs are immuno-privileged, and therefore, represent an advantageous cell type for allogenic transplantation, reducing the risks of rejection and complications of transplantation. Recently, there have also been significant advances in the use of autologous MSCs to regenerate human tissues, including cartilage and meniscus, tendons, and bone fractures.

This market research report focuses on recent advances in MSC research applications, explores research priorities by market segment, highlights individual labs and end-users of MSC research products, explores the competitive environment for MSC research products, and provides 5-year growth and trend analysis. Additionally, this report provides guidance for companies that offer or wish to offer competitive stem cells products to this rapidly growing, well-funded research community.

As a technology company, BioInformant employs advanced techniques and state-of-theart approaches for collecting market research data. Our standard techniques derive market data from sources that utilize high-quality primary research inputs. Our techniques are constantly updated to the changing market conditions, and may be subject to change without notification.

• Preliminary Research: Extensive secondary research based preliminary market evaluations.
• Fill-gap Research: Selectively sampled and focused primary research as a fill-gap strategy.
• Historic Analysis - Primary Product(s): Comprehensive analysis of all data for each primary product market.
• Historic Analysis - End-user Market(s): Historic analysis of all end-user industries/markets, requiring technology and market evaluations, growth projections, and market size estimation of end-user markets.
• Historic Supply Chain/Raw Materials Analysis: Comprehensive analysis of data for each primary market segment.
• Data Consolidation: Merging historic end-user market data to yield consolidated primary market data.
• Cross Linking: Primary market data (historic) is compared with resulting end-user consolidated market data and the variance in percentages between data sets is calculated by year.
• Variance Determination : A median figure for each year with a tolerance range equal to twice the variance percentage is placed. The resulting numbers are recorded.
• Projections : End-user markets are projected forward (typically 2009-2014) based upon historic growth, technology and market trends, and primary research from the market place.
• Variance Factorization : Consolidation of projected end-user market data to yield derived primary market data. The data is adjusted to the historic variance determinations, as above. The resulting data is further verified by confirmatory primary research.
• Confirmatory Primary Research : Resulting data is presented from companies or individuals participating as research partners. Variations from derived data are adjusted to reflect primary research based consensus.
• Electronically Based End-User Surveys: In addition to the methods describes above, electronically based end-user surveys are utilized. Surveys are distributed to a comprehensive panel of academic and industry representatives working within market segment(s) of interest. Statistical filtering and stratification is performed on the resulting user-response data.