Mesenchymal Stem Cells, Advances & Applications

I. Applications

• A. Basic Research Applications
  • 1. Directed Differentiation of Autologous MSCs towards Intra-Mesenchymal Lineages
  • 2. Directed Differentiation of Autologous MSCs towards Extra-Mesenchymal Lineages
• B. Supporting Hematopoietic Cells
• C. Cell-Based Therapy Applications
  • 1. Gene Transfer Applications
  • 2. Allogenic Transplantation
  • 3. Applications of MSCs for Osteochondral Repair
  • 4. Applications of MSCs for Myocardiac Repair
  • 5. Therapeutic Potential beyond Mesenchymal Lineages
• D. Use of MSC in 3-D Scaffolds for Tissue Engineering Applications

II. Application Priorities

• A. Overall
• B. By Segment
  • 1. Academic
  • 2. Biotech
  • 3. Pharma

III. Potential Labs/Customers

• A. General MSC Research Labs
• B. Osteogenic-Focused Research Labs
• C. Myogenic and Myocardial-Focused Research Labs
• D. Adipogenic-Focused Research Labs
• E. Neuronal-Focused Research Labs
• F. Immunology-Focused Research Labs
• G. Commerical Labs
• H. NIH Labs

IV. Companies Offering Human MSC Research Products, including Products Offered

• A. Stem Cell Technologies
• B. Thermo Scientific
• C. Invitrogen
• D. Celprogen
• E. ScienCell Research Laboratories
• F. Abcam
• G. BD Biosciences
• F. Millipore

V. Companies Offering Rodent MSC Research Products, including Products Offered

• A. Cell Applications
• B. Millipore
• C. Celprogen
• D. Cyagen Biosciences
• E. ScienCell Research Laboratories

VI. Projected 5-Year Market Growth

• A. Scientific Publication Trend Analysis
• B. Grant Rate Trend Analysis
• C. Patent Trend Analysis

VII. Mesenchymal Stem Cells as Tools for Drug Discovery

• A. Companies Developing Toxicology Screening Platforms for Stem Cells
• B. Advantages of Using Human MSCs for Drug Screening
• C. Potential Drug Screening Advantages of Rodent MSCs
  • 1. Acquisition, Handling, and Differentiation Advantages
  • 2. Genetic Manipulation of MSCs
  • 3. Potential for Genetically Engineered MSC Reporter Lines

VIII. Advantages of Serum Free Supplements for Use in MSC Research

IX. Research Product Opportunities and Suggestions

• A. MSCs Derived from Alternative Sources than Bone Marrow
• B. Novel RMSC Differentiation Kits
• C. Mesenchymal Stem Cell Expansion Media
• D. Mesenchymal Stem Cell Markers
• E. Mesenchymal Growth Factors
• F. Monoclonal Antibodies and Kits for Phenotyping RMSCs
• G. Chips for MicroArray Analysis of Gene Expression in RMSCs

X. Conclusions