Choices in Cord Blood Banking: Factors Influencing Parental Decision-Making

Table of Contents

PART 1: CORD BLOOD BANKING, INDUSTRY OVERVIEW

I. Abstract

II. Cord Blood Stem Cells

• A. Fetal Cord Blood Characteristics
• B. Existing Treatments
• C. Future Applications

III. Cord Blood Banking Industry

• A. History
• B. Private vs. Public Cord Blood Banks
  • 1. U.S. Public Banks
    • a. Overview
    • b. Number of Public Banks
    • c. Geographic Distribution
  • 2. U.S. Private Banks
    • a. Overview
    • b. Number of U.S. Private Banks
    • c. Geographic Distribution
  • 3. Free Programs for U.S. Families with Medical Need
  • 4. International Banks
    • a. Overview
    • b. Number Private Cord Blood Banks by International Region

IV. Market Characterization

• A. List of U.S. Private Cord Blood Banks
• B. List of U.S. Public Cord Blood Banks
• C. U.S. Mail-In Donation Cord Blood Banks
• D. Breakdown of Canadian Cord Blood Banks - Public vs. Private / AABB Accredited vs. Non-Accredited
• E. International Cord Blood Banks
  • 1. Mexican Cord Blood Banks
    • a. Private Banks
    • b. Public Banking System
  • 2. South/Central American Cord Blood Banks
    • a. Private Banks
    • b. Public Banking System
  • 3. United Kingdom Cord Blood Banks
    • a. Private Banks
    • b. Public Banking System
  • 4. European Cord Blood Banks
    • a. Private Banks
    • b. Public Banking System
  • 5. Middle Eastern Cord Blood Banks
    • a. Private Banks
    • b. Public Banking System
  • 6. Indian Cord Blood Banks
    • a. Private Banks
    • b. Public Banking System
  • 7. Asian Cord Blood Banks
    • a. Private Banks
    • b. Public Banking System
  • 8. Australian / New Zealand Cord Blood Banks
    • a. Private Australian and New Zealand Cord Blood Banks
    • b. Public Cord Blood Banks by Australian State
      • i. New South Wales
      • ii. Victoria
      • iii. Queensland
      • iv. Western Austalia, South Australia, & Tasmania
  • 9. African Cord Blood Banks
    • a. Private Banks
    • b. Public Banking System
• F. List of International Public Cord Blood Banks (Alphabetical by Country)
• G. Worldwide List of AABB Accredited Cord Blood Facilities

V. United States Cord Blood Banking Legislation

• A. U.S. State
  • 1. Washington State
  • 2. California
  • 3. Arizona
  • 4. New Mexico
  • 5. Colorado
  • 6. Texas
  • 7. Oklahoma
  • 8. Arkansas
  • 9. Louisiana
  • 10. Tennessee
  • 11. Georgia
  • 12. Illinois
  • 13. Virginia
  • 14. Maryland
  • 15. Pennsylvania
  • 16. Michigan
  • 17. Wisconsin
  • 18. New Jersey
  • 19. New York
  • 20. Massachusetts
• B. U.S. Federal
  • 1. Institute of Medicine Recommendations Study
    • a. Overview
    • b. Key Recommendations
    • c. IOM Study Shapes National Public Health Policy
  • 2. Presidential Executive Order Expanding Approved Stem Cell Lines in Ethically Responsible Ways
    • a. Background
    • b. The Order
  • 3. The Stem Cell Therapeutic and Research Act of 2005
    • a. Background
    • b. Current Status of the Act

VI. International Analysis - Trends, Policies and Industry Conditions (by Country)

• A. NORTH & SOUTH AMERICA
  • 1. Canada
  • 2. Mexico
  • 3. United States
  • 4. Brazil
  • 5. Chile
  • 6. Colombia
• B. ASIA
  • 1. China
  • 2. Japan
  • 3. Korea
  • 4. Malaysia
  • 5. Taiwan
  • 6. Singapore
  • 7. Thailand
• C. INDIA
• D. AUSTRALIA & NEW ZEALAND
• E. EUROPE
  • 1. European Union
    • a. Policy Overview
    • b. NETCORD Foundation
  • 2. France
  • 3. Germany & Austria
  • 4. Italy
  • 5. Netherlands
  • 6. Spain
  • 7. Poland
  • 8. Russian Federation
  • 9. United Kingdom

VII. Cost Analysis: Cord Blood Banking

• A. Reasons for Variation in Cord Blood Pricing
  • 1. Companies have Flexibility in the Pricing that they Set
  • 2. Companies have Variables in the Services that they Offer
  • 3. Variable Fee Breakdowns
• B. Range of Pricing for U.S. Cord Blood Companies (1-100th percentiles)
  • 1. U.S. Cord Blood Banking Price Range (1-100th%)
  • 2. Lowest U.S. Pricing
  • 3. Highest U.S. Pricing
  • 4. Average U.S. Cord Blood Costs (25-75th percentiles)
  • 5. Median Cost of U.S. Storage (50% percentile)
• C. Range of Pricing for Canadian Cord Blood Companies (1-100th percentiles)
  • 1. Canadian Cord Blood Banking Price Range (1-100th%)
  • 2. Lowest Canadian Pricing
  • 3. Highest Canadian. Pricing
  • 4. Average Canadian. Cord Blood Costs (25-75th percentiles)
  • 5. Median Cost of Canadian Storage (50% percentile)

VIII. Comparative Analysis of Quality Variables

• A. Technical Variables
  • 1. Vapor-Phase Storage vs. Liquid-Phase Storage
  • 2. Cryo-bags vs. Cryo-vials
  • 3. Pentastarch vs. Hetastarch
  • 4. Computer Controlled vs. Manual Rate Freezing
  • 5. Whole Sample vs. Volume Reduction
  • 6. High-Control vs. Low-Control Aseptic Processing
• B. Corporate Variables
  • 1. Corporate Stability
  • 2. Scientific Expertise

PART 2: EXPECTANT PARENTS, SURVEY RESULTS & FINDINGS

I. Survey Overview

• A. Survey Population
• B. Characterization of Market Survey Respondents
  • 1. Geographic Distribution of Market Survey Respondents
  • 2. Household Income Distribution of Survey Respondents
    • a. All Respondents
    • b. U.S. Respondents
  • 3. Respondent Breakdown by Race
  • 4. Respondent Breakdown by Gender
  • 5. Respondent Breakdown by Level of Education
  • 6. Respondent Breakdown by Location (City vs. Suburban vs. Rural)
  • 7. Regional Breakdown of U.S. Respondents
  • 8. Demographic Conclusions

II. Rates of Awareness: Unaware / Minimally Informed / Moderately Informed / Knowledgeable

• A. Overall
• B. By Gender
• C. By Household Income
  • 1. All Respondents
  • 2. U.S. Respondents
• D. By Education
• E. By Race
• F. By Geographic Location
  • 1. Region within U.S.
  • 2. Location (City vs. Suburban vs. Rural)
• G. By Number of Existing Children within Family (e.g. Birth Order)

III. Factors Influencing Awareness

• A. Personal Exposure: Relative Impact of Family, Co-Workers, Peers
• B. Informational Sources: Information Sites, Books Medical Pamphlets, Government Sources
• C. Medical Exposure: General Doctors, Ob / Gyn, Midwifes, Nurse, Other
• D. Promotional Sources: Internet Advertisements, Print Advertisements, Radio, TV, Other

IV. Factors Influencing Parental Decision-Making

• A. Factors Influencing the Decision Not to Store Cord Blood
  • 1. Knowledge Level
  • 2. Price Sensitivity
  • 3. Safety Concerns
  • 4. Lack of Access
  • 5. Misconceptions
• B. Factors Influencing the Decision for Private vs. Public Storage of Cord Blood
  • 1. Ethical Beliefs
  • 2. Gender
  • 3. Total Household Income
  • 4. Level of Education (Highest Level Achieved by at Least One Parent)
  • 5. Race
  • 6. Geographic Location
    • a. Region within U.S.
    • b. City vs. Suburban vs. Rural
  • 7. Access to Reliable Healthcare
  • 8. Number of Existing Children within Family (Birth Order)
  • 9. Source of Knowledge
  • 10. Perceived Support of Medical Staff
  • 11. Family Medical History
• C. International Analysis of Cord Blood Banking Perceptions (Region-by-Region)

V. Parental Responsiveness to Health Statistics

• A. Overview
• B. Health Statistics
• C. Health Statistic Conclusions

VI. Parental Expectations

• A. Quality of Services
• B. Willingness to Educate/Inform
• C. Reputability of Organization

VII. Trends

• A. Rates of Cord Blood Storage (units per year)
• B. Rates of Parental Awareness
• C. Cord Blood Research Publication Rates
• D. Cord Blood Research Funding Levels
• E. Cord Blood Patent Breakdown
• F. Rates of Cord Blood Research Product Development

VIII. Informative Websites: Online Sources Utilized by Expectant Parents

• A. Overview of Websites
  • 1. Information Only
  • 2. Commercial Affiliation
• B. Dominant Regional Websites (International Analysis)
• C. Most Important Criteria Used to Identify Sites to Inform Decision-Making
• D. Underlying Reasons for Visiting Online Resources

IX. Private Cord Blood Banking: The "Model Customer"

• A. Traits of a "Model Customer"
  • 1. "Model Customer" for a Private Cord Blood Bank
  • 2. "Model Customer" for a Public Cord Blood Bank
• B. Ideal Price Range
• C. Approaches for Communicating with Expectant Parents