Abstract
Overview
Introduction
The global incidence of STIs is estimated at several hundreds of millions
cases per year, and due to the asymptomatic nature of most infections,
underreporting is likely to mask the real incidence. Most STIs can lead to
severe sequelae, including infertility in both men and women. While bacterial
STIs can be cured, viral STIs are managed through treatment of symptomatic
disease.
Scope
- Overview of common Sexually Transmitted Infections including
epidemiological trends, risk groups and factors, disease management and R&D
focus.
- Comprehensive overviews of five common STIs, including clarification of
key issues by international opinion leaders.
- Comparative analysis of bacterial versus viral STIs in particular with
regards to disease management and goals of current therapy.
- Developmental and strategic analysis of preventative genital herpes and
HPV vaccines in late-stage clinical development.
Report Highlights
Chlamydia, one of the most common bacterial STIs, causes up to 50% of cases of
pelvic inflammatory disease (PID), a chronic infection of the female
reproductive organs. Consequences of PID are ectopic pregnancies and
infertility. Chlamydia and other STIs can further lead to severe sequelae in
men, and also in babies born to infected mothers.
Considerable evidence suggests that STIs significantly enhance the acquisition
and transmission of HIV. This is thought to be the result of biological but
also behavioral factors, notably the effect of antiretroviral therapy on the
quality of life of HIV patients. STI awareness campaigns should leverage from
the tight link between STIs and HIV.
Despite the health and economic benefits of prophylaxis for viral STIs, there
is considerable opposition to the introduction of widespread vaccination of
young girls on grounds that this might lead to early initiation of sexual
activity. Effective positioning of an STI vaccine might therefore prove a
challenging task.
Reasons to Purchase
- Understand the epidemiological drivers of five common bacterial and viral
STIs and assess the untapped patient potential offered by each.
- Elaborate successful positioning strategies for STI vaccines, taking into
consideration potential social objections to mass vaccination programs.
- Develop successful STI awareness and education campaigns by leveraging the
tight link between STIs and HIV.
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