Abstract
Overview
Introduction
In 2005, over 50.000 solid organ transplants were conducted in the seven major
markets. In order to prevent the patient's immune system from rejecting the
transplanted organ, immunosuppression therapy is required for the lifetime of
the graft with a base maintenance drug (either Calcineurin- or mTOR
inhibitors) and adjunctive therapies (antimetabolites, steroids).
Scope
- The report focuses on current and future therapies used for
immunosuppression in solid organ transplantation, with sales and volume
forecasts to 2015
- Assessment of current and future dynamics, opportunities and threats for
immunosuppressants across the seven major markets
- Overview of organ supply, national donation rates, waiting lists and
forecasts of the number of transplants and maintenance population to 2015
- Assessment of key factors affecting prescription choice, including
analysis of regional differences
Report Highlights
The transplantation market poses unusual challenges to pharmaceutical
companies, the most significant one being a lack of donor organs: the waiting
list for transplants will continue to grow faster than the number of available
organs. Another challenge is the static nature of the market: maintenance
regimens of stable patients rarely get changed.
The market for immusuppresssants used in transplantation is set to grow to
$4.3 billion by 2015s. Despite changing protocols, the leading drug class by
value should continue to be calcineurin inhibitors with a 37% market share,
followed by mTOR inhibitors
mTOR inhibitors are expected to be the fastest growing class, driven by
Wyeth's Rapamune. Datamonitor foresees the drug to gain a greater role as a
primary immunsuppressant despite current tolerability issues. Bristol Myers
Squibb's injectable fusion protein belatacept may offer another alternative to
calcineurin inhibotrs
Reasons to Purchase
- Identify and understand the dynamics in immunosuppressive protocols as
reflected in opinion leaders' thoughts
- Quantify the future immunosuppressant market size by volume and value for
each of the seven major markets
- Quantify the future market size based on transplant types, numbers and the
maintenance population
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