Abstract
Overview
Introduction
Drug targets are the critical link between drugs and their role in the
treatment of medical disorders. By grouping drug targets into key protein
families, this report provides a comprehensive analysis of the prescription
pharmaceutical market by not just molecule type and therapy area, but also by
target family.
Scope
- Classification of the specific drug targets relating to over 650 key
products across the PharmaVitae universe
- Products grouped into major target families, including GPCRs, enzymes,
extracellular signalling proteins (ECS), ion channels and nuclear receptors
- Comprehensive analysis of forecast sales to 2012 by the three fundamental
dimensions of pharma space: molecule type, therapy area and target family
- Discussion of the factors driving the variable performance of different
ATC drug classes
Report Highlights
Datamonitor has identified three fundamental dimensions that describe a
product' s position within the pharma space-molecule type, therapy area and
target type. Analysis of sales across these dimensions reveals key
attractiveness characteristics that drive performance
The target type acted on by a product dictates its standing against these key
characteristics. Products acting on ECS targets tend to rate most highly and
will outperform those acting on other target types. Conversely, products
addressing ion channels or nuclear receptors rate poorly and face an overall
decline across 2006-12
The arrival of monoclonal antibody and therapeutic protein technologies
allowed ECS targets to be exploited, expanding the ' druggable' target space
and driving sales growth across 2006-12. Beyond 2012, further technological
revolutions will, however, be required if the success experienced by these
product classes is to be repeated
Reasons to Purchase
- Identify product positioning not just in terms of molecule type and
therapy area, but also according to target family
- Rate marketed and pipeline products against the three attractiveness
characteristics that determine a product' s likelihood of commercial success
- Understand the challenges faced by different product groups depending on
the targets that they address
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