Table of Contents
- CHAPTER 1 EXECUTIVE SUMMARY
- Scope of the report
- Key findings
- CHAPTER 2 SUPPLY CHAIN OVERVIEW
- Why worry about the drug supply chain?
- The US Supply Chain
- Manufacturers wield most power in setting drug price in the US
- Wholesalers are the primary buyers for manufacturers
- Pharmacies are at the interface of the supply chain and patient
- Pharmacy Benefits Managers - a crucial link in the US supply chain
- The UK Supply Chain
- Drug list price is regulated by the PPRS
- Wholesalers compete to acquire pharmacist contracts
- The government reimburses pharmacists at list price
- Differences in drug distribution between the US and EU
- CHAPTER 3 DRUG DIVERSION
- The grey market in the US
- The illegal importation of drugs into the US
- Parallel trade in Europe
- Counterfeits enter UK via parallel trade channels
- EU focus on parallel trade and counterfeit drug link
- Strategies to tackle diversion
- Greater regulation of the pharmaceutical supply chain
- e-pedigree roll out in 2009 in California
- Drug supply restrictions are effective but can lead to domestic
shortfalls
- Dual pricing initiatives
- Tighter supply chains - direct to pharmacy distribution is gaining
traction
- GSK sets the ball rolling in the UK
- Pfizer goes further by introducing exclusive distribution
- Sanofi-Aventis and AstraZeneca introduce DTP in the UK
- Implications of the DTP scheme for the UK
- CHAPTER 4 THE SUPPLY CHAIN GOING FORWARD
- Market expansion
- Intellectual property and European Union expansion
- Drug registration
- Parallel trade in the European Union
- Parallel trade implications beyond the EU
- Manufacture outsourcing
- More complex drugs with more complex distribution needs
- The trend towards consolidation
- Wholesale industry under increasing pressure
- Infiltration of the PBM business
- Innovators fail to make PBM acquisitions a success
- CVS and Caremark merger
- Wal-Mart' s foray into pharmacy benefit management
- Growth in private label brands
- Relaxation in pharmacy outlet laws
- Differences between US versus EU distribution
- US retailers leave wholesalers with little net margin
- US manufacturers subsidize distribution
- European retailers have less power
- CHAPTER 5 BIBLIOGRAPHY
- Publications and online articles
- Datamonitor resources
- APPENDIX
- Abbreviations
- Exchange rates
- List of Tables
- Table 1: Exchange rates, 2007
- List of Figures
- Figure 1: Drug and monetary flow in the US supply chain
- Figure 2: The UK pharmaceutical supply chain
- Figure 3: UK retail pharmacies, 2006
- Figure 4: US pharmaceutical grey market
- Figure 5: Drivers and strategies to tackle, drug diversion
- Figure 6: UK pharmaceutical distribution channels
- Figure 7: Expansion of wholesaler services
- Figure 8: Factors impacting on the future drug supply chain
- Figure 9: Consolidation within the supply chain
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