Abstract
The area of protein-protein interaction has been growing at a tremendous rate. The market is
expected to reach over $50 billion by year 2010. Protein-protein interaction targeting activities
are increasing and are expected to bring success in the near future. Protein-protein interactions
are critical for normal and tumor cells signal transduction pathways, making them attractive targets
for developing therapeutic molecules.Targeting protein-protein interactions has been challenging due
to the diversity and complexity of proteins involved and the structures they form. However, the
number of therapeutic molecules that have been developed against signal transduction proteins that
are involved in protein-protein interactions is increasing at a steady rate. |