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ADME is the key for ensuring efficacy and tolerability. However, many drugs still fail due to poor ADME. This report examines the latest research on the causes and consequences of ADME changes in the elderly and children.
Commercial considerations such as market size, demographics, and the impact of ADME on the cost of drug development are thoroughly discussed. In addition, age related changes in ADME and in silico ADME profiles are detailed. The Report features exclusive interviews with key opinion leaders in the ADME arena as well as relevant case studies. |