SPECIAL REPORT: Can Innovation Supplant Convention in Sarcoidosis Treatment?

Table of Contents

• Executive Summary
  • Strategic Considerations
  • Stakeholder Implications
• Introduction
• Overview of Sarcoidosis
  • Symptoms
  • Pathophysiology and Etiology
  • Diagnosis
• Epidemiology
  • Overview
  • Disease Defi nition
  • Methods
  • Subpopulations
• Current Therapies
  • Corticosteroids
  • Methotrexate
  • Antimalarials
  • TNF-Alpha Inhibitors
  • Other Treatments
• Emerging Therapies
  • Academic Research
  • Agents Seeking Approval for Sarcoidosis: Celgene' s Apremilast, Centocor/Medarex' s Stelara, and MondoBiotech/Biogen Idec' s Aviptadil
• Outlook
• Bibliography

Tables

• 1. The Scadding Criteria for Sarcoidosis Staging
• 2. Current Therapies Used in the Treatment of Sarcoidosis
• 3. Academic and Government-Initiated Clinical Trials in Sarcoidosis
• 4. Agents in Development for the Treatment of Sarcoidosis
• 5. Sales of Agents to Treat Sarcoidosis in the United States, 2008

Figures

• 1. Granuloma Formation in Sarcoidosis
• 2. Diagnosed Incidence of Sarcoidosis in the United States, 2008-2018