Impact of Inhaled Insulin on the Insulin Market

Table of Contents

• Executive Summary
• Strategic Considerations
• Stakeholder Implications
• Introduction
• Overview of Insulin Therapy
• Mechanism of Action
• Types of Manufactured Insulin
• Long-Acting Insulins
• Intermediate-Acting Insulins
• Short-Acting Insulins
• Drug Delivery
• Use of Insulin in the Treatment of Diabetes
• Type 1 Diabetes
• Type 2 Diabetes
• The Insulin Market, 2005
• Exubera
• How Exubera Works
• Development History
• Clinical Trials
• How Important Is Exubera to Pfizer?
• Other Inhaled Insulins in Development
• Eli Lilly and Alkermes' AIR Inhaled Insulin System
• Novo Nordisk and Aradigm' s AERx-iDMS System
• MannKind' s Technosphere
• The Outlook for Inhaled Insulins

Tables

• 1. Top-Selling Insulin Products, 2005
• 2. Pfizer' s Top-Selling Products in 2005 and Their Patent Expiries
• 3. Inhaled Insulins in Development

Figures

• 1. Growth of the Insulin and Antidiabetic Markets, 1995-2005
• 2. Expansion of Sales of Insulin Analogues, 2000-2005
• 3. Pfizer' s Pharmaceutical Sales, 2000-2005