Target Product Profiles: Physician Insights on Key Attributes: Hypertension - An oral drug that reduces left ventricular mass index significantly more than valsartan

Table of Contents

• Introduction
  • Using Target Product Profi les in Your Market Strategy
  • Report Contents
  • Target Product Profi le Methodology
• Etiology and Pathophysiology
  • Overview
  • Blood Pressure Regulation
    • The Sympathetic Nervous System
    • The Renin-Angiotensin-Aldosterone System
    • Natriuresis
    • The Potential Role of the Endothelin System in the Pathogenesis of Hypertension
  • Pathophysiology
    • The Hypertensive State
    • Sustained Endothelial Dysfunction
    • Hypercoagulability
    • Arterial Stiffness
    • Uncomplicated and Complicated Hypertension
    • Hypertension and Cardiovascular Risk
  • Etiology
    • Causes of Hypertension
    • Nonmodifi able Risk Factors
    • Modifi able Risk Factors
• Target Product Profi le Discussion-Hypertension
  • Target Product Profi le Summary for Hypertension-2011
  • Assessing Drug Development Opportunities
  • Physician Survey Results
    • Effi cacy
    • Safety and Tolerability
    • Delivery
    • Estimated Patient Share
  • Pricing Potential
  • Forecasted 2016 Pricing Environment
  • Competitors to Watch
  • Emerging Product Profi les