Target Product Profiles: Physician Insights on Key Attributes - Crohn's Disease, A parenterally dosed therapy that induces closure and healing of fistulas in a greater percentage of Crohn's disease patients than infliximab does.

Table of Contents

• Introduction
  • Using Target Product Profi les in Your Market Strategy
  • Report Contents
  • Target Product Profi le Methodology
• Etiology and Pathophysiology
  • Overview
  • Etiology
    • The Immune Response
    • Microbial Involvement
    • The Infl ammatory Cascade
    • Cytokines
    • Lipid Mediators
    • Cell Adhesion Molecules
    • Mitogen-Activated Protein Kinases
    • Downregulation of the T-Cell Response
    • Genetics
    • Risk Factors
  • Pathophysiology
    • Location and Extent of GI Tract Involvement
    • Complications of Crohn' s Disease
• Target Product Profi le Discussion-Crohn' s Disease
  • Target Product Profi le Summary for Crohn' s Disease-2011
  • Assessing Drug Development Opportunities
  • Physician Survey Results
    • Effi cacy
    • Safety and Tolerability
    • Delivery
    • Estimated Patient Share
  • Pricing Potential
  • Forecasted 2016 Pricing Environment
  • Competitors to Watch
  • Emerging Product Profi le .