Abstract
Introduction
Although the obsessive-compulsive disorder (OCD) market is small and OCD
diagnosis rates are low, this market is characterized by substantial unmet
need and commercial opportunity. Companies looking to expand their agents into
this market need to explore unconventional strategies that will minimize the
resources necessary to ensure success in OCD.
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- Despite the high use of drug therapy in the treatment of OCD, 40-60% of
patients do not achieve suffi cient relief from their symptoms. What
opportunities does this unmet need present to developers? Are any agents now
in development likely to meet this need?
- Due to the large percentage of patients who are not suffi ciently treated
with available approved agents, psychiatrists often prescribe off-label agents
to treat OCD. How well do these off-label agents perform in the OCD market?
Will pending guidance from the FDA regarding the distribution of data from
clinical trials in off-label indications help companies increase their market
share for off-label treatments?
- Although there are few agents in commercial development for OCD, there are
agents being investigated for their effi cacy in OCD by research and medical
organizations. What does the possible infl ux of a large number of new
agents to treat OCD mean for currently available treatments? How can emerging
agents differentiate themselves from other current and emerging agents?
Scope
- Overview of OCD: symptoms and diagnosis, etiology.
- Epidemiology: Decision Resources estimates of the number of
prevalent cases of OCD in the major markets over 2007-2017 and the number of
diagnosed and drug-treated cases in the major markets in 2007.
- Treatment algorithms: a treatment decision tree, a listing of
currently used agents, and profi les of leading agents.
- Use of off-label agents: discussion of agents commonly used
off-label, physician attitudes toward off-label use, pending FDA proposals to
broaden marketing of these agents.
- OCD market: 2007 sales fi gures, current market dynamics,
strategies for maximizing market potential.
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