Table of Contents
- Executive Summary
- Strategic Considerations
- Stakeholder Implications
- Introduction
- Overview of Generalized Anxiety Disorder
- Disease Defi nition
- Diagnosis
- Pathophysiology of Generalized Anxiety Disorder
- Serotonin
- Norepinephrine
- Gamma-Aminobutyric Acid
- Glutamate
- Corticotropin-Releasing Factor
- Substance P
- Prevalence of Generalized Anxiety Disorder
- Current Therapies for Generalized Anxiety Disorder
- Selective Serotonin Reuptake Inhibitors
- Serotonin and Norepinephrine Reuptake Inhibitors
- Benzodiazepines
- Emerging Therapies for Generalized Anxiety Disorder
- Sanofi -Aventis' s Saredutant
- Takeda/Lundbeck' s Lu AA21004
- Pfi zer' s Lyrica and PD-332334
- Synosia Therapeutics' Rufi namide
- Sepracor' s SEP-225441
- Generalized Anxiety Disorder Market: 2007 Statistics and Future Outlook
Tables
- 1. Common Symptoms of Generalized Anxiety Disorder
- 2. Common Risk Factors for Generalized Anxiety Disorder
- 3. Therapies Commonly Used to Treat Generalized Anxiety Disorder
- 4. Agents in Development to Treat Generalized Anxiety Disorder
- 5. Sales of Agents to Treat Generalized Anxiety Disorder, 2007
Figures
- 1. Structures of the Brain Implicated in Anxiety Disorders
- 2. Prevalent Cases of Generalized Anxiety Disorder in the Major
Pharmaceutical Markets, 2007 and 2012
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