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Table of Contents
INTRODUCTION 5
- BIOTECHNOLOGY DEFINED 5
- TISSUE CULTURE 6
- CELL FUSION 8
- EMBRYO TRANSFER 9
- RECOMBINANT DNA TECHNOLOGY 9
APPLICATIONS OF BIOTECHNOLOGY 10
- HEALTHCARE 10
- AGRICULTURAL BIOTECHNOLOGY 13
THE HUMAN GENOME PROJECT (HGP) 14
- GOALS OF THE HUMAN GENOME PROJECT 15
- BENEFITS OF THE HUMAN GENOME PROJECT 17
GENOMICS 19
ROLE OF IT 20
- DATA MANAGEMENT 24
- EXPERIMENTATION, SIMULATION AND INFORMATION 25
- RESEARCH EFFICIENCY 26
INFORMATICS 27
- DEFINITION & ROLE OF BIOINFORMATICS 27
- TYPES OF DATA AND BIOINFORMATICS APPLICATIONS 33
- HISTORICAL PERSPECTIVE 34
- CURRENT STATE 36
- FUNCTIONS OF INFORMATICS SOFTWARE 36
INDUSTRY CHARACTERISTICS 37
- TARGET MARKETS FOR INFORMATICS SOFTWARE 37
- STEPS INVOLVED IN BRINGING A DRUG TO MARKET 38
- COSTS INCURRED IN DEVELOPING A NEW DRUG 39
- INDUSTRY DRIVERS AND CHALLENGES 41
- INDUSTRY RISKS 44
PRODUCTS, PROCESSES & TOOLS OF BIOINFORMATICS 49
- PRODUCTS OF BIOINFORMATICS 49
- BIOINFORMATICS PROCESSES 50
- INFORMATICS TOOLS AND FUNCTIONALITIES 50
ROLE OF BIOINFORMATICS IN THE BIOTECHNOLOGY VALUE CHAIN 51
BIOINFORMATICS MARKET SEGMENTS 52
- DATABASE 52
- HARDWARE 52
- SOFTWARE 52
- BIOINFORMATICS SERVICES 53
BIOINFORMATICS MARKET SIZE 54
- METHODOLOGY 55
- SALES AND R&D 55
- IT BUDGET 56
- PROJECTED BIOINFORMATICS MARKET SIZE 57
- BIOINFORMATICS MARKET BREAK-UP 58
BIOINFORMATICS BUSINESS MODELS 59
- CHANGING BUSINESS MODELS 61
COMPETITION FOR PURE PLAY INFORMATICS FIRMS 63
- NONPROFIT ORGANIZATIONS 63
- IN-HOUSE BIOINFORMATICS SOLUTIONS 63
- LARGE IT COMPANIES 64
BIOINFORMATICS TARGET SCIENTIFIC DISCIPLINES 65
- COMPARATIVE GENOMICS 65
- PHARMACOGENOMICS 66
- FUNCTIONAL GENOMICS 66
- PROTEOMICS 67
- STRUCTURAL GENOMICS 69
- IMAGE INFORMATICS 70
- CLINICAL TRIAL INFORMATICS 70
BIOINFORMATICS ARCHITECTURE 71
BIOINFORMATICS APPLICATIONS 73
- DATA SEARCH TOOLS 73
- DATA VISUALIZATION TOOLS 73
- DATA MINING AND CLUSTERING APPLICATIONS 73
- ENTERPRISE SOLUTIONS 74
- DATAWAREHOUSING 74
EVALUATION OF BIOINFORMATIC SOLUTIONS 74
- REQUIREMENTS STUDY 75
- SHORTLISTING THE OPTIONS 75
- SCORING PATTERNS 75
- PERFORMANCE 78
DATA STORAGE 78
- DATA MANAGEMENT IN DRUG DISCOVERY 79
- KEY ISSUES IN BIOINFORMATICS STORAGE 80
CONVERGENCE OF INDUSTRIES 80
- PROTEINS AS A DRIVER 82
- BIOTECH ALLIANCES 84
CURRENT BIOINFORMATICS RESEARCH 84
- PATENTING BIOINFORMATICS ALGORITHMS 85
CURRENT STATE OF THE INDUSTRY 85
THE FUTURE 87
- TRENDS FOR THE FUTURE 88
- KEY APPLICATIONS OF THE FUTURE 89
Vendor Profiles
- 1. 3RD MILLENIUM INC. (WWW.3RDMIL.COM)
- 2. ACCELRYS (WWW.ACCELRYS.COM)
- 3. ACLARA (WWW.ACLARA.COM)
- 4. AGILENT TECHNOLOGIES (WWW.AGILENT.COM)
- 5. ALGONOMICS (WWW.ALGONOMICS.COM)
- 6. AFFYMETRIX (WWW.AFFYMETRIX.COM)
- 7. ALKAMI BIOSYSTEMS (WWW.ALKAMI.COM)
- 8. ANVIL (WWW.ANVILINFORMATICS.COM)
- 9. BIODISCOVERY (WWW.BIODISCOVERY.COM)
- 10. BIOINFORMATICS SOLUTIONS (WWW.BIOINFORMATICSSOLUTIONS.COM)
- 11. BIOSENTIENTS (WWW.BIOSENTIENTS.COM)
- 12. BIOTOOLS INC. (WWW.BIOTOOLS.COM)
- 13. BLACKSTONE COMPUTING (WWW.BLACKSTONECOMPUTING.COM)
- 14. CELERA (WWW.CELERA.COM)
- 15. COMPUGEN (WWW.CGEN.COM)
- 16. CURAGEN (WWW.CURAGEN.COM)
- 17. DECODON (WWW.DECODON.COM)
- 18. DISCOVERY PARTNERS INTERNATIONAL (WWW.DISCOVERYPARTNERS.COM)
- 19. GENEDATA (WWW.GENEDATA.COM)
- 20. GENE LOGIC (WWW.GENELOGIC.COM)
- 21. GENODYSSEE (WWW.GENODYSSE.COM)
- 22. GENOMICS COLLABORATIVE (WWW.GENOMICSINC.COM)
- 23. GENOMIC SOLUTIONS (WWW.GENOMICSOLUTIONS.COM)
- 24. GEOSPIZA (WWW.GEOSPIZA.COM)
- 25. IMAGING RESEARCH (WWW.IMAGINGRESEARCH.COM)
- 26. INCYTE (WWW.INCYTE.COM)
- 27. INFORMAX (WWW.INFORMAXINC.COM)
- 28. KSHEMA TECHNOLOGIES (WWW.KSHEMA.COM)
- 29. LABSTREAM (WWW.LABSTREAM.COM)
- 30. LION BIOSCIENCE (WWW.LIONBIOSCIENCE.COM)
- 31. MOLECULAR MINING (WWW.MOLECULARMINING.COM)
- 32. NEXUS GENOMICS (WWW.NEXUSGENOMICS.COM)
- 33. PARACEL (WWW.PARACEL.COM)
- 34. PARTEK (WWW.PARTEK.COM)
- 35. ROSETTA INPHARMICS (WWW.RII.COM)
- 36. SILCON GENETICS (WWW.SILICONGENETICS.COM)
- 37. SPOTFIRE (WWW.SPOTFIRE.COM)
- 38. STRAND GENOMICS PVT. LTD. (WWW.STRANDGENOMICS.COM)
- 39. STRUCTURAL BIOINFORMATICS INC. (WWW.STRUBIX.COM)
- 40. THIRD WAVE TECHNOLOGIES (WWW.TWT.COM)
- 41. TIMELOGIC (WWW.TIMELOGIC.COM)
- 42. TRIPOS (WWW.TRIPOS.COM)
- 43. TURBOGENOMICS (WWW.TURBOGENOMICS.COM)
List of Figures
- Figure 1: Venture Capital Investments in biotechnology
- Figure 2: Number of Venture Capital deals in biotechnology
- Figure 3: Equity investments in biotechnology during year 2001
- Figure 4: Informatics applications along the drug discovery value chain
- Figure 5: Bioinformatics software functionalities
- Figure 6: Growth of GenBank
- Figure 7: EMBL Database Growth
- Figure 8: Steps involved in bringing a drug to market
- Figure 9: Break up of the total costs in developing a new drug ($ US Million)
- Figure 10: Role of Bioinformatics in the biotechnology value chain
- Figure 11: Worldwide projected sales and R&D Expenditure ($ US Billion)
- Figure 12: Worldwide projected growth in IT Budget ($ US Billion)
- Figure 13: Worldwide projected Bioinformatics market ($ US Billion)
- Figure 14: Worldwide Bioinformatics market break-up ($ US Billion)
- Figure 15: Steps of a Proteomics experiment
- Figure 16: Bioinformatics Architecture
List of Tables
- Table 1: Leading Biotechnology companies
- Table 2: Data source and Bioinformatic Investigations
- Table 3: Drivers and challenges of the Bioinformatics industry
- Table 4: Bioinformatics courses on offer
- Table 5: Web based Bioinformatics courses on offer
- Table 6 - Bioinformatics activities, sub activities and key players
- Table 7: Alliances between IT/Telecom and Biotechnology firms
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