Smith & Nephew Medical Devices Company Intelligence Report

Table of Contents

• EXECUTIVE SUMMARY
• OVERVIEW
• Recent Key Events
• Financial Results
• Revenue by Division, 2004-2006 (US$ million)
• Fig.1: Percentage of Revenue by Division, 2006
• STRATEGIC FOCUS
• Reconstruction
• Plus Orthopedics Holding Acquisition
• Trauma & Clinical Therapies
• Endoscopy
• Advanced Wound Management
• PRODUCT PORTFOLIO AND R&D
• Fig.2: Global Orthopaedic Market Shares, 2006
• RECONSTRUCTION PRODUCTS
• Operating Results - Reconstruction Division, 2005-2006 (US$ million)
• Fig.3: Reconstruction Division - Sales by Product Type, 2006
• Fig.4: Reconstruction Division - Sales by Region, 2006
• Market Dynamics
• Fig.5: Global Reconstruction Market Shares, 2006
• Fig.6: Global Reconstruction Market by Product, 2006
• Key Products and Technologies
• Recent Product Approvals
• Computer-Assisted Surgery
• AchieveCAS
• BrainLAB Products
• iON IntraOperative Navigation System
• Knee Products
• Journey Deuce Knee
• Journey Bi-Cruciate Stabilized Knee System
• Legion Revision Knee System
• Genesis II Knee System
• Profix Total Knee System
• Hip Implant Products
• Birmingham Hip Resurfacing System
• BHR Survivorship Results*
• Emperion Modular Hip System
• Anthology Hip Stem
• Synergy Hip System
• Spectron Total Hip System
• Reflection Ceramic Acetabular System
• Shoulder Systems
• Cements and Accessories
• TRAUMA AND CLINICAL THERAPIES DIVISION
• Operating Results - Trauma & Clinical Therapies, 2005-2006 (US$ million)
• Fig.7: Trauma & Clinical Therapies - Sales by Product, 2006
• Fig.8: Trauma & Clinical Therapies - Sales by Region, 2006
• Fig.9: Trauma & Clinical Therapies Market, US$4.6 billion, 2006*
• Recent Product Approvals
• Trauma Products
• Fig.10: Global Fixation Market, 2006*
• Internal Fixation Products
• TriGen Intramedullary Nail System
• Peri-Loc Periarticular Locked Plating System
• Intramedullary Hip Screw (IMHS)
• IMHS CP
• Asian IMHS
• External Fixation
• JET-X Unilateral Fixator
• Taylor Spatial Frame Fixator
• Ilizarov External Fixator
• Osteobiologics
• Clinical Therapies
• Joint Fluid Therapy Products
• Durolane
• Supartz Joint Fluid Therapy
• Bone Repair Stimulation Market
• Exogen Bone Healing System
• Spine Products
• Intradiscal ElectroThermal (IDET) Procedure and the SpineCATH Catheter
• Controlled Disc Stimulation (CDS) System
• Electrothermal 20S Spine System
• Acutherm Decompression Catheter
• ENDOSCOPY
• Operating Results - Endoscopy Division, 2005-2006 (US$ million)
• Fig.11: Endoscopy Division - Sales by Region, 2006
• Fig.12: Endoscopy Division - Sales by Product Type, 2006
• Recent Product Approvals
• Key Arthroscopy Products
• Fig.13: Global Arthroscopy Market (US$2 billion), 2006*
• Acufex Hand-Held Instrumentation
• Dyonics Arthropak Procedure Kits
• Bioraptor Suture Anchor
• Hip Products
• Lateral Hip Distractor
• Hip Positioning System
• Knee Products
• OsteoBiologics' TruFit Products
• Calaxo Osteoconductive Interference Screw
• GTS System
• FasT-Fix Meniscal Repair System
• Shoulder Arthroscopy
• Kinsa Suture Anchor
• Accu-Pass Suture Shuttle
• Radiofrequency Devices
• S&N ElectroThermal Arthroscopy System
• Dyonics Series 9000 ElectroBlade Resector
• Dyonics Powered Instruments
• Access/Fluid Management Systems
• Vascular Products
• TriVex System
• Visualisation/Image Management
• Digital OR and the Condor Control System
• 660HD Image Management System
• SV420 Camera Series
• ADVANCED WOUND MANAGEMENT
• Operating Results - Advanced Wound Management, 2005-2006 (US$ million)
• Fig.14: Advanced Wound Management Sales by Region, 2006
• Fig.15: Advanced Wound Management Sales by Product, 2006
• Wound Care Market
• Fig.16: Global Wound Care Market, 2005-2006 (US$ billion)*
• Wound Care Market by Product, 2005-2011 (US$ million)*
• Leading Advanced Wound Care Manufacturers' Sales and Market Shares, 2006
• Fig.17: Global Advanced Wound Care Market (US$4.1 billion), 2006*
• Key Products
• Recent Product Approvals
• Biobrane Biosynthetic Wound Dressing
• VersaJet Hydrosurgery System
• Allevyn Hydrocellular (Foam) Dressings
• Allevyn Non-Adhesive
• Allevyn Adhesive and Allevyn Sacrum
• Iodosorb/Iodoflex Infection Management Products
• Cadesorb PH-Modulating Ointment
• Acticoat Antimicrobial Dressings
• Melolin Low Adherent Dressings
• IV3000 IV Dressings
• Primapore
• Catrix Wound Dressing
• RESEARCH AND DEVELOPMENT
• Research Establishments
• S&N Research Centre
• Research Projects
• Cross-Business Research Programmes
• Biomaterials
• Cell-based Therapies
• Orthopaedics Research Programme
• Endoscopy Research Programmes
• Advanced Wound Management
• Research Agreements
• Q-Med
• Alexandria Research Technologies
• Helix BioMedix
• GE Healthcare
• INTERNATIONAL ACTIVITIES
• Revenue by Location of Customer, 2004-2006 (US$ million)
• Revenue by Geographic Origin, 2004-2006 (US$ million)
• Assets by Geographic Region, 2004-2006 (US$ million)
• Fig.18: Percentage of Revenue by Location of Customer, 2006
• Fig.19: Percentage of Revenue by Geographic Origin, 2006*
• Fig.20: Percentage of Assets by Geographic Region, 2006*
• Fig.21: S&N and Plus Orthopedics - Combined Pro Forma Sales by Region, 2006*
• UNITED KINGDOM
• UNITED STATES
• Endoscopy
• Reconstruction and Trauma & Clinical Therapies
• Wound Management
• CONTINENTAL EUROPE
• Spain
• Switzerland
• ASIA
• Japan
• Major Manufacturing Locations
• APPENDICES
• APPENDIX 1 - FINANCIAL INDICATORS
• APPENDIX 2 - KEY CORPORATE EVENTS
• APPENDIX 3 - MERGERS AND ACQUISITIONS
• Key Mergers & Acquisitions
• Plus Orthopedics Holding
• OsteoBiologics
• Leading Medical
• Midland Medical Technologies
• Reed Medical Designs
• Versajet Surgical Debridement Product
• Advanced Tissue Sciences' Assets
• Oratec Interventions
• Instrument Makar
• Westaim Biomedical' s Burns Dressing Business
• Beiersdorf' s Advanced Woundcare Business
• Orthopaedic Biosystems
• 3M' s Orthopaedic Implant Business
• Exogen
• Exu-Dry
• Perstorp Wound Care Products
• Medizintechnik Konrad Ludi
• Acufex Microsurgical' s American Home Products
• Basel SpA
• APPENDIX 4 - DIVESTITURES
• Tissue Engineering Products
• BSN Medical
• AbilityOne Products
• Rehabilitation Business
• ENT Business
• Female Hygiene and Toiletries Division
• First Aid Dressings Business
• Bracing and Support Systems Business
• Spinal Product Line
• Perry
• Southalls Hygiene Washroom Servicing Operations
• Ditropan Incontinence Drug
• Ioptex Research
• Nivea Toiletries
• SoloPak
• Equipment and Plastics Divisions
• APPENDIX 5 - AGREEMENTS
• Key Agreements
• Covalon Technologies
• UDL Laboratories
• Movianto Deutschland
• Nexa Orthopedics
• Lescarden
• Q-Med
• Derma Sciences
• ArthroCare
• PhDx Systems
• Orthocrat
• ORTHOsoft
• Tenet Medical Engineering
• Osteotech
• Finsbury Orthopaedics
• Lumitex
• BrainLAB
• Medtronic
• IsoTis
• Nucryst Pharmaceuticals (Westaim Biomedical)
• BTG
• Seikagaku
• Kurgan All Union Scientific Centre for Restorative Traumatology and Orthopaedics
• Advanced Medical Solutions
• Supply Agreements
• Novation
• Kaiser Permanente
• Amerinet
• Termination of Agreement
• HealthPoint
• APPENDIX 6 - LITIGATION
• Synthes
• US Subpoenas
• Arthrotek
• Arthronet GmbH & Co KG
• ArthroCare
• Macrotextured Oxinium Femoral Knee Components

Index of Tables

• Recent Key Events
• Revenue by Division, 2004-2006 (US$ million)
• Operating Results - Reconstruction Division, 2005-2006 (US$ million)
• Recent Product Approvals
• BHR Survivorship Results*
• Operating Results - Trauma & Clinical Therapies, 2005-2006 (US$ million)
• Recent Product Approvals
• Operating Results - Endoscopy Division, 2005-2006 (US$ million)
• Recent Product Approvals
• Operating Results - Advanced Wound Management, 2005-2006 (US$ million)
• Wound Care Market by Product, 2005-2011 (US$ million)*
• Leading Advanced Wound Care Manufacturers' Sales and Market Shares, 2006
• Recent Product Approvals
• Revenue by Location of Customer, 2004-2006 (US$ million)
• Revenue by Geographic Origin, 2004-2006 (US$ million)
• Assets by Geographic Region, 2004-2006 (US$ million)
• Major Manufacturing Locations
• Key Mergers & Acquisitions
• Key Agreements

Index of Charts

• Fig.1: Percentage of Revenue by Division, 2006
• Fig.2: Global Orthopaedic Market Shares, 2006
• Fig.3: Reconstruction Division - Sales by Product Type, 2006
• Fig.4: Reconstruction Division - Sales by Region, 2006
• Fig.5: Global Reconstruction Market Shares, 2006
• Fig.6: Global Reconstruction Market by Product, 2006
• Fig.7: Trauma & Clinical Therapies - Sales by Product, 2006
• Fig.8: Trauma & Clinical Therapies - Sales by Region, 2006
• Fig.9: Trauma & Clinical Therapies Market, US$4.6 billion, 2006*
• Fig.10: Global Fixation Market, 2006*
• Fig.11: Endoscopy Division - Sales by Region, 2006
• Fig.12: Endoscopy Division - Sales by Product Type, 2006
• Fig.13: Global Arthroscopy Market (US$2 billion), 2006*
• Fig.14: Advanced Wound Management Sales by Region, 2006
• Fig.15: Advanced Wound Management Sales by Product, 2006
• Fig.16: Global Wound Care Market, 2005-2006 (US$ billion)*
• Fig.17: Global Advanced Wound Care Market (US$4.1 billion), 2006*
• Fig.18: Percentage of Revenue by Location of Customer, 2006
• Fig.19: Percentage of Revenue by Geographic Origin, 2006*
• Fig.20: Percentage of Assets by Geographic Region, 2006*
• Fig.21: S&N and Plus Orthopedics - Combined Pro Forma Sales by Region, 2006*