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Market Research Report
Drug Delivery Technologies: Players, products & prospects to 2018
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Table of Contents
REPORT OVERVIEW
- Controlled-Release Delivery Technologies
- Nano-enabled Delivery Technologies
- Nucleic Acid Delivery Technologies
- Targeted Delivery Technologies
- Competitor Ratio Analysis Summary
DRUG DELIVERY TECHNOLOGIES: CONTROLLED-RELEASE
- EXECUTIVE SUMMARY
- INTRODUCTION
- Overview of controlled-release delivery: past, present & future
- Leading controlled-release technology platforms & characteristics
- Controlled delivery profiles
- Controlled-release delivery: motivators & resistors
- Motivators
- Controlled-Release technology motivators
- Resistors
- Controlled-Release technology resistors
- Controlled-release delivery: impact on product lifecycles
- Impact of reformulation on product life-cycle
- CONTROLLE D-RELE ASE DELIVE RY
- Types of controlled-release delivery used by pharma industry
- Activated controlled-release delivery
- Activated controlled-release delivery - ALZA' s OROS systems
- Degradation controlled-release delivery
- Degradation controlled-release delivery - SkyePharma' s GEOMATRIX
- Diffusion controlled-release delivery
- Monolithic diffusion controlled-release delivery - LaboPharm' s Contramid
- Reservoir diffusion controlled-release delivery - Impax' CMDS
- Combined controlled-release delivery - Flamel' s Micropump
- Advantages and disadvantages of controlled-release platforms
- Current therapeutic application of controlled-release in drug delivery
- Leading brands that utilise controlled-release delivery
- Leading controlled-release approved drugs
- Future commercial applications & opportunities
- STRATEGIE S OF DRUG DELIVE RY COMPANIE S
- Leading controlled-release drug delivery companies
- Leading controlled-release drug delivery companies
- Partnerships & acquisitions
- Strategic developmental & commercialisation partnerships
- Merger & acquisitions
- Recent partnerships & acquisitions in the controlled-release field
- Intellectual Property
- Controlled-Release patents
- THE CONTROLLED - RELEASE MARKET
- Now 2009
- Approved controlled-release product sales
- Future 2018
- Global controlled-release product sales
- Novel controlled-release product sales
- COMPETITOR ANALYSIS
- Movers & Shakers: Cutting edge or losing their grip
- Movers & shakers in controlled-release drug delivery systems
- COMPANY PROFILES
- AlphaRx Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- AlphaRx' product pipeline
- Sales forecasts of products utilising the delivery technology
- AlphaRx' drug delivery sales
- Competitor Ratio Analysis
- ALZA Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- ALZA' s product pipeline
- Sales forecasts of products utilising the delivery technology
- ALZA' s drug delivery sales
- Competitor Ratio Analysis
- Antares Pharma, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Antares' product pipeline
- Sales forecasts of products utilising the delivery technology
- Antares' drug delivery sales
- Competitor Ratio Analysis
- Biovail Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Biovail' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Biovail' s drug delivery sales
- Competitor Ratio Analysis
- Camurus AB
- Proprietary delivery technology
- Camurus' FluidCrystal CR technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Camurus AB' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Camurus AB' s drug delivery sales
- Competitor Ratio Analysis
- Cerulean Pharma Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Cerulean' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Cipher Pharmaceuticals, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Cipher' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Cipher' s drug delivery sales
- Competitor Ratio Analysis
- Debiopharm Group
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Debiopharm' s product pipeline
- Sales forecasts of products utilising the delivery technology
- DebioPharm' s drug delivery sales
- Competitor Ratio Analysis
- DelSite Biotechnologies, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- DelSite' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Depomed, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Depomed' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Depomed' s product sales
- Competitor Ratio Analysis
- Durect Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Durect' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Durect' s product sales
- Competitor Ratio Analysis
- Elan Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Elan' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Elan' s drug delivery sales
- Competitor Ratio Analysis
- Elite Pharmaceuticals, Inc
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Elite' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Elite' s product sales
- Competitor Ratio Analysis
- Endo Pharmaceuticals, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Endo' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Endo' s product sales
- Competitor Ratio Analysis
- Ethypharm SA
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Ethypharm' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Ethypharm' s product sales
- Competitor Ratio Analysis
- Eurand
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Eurand' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Eurand' s product sales
- Competitor Ratio Analysis
- Flamel Technologies, Inc.
- Proprietary delivery technology
- Flamel' s Medusa technology
- Flamel' s Micropump technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Flamel' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Flamel' s product sales
- Competitor Ratio Analysis
- Glycologic, Ltd.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Glycologic' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- KV Pharmaceuticals, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- KV' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Labopharm, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Labopharm' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Labopharm' s product sales
- Competitor Ratio Analysis
- Lavipharm SA
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Lavipharm' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Nano Interface Technology
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NITI' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- OctoPlus N.V.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- OctoPlus' product pipeline
- Sales forecasts of products utilising the delivery technology
- OctoPlus' product sales
- Competitor Ratio Analysis
- Penwest Pharmaceuticals
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Penwest' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Penwest' s product sales
- Competitor Ratio Analysis
- SCOLR Pharma, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- SCOLR' s product pipeline
- Sales forecasts of products utilising the delivery technology
- SCOLR' s drug delivery sales
- Competitor Ratio Analysis
- Shire, Plc
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Shire' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Shire' s leading drug delivery product sales
- Competitor Ratio Analysis
- Skinvisible, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Skinvisible' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- SkyePharma
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- SkyePharma' s product pipeline
- Sales forecasts of products utilising the delivery technology
- SkyePharma' s product sales
- Competitor Ratio Analysis
- Spherics
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Spheric' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Spheric' s product sales
- Competitor Ratio Analysis
- Watson Pharmaceuticals
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Watson' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Watson' s drug delivery sales
- Competitor Ratio Analysis
- APPENDIX 1
- Global controlled-release approved drugs sales 2008-2018 (US$million)
- APPENDIX 2
- Global controlled-release developmental drugs sales 2008-2018 (US$million)
- APPENDIX 3
- Competitor Ratio Analysis Criteria
- Key Controlled-release delivery companies by 2015
- BIBLIOGRAPHY
- GLOSSARY
- ACRONYMS
- ENDNOTES
DRUG DELIVERY TECHNOLOGIES: NANOTECHNOLOGY
- EXECUTIVE SUMMARY
- INTRODUCTION
- Overview of nanotechnology: past, present & future
- Multifunctional nanotechnology platform
- Nanotechnology: motivators & resistors
- Motivators
- Nanotechnology motivators
- Resistors
- Nanomedicines, formulations and product regeneration
- Failure rates at each stage of clinical drug development
- NANOTECHNOLOGY IN DRUG DELIVERY
- Core nanotechnology used by the pharma industry
- Nano-engineered drugs
- Nano-carriers
- Dendrimer structure
- Liposome structure
- Micelle structure
- Polymeric nanoparticle structure - Abraxane
- Current therapeutic applications of nanotechnology in drug delivery
- Leading brands that utilise nanotechnology delivery
- Nanotechnology-enabled approved drugs
- Future commercial applications & opportunities
- STRATEGIES OF DRUG DELIVERY COMPANIES
- Leading nanotechnology drug delivery companies
- Leading nanotechnology-enabled drug delivery companies
- Partnerships & acquisitions
- Strategic development & commercialisation partnerships and joint
ventures
- Mergers, acquisitions, start ups & spin offs
- Recent partnerships & acquisitions in the nanotechnology field
- Intellectual Property
- THE NANOTECHNOLOGY MARKET
- Now 2009
- Leading approved nano-enabled product sales
- Leading companies developing nano-enabled product sales
- Future 2018
- Novel nano-enabled product sales
- Global nano-enabled product sales
- COMPETITOR ANALYSIS
- Movers & Shakers: Cutting edge or losing their grip
- Movers & shakers in nanotechnology drug delivery systems
- COMPANY PROFILES
- Abraxis Bioscience
- Proprietary delivery technology
- Abraxis Protosphere - nab technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Abraxis' product pipeline
- Sales forecasts of products utilising the delivery technology
- Abraxis' sales forecasts
- Competitor Ratio Analysis
- Access Pharmaceuticals
- Proprietary delivery technology
- ProLindac nanoparticulate prodrug
- Cobalamin coated nanoparticulates
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Access Pharmaceuticals product pipeline
- Sales forecasts of products utilising the delivery technology
- Access' sales forecasts
- Competitor Ratio Analysis
- AlphaRx Corporation
- Proprietary delivery technology
- Nanoparticle targeted delivery & uptake
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- AlphaRx' product pipeline
- Sales forecasts of products utilising the delivery technology
- AlphaRx' pharmaceuticals sales
- Competitor Ratio Analysis
- ALZA Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Sales forecasts of products utilising the delivery technology
- ALZA' s drug delivery sales
- Competitor Ratio Analysis
- Aphios Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Aphios' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- APR Applied Pharma Research
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- APR' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- BioSante Pharmaceuticals
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- BioSante' s CaP product pipeline
- Sales forecasts of products utilising the delivery technology
- BioSante' s drug delivery sales
- Competitor Ratio Analysis
- Calando Pharmaceuticals
- Proprietary delivery technology
- Schematic of cyclodextrin polymeric nanoparticles
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Calando' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Calando' s sales forecasts
- Competitor Ratio Analysis
- Camurus AB
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Camurus AB' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Camurus AB' s drug delivery sales
- Competitor Ratio Analysis
- Cerulean Pharma Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Cerulean' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- CytImmune Sciences Inc.
- Proprietary delivery technology
- CytImmune' s Colloidal Gold Nanoparticle Delivery
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- CytImmune' s' product pipeline
- Sales forecasts of products utilising the delivery technology
- CytImmune' s sales forecasts
- Competitor Ratio Analysis
- Elan Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Elan' s NanoCrystal product portfolio
- Sales forecasts of products utilising the delivery technology
- Elan' s drug delivery sales
- Competitor Ratio Analysis
- Enzon Pharmaceuticals, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Enzon' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Enzon' s targeted product sales
- Competitor Ratio Analysis
- Gilead Sciences
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Gilead Sciences' product pipeline
- Sales forecasts of products utilising the delivery technology
- Gilead Sciences' drug delivery sales
- Competitor Ratio Analysis
- Introgen Therapeutics
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Introgen' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Introgen' s sales forecasts
- Competitor Ratio Analysis
- Mersana Therapeutics
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Mersana' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Mersana' s sales forecasts
- Competitor Ratio Analysis
- Nano Interface Technology
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NITI' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Nano S Biotechnology GmbH
- Proprietary delivery technology
- S-Layer Technology Platform
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Nano S' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- NanoBio Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NanoBio' s product pipeline
- Sales forecasts of products utilising the delivery technology
- NanoBio' s drug delivery sales
- Competitor Ratio Analysis
- NanoBioMagnetics
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NanoBioMagnetics' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Nanobiotix
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Nanobiotix' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- NanoCarrier
- Proprietary delivery technology
- Micellar Nanoparticles
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NanoCarrier' s product pipeline
- Sales forecasts of products utilising the delivery technology
- NanoCarrier' s drug delivery sales
- Competitor Ratio Analysis
- Nanotechnology Victoria, Ltd.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NanoVic' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- NanoMaterials Technology
- Proprietary delivery technology
- High Gravity Controlled Precipitation (HCGP) of nanomaterials
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NanoMaterial' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Nanotherapeutics
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Nanotherapeutics' product pipeline
- Sales forecasts of products utilising the delivery technology
- Nanotherapeutics' drug delivery sales
- Competitor Ratio Analysis
- Novavax
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Novavax' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Novavax' s drug delivery sales
- Competitor Ratio Analysis
- SkyePharma
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- SkyePharma' s product pipeline
- Sales forecasts of products utilising the delivery technology
- SkyePharma' s product sales
- Competitor Ratio Analysis
- Spherics
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Spheric' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Starpharma
- Proprietary delivery technology
- Dendrimer nanotechnology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Starpharma' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Starpharma' s product sales
- Competitor Ratio Analysis
- APPENDIX 1
- Global nanotechnology approved drugs sales 2008-2018
- APPENDIX 2
- Global nanotechnology developmental drugs sales 2008-2018
- APPENDIX 3
- Competitor Ratio Analysis Criteria
- Key nanotechnology delivery companies by 2018
- GLOSSARY
- ACRONYMS
- BIBLIOGRAPHY
- ENDNOTES
DRUG DELIVERY TECHNOLOGIES: NUCLEIC ACID
- EXECUTIVE SUMMARY
- INTRODUCTION
- Overview of delivery technologies for genetic material: past, present &
future
- Leading technology platforms for the delivery of genetic material
- Nucleic acid delivery: motivators & resistors
- Nucleic acid technology motivators
- Motivators
- Nucleic acid technology resistors
- Resistors
- ADVANCED NUCLEIC ACID DELIVERY TECHNOLOGIES
- Types of nucleic acid-based products under development by the pharma
industry
- Viral vector delivery of nucleic acids
- Schematic of gene therapy utilising HVJ envelope - virosome
- Bacterial vector delivery of nucleic acids
- Non-viral vector delivery of nucleic acids
- Chemical Technologies
- Stable nucleic acid-lipid particles
- Targeted nanoparticles
- Physical Technologies
- Schematic of Zosano Pharma' s Patch Technology
- Advantages and disadvantages of nucleic acid platforms
- Current therapeutic applications for the viral and non-viral delivery of
nucleic acids
- Leading nucleic acid based products in development
- Nucleic acid-based approved/filed drugs
- Selection of gene therapies in clinical development
- Selection of RNA therapeutics in clinical development
- Selection of DNA vaccines in clinical development
- Future commercial applications & opportunities
- STRATEGIES OF DRUG DELIVERY COMPANIES
- Leading nucleic acid drug delivery companies
- Leading nucleic acid drug delivery specialists
- Partnerships & acquisitions
- Strategic developmental & commercialisation partnerships
- Mergers, acquisitions & joint ventures
- Recent partnerships & acquisitions in the nucleic acid field
- Intellectual Property
- THE VIRAL AND NON-VIRAL VECTOR DELIVERY MARKET
- Now 2009
- Approved nucleic acid product sales
- Future 2018
- Novel nucleic acid product sales
- Global controlled release product sales
- COMPETITOR ANALYSIS
- Movers & Shakers: Cutting edge or losing their grip
- Movers & shakers in nucleic acid drug delivery systems
- COMPANY PROFILES
- Alnylam Pharmaceuticals
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Alnylam' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Alnylam' s sales forecasts
- Competitor Ratio Analysis
- AlphaVax, Inc.
- Proprietary delivery technology
- The alphavaccine platform system
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- AlphaVax' product pipeline
- Sales forecasts of products utilising the delivery technology
- AlphaVax' sales forecasts
- Competitor Ratio Analysis
- Altea Therapeutics, Inc.
- Proprietary delivery technology
- Altea Therapeutics' Passport Patch
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Altea Therapeutics' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- AP Pharma, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- AP Pharma' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- ArmaGen Technologies
- Proprietary delivery technology
- ArmaGen' s BBB delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- ArmaGen Technologies' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- BioDelivery Sciences International
- Proprietary delivery technology
- Bioral Technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- BDSI' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Calando Pharmaceuticals
- Proprietary delivery technology
- Schematic of cyclodextrin polymeric nanoparticles
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Calando' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Calando' s sales forecasts
- Competitor Ratio Analysis
- Cequent Pharmaceuticals
- Proprietary delivery technology
- Application in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Cequent' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Cequent' s sales forecasts
- Competitor Ratio Analysis
- Copernicus Therapeutics
- Proprietary delivery technology
- Uptake and trafficking of condensed nanoparticle DNA
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Copernicus' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Diatos SA
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Diatos' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- DOR BioPharma, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- DOR' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Expression Genetics, Inc.
- Proprietary delivery technology
- TheraPlas Technology Platform
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- EGEN' s product pipeline
- Sales forecasts of products utilising the delivery technology
- EGEN' s sales forecasts
- Competitor Ratio Analysis
- Inovio Biomedical Corporation
- Proprietary delivery technology
- Inovio' s gene delivery platform
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Inovio' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Inovio' s sales forecasts
- Competitor Ratio Analysis
- MaxCyte, Inc.
- Proprietary delivery technology
- MaxCyte' s GT exvivo cell loading system
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- MaxCyte' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Nanotherapeutics
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Nanotherapeutics' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- NeoPharm
- Proprietary delivery technology
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NeoPharm' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Novagali Pharma SA
- Proprietary delivery technology
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Novagali' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Oxford Biomedica
- Proprietary delivery technology
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Oxford Biomedica' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Oxford Biomedica' s sales forecasts
- Competitor Ratio Analysis
- PCI Biotech
- Proprietary delivery technology
- PCI enhances siRNA' s gene silencing effect and improves gene delivery
- Applications in the pharma industry
- Potential applications for improving the delivery of a range of drug
types
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- PCI' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Silence Therapeutics plc
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Silence Therapeutics' product pipeline
- Sales forecasts of products utilising the delivery technology
- Silence Therapeutics' sales forecasts
- Competitor Ratio Analysis
- Targeted Genetics Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- TGEN' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Targeted Genetics sales forecasts
- Competitor Ratio Analysis
- Tekmira Pharmaceuticals Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Tekmira' s product pipeline
- ales forecasts of products utilising the delivery technology
- Tekmira' s sales forecasts
- Competitor Ratio Analysis
- TissueGene, Inc.
- Proprietary delivery technology
- Manufacturing TissueGene-C cell mediated gene therapies
- Applications in the pharma industry
- Application of TissueGene-C cell mediated gene therapy in orthopaedics
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- TissueGene' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Vical, Inc.
- Proprietary delivery technology
- Schematic of p-DNA delivery and utilisation in DNA vaccines
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Vical' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Vical' s sales forecasts
- Competitor Ratio Analysis
- Zosano Pharma, Inc.
- Proprietary delivery technology
- ZP Patch Technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Zosano Pharma' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- APPENDIX 1
- Global nucleic acid approved drugs sales 2008-2018
- APPENDIX 2
- Global nucleic acid developmental drugs sales 2008-2018
- APPENDIX 3
- Competitor Ratio Analysis Criteria
- Key Nucleic acid delivery companies by 2018
- GLOSSARY
- ACRONYMS
- ENDNOTES
DRUG DELIVERY TECHNOLOGIES: TARGETED
- EXECUTIVE SUMMARY
- INTRODUCTION
- Overview of delivery technologies for targeted delivery: past, present &
future
- Leading technology platforms for systemic targeted drug delivery
- Systemic targeted delivery: motivators & resistors
- Motivators
- Systemic targeted delivery technology motivators
- Resistors
- Systemic targeted delivery technology resistors
- TARGETED DELIVERY TECHNOLOGIES
- Types of systemic targeted delivery platform in development in the
pharma industry
- Targeting ligands
- Antibody fragment conjugate delivery
- Antibody-directed enzyme pro-drug targeted delivery
- Peptide-induced release for targeted delivery
- Small molecule conjugate delivery
- Nucleomic mediated targeted intranuclear delivery
- Cobalamin mediated targeted intracellular delivery
- Non-biological targeting platforms
- Magnetically targeted delivery
- Photosensitive targeted delivery
- Current therapeutic applications for systemic targeted delivery
- Leading systemic targeted products in development
- Approved systemic and targeted drugs
- Future commercial applications & opportunities
- STRATEGIE S OF DRUG DELIVERY COMPANIES
- Leading targeted drug delivery companies
- Leading systemic targeted delivery specialists
- Partnerships & acquisitions
- Strategic alliances
- Strategic acquisitions
- Recent market activity in targeted delivery companies
- Intellectual Property
- Targeted drug delivery patents
- THE TARGETED DELIVERY MARKET
- Now 2009
- Approved targeted delivery product sales
- Future 2018
- Global targeted-release product sales
- Novel targeted delivery product sales
- COMPETITOR ANALYSIS
- Movers & Shakers: Cutting edge or losing their grip
- Movers & shakers in targeted drug delivery systems
- Abraxis Biosciences
- Proprietary delivery technology
- Abraxis Protosphere - nab technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Abraxis' product pipeline
- Sales forecasts of products utilising the delivery technology
- Abraxis' targeted sales forecasts
- Competitor Ratio Analysis
- Access Pharmaceuticals
- Proprietary delivery technology
- Cobalamin targeted delivery
- Schematic of targeted nanoparticle
- Targeted delivery of cancer subtypes via folate polymer, Vitamin B12
polymer and biotin polymers
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Access Pharmaceuticals' product pipeline
- Sales forecasts of products utilising the delivery technology
- Access Pharmaceuticals' sales forecasts
- Competitor Ratio Analysis
- ALZA Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- ALZA' s targeted product pipeline
- Sales forecasts of products utilising the delivery technology
- ALZA' s drug delivery sales
- Competitor Ratio Analysis
- ArmaGen Technologies
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- ArmaGen Technologies' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Avidimer Therapeutics
- Proprietary delivery technology
- Targeted avidimer for methotrexate delivery
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Avidimer' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Calando Pharmaceuticals
- Proprietary delivery technology
- Schematic of Cyclosert technology
- Schematic of RONDEL technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Calando' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Calando' s sales forecasts
- Competitor Ratio Analysis
- Cell Therapeutics
- Proprietary delivery technology
- CTI' s polyglutamate polymer technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- CTI' s product pipeline
- Sales forecasts of products utilising the delivery technology
- CTI' s targeted drug delivery sales
- Competitor Ratio Analysis
- Cerulean Pharma Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Cerulean' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Copernicus Therapeutics
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Copernicus' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- CytImmune Sciences Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- CytImmune' s' product pipeline
- Sales forecasts of products utilising the delivery technology
- CytImmune' s sales forecasts
- Competitor Ratio Analysis
- Diatos SA
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Diatos' product pipeline
- Sales forecasts of products utilising the delivery technology
- Diatos' targeted drug delivery sales
- Competitor Ratio Analysis
- Enzon Pharmaceuticals, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Enzon' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Enzon' s targeted product sales
- Competitor Ratio Analysis
- Endocyte Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Endocyte' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Endocyte' s targeted drug delivery sales
- Competitor Ratio Analysis
- Eurand
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Eurand' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- ImmunoGen
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- ImmunoGen' s product pipeline
- Sales forecasts of products utilising the delivery technology
- ImmunoGen' s targeted delivery sales
- Competitor Ratio Analysis
- ImaRx Therapeutics
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- ImaRx' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- NanoBioMagnetics, Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NanoBioMagnetics' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Nanobiotix
- Proprietary delivery technology
- Nanobiotix' NanoXray
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Nanobiotix' product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- NanoCarrier
- Proprietary delivery technology
- NanoCoat technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NanoCarrier' s product pipeline
- Sales forecasts of products utilising the delivery technology
- NanoCarrier' s targeted drug delivery sales
- Competitor Ratio Analysis
- Nano Interface Technology
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NITI' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Nektar Therapeutics
- Proprietary delivery technology
- Large molecule conjugate delivery
- Small molecule conjugate delivery
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Nektar' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Nektar' s targeted sales forecasts
- Competitor Ratio Analysis
- NeoPharm
- Proprietary delivery technology
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- NeoPharm' s product pipeline
- Sales forecasts of products utilising the delivery technology
- NeoPharm' s targeted product pipeline
- Competitor Ratio Analysis
- Novosom AG
- Proprietary delivery technology
- Schematic of SMARTICLES mechanism of targeted delivery
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Novosom' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- PCI Biotech Holding ASA
- Proprietary delivery technology
- Potential applications for improving the delivery of a range of drug
types
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- PCI' s product pipeline
- Sales forecasts of products utilising the delivery technology
- PCI' s targeted product sales
- Competitor Ratio Analysis
- Quest PharmaTech
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Quest PharmaTech' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Quest PharmaTech' s targeted product sales
- Competitor Ratio Analysis
- Seattle Genetics
- Proprietary delivery technology
- Schematic of ADC' s
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Seattle Genetic' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Seattle Genetic' s targeted delivery sales
- Competitor Ratio Analysis
- Spherics, Inc.
- Proprietary delivery technology
- Spherics' Oral Targeted Delivery Technologies
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Spheric' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Spheric' s product sales
- Competitor Ratio Analysis
- Starpharma
- Proprietary delivery technology
- Starpharma' s polyvalent dendrimers
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Starpharma' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Competitor Ratio Analysis
- Supratek Pharma Inc.
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Supratek' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Supratek' s product sales
- Competitor Ratio Analysis
- Tekmira Pharmaceuticals Corporation
- Proprietary delivery technology
- Applications in the pharma industry
- Management/technical expertise
- Competition within the delivery technology sector
- Products in development/approved utilising the delivery technology
- Tekmira' s product pipeline
- Sales forecasts of products utilising the delivery technology
- Tekmira' s sales forecasts
- Competitor Ratio Analysis
- APPENDIX 1
- Global targeted approved drugs sales 2008-2018 (US$ millions)
- APPENDIX 2
- Global targeted developmental drugs sales 2008-2018 (US$ millions)
- APPENDIX 3
- Competitor Ratio Analysis Criteria
- Key targeted delivery companies by 2018
- GLOSSARY
- ACRONYMS
- BIBLIOGRAPHY
- ENDNOTES
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