U.S. Market for Interventional Cardiology Devices 2009

Table of Contents

TABLE OF CONTENTS

LIST OF FIGURES

LIST OF CHARTS

EXECUTIVE SUMMARY

• 1.1 MARKET FOR INTERVENTIONAL CARDIOLOGY DEVICES
• 1.2 BARE-METAL AND DRUG-ELUTING STENTS
• 1.3 PTCA AND CUTTING BALLOONS
• 1.4 BALLOON-INFLATION SYRINGES AND ANGIOPLASTY KITS
• 1.5 INTERVENTIONAL CATHETERS
• 1.6 INTERVENTIONAL GUIDEWIRES
• 1.7 EMBOLIC PROTECTION DEVICES
• 1.8 ATHERECTOMY DEVICES
• 1.9 THROMBECTOMY DEVICES
• 1.10 CHRONIC TOTAL OCCLUSION CROSSERS
• 1.11 INTRODUCER SHEATHS
• 1.12 VASCULAR CLOSURE DEVICES
• 1.13 DIAGNOSTIC CORONARY CATHETERS AND GUIDEWIRES
• 1.14 FRACTIONAL FLOW RESERVE GUIDEWIRES
• 1.15 IVUS CATHETERS
• 1.16 OPTICAL COHERENCE TOMOGRAPHY (OCT) DEVICES
• 1.17 VULNERABLE PLAQUE DEVICES
• 1.18 PFO, ASD AND VSD DEVICES
• 1.19 PERCUTANEOUS MITRAL VALVE REPAIR DEVICES
• 1.20 AORTIC HEART VALVE REPLACEMENT DEVICES
• 1.21 LEADING COMPETITORS

RESEARCH METHODOLOGY

• 2.1 RESEARCH SCOPE
• 2.2 IDATA' S 9-STEP METHODOLOGY
  • 2.2.1 Step 1: Project Initiation & Team Selection
  • 2.2.2 Step 2: Prepare Data Systems and Perform Secondary Research
  • 2.2.3 Step 3: Preparation for Interviews & Questionnaire Design
  • 2.2.4 Step 4: Performing Primary Research
  • 2.2.5 Step 5: Research Analysis: Establishing Baseline Estimates
  • 2.2.6 Step 6: Market Forecast and Analysis
  • 2.2.7 Step 7: Identify Strategic Opportunities
  • 2.2.8 Step 8: Final Review and Market Release
  • 2.2.9 Step 9: Customer Feedback and Market Monitoring

U.S. MARKET FOR INTERVENTIONAL CARDIOLOGY DEVICES

• 3.1 INTRODUCTION
• 3.2 OVERVIEW OF THE MARKET
• 3.3 MARKET SEGMENTED BY DEVICE TYPE
  • 3.3.1 Effects of the Economic Crisis
• 3.4 TREND ANALYSIS BY MARKET SEGMENT
• 3.5 MARKET DRIVERS
• 3.6 MARKET LIMITERS
• 3.7 COMPETITIVE ANALYSIS
• 3.8 MERGERS AND ACQUISITIONS

BARE-METAL AND DRUG-ELUTING STENTS

• 4.1 INTRODUCTION
• 4.2 POPULATION AT RISK
• 4.3 PROCEDURE NUMBERS
• 4.4 MARKET ANALYSIS & FORECAST
  • 4.4.1 Units Sold by Type
  • 4.4.2 Bare-Metal Stent Market
    • 4.4.2.1 Bare-Metal Stent Market Drivers
    • 4.4.2.2 Bare-Metal Stent Market Limiters
  • 4.4.3 Drug-Eluting Stent Market
    • 4.4.3.1 Drug-Eluting Stent Market Drivers
    • 4.4.3.2 Drug-Eluting Stent Market Limiters
  • 4.4.4 Stents in Development
    • 4.4.4.1 Bioabsorbable Stents
    • 4.4.4.2 Bifurcated Stents
• 4.5 STENT MARKET BY DELIVERY PLATFORM
• 4.6 STENT MARKET BY SIZE
• 4.7 COMPETITIVE ANALYSIS
  • 4.7.1 Bare-Metal Stents
  • 4.7.2 Drug-Eluting Stents
  • 4.7.3 Potential New Market Participants

PTCA AND CUTTING BALLOON CATHETERS

• 5.1 INTRODUCTION
  • 5.1.1 The Problem of Restenosis
  • 5.1.2 Conventional and Cutting Balloons
• 5.2 MARKET OVERVIEW
• 5.3 MARKET FOR PTCA BALLOONS
  • 5.3.1 Units Sold
  • 5.3.2 Market Analysis & Forecast
• 5.4 MARKET FOR CUTTING BALLOONS
  • 5.4.1 Device Penetration
  • 5.4.2 Market Analysis & Forecast
• 5.5 MARKET DRIVERS AND LIMITERS
  • 5.5.1 Market Drivers
  • 5.5.2 Market Limiters
• 5.6 NEW TECHNOLOGIES - DRUG-COATED BALLOON CATHETERS
• 5.7 COMPETITIVE ANALYSIS
  • 5.7.1 PTCA Balloon Catheters
  • 5.7.2 Cutting Balloon Catheters

BALLOON-INFLATION SYRINGES

• 6.1 INTRODUCTION
• 6.2 MARKET ANALYSIS & FORECAST
• 6.3 MARKET DRIVERS AND LIMITERS
  • 6.3.1 Market Drivers
  • 6.3.2 Market Limiters
• 6.4 COMPETITIVE ANALYSIS

ANGIOPLASTY KITS

• 7.1 INTRODUCTION
• 7.2 MARKET ANALYSIS & FORECAST
• 7.3 MARKET DRIVERS AND LIMITERS
  • 7.3.1 Market Drivers
  • 7.3.2 Market Limiters
• 7.4 COMPETITIVE ANALYSIS

INTERVENTIONAL CATHETERS

• 8.1 INTRODUCTION
• 8.2 UNITS SOLD
• 8.3 MARKET ANALYSIS & FORECAST
  • 8.3.1 Interventional Guiding Catheters Market
  • 8.3.2 Interventional Support Catheters Market
• 8.4 MARKET DRIVERS AND LIMITERS
  • 8.4.1 Market Drivers
  • 8.4.2 Market Limiters
• 8.5 COMPETITIVE ANALYSIS

INTERVENTIONAL GUIDEWIRES

• 9.1 INTRODUCTION
  • 9.1.1 Conventional and Specialty Guidewires
  • 9.1.2 Material and Fabrication
• 9.2 UNITS SOLD
• 9.3 MARKET ANALYSIS & FORECAST
  • 9.3.1 Conventional Guidewires Market
  • 9.3.2 Specialized Guidewires Market
• 9.4 MARKET DRIVER AND LIMITERS
  • 9.4.1 Market Drivers
  • 9.4.2 Market Limiters
• 9.5 COMPETITIVE ANALYSIS

EMBOLIC PROTECTION DEVICES

• 10.1 INTRODUCTION
  • 10.1.1 Saphenous Vein Grafts
  • 10.1.2 Protection Mechanism
• 10.2 MARKET ANALYSIS & FORECAST
• 10.3 PENETRATION RATE
• 10.4 MARKET DRIVERS AND LIMITERS
  • 10.4.1 Market Drivers
  • 10.4.2 Market Limiters
• 10.5 COMPETITIVE ANALYSIS

CORONARY ATHERECTOMY DEVICES

• 11.1 INTRODUCTION
  • 11.1.1 Atherectomy
  • 11.1.2 Technologies
    • 11.1.2.1 Mechanical
    • 11.1.2.2 Laser
    • 11.1.2.3 Directional Coronary Atherectomy (DCA)
• 11.2 MARKET ANALYSIS & FORECAST
• 11.3 PENETRATION RATE
• 11.4 MARKET DRIVERS AND LIMITERS
  • 11.4.1 Market Drivers
  • 11.4.2 Market Limiters
• 11.5 COMPETITIVE ANALYSIS

THROMBECTOMY DEVICES

• 12.1 INTRODUCTION
  • 12.1.1 Thrombosis and Drug-Eluting Stents
• 12.2 MARKET ANALYSIS & FORECAST
• 12.3 PENETRATION RATE
• 12.4 MARKET DRIVERS AND LIMITERS
  • 12.4.1 Market Drivers
  • 12.4.2 Market Limiters
• 12.5 COMPETITIVE ANALYSIS

CHRONIC TOTAL OCCLUSION CROSSERS

• 13.1 INTRODUCTION
• 13.2 POTENTIAL MARKET
• 13.3 MARKET ANALYSIS & FORECAST
• 13.4 PENETRATION RATE
• 13.5 MARKET DRIVERS AND LIMITERS
  • 13.5.1 Market Drivers
  • 13.5.2 Market Limiters
• 13.6 COMPETITIVE ANALYSIS

INTRODUCER SHEATHS

• 14.1 INTRODUCTION
• 14.2 MARKET ANALYSIS & FORECAST
  • 14.2.1 Units Sold
  • 14.2.2 Market Analysis & Forecast
• 14.3 MARKET DRIVERS AND LIMITERS
  • 14.3.1 Market Drivers
  • 14.3.2 Market Limiters
• 14.4 COMPETITIVE ANALYSIS

VASCULAR CLOSURE DEVICES

• 15.1 INTRODUCTION
  • 15.1.1 Manual Compression
  • 15.1.2 Invasive and Non-Invasive Devices
• 15.2 MARKET ANALYSIS & FORECAST
• 15.3 PENETRATION RATE
  • 15.3.1 Diagnostic Procedures
  • 15.3.2 Interventional Procedures
• 15.4 MARKET DRIVERS AND LIMITERS
  • 15.4.1 Market Drivers
  • 15.4.2 Market Limiters
• 15.5 COMPETITIVE ANALYSIS

DIAGNOSTIC CATHETERS AND GUIDEWIRES

• 16.1 INTRODUCTION
  • 16.1.1 Coronary Angiography
• 16.2 MARKET ANALYSIS & FORECAST
• 16.3 DIAGNOSTIC CATHETERS
  • 16.3.1 Market Analysis & Forecast
  • 16.3.2 Units Sold
  • 16.3.3 Units Sold Segmented by Size
  • 16.3.4 Competitive Analysis
• 16.4 DIAGNOSTIC GUIDEWIRES
  • 16.4.1 Market Analysis & Forecast
  • 16.4.2 Units Sold
  • 16.4.3 Competitive Analysis
• 16.5 FRACTIONAL FLOW RESERVE (FFR) GUIDEWIRES
  • 16.5.1 Market Analysis and Forecast
  • 16.5.2 Units Sold
  • 16.5.3 Competitive Analysis
• 16.6 MARKET DRIVERS AND LIMITERS
  • 16.6.1 Market Drivers
  • 16.6.2 Market Limiters

IVUS CATHETERS

• 17.1 INTRODUCTION
  • 17.1.1 Pre-Stenting Applications
  • 17.1.2 Post-Stenting Applications
  • 17.1.3 IVUS Console Penetration
• 17.2 MARKET ANALYSIS & FORECAST
• 17.3 PENETRATION RATE
• 17.4 MARKET DRIVERS AND LIMITERS
  • 17.4.1 Market Drivers
  • 17.4.2 Market Limiters
• 17.5 COMPETITIVE ANALYSIS

OPTICAL COHERENCE TOMOGRAPHY (OCT) DEVICES

• 18.1 INTRODUCTION
• 18.2 POTENTIAL MARKET
• 18.3 MARKET ANALYSIS AND FORECAST
• 18.4 MARKET DRIVERS AND LIMITERS
  • 18.4.1 Market Drivers
  • 18.4.2 Market Limiters
• 18.5 COMPETITIVE ANALYSIS

VULNERABLE PLAQUE DEVICES

• 19.1 INTRODUCTION
  • 19.1.1 Vulnerable Plaque Screening Technologies
    • 19.1.1.1 Intravascular Ultrasound (IVUS)
    • 19.1.1.2 Optical Coherence Tomography (OCT)
    • 19.1.1.3 Raman Spectroscopy
    • 19.1.1.4 Near Infrared (NIR) Spectroscopy
    • 19.1.1.5 Thermography
    • 19.1.1.6 Intravascular Magnetic Resonance Imaging (IVMRI)
    • 19.1.1.7 Computed Tomography (CT)
  • 19.1.2 Potential Vulnerable Plaque Treatments
    • 19.1.2.1 Stents
    • 19.1.2.2 Pharmaceuticals
    • 19.1.2.3 Photodynamic Therapies
    • 19.1.2.4 Cryotherapy
• 19.2 TARGET POPULATION
• 19.3 MARKET ANALYSIS AND FORECAST
  • 19.3.1 Total Market Potential
  • 19.3.2 Market Forecast
  • 19.3.3 Screening Market
  • 19.3.4 Treatment Market
• 19.4 COMPETITIVE ANALYSIS

PFO DEVICES

• 20.1 INTRODUCTION
• 20.2 MARKET ANALYSIS AND FORECAST
• 20.3 MARKET DRIVERS AND LIMITERS
  • 20.3.1 Market Drivers
  • 20.3.2 Market Limiters
• 20.4 COMPETITIVE ANALYSIS

ASD AND VSD DEVICES

• 21.1 INTRODUCTION
  • 21.1.1.1 Atrial Septal Defect (ASD)
  • 21.1.1.2 Ventricular Septal Defect (VSD)
• 21.2 MARKET ANALYSIS AND FORECAST
• 21.3 MARKET DRIVERS AND LIMITERS
  • 21.3.1 Market Drivers
  • 21.3.2 Market Limiters
• 21.4 COMPETITIVE ANALYSIS

PERCUTANEOUS MITRAL VALVE REPAIR DEVICES

• 22.1 INTRODUCTION
  • 22.1.1 Percutaneous Mitral Valve Repair (PMVR)
• 22.2 TARGET POPULATION
• 22.3 POTENTIAL MARKET
• 22.4 MARKET DRIVERS AND LIMITERS
  • 22.4.1 Market Drivers
  • 22.4.2 Limiters
• 22.5 COMPETITIVE ANALYSIS

PERCUTANEOUS AORTIC HEART VALVE REPLACEMENT DEVICES

• 23.1 INTRODUCTION
• 23.2 MARKET ANALYSIS AND FORECAST
  • 23.2.1 Revenue Probability
• 23.3 MARKET DRIVERS AND LIMITERS
  • 23.3.1 Market Drivers
  • 23.3.2 Market Limiters
• 23.4 COMPETITIVE ANALYSIS

ABBREVIATIONS

LIST OF FIGURES

EXECUTIVE SUMMARY 1

RESEARCH METHODOLOGY 12

U.S. MARKET FOR INTERVENTIONAL CARDIOLOGY DEVICES 23

• Figure 3-1: Market for Interventional Cardiology Segmented by Device Type, U.S., 2005 - 2015 26
• Figure 3-2: Trend Analysis by Market Segment, Growth Rates of the Market for Interventional Cardiology, U.S., 2005 - 2015 31
• Figure 3-3: Market Drivers, Market for Interventional Cardiology, U.S, 2008 34
• Figure 3-4: Market Limiters, Market for Interventional Cardiology, U.S., 2008 35
• Figure 3-5: Leading Competitors by Market Segment, U.S. Market for Interventional Cardiology, 2008 37

BARE-METAL AND DRUG-ELUTING STENTS 43

• Figure 4-1: Population at Risk, Market for Interventional Cardiology, U.S., 2005 - 2015 46
• Figure 4-2: Angiography and Angioplasty Procedures, U.S., 2005 - 2015 49
• Figure 4-3: Market for Coronary Stents by Type, U.S., 2005 - 2015 52
• Figure 4-4: Units Sold, Market for Coronary Stents, U.S., 2005 - 2015 54
• Figure 4-5: Coronary Stent Units by Type, U.S., 2005 - 2015 55
• Figure 4-6: Market for Bare-Metal Stents, U.S., 2005 - 2015 56
• Figure 4-7: Market Drivers and Limiters, Market for Bare-Metal Stents, U.S., 2008 59
• Figure 4-8: Market for Drug-Eluting Stents, U.S., 2005 - 2015 61
• Figure 4-9: Market Drivers and Limiters, Market for Drug-Eluting Stents, U.S., 2008 65
• Figure 4-10: Coronary Stent Platforms in Development Not Approved by the FDA, 2008 66
• Figure 4-11: Potential Market for Bioabsorbable Stents, U.S., 2013 - 2015 68
• Figure 4-12: Potential Market for Bifurcated Stents, U.S., 2010 - 2015 70
• Figure 4-13: Market for Coronary Stents by Delivery Platform, Units Sold, U.S., 2005 - 2015 71
• Figure 4-14: Market for Coronary Stents by Size, U.S., 2008 73
• Figure 4-15: Leading Competitors, Market for Bare-Metal Stents, U.S., 2008 76
• Figure 4-16: Leading Competitors, U.S. Market for Drug-Eluting Stents, 2008 79

PTCA AND CUTTING BALLOON CATHETERS 84

• Figure 5-1: Market for PTCA and Cutting Balloon Catheters, U.S., 2005 - 2015 85
• Figure 5-2: Units Sold, Market for PTCA Balloon Catheters, U.S., 2005 - 2015 87
• Figure 5-3: Market for PTCA Balloon Catheters, U.S., 2005 - 2015 88
• Figure 5-4: Units Sold, Market for Cutting Balloon Catheters, U.S., 2005 - 2015 90
• Figure 5-5: Market for Cutting Balloon Catheters, U.S., 2005 - 2015 91
• Figure 5-6: Market Drivers and Limiters, U.S. Market for PTCA and Cutting Balloon Catheters, 2008 94
• Figure 5-7: Leading Competitors, Market for PTCA Balloon Catheters, U.S., 2008 95
• Figure 5-8: Leading Competitors, Market for PTCA Balloon Catheters, U.S., 2008 97

BALLOON-INFLATION SYRINGES 98

• Figure 6-1: Market for Balloon-Inflation Syringes, U.S., 2005 - 2015 99
• Figure 6-2: Market Drivers and Limiters, U.S. Market for Balloon-Inflation Syringes, 2008 101
• Figure 6-3: Leading Competitors, Market for Balloon-Inflation Syringes, U.S., 2008 102

ANGIOPLASTY KITS 104

• Figure 7-1: Market for Angioplasty Accessory Kits, U.S., 2005 - 2015 105
• Figure 7-2: Market Drivers and Limiters, Market for Angioplasty Accessory Kits, U.S., 2005 - 2015 107
• Figure 7-3: Leading Competitors, Market for Angioplasty Accessory Kits, U.S., 2005 - 2015 108

INTERVENTIONAL CATHETERS 110

• Figure 8-1: Units Sold, Market for Interventional Coronary Catheters, U.S., 2005 - 2015 111
• Figure 8-2: Market for Interventional Coronary Catheters by Device Type, U.S., 2005 - 2015 112
• Figure 8-3: Market for Interventional Guiding Catheters, U.S., 2005 - 2015 114
• Figure 8-4: Market for Interventional Support Catheters, U.S., 2005 - 2015 115
• Figure 8-5: Market Drivers and Limiters, Market for Interventional Coronary Catheters, U.S., 2008 117
• Figure 8-6: Leading Competitors, Market for Interventional Coronary Catheters, U.S., 2008 118

INTERVENTIONAL GUIDEWIRES 120

• Figure 9-1: Units Sold, Market for Interventional Coronary Guidewires, U.S., 2005 - 2015 121
• Figure 9-2: Market for Interventional Coronary Guidewires by Device Type, U.S., 2005 - 2015 123
• Figure 9-3: Market for Interventional Coronary Conventional Guidewires, U.S., 2005 - 2015 125
• Figure 9-4: Market for Interventional Coronary Specialized Guidewires, U.S., 2005 - 2015 126
• Figure 9-5: Market Drivers and Limiters, Market for Interventional Coronary Guidewires, U.S., 2008 127
• Figure 9-6: Leading Competitors, Market for Interventional Coronary Guidewires, U.S., 2008 128

EMBOLIC PROTECTION DEVICES 130

• Figure 10-1: Market for Coronary Embolic Protection Devices, U.S., 2005 - 2015132
• Figure 10-2: Penetration Rate, Market for Coronary Embolic Protection Devices, U.S., 2005 - 2015 135
• Figure 10-3: Market Drivers and Limiters, Market for Coronary Embolic Protection Devices, U.S., 2008 137
• Figure 10-4: Leading Competitors, Market for Coronary Embolic Protection Devices, U.S., 2008 138

CORONARY ATHERECTOMY DEVICES 140

• Figure 11-1: Market for Coronary Atherectomy Devices, U.S., 2005 - 2015 142
• Figure 11-2: Penetration Rate, Market for Coronary Atherectomy Devices, U.S., 2005 - 2015 144
• Figure 11-3: Market Drivers and Limiters, U.S. Market for Coronary Atherectomy Devices, 2008 146
• Figure 11-4: Leading Competitors, Market for Coronary Atherectomy Devices, U.S., 2008 147

THROMBECTOMY DEVICES 149

• Figure 12-1: Market for Coronary Thrombectomy Devices, U.S., 2005 - 2015 150
• Figure 12-2: Penetration Rate, Market for Coronary Thrombectomy Devices, U.S., 2005 - 2015 152
• Figure 12-3: Market Drivers and Limiters, Market for Coronary Thrombectomy Devices, U.S., 2008 153
• Figure 12-4: Leading Competitors, Market for Coronary Thrombectomy Devices, U.S., 2008 154

CHRONIC TOTAL OCCLUSION CROSSERS 156

• Figure 13-1: Potential Market for Chronic Total Occlusion Crossers, Market for Interventional Cardiology, U.S., 2005 - 2015 157
• Figure 13-2: Market for Coronary Chronic Total Occlusion Crossers, U.S., 2005 - 2015 158
• Figure 13-3: Penetration Rate, Market for Coronary Chronic Total Occlusion Crossers, U.S., 2005 - 2015 160
• Figure 13-4 Market Drivers and Limiters, Market for Coronary Chronic Total Occlusion Crossers, U.S., 2008 163
• Figure 13-5: Leading Competitors, Market for Coronary Chronic Total Occlusion Crossers, U.S., 2008 164

INTRODUCER SHEATHS 166

• Figure 14-1: Units Sold, Coronary Market for Introducer Sheaths, U.S., 2005 - 2015 167
• Figure 14-2: Coronary Market for Introducer Sheaths, U.S., 2005 - 2015 168
• Figure 14-3: Market Drivers and Limiters, U.S. Market for Introducer Sheaths, 2008 170
• Figure 14-4: Leading Competitors, Market for Introducer Sheaths, U.S., 2008 171

VASCULAR CLOSURE DEVICES 173

• Figure 15-1: Market for Coronary Vascular Closure Devices (Invasive and Non-Invasive), U.S., 2005 - 2015 174
• Figure 15-2: Penetration Rate, Market for Coronary Vascular Closure Devices (Invasive and Non-Invasive), U.S., 2005 - 2015 177
• Figure 15-3: Market Drivers and Limiters, Market for Coronary Vascular Closure Devices, U.S., 2008 179
• Figure 15-4: Leading Competitors, Market for Coronary Vascular Closure Devices, U.S., 2008 181

DIAGNOSTIC CATHETERS AND GUIDEWIRES 183

• Figure 16-1: Market for Diagnostic Coronary Catheters and Guidewires, U.S., 2005 - 2015 184
• Figure 16-2: Market for Diagnostic Coronary Catheters, U.S., 2005 - 2015 186
• Figure 16-3: Units Sold, Market for Diagnostic Coronary Catheters, U.S., 2005 - 2015 188
• Figure 16-4: Units Sold Segmented by Size, Market for Diagnostic Coronary Catheters, U.S., 2005 - 2015 189
• Figure 16-5: Leading Competitors, Market for Diagnostic Coronary Catheters, U.S., 2008 191
• Figure 16-6: Market for Diagnostic Coronary Guidewires, U.S., 2005 - 2015 193
• Figure 16-7: Units Sold, Market for Diagnostic Coronary Guidewires, U.S., 2005 - 2015 195
• Figure 16-8: Leading Competitors, Market for Diagnostic Coronary Guidewires, U.S., 2008 196
• Figure 16-9: Market for FFR Guidewires, U.S., 2005 - 2015 198
• Figure 16-10: Units Sold, Market for FFR Guidewires, U.S., 2005 - 2015 200
• Figure 16-11: Leading Competitors in the FFR Guidewire Market, U.S., 2008 201
• Figure 16-12: Market Drivers and Limiters, Market for Diagnostic Coronary Catheters and Guidewires, U.S., 2008 203

IVUS CATHETERS 204

• Figure 17-1: IVUS Console Penetration Rate, U.S., 2005 - 2015 205
• Figure 17-2: Market for IVUS Catheters, U.S., 2005 - 2015 206
• Figure 17-3: Penetration Rate, Market for IVUS Catheters, U.S., 2005 - 2015 208
• Figure 17-4: Market Drivers and Limiters, Market for IVUS Catheters, U.S., 2008210
• Figure 17-5: Leading Competitors, Market for IVUS Catheters, U.S., 2005 - 2015211

OPTICAL COHERENCE TOMOGRAPHY (OCT) DEVICES 212

• Figure 18-1: Potential Market for OCT Catheters, U.S., 2010 - 2015 215
• Figure 18-2: Potential Market for OCT Consoles, U.S., 2010 - 2015 217
• Figure 18-3: Potential Market for Coronary OCT Devices, U.S., 2010 - 2015 217
• Figure 18-4: Market Drivers and Limiters in the OCT Market, U.S., 2008 219

VULNERABLE PLAQUE DEVICES 222

• Figure 19-1: Target Population, Potential Market for Vulnerable Plaque Screening, U.S., 2005 - 2015 227
• Figure 19-2: Maximum Potential Market for Vulnerable Plaque, U.S., 2010 - 2015 228
• Figure 19-3: Forecasted Potential Market for Vulnerable Plaque, U.S., 2010 - 2015 230
• Figure 19-4: Forecasted Potential Market for Vulnerable Plaque Screening, U.S., 2010 - 2015 233
• Figure 19-5 : Forecasted Potential Market for Vulnerable Plaque Treatment, U.S., 2010 - 2015 235
• Figure 19-6: Potential Competitors in the U.S. Market for Vulnerable Plaque Devices 239

PFO DEVICES 240

• Figure 20-1: Market for PFO Devices, U.S., 2005 - 2015 241
• Figure 20-2: Market Drivers and Limiters in the PFO Devices Market, U.S., 2008244
• Figure 20-3: Leading Competitors, Market for PFO Devices, U.S., 2008 246

ASD AND VSD DEVICES 248

• Figure 21-1: Market for ASD and VSD Devices, U.S., 2005 - 2015 249
• Figure 21-2: Market Drivers and Limiters in the ASD and VSD Devices Market, U.S., 2008 251
• Figure 21-3: Leading Competitors, Market for ASD and VSD Devices, U.S., 2008253

PERCUTANEOUS MITRAL VALVE REPAIR DEVICES 255

• Figure 22-1: Target Population, Potential Market for PMVR Devices, U.S., 2010 - 2015 256
• Figure 22-2: Potential Market for Percutaneous Mitral Valve Repair Devices, U.S., 2010 - 2015 257
• Figure 22-3: Market Drivers and Limiters in the PVMR Market, U.S., 2008 260
• Figure 22-4: Market Players, Potential Market for PMVR Devices, U.S., 2010 - 2015 262

PERCUTANEOUS AORTIC HEART VALVE REPLACEMENT DEVICES 263

• Figure 23-1: Potential Market for Aortic Valve Replacement Devices, Weighted Average Scenario, U.S., 2008 - 2015 265
• Figure 23-2: Total Revenue, Potential Market for Aortic Valve Replacement Devices, Weighted Average Scenario, U.S., 2011 - 2015 266
• Figure 23-3: Market Drivers and Limiters in the Aortic Valve Replacement Market, U.S., 2008 269
• Figure 23-4: Market Players, Potential Market for PAVR Devices, U.S., 2010 - 2015 272

ABBREVIATIONS 273

LIST OF CHART S

EXECUTIVE SUMMARY 1

• Chart 1-1: Market for Interventional Cardiology Devices, U.S., 2008 1
• Chart 1-2: Market for Coronary Stents, U.S., 2005 - 2015 1
• Chart 1-3: Coronary Atherectomy Devices Market, U.S., 2005 - 2015 3
• Chart 1-4: Coronary CTO Crosser Market, U.S., 2005 - 2015 4
• Chart 1-5: Coronary Vascular Closure Devices, U.S., 2005 - 2015 5
• Chart 1-6: Market for Diagnostic Coronary Catheters and Guidewires, U.S., 2005 - 2015 6
• Chart 1-7: Penetration Rate of FFR Guidewires in PCI Procedures, U.S., 2005 - 2015 7
• Chart 1-8: Number of IVUS Catheter Units Sold, U.S., 2005 - 2015 8
• Chart 1-9: Optical Coherence Tomography Catheter Market, U.S., 2010 - 2015 9
• Chart 1-10: Leading Competitors, Market for Interventional Cardiology, U.S., 2008 11

RESEARCH METHODOLOGY 12

U.S. MARKET FOR INTERVENTIONAL CARDIOLOGY DEVICES 23

• Chart 3-1: Market for Interventional Cardiology, U.S., 2005 - 2015 24
• Chart 3-2: Market for Interventional Cardiology Segmented by Device Type, U.S., 2008 28
• Chart 3-3: Market for Interventional Cardiology Segmented by Device Type, U.S., 2015 29
• Chart 3-4: Trend Analysis for Selected Markets for Interventional Cardiology Devices, U.S., 2005 - 2015 33
• Chart 3-5: Leading Competitors, Market for Interventional Cardiology, U.S., 2008 39

BARE-METAL AND DRUG-ELUTING STENTS 43

• Chart 4-1: Population at Risk, Market for Interventional Cardiology, U.S., 2005 - 2015 47
• Chart 4-2: Age Group Most Likely to Undergo Cardiac Intervention: 60 to 69 Years Old, U.S., 2005 - 2015 48
• Chart 4-3: Angioplasty and Angiography Procedures, U.S., 2005 - 2015 50
• Chart 4-4: Market for Coronary Stents by Type, U.S., 2005 - 2015 53
• Chart 4-5: Coronary Stent Units by Type, U.S., 2005 - 2015 55
• Chart 4-6: Market for Bare-Metal Stents, U.S., 2005 - 2015 57
• Chart 4-7: Market for Drug-Eluting Stents, U.S., 2005 - 2015 62
• Chart 4-8: Penetration Rate for Bioabsorbable Stents, U.S., 2013 - 2015 68
• Chart 4-9: Penetration Rate for Bifurcated Stents, U.S., 2010 - 2015 70
• Chart 4-10: Market for Coronary Stents by Delivery Platform, Units Sold, U.S., 2005 - 2015 72
• Chart 4-11: Market for Coronary Stents by Size, U.S., 2008 74
• Chart 4-12: Leading Competitors, Market for Bare-Metal Stents, U.S., 2008 76
• Chart 4-13: Leading Competitors, Market for Drug-Eluting Stents, U.S., 2008 80

PTCA AND CUTTING BALLOON CATHETERS 84

• Chart 5-1: Market for PTCA and Cutting Balloon Catheters, U.S., 2005 - 2015 86
• Chart 5-2: Market for PTCA Balloon Catheters, U.S., 2005 - 2015 89
• Chart 5-3: Market for Cutting Balloon Catheters, U.S., 2005 - 2015 92
• Chart 5-4: Leading Competitors, Market for PTCA Balloon Catheters, U.S., 200896

BALLOON-INFLATION SYRINGES 98

• Chart 6-1: Market for Balloon-Inflation Syringes, U.S., 2005 - 2015 100
• Chart 6-2: Leading Competitors, Market for Balloon-Inflation Syringes, U.S., 2008 103

ANGIOPLASTY KITS 104

• Chart 7-1: Market for Angioplasty Accessory Kits, U.S., 2005 - 2015 106
• Chart 7-2: Leading Competitors, Market for Angioplasty Accessory Kits, U.S., 2005 - 2015 109

INTERVENTIONAL CATHETERS 110

• Chart 8-1: Market for Interventional Coronary Catheters by Device Type, U.S., 2005 - 2015 113
• Chart 8-2: Leading Competitors, Market for Interventional Coronary Catheters, U.S., 2008 119

INTERVENTIONAL GUIDEWIRES 120

• Chart 9-1: Units Sold, Market for Interventional Coronary Guidewires, U.S., 2005 - 2015 122
• Chart 9-2: Market for Interventional Coronary Guidewires by Device Type, U.S., 2005 - 2015 124
• Chart 9-3: Leading Competitors, Market for Interventional Coronary Guidewires, U.S., 2008 129

EMBOLIC PROTECTION DEVICES 130

• Chart 10-1: Market for Coronary Embolic Protection Devices, U.S., 2005 - 2015133
• Chart 10-2: Leading Competitors, Market for Coronary Embolic Protection Devices, U.S., 2008 139

CORONARY ATHERECTOMY DEVICES 140

• Chart 11-1: Market for Coronary Atherectomy Devices, U.S., 2005 - 2015 143
• Chart 11-2: Leading Competitors, U.S. Market for Coronary Atherectomy Devices, 2008 148

THROMBECTOMY DEVICES 149

• Chart 12-1: Market for Coronary Thrombectomy Devices, U.S., 2005 - 2015 151
• Chart 12-2: Leading Competitors, Market for Coronary Thrombectomy Devices, U.S., 2008 155

CHRONIC TOTAL OCCLUSION CROSSERS 156

• Chart 13-1: Market for Coronary Chronic Total Occlusion Crossers, U.S., 2005 - 2015 159
• Chart 13-2: Penetration Rate, Market for Coronary Chronic Total Occlusion Crossers, U.S., 2005 - 2015 161
• Chart 13-3: Leading Competitors, Market for Coronary Chronic Total Occlusion Crossers, U.S., 2008 165

INTRODUCER SHEATHS 166

• Chart 14-1: Coronary Market for Introducer Sheaths, U.S., 2005 - 2015 169
• Chart 14-2: Leading Competitors, U.S. Market for Introducer Sheaths, 2008 172

VASCULAR CLOSURE DEVICES 173

• Chart 15-1: Market for Coronary Vascular Closure Devices (Invasive and Non-Invasive), U.S., 2005 - 2015 175
• Chart 15-2: Leading Competitors, Market for Coronary Vascular Closure Devices, U.S., 2008 182

DIAGNOSTIC CATHETERS AND GUIDEWIRES 183

• Chart 16-1: Market for Diagnostic Coronary Catheters and Guidewires, U.S., 2005 - 2015 185
• Chart 16-2: Market for Diagnostic Coronary Catheters, U.S., 2005 - 2015 187
• Chart 16-3: Units Sold Segmented by Size, Market for Diagnostic Coronary Catheters, U.S., 2005 - 2015 190
• Chart 16-4: Leading Competitors, Market for Diagnostic Coronary Catheters, U.S., 2008 192
• Chart 16-5: Market for Diagnostic Coronary Guidewires, U.S., 2005 - 2015 194
• Chart 16-6: Leading Competitors, Market for Diagnostic Coronary Guidewires, U.S., 2008 197
• Chart 16-7: Market for FFR Guidewires, U.S., 2005 - 2015 199
• Chart 16-8: Leading Competitors in the FFR Guidewire Market, U.S., 2008 202

IVUS CATHETERS 204

• Chart 17-1: Market for IVUS Catheters, U.S., 2005 - 2015 207

OPTICAL COHERENCE TOMOGRAPHY (OCT) DEVICES 212

• Chart 18-1: Potential Market for OCT Catheters, U.S., 2010 - 2015 216

VULNERABLE PLAQUE DEVICES 222

• Chart 19-1: Target Population, Potential Market for Vulnerable Plaque Screening, U.S., 2005 - 2015 227
• Chart 19-2: Maximum Potential Market for Vulnerable Plaque, U.S., 2010 - 2015 229
• Chart 19-3: Forecasted Potential Market for Vulnerable Plaque, U.S., 2010 - 2015 231
• Chart 19-4: Forecasted Potential Market for Vulnerable Plaque Screening, U.S., 2010 - 2015 233
• Chart 19-5: Forecasted Potential Market for Vulnerable Plaque Treatment, U.S., 2010 - 2015 235

PFO DEVICES 240

• Chart 20-1: Market for PFO Devices, U.S., 2005 - 2015 242
• Chart 20-2: Leading Competitors, Market for PFO Devices, U.S., 2008 247

ASD AND VSD DEVICES 248

• Chart 21-1: Market for ASD and VSD Devices, U.S., 2005 - 2015 250
• Chart 21-2: Leading Competitors in the ASD and VSD Market, U.S., 2008 254

PERCUTANEOUS MITRAL VALVE REPAIR DEVICES 255

• Chart 22-1: Potential Market for Percutaneous Mitral Valve Repair Devices, U.S., 2010 - 2015 258

PERCUTANEOUS AORTIC HEART VALVE REPLACEMENT DEVICES 263

• Chart 23-1: Revenue Probability, Potential Market for Aortic Valve Replacement Devices, U.S., 2008 - 2015 267

ABBREVIATIONS 273