Abstract
Summary
This report describes and evaluates animal biotechnology and its application
in veterinary medicine and pharmaceuticals as well as improvement in food
production. Knowledge of animal genetics is important in the application of
biotechnology to manage genetic disorders and improve animal breeding.
Genomics, proteomics and bioinformatics are also being applied to animal
biotechnology.
Transgenic technologies are used for improving milk production and the meat in
farm animals as well as for creating models of human diseases. Transgenic
animals are used for the production of proteins for human medical use.
Biotechnology is applied to facilitate xenotransplantation from animals to
humans. Genetic engineering is done in farm animals and nuclear transfer
technology has become an important and preferred method for cloning
animals.There is discussion of in vitro meat production by culture
Biotechnology has potential applications in the management of several animal
diseases such as foot-and-mouth disease, classical swine fever, avian flu and
bovine spongiform encephalopathy. The most important biotechnology-based
products consist of vaccines, particularly genetically engineered or DNA
vaccines. Gene therapy for diseases of pet animals is a fast developing area
because many of the technologies used in clinical trials humans were developed
in animals and many of the diseases of cats and dogs are similar to those in
humans.RNA interference technology is now being applied for research in
veterinary medicine
Molecular diagnosis is assuming an important place in veterinary practice.
Polymerase chain reaction and its modifications are considered to be
important. Fluorescent in situ hybridization and enzyme-linked immunosorbent
assays are also widely used. Newer biochip-based technologies and biosensors
are also finding their way in veterinary diagnostics.
Biotechnology products are approved by the Center for Veterinary Medicine of
the FDA. Regulatory issues relevant to animal biotechnology are described.
Approximately 109 companies have been identified to be involved in animal
biotechnology and are profiled in the report. These are a mix of animal
healthcare companies and biotechnology companies.Information is given about
the research activities of 11 veterinary and livestock research institutes.
Important 110 collaborations in this area are shown.
Share of biotechnology-based products and services in 2008 is analyzed and the
market is projected to 2018.
The text is supplemented with 33 tables and 5 figures.Selected 250 references
from the literature are appended.
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