Vaccines: The World Market

Table of Contents

Chapter One: Executive Summary

• Scope And Methodology
• Overview
• Pediatric Preventative Vaccines
  • The Market
• Adult Preventative Vaccines
  • The Market
• Total Preventative Market
• Emerging Cancer Vaccines
  • The Market
• Issues and Trends

Chapter Two: Introduction to Vaccines

• A Brief History: The Development of Vaccines
• The Immune Response
• Mechanism of Action
• Types of Vaccines
  • Attenuated (Weakened) Live Viruses
  • Killed (Inactivated) Viruses
  • Toxoid Vaccines
  • Genetically Engineered/Modified Vaccines
• Vaccine Approval Process

Chapter Three: Pediatric Preventive Vaccines

• Introduction
• Childhood Immunization in the United States
  • Childhood Immunization Rates
  • Challenges to the Vaccine Delivery System
  • Recommended Childhood Immunization Schedule
• Pediatric Vaccine Products
  • BCG Vaccines
  • Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio Vaccines
  • Haemophilus Influenzae Type B Vaccines
  • Hepatitis A Vaccines
  • Measles, Mumps and Rubella Vaccines
  • Pneumococcal Conjugate Vaccine
  • Rotavirus Vaccines
  • Varicella Vaccines
• Cost of Vaccines in the United States
• Pediatric Vaccines in Development
  • Global Initiatives for Vaccine Research
  • Diarrhea-Related Diseases
  • Acute Respiratory Infections
  • Other Conditions
• The World Market for Pediatric Preventive Vaccines
  • Total Market Size and Forecast
  • DTP and DTaP Vaccine Market
  • Hepatitis Vaccine Market
  • Haemophilus Influenzae Type B Vaccine Market
  • Measles, Mumps and Rubella Vaccines
  • Combination Vaccines Market
  • Pneumococcal Vaccine
  • Poliovirus Vaccine
  • Varicella Vaccines
  • Other Vaccines Market

Chapter Four: Adult Preventive Vaccines

• Introduction
• Adult Vaccine-Preventable Diseases: Facts and Figures
• Global Virological Surveillance Program
• Recommendations for Adult Immunizations
  • Vaccine Recommendations for International Travel
  • CDC' s Recommendations for Yellow Fever Vaccination
  • WHO International Health Regulations
• Adult Vaccine Products
  • BCG Vaccines
  • Cholera Vaccines
  • Diphtheria-Tetanus Vaccines
  • Hepatitis Vaccines
  • Influenza Vaccines
  • Japanese Encephalitis Vaccine
  • Pneumococcal Disease Vaccines
  • Rabies Vaccine
  • Typhoid Vaccines
  • Yellow Fever Vaccines
• Adult Vaccines in Development
• Global Initiatives for Vaccine Research
  • Cholera
  • Dengue Fever
  • Epstein-Barr Virus
  • HIV/AIDS
  • Helicobacter Pylori
  • Hepatitis
  • Herpesvirus
  • Leishmaniasis
  • Malaria
  • Severe Acute Respiratory Syndrome
  • Shigella
  • West Nile Virus
• The World Market for Adult Preventive Vaccines
  • Total Market Size and Forecast
  • Hepatitis Market
  • Influenza Vaccine Market
  • Travel, DT, and Miscellaneous Vaccine Market

Chapter Five: Preventive Vaccines Market Summary

• Trends Driving the Preventive Vaccines Market
• Market Size and Forecast
  • Vaccine Market Competitors
  • Pediatric Vaccines
  • Adult Vaccines

Chapter Six: Emerging Cancer Vaccines

• History and Growth of the Cancer Treatment Market
• Cancer Vaccine Technology
  • Antigen/Adjuvant Vaccines
  • Whole Cell Tumor Vaccines
  • Dendritic Cell (DC) Vaccines
  • Viral Vectors and DNA Vaccines
  • Idiotype Vaccines
  • Types of Therapeutic Vaccines
• Cancer Statistics
• Available Cancer Vaccines
  • Bladder Cancer
  • Cervical Cancer
  • Colorectal Cancer
  • Melanoma
• Types of Cancers Susceptible to Vaccines
  • Breast Cancer
  • Gastrointestinal Cancer
  • Kidney
  • Leukemia
  • Lung Cancer
  • Lymphoma
  • Multiple Myeloma
  • Neuroblastoma
  • Ovarian Cancer
  • Prostate Cancer
  • Sarcoma
• Cancer Vaccine Pipeline
  • Colorectal Cancer
  • Lung Cancer
  • GV-1001
  • Lymphoma
  • Melanoma
  • Prostate Cancer
  • Other Cancers
  • Telomerase
• The Emerging Cancer Vaccine Market
  • Total Market Size and Forecast
  • Competitor Analysis

Chapter Seven: Issues and Trends

• Vaccine Safety
  • Pre-licensure Evaluation
  • Post-Licensure Surveillance
  • The Vaccine Injury Compensation Program
  • World Health Organization
  • Other Initiatives
  • The Future of Vaccine Safety
• Vaccine Shortages
  • Preventing Future Shortages in the U.S.
  • Addressing Shortages in Developing Nations
• Preventing Pandemics
• Vaccines and Bioterrorism
  • Overview
  • Project Bioshield Act of 2004
  • National Bio and Agro-Defense Facility
  • Anthrax
  • Smallpox
  • Plague
  • Botulism
  • Tularemia
  • Viral Hemorrhagic Fevers
• Innovations in Vaccine Delivery Systems
  • Edible Vaccines
  • Mucosal Delivery
  • Intranasal Delivery
  • Oral Vaccines
  • Vaccine Patches

Chapter eight: Company Profiles

• Acambis plc
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• AlphaVax, Inc.
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
• Avant Immunotherapeutics
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Bavarian Nordic A/S
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Baxter Healthcare
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Berna Biotech AG
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Emergent biosolutions
  • History and Lines of Business
  • Strategic Acquisition and Alliance
  • Vaccine Products
  • Financial
• GlaxoSmithKline
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Medimmune
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Merck & Co. Inc
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Nabi Biopharmaceuticals
  • History and Lines of Business
  • Strategic Alliance
  • Vaccine Products
  • Financial Information
• Novartis
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Pfizer
  • History and Lines of Business
  • Vaccine products
  • Financial Information
• Pharmexa
  • History and Lines of Business
  • Vaccine Products
  • Financial Information
• Sanofi Pasteur
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
• Vical
  • History and Lines of Business
  • Strategic Alliances
  • Technology Platform
  • Therapeutic Cancer Vaccine Products in Clinical Trials
  • Financial Information
• Wyeth
  • History and Lines of Business
  • Vaccine Products
  • Financial Information

Appendix: Company Directory

LIST OF EXHIBITS

Chapter One: Executive Summary

• Figure 1-1: World Market Pediatric Vaccines by Current and Emerging Markets 2003-2012
• Figure 1-2: World Market Adult Vaccines by Current and Emerging Markets 2003-2012
• Figure 1-3: World Market Cancer Vaccines by Current and Emerging Markets 2003-2012

Chapter Two: Introduction to Vaccines

• Table 2-1: Impact of Vaccines in the 20th Century Annual Morbidity in the 20th Century vs 2005
• Table 2-2: Vaccine-Preventable Diseases

Chapter Three: Pediatric Preventive Vaccines

• Table 3-1: Global Immunization Rates by Vaccine Type 2005
• Table 3-2 : Immunization Profile of the United States: Population by Age Group, Number of Vaccine-Preventable Diseases Reported by Disease 1999-2005
• Table 3-3: U.S. Recommended Childhood Immunization Schedule, 2006
• Table 3-4: Cost of Vaccines: Private Sector Versus Public Sector Prices Last Reviewed/Updated, September 2006 (Vaccine, Brand Name, Packaging, CDC Cost/Dose, Private Sector Cost/Dose, Contract End Date, Manufacturer)
• Table 3-5: Selected Pediatric Vaccines in Development (Company, Product Name, Indication, Development Status)
• Table 3-6: World Market for Pediatric Vaccines by Type (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others)
• Figure 3-1: Market Share of Pediatric Vaccines by Type 2005
• Figure 3-2: Market Share of Pediatric Vaccines, by Type 2012
• Table 3-7: World DTP and DTaP Vaccine Market 2003-2012
• Table 3-8: World Pediatric Hepatitis Vaccine Market 2003-2012
• Table 3-9: World Hib Vaccine Market, 2003-2012
• Table 3-10: World MMR Vaccines Market 2003-2012
• Table 3-11: World Combination Vaccines Market 2003-2012
• Table 3-12: World Pediatric Pneumococcal Vaccine Market 2003-2012
• Table 3-13: World Poliovirus Vaccine Market 2003-2012
• Table 3-14: World Varicella Vaccine Market 2003-2012
• Table 3-15: Other Vaccines Market 2003-2012

Chapter Four: Adult Preventive Vaccines

• Table 4-1: Universal Adult Immunization Schedule 2006
• Table 4-2: Adult Immunization Schedule for Populations with Special Medical Conditions, 2006
• Table 4-3 : Selected Adult Preventive Vaccines in Development, 2007 (Company, Product Name, Indication, Development Status)
• Table 4-4: World Market for Adult Preventive Vaccines by Type (Hepatitis, Influenza, Pneumococcal, Travel/DT/Misc.), 2003-2012
• Figure 4-1: Market Share of Adult Vaccines, by Type, 2005
• Figure 4-2: Market Share of Adult Vaccines, by Type, 2012
• Table 4-5: World Hepatitis Vaccine Market 2003-2012
• Table 4-6: World Influenza Vaccine Market 2003-2012
• Table 4-7: U.S. Influenza Vaccination Rates by Age and Risk Group 2004 - 2005
• Table 4-8: CDC Goal to Double Flu Immunization by 2010 Group and Estimated Immunization Rate (2000 vs 2010)
• Table 4-9: 2005 Estimated Population by Region and Selected Age Group Population
• Table 4-10: World Pneumococcal Vaccine Market 2003-2012

Chapter Five: Preventive Vaccines Market Summary

• Figure 5-1: World Travel; Diphtheria-Tetanus; Miscellaneous Vaccines Market
• Table 5-1: The World Vaccines Market by Vaccine Type 2003-2012
• Figure 5-2: World Market for Vaccines Share by Type, 2003, 2007 and 2012
• Table 5-2: Major Manufacturers' Shares of the World Vaccine Market, 2005
• Figure 5-3: 2005 World Vaccines Market Share, by Leading Competitors
• Table 5-3: Major Manufacturer' s Shares of the World Pediatric Vaccine Market 2005
• Figure 5-5: Market Share of Pediatric Vaccines Market, 2005
• Table 5-4: Major Manufacturer' s Shares of the World Adult Vaccine Market 2005
• Figure 5-6: Market Share of Adult Vaccines Market 2005

Chapter Six: Emerging Cancer Vaccines

• Table 6-1: Estimated and Projected World Cancer Incidence by Selected Types of Cancer (Lung, Breast, Colon/Rectum, Stomach, Liver, Prostate, Cervix, Esophogus, Lymphoma, Pancreas, Melanoma), 2005 and 2020
• Figure 6-1: Estimated and Projected World Cancer Incidence by Selected Types of Cancer, 2005 and 2020
• Table 6-2: Estimated and Projected World Cancer Mortality by Selected Types of Cancer (Lung, Breast, Colon/Rectum, Stomach, Liver, Prostate, Cervix, Esophogus, Lymphoma, Pancreas, Melanoma), 2005 and 2020
• Figure 6-2: Estimated and Projected World Cancer Mortality by Selected Types of Cancer
• Table 6-3: Total Cancer Incidence by Sex and Country, 2006 Estimates (in thousands)
• Table 6-4: Estimated Cancer Incidence by World Region and Type of Cancer
• Figure 6-4: Estimated Cancer Incidence by World Regions
• Table 6-5: Malignant Conditions of the Skin
• Table 6-6: Types of Primary Lung Cancer, Risk Factors, Percent of Cases
• Table 6-7: Selected Cancer Vaccines in the Pipeline (Product Name, Developer, Indication, Development Phase, Earliest Approval Date)
• Table 6-8: World Market Cancer Vaccines by Cancer Type (Cervical, Colon/Rectal, Lung, Melanoma, Prostate, Other) 2003-2012
• Figure 6-5: Share of the Cancer Vaccine by Vaccine Indication, 2012

Chapter Seven: Issues and Trends

• Table 7-1: Selected Companies/Laboratories Developing Biodefense Vaccines