Drug Delivery Series I-IV (Oral, Implantable/Injectable, Pulmonary and Transdermal/Transmucosal Systems)

Table of Contents

Drug Delivery Markets, Vol I: Oral Delivery

CHAPTER one: Executive Summary

• Market Drivers
• Market Size and Growth
  • Total Oral Drug Delivery Market
  • Oral Drug Delivery Technology Only Market
• Competitive and Market Analysis

CHAPTER two: Introduction and Overview

• Scope of the Report
• Methodology
• History of Oral Drug Delivery
• Phases of Drug Action
• Barriers to Oral Drug Delivery
• Controlled-Release/Sustained-Release
• Delayed Release and Modified Release
• Fast Dissolving
• Taste-Masked
• Pulsatile Release
• Microemulsion and Others

CHAPTER three: Key Trends and Demographics

• The Elderly
• Regulatory Environment
• Patent Protection and Extension
• Earlier Involvement
• Consolidation
• Proprietary Product Development
• Implications for Generic and Over-the-Counter Products
• Pharmaceutical Formulation

CHAPTER four: New Developments

• Macromolecule Delivery
• Delivery of Hydrophobic Drugs
• Other Delivery Solutions

CHAPTER five: Market Size and Growth

• The Total Oral Drug Delivery Market
• Oral Delivery Technology Only Market

CHAPTER six: Competitive Analysis

• Competitive Landscape

CHAPTER seven: Company Profiles

• ALZA Corporation
• Andrx Pharmaceuticals
• Biovail Corporation
• Cardinal Health
• Elan Corporation, plc
• Emisphere Technologies, Inc.
• KV Pharmaceutical
• Labopharm, Inc.
• Penwest Pharmaceutical Company
• Purdue/MundiPharma/Napp Group
• SkyePharma PLC

CHAPTER eight: Companies in Brief

• Alkermes, Inc.
• Astellas
• BioProgress Technologies International, Inc.
• CIMA Labs, Inc. Division of Cephalon
• DepoMed, Inc.
• Endorex, Inc.
• Eurand, Inc.
• Kos Pharmaceuticals, Inc.
• Lipocine, Inc.

Appendix: Company Directory

List of Exhibits

CHAPTER one: Executive Summary

CHAPTER two: Introduction and Overview

• Table 2-1: Selected Types of Oral Solid Preparations
• Table 2-2: Sequence of Drug Action

CHAPTER three: Key Trends and Demographics

• Table 3-1: World Population by Age Group 2002-2010
• Figure 3-1: World Population by Age Group 2002-2010
• Table 3-2: Recent Consolidations in the Drug Delivery Market

CHAPTER four: New Developments

CHAPTER five: Market Size and Growth

• Table 5-1: The Worldwide Market for Oral Drug Delivery Technology and Pharmaceuticals Revenues and Growth Rate 2002-2010
• Figure 5-1: Trending in the Worldwide Market for Oral Drug Delivery Technology and Pharmaceuticals 2002-2010
• Table 5-2: The Worldwide Market for Pharmaceuticals Utilizing Oral Drug Delivery Technologies by Type 2002-2010
• Figure 5-2: Trending in the Worldwide Market for Pharmaceuticals Utilizing Oral Drug Delivery Technologies by Type 2002-2010
• Table 5-3: The Worldwide Market for Pharmaceuticals Utilizing Oral Drug Market Share by Type 2002-2010
• Table 5-4: The Worldwide Market for Oral Drug Delivery Systems by Pharmaceutical vs Drug Delivery Components 2002-2010
• Table 5-5: The Worldwide Market for Oral Drug Delivery Systems Distribution of Revenue by Pharmaceutical vs Drug Delivery Component 2002-2010
• Figure 5-3: The Worldwide Market for Oral Drug Delivery Systems Share of Revenue by Pharmaceutical and Drug Delivery Component 2006, 2010

CHAPTER six: Competitive Analysis

• Table 6-1: Leading Suppliers of Oral Drug Delivery Technology (Company, Proprietary Technology, Approved Products)

Drug Delivery Markets, 2nd Edition, Vol II: Implantable / Injectable Delivery Systems

CHAPTER one: Executive Summary

• Market Drivers
• Market Size and Growth
  • Total Injectable/Implantable Drug Delivery Market
  • The Injectable/Implantable Drug Delivery Only Market
• Competitor and Market Analysis

CHAPTER two: Introduction

• Scope and Methodology
• Reasons for Injectable/Implantable Drug Delivery Systems
• History of Injectable/Implantable Drug Delivery
• Phases of Drug Action
• Needle-Free Drug Delivery
  • Major Applications
  • Safety Concerns
  • Products
• Implantable Drug Delivery
  • Mechanisms
  • Applications
  • Products
• Sustained-Release Drug Delivery
  • Products
• Targeted Injection Drug Delivery
  • Products

CHAPTER three: Trends and Developments

• Drivers of the Injectable/Implantable Drug Delivery Market
  • Biologics
  • Cancer
• Pen injectors
• Proprietary Product Development
• Delivery Systems Placement Trends
• Therapeutic Trends
• Incorporation of Technology
• Nanotechnology
• Drug Delivery Development
  • Microsphere Technology
  • Targeted Technology
  • MicroChip Technology
  • NanoParticles
  • Protein-Coated Microcrystal Technology
  • Needle-Free Delivery Development
  • Selected Products in Development

CHAPTER four: Market Size and Growth

• The Total Injectable/Implantable Drug Delivery Market
• Injectable/Implantable Delivery Technology Only Market

CHAPTER five: Competitive and Market Analysis

• Competitive Landscape
• Market Analysis

CHAPTER six: Company Profiles

• Alkermes, Inc.
• ALZA Corp.
• Antares Pharma, Inc.
• Bioject Medical Technologies, Inc.
• CyDex, Inc.
• MGI Pharma, Inc
• Nektar Therapeutics
• PowderMed Pharmaceuticals Plc
• SkyePharma Plc
• Zogenix Corporation

CHAPTER seven: Companies in Brief

• AP Pharma
• Baxter BioPharma Solutions
• ImaRx Therapeutics Inc.
• PR Pharmaceuticals, Inc.
• pSivida
• QLT USA, Inc

Appendix: Company Directory

TABLE OF EXHIBITS

CHAPTER one: Executive Summary

• Figure 1-1: The Worldwide Market for Injectable/Implantable
• Drug Delivery Technology and Pharmaceuticals 2002-2010

CHAPTER two: Introduction

• Table 2-1: Sequence of Drug Action

CHAPTER three: Trends and Developments

• Table 3-1: Select Products in Early Stage Development by Drug
• Delivery Companies

CHAPTER four: Market Size and Growth

• Table 4-1: Worldwide Market for Injectable/Implantable Drug Delivery Technology and Pharmaceuticals 2002-2010
• Figure 4-1: Worldwide Market for Injectable/Implantable Drug Delivery Technology and Pharmaceuticals 2002-2010
• Table 4-2: Worldwide Market for Pharmaceuticals Utilizing Injectable/ Implantable Drug Delivery by Type 2002-2010
• Figure 4-2: Worldwide Market for Pharmaceuticals Utilizing Injectable/ Implantable Drug Delivery by Type 2002-2010
• Table 4-3: Worldwide Market for Pharmaceuticals Utilizing Injectable/ Implantable Drug Delivery Market Share by Type 2002-2010
• Figure 4-3: Worldwide Market for Pharmaceuticals Utilizing Injectable/ Implantable Drug Delivery Market Share by Type 2006
• Figure 4-4: Worldwide Market for Pharmaceuticals Utilizing Injectable/ Implantable Drug Delivery Market Share by Type 2010
• Table 4-4: Worldwide Market for Injectable/Implantable Drug Delivery Systems by Pharmaceutical and Drug Delivery Component 2002-2010
• Table 4-5: Injectable/Implantable Drug Delivery Systems: Worldwide Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2002-2010
• Figure 4-5: Injectable/Implantable Drug Delivery Systems Worldwide Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2006
• Figure 4-6: Injectable/Implantable Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2010

CHAPTER five: Competitive and Market Analysis

• Table 5-1: Leading Suppliers of Injectable/Implantable Drug Delivery Technology
• Figure 5-1: Cost per Million Injections by Injector Type

Drug Delivery Markets, Vol III: Pulmonary Delivery Systems

CHAPTER one: Executive Summary

• Market Drivers
• Market Size and Growth
• The Total Pulmonary Drug Delivery Market
• The Total Pulmonary Drug Delivery Only Market
• Competitor and Market Analysis

CHAPTER two: Introduction and Overview

• Scope and Methodology
• Reasons for pulmonary Drug Delivery Systems
• History and Mechanics of Pulmonary Drug Delivery
• Phases of Drug Action
• Pharmacokinetics of Inhalation
• Inhalation Delivery Technologies
• Metered Dose Inhalers
• Dry Powder Formulations
• Nebulizer Delivery Formulations
• Liquid Formulations
• Nanospheres
• Intranasal Delivery Technologies

CHAPTER three: Trends and Demographics

• Asthma
• Opportunities for Drug Delivery System Success
• Exubera Breakthrough
• Nano and Microparticulate Systems
• Trends in Liquid Aerosols
• CFC Phase Out
• Expansion of Biotechnology
• Macromolecule Delivery

CHAPTER four: New Developments

• Prodrug Drug Delivery
• Electrohydrodynamic Aerosol Delivery
• Oxygen Delivery
• Crystallization Technology

CHAPTER five: Market Size and Growth

• The Total Pulmonary Drug Delivery Market
• Pulmonary Delivery Technology Only Market

CHAPTER six: Competitive and Market Analysis

• Competitor Analysis
• Market Analysis

CHAPTER seven: Company Profiles

• 3M Pharmaceuticals
• Alkermes, Inc.
• Aradigm Corporation
• Elan Corporation, Plc
• Innovata BioMed Plc
• MicroDose Technology, Inc
• Nastech Pharmaceutical Company Inc.
• Nektar Therapeutics
• Oriel Therapeutics
• Pipex Pharmaceuticals
• Resiprics, Inc.
• SkyePharma Plc
• Vectura Ltd.
• Ventaira Pharmaceuticals, Inc.

CHAPTER eight: Companies in Brief

• Bespak
• Direct Haler A/S
• IntraNasal Therapeutics

Appendix: Company Directory

TAble of exhibits

CHAPTER one: Executive Summary

• Table 1-1: The Worldwide Market for Pulmonary Drug Delivery Technology and Pharmaceuticals 2002-2010
• Figure 1-1: The Worldwide Market for Pulmonary Drug Delivery Technology and Pharmaceuticals 2002-2010
• Table 1-2: The Worldwide Market for Pulmonary Drug Delivery Systems by Pharmaceutical and Drug Delivery Component 2002-2010
• Figure 1-2: The Worldwide Market for Pulmonary Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2002-2010

CHAPTER two: Introduction and Overview

• Table 2-1: Sequence of Drug Action

CHAPTER three: Trends and Demographics

• Table 3-1: Worldwide Prevalence of Asthma 2006
• Figure 3-1: Worldwide Prevalence of Asthma 2006
• Table 3-2: World Population by Age Group 2002-2010
• Figure 3-2: World Population by Age Group 2002-2010

CHAPTER five: Market Size and Growth

• Table 5-1: The Worldwide Market for Pulmonary Drug Delivery Technology and Pharmaceuticals 2002-2010
• Figure 5-1: The Worldwide Market for Pulmonary Drug Delivery Technology and Pharmaceuticals 2002-2010
• Table 5-2: The Worldwide Market for Pharmaceuticals Utilizing Pulmonary Drug Delivery Systems by Type 2002-2010
• Figure 5-2: The Worldwide Market for Pharmaceuticals Utilizing Pulmonary Drug Delivery Systems Revenues by Type 2002-2010
• Table 5-3: The Worldwide Market for Pharmaceuticals Utilizing Pulmonary Drug Delivery Technologies Market Share by Type 2002-2010
• Figure 5-3: The Worldwide Market for Pharmaceuticals Utilizing Pulmonary Drug Delivery Technologies by Type 2006
• Figure 5-4: The Worldwide Market for Pharmaceuticals Utilizing Pulmonary Drug Delivery Technologies by Type 2010
• Table 5-4: The Worldwide Market for Pulmonary Drug Delivery Systems by Pharmaceutical and Drug Delivery Component 2002-2010
• Table 5-5: of Revenue by Pharmaceutical and Drug Delivery Component 2002-2010
• Figure 5-5: of Revenue by Pharmaceutical and Drug Delivery Component 2002-2010
• Figure 5-6: The Worldwide Market for Pulmonary Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2006
• Figure 5-7: The Worldwide Market for Pulmonary Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2010

CHAPTER six: Competitive and Market Analysis

• Table 6-1: Selected Leading and Emerging Suppliers of Pulmonary Drug
• Delivery Technology

Drug Delivery Markets, Vol. IV: Transdermal

CHAPTER One: Executive Summary

• Market Drivers
• Market Size and Growth
  • Total Transdermal/Transmucosal Drug Delivery Market
  • Transdermal/Transmucosal Drug Delivery Only Market
  • Competitive and Market Analysis

CHAPTER Two: Introduction and Overview

• Scope and Methodology
• Reasons for Transdermal/Transmucosal Drug Delivery Systems
• History of Transdermal and Transmucosal Drug Delivery
• Phases of Drug Action
• Topical Drug Delivery
  • Types of Topical Preparations
  • Market Participants
  • Transdermal Patch Drug Delivery
    • Membrane-Controlled System
    • Adhesive Dispersion-Type System
    • Matrix Diffusion-Controlled System
    • Microreservoir Dissolution-Controlled System
    • New Transdermal Drug Applications and Approvals
    • Electrotransport Drug Delivery
    • Iontophoresis
    • Transmucosal Drug Delivery
      • Oral Transmucosal Fentanyl Citrate (OTFC)
      • Transmucosal Etomidate
      • Ondansetron ODT
      • Buccal Drug Delivery
      • Vaginal Drug Delivery

CHAPTER three: Trends and Developments

• Innovations in Transdermal Drug Delivery
• Adhesive Technology and Issues
• Adhesive Market Issues
• Biotechnological Issues
• Iontophoresis and Sonophoresis
• Developments in Insulin Delivery
• New Developments in Hormone Drug Delivery
• New Mucosal/Buccal Delivery Systems
• Other New Drug Delivery Systems
• Macroflux Technology
• Controlled Thermal Energy Technology
• New Ultrasound Technology
• Combination Delivery Technology
• Transdermal Products in Development

CHAPTER four: Market Size and Growth

• The Total Transdermal/Transmucosal Drug Delivery Market
• Transdermal/Transmucosal Delivery Technology Only Market

CHAPTER five: Competitive Analysis

• Competitive Landscape
• Market Analysis

CHAPTER SIX: Company Profiles

• 3M Pharmaceuticals
• Acrux Limited
• Altea Therapeutics, Inc
• ALZA Corporation
• Antares Pharma, Inc.
• Aveva Drug Delivery Systems
• Cardinal Health
• Cephalon Inc
• Generex Biotechnology Corporation
• Inovio Biomedical Corporation
• Labtec GmbH
• Lohmann Therapy-Systems Corp (LTS Lohmann Therapie Systeme AG)
• MacroChem Corporation
• NexMed, Inc.
• Noven Pharmaceuticals, Inc.
• SkyePharma PLC

Appendix

Company Directory

Table of exhibits

CHAPTER twO: Introduction and Overview

• Table 2-1: Sequence of Drug Action

CHAPTER three: Trends and Developments

• Table 3-1: Selected Transdermal Products in Development

CHAPTER four: Market Size and Growth

• Table 4-1: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Technology and Pharmaceuticals 2002-2010
• Figure 4-1: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Technology and Pharmaceuticals 2002-2010
• Table 4-2: The Worldwide Market for Pharmaceuticals Utilizing Transdermal/ Transmucosal Drug Delivery Systems by Type 2002-2010
• Figure 4-2: The Worldwide Market for Pharmaceuticals Utilizing Transdermal/ Transmucosal Drug Delivery Systems Revenues by Type 2002-2010
• Table 4-3: The Worldwide Market for Pharmaceuticals Utilizing Transdermal/ Transmucosal Drug Delivery Technologies Market Share by Type 2002-2010.......
• Figure 4-3: The Worldwide Market for Pharmaceuticals Utilizing Transdermal/ Transmucosal Drug Delivery Technologies by Type 2006
• Figure 4-4: The Worldwide Market for Pharmaceuticals Utilizing Transdermal/ Transmucosal Drug Delivery Technologies by Type 2010
• Table 4-4: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Systems by Pharmaceutical and Drug Delivery Component 2002-2010
• Table 4-5: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2002-2010
• Figure 4-5: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2002-2010
• Figure 4-6: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2006
• Figure 4-7: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2010

CHAPTER five: Competitive Analysis

• Table 5-1: Leading Suppliers of Transdermal/Transmucosal Drug Delivery Technology