Table of Contents
1. Executive Summary
2. Introduction
- 2.1 Drug Addiction/Abuse/Dependency Definitions
- 2.2 The Development of Drugs Specifically for Treating Addiction
- 2.3 Maintenance Treatment is Controversial
- 2.4 Objectives, Methodology and Scope
3. The Physiology and Psychology of Addiction
- 3.1. Addiction Affects Many Areas of the Brain
- 3.2. Dopamine is Key
- 3.3. GABA Imbalance Incites Craving
- 3.4. The Psychology of Addiction
4. Regional Prevalence of Addiction
- 4.1 The Economic Cost of Addiction
- 4.2 Drug Dependency Low, But Severe Hazard
- 4.3 Alcohol Dependency Increasing Despite Health Consequences
- 4.4 Smoking Prevalence Causes Highest Fatality Rates From Dependency
- 5.5 Associated Problems Increase With Gambling Increase
5. Drug Addiction
- 5.1 Heroin - The Most Serious of all Addictions?
- 5.2 What Happens When Heroin is Taken?
- 5.2.1 Withdrawal Symptoms
- 5.3 Drug Addiction Treatments
- 5.3.1 Opioid Addiction Has Well Tried Treatments
- 5.4 Opioid Dependence Treatment Regimes
- 5.5 Naltrexone Implants Remain Expensive
- 5.6 Cocaine Addiction Looks To Future Success
- 5.7 Cocaine Treatment - A Vaccine Available Soon?
- 5.7.1 Drugs to reduce symptoms of cocaine abstinence or craving
- 5.8 Market Outlook For Drug Addiction Treatments
- 5.8.1 Cocaine Addiction Treatments Hold Greatest Promise
6. Alcohol Addiction
- 6.1 The Effects and Problems Associated With Alcohol
- 6.2 Alcohol dependency tests
- 6.3 Alcohol Addiction Treatments
- 6.3.1 Antabuse - Available Since 1948
- 6.3.2 Naltrexone Now Available in Injectable Form
- 6.4 Campral Offers Another Mode of Action for Alcohol Dependency Treatment
- 6.5 Most Recent Alcohol Dependency Drug From J&J
- 6.6 Serotonergic Agents Show Limited Usefulness
- 6.7 Drug treatment for related disorders
- 6.8 Market Outlook For Alcohol Dependency Treatments
7. Smoking Addiction
- 7.1 How to assess the level of nicotine addiction?
- 7.2 Smoking Addiction Treatments
- 7.2.1 Chantix is the Latest Anti-smoking Treatment
- 7.2.2 NRT Dominates Smoking Treatment Therapies
- 7.2.3 Zyban Provides Effective Treatment
- 7.3 Beneficial Effects Are Quickly Noticeable
- 7.4 Withdrawal Effects Are Also Quickly Noticeable
- 7.5 Market Outlook for Nicotine Dependency Treatments
- 8. Gambling Addiction
- 8.1 Gambling Addiction Treatments
- 8.1.1 Opioid Antagonists (OA)
- 8.1.2 Selective Serotonin Reuptake Inhibitors (SSRIs)
- 8.1.3 Mood Stabilisers
- 8.1.4 Other Pharmaceutical Treatment Options for Gambling Treatment
- 8.2 Market Outlook for Gambling Addiction Treatments
9. Obesity and Food Addiction
- 9.1 Obesity and Food Addiction Treatments
- 9.2 Will Acomplia Accomplish More?
- 9.3 Other Opportunities For Obesity Treatment
- 9.3.1 Hormone Treatment Greeted With Optimism
- 9.4 Market Outlook for Obesity Treatments
10. World Market by Region
- 10.1 Drivers and Restraints
- 10.2 The US Market Presents Considerable Opportunities
- 10.3 The Japanese Market May Accept Treatments on a Limited Scale
- 10.4 US Market Is Surprisingly Undeveloped For Addiction Treatments
11. Unmet Needs in Addiction Treatments
- 11.1 Pipeline Products for the Treatment of Drug Addiction
- 11.2 Fulcrum's Link With Celtic Could Produce Novel Addiction Therapies
- 11.3 Genetic Link Between Disorders Inspires Further Research
- 11.4 Drug addiction
- 11.4.1 Opioid Addiction
- 11.4.2 Cocaine Addiction
- 11.5 Alcohol Addiction
- 11.6 Smoking Addiction
- 11.7 Grants From the US NIDA Used to Develop Nicotine Vaccination
- 11.8 Gambling Addiction
- 11.9 Obesity Food Addiction - Huge Interest in Potentially Lucrative Market
12. Sanofi-Aventis: A Review
- 12.1 The Takeover of Aventis By Sanofi was Aggressive
- 12.2 Sanofi-Aventis Continues to Expand
13. Conclusion
Tables
- Table 5.1 A Comparison of the Heroin Dependency Treatment Options
- Table 7.1 Leading Available NRT Products
- Table 7.2 Beneficial Effects of Smoking Cessation
- Table 7.3 The Duration of Smoking Withdrawal Effects
- Table 7.4 World Revenue ($m) for Chantix, 2005-2011
- Table 9.1 World Revenue ($m) for Acomplia, 2005-2011
- Table 10.1 Leading Drugs For The Addiction Treatment Markets
- Table 10.2 World Revenue ($m) and Growth Rate (%) of the Obesity Treatment
Market, by Region, 2005
- Table 10.3 World Revenue ($m) and Growth Rate (%) of the Nicotine
Addiction Treatment Market, by Region, 2005
- Table 10.4 World Revenue ($m) and Growth Rate (%) of the Alcohol
Dependency Treatment Market, by Region, 2005
- Table 11.1 Pipeline Products For Anti-Drug Addiction Treatments
- Table 11.2 Pipeline Products for Cocaine Addiction Treatment
- Table 11.3 Pipeline Products for Alcohol Dependency Treatment
- Table 11.4 Pipeline Products for Obesity Treatment
- Table 11.5 Pipeline Products for Gambling Addiction
- Table 11.6 Selected Key Pipeline Products For Obesity Treatment
Figures
- Figure 1.1 World Revenue ($m) for Acomplia, 2005-2011
- Figure 6.1 Alcohol Consumption in Young Adults (18-29 years)
- Figure 6.2 Percentage of Children Aged 15-16 Drunk Over 20 Times in
Lifetime
- Figure 7.1 World Revenue ($m) for Chantix, 2005-2011
- Figure 9.1 World Revenue ($m) for Acomplia, 2005-2011
- Figure 10.1 Market Share (%) for Obesity Treatments by Region, 2005
- Figure 10.2 Market Share (%) for Nicotine Addiction Treatments by Region,
2005
- Figure 10.3 Market Share (%) for Nicotine Addiction Treatments by Region,
2005
Organisations Listed
- Abbott Laboratories
- Aktiv-Dry
- Alizyme
- Alkermes
- Alpharma
- Amgen
- Amylin
- Arena
- Britannia Pharmaceuticals
- BioTie Therapies
- British American Tobacco
- Celtic Pharma
- Cephalon
- Cetilistat
- Cytos Biotech
- DrugAbuse Sciences
- Eisai
- Forest
- Fujisawa
- Fulcrum Pharma
- GSK
- Hokuriku Seiyaku
- Hythiam
- INSERM
- Johnson & Johnson
- Lipha Pharmaceuticals
- Merck
- Merck KGaA
- Metabolic
- Nabi Pharmaceuticals
- Nastech
- New River Pharmaceuticals
- Nippon Shinyaku
- Novartis
- Peptimmune genzyme
- Pfizer
- Philip Morris
- Phytopharm
- Pliva
- Reckitt Benckiser
- Roche
- Sanofi-Aventis
- Schering-Plough
- Shionogi
- Shire
- Somaxon
- Titan Pharmaceuticals
- Unilever
- Valera
- Vernalis
- Xenova
- 7TM Pharma
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