Table of Contents
Chapter 1 Executive Summary
Chapter 2 Introduction - The Erectile Dysfunction Market Will See Large Growth Rates Throughout the Period, 2007-2012
- 2.1 The Viagra Revolution
- 2.2 Erectile Dysfunction Defined
- 2.3 ED Prevalence is Increasing
- 2.4 Male Hormonal Changes Due to Age
- 2.5 How an Erection Occurs
- 2.6 Penile Anatomy and Erection
- 2.7 Primary and Secondary ED
- 2.8 The Causes of Secondary ED
- 2.9 ED Due to Systemic Diseases and Ageing 2.10 Neurogenic Erectile
Dysfunction
- 2.11 Vascular Causes of Erectile Dysfunction
- 2.12 Drug-Induced Erectile Dysfunction
- 2.13 Summary of All ED Treatments
- 2.14 Drug Therapy
- 2.14.1 Mechanism of Action of PDE-5 Inhibitors
- 2.14.2 Viagra (Pfizer)
- 2.14.3 Cialis (Eli Lilly/Icos)
- 2.14.4 Levitra (GSK/Bayer AG)
Chapter 3 The World Market for ED Drugs
- 3.1 The ED Market Will See Large Growth Rates
- 3.2 Viagra Will Lose Dominance of the ED Market
- 3.3 Cialis Will Achieve Blockbuster Status
- 3.4 Viagra Will Lose Market Dominance to Cialis
- 3.5 Levitra Shows Strong Growth
- 3.6 Shortest Time to Erection is a Major Market Advantage
- 3.7 Brand Awareness Will Play a Key Part in Maintaining Viagra' s Position
in the Market
- 3.8 Brand Switching Will Increase Individual Drug Sales But Not Expand the
Market
- 3.9 Market Expansion Depends on Persuading ED Men to Seek Treatment 3.10
Pfizer Currently Leads the ED Market
- 3.11 The US Dominates the World Market for ED Drugs
Chapter 4 Forces Affecting the ED Market
- 4.1 SWOT Analysis of the ED Market
- 4.2 An Expanding Patient Population Constitutes the Principal Driver in
the ED Market
- 4.3 The Principal Restraints in the ED Market
- 4.4 Major Success in the ED Drugs Market and Opportunities to Target
- 4.5 Adverse Events Over ED Drugs
- 4.5.1 FDA Revise Label Changes to ED Drugs After Reported Sudden Hearing
& Vision Loss
- 4.5.2 FDA Immediately Recall "Natural" ED Drugs After Major Concerns
Over Safety
- 4.5.3 Studies Link ED to Heart Disease and Smoking
- 4.6 Lack of Adequate Reimbursement Limits Potential of ED Drugs
- 4.7 ED Surgery - A Last Resort When Drug-Based Treatments Fail
- 4.7.1 Penile Venous Surgery
- 4.7.2 Penile Arterial Revascularization
- 4.7.3 Penile Implants
- 4.7.4 Internal Penile Pump
- 4.8 ED Awareness is Key for Market Expansion
- 4.9 Uprima (Apomorphine) is a Market Failure
Chapter 5 Female Sexual Dysfunction (FSD) and Future Market Possibilities
- 5.1 Female Sexual Arousal
- 5.2 Over 45% of All Women Will Experience Some Degree of FSD
- 5.3 Genital Vascular Congestion Essential for Normal Sexual Function in
Both Men and Women
- 5.4 The Medical Causes of Female Sexual Dysfunction
- 5.5 Medical Drugs Can Cause FSD
- 5.6 There are Times in a Women' s Life of Natural Decreased Sexual Desire
- 5.7 The Treatments for Female Sexual Dysfunction
- 5.8 The Role of Estrogen and Progesterone in Female Sexual Desire is not
Understood
- 5.9 The Role of Testosterone in Female Sexual Desire is Not Clear 5.10 The
Treatment of Female Sexual Arousal Disorders
- 5.11 Anorgasmia Responds Well to Therapy
- 5.12 The Successful Treatment for Dyspareunia Approaches 90%
- 5.13 The Pharmacological Treatment of FSD and Future Market Possibilities
Chapter 6 Pipeline Developments in the Erectile Dysfunction Market
- 6.1 Abbott' s ABT- 670 in Phase I Trials for ED
- 6.2 Agents in Phase II of Clinical Development
- 6.2.1 Pfizer' s UK 369003
- 6.2.2 Inotek' s INO 1001
- 6.2.3 Schering-Plough' s Dasantafil
- 6.2.4 Vivus' Avanafil
- 6.2.5 Abbott' s ABT-724
- 6.3 SK Chemicals' Mirodenafil in Pre-Registration for ED
- 6.4 New Drugs for ED Must Have a Short Onset Time
- 6.5 Discussion of Current Pipeline Developments
- 6.6 Summary of Pipeline Drugs for ED, Phase I and Above
Chapter 7 The Counterfeit ED Drugs Market
- 7.1 Drug Counterfeiting: An Overview
- 7.2 The Different Types of Counterfeit Drugs
- 7.3 Viagra Counterfeits
- 7.4 Country Specific Patent Laws and How it can Influence Drug
Counterfeiting
- 7.5 The Growth of Internet Pharmacies Has Aided Viagra Sales
- 7.6 The Privacy Factor as a Driver of Online Sales
- 7.7 Online Viagra
- 7.8 Internet Erectile Dysfunctional Drugs Sales
- 7.9 Combating the Counterfeiters
Chapter 8 Conclusion
- 8.1 ED is a Serious Condition with High Prevalence
- 8.2 ED Market Analysis
- 8.3 Market Drivers
- 8.4 Market Restraints
- 8.5 New Products May Not Expand the Market Further
- 8.6 The Time to Erection is the Most Important Aspect of Any Novel ED Drug
- 8.7 The Key to Market Expansion is to Get More ED Men to Seek Medical
Advise
- 8.8 Strategies for Marketing: Changing Men' s Minds
- 8.9 Outlook for the Future of the ED Market
List of Tables
- Table 1.1 Top ED Drugs Revenue ($m), 2006
- Table 2.1 Major Drug Therapies for ED, 2006
- Table 2.2 Viagra, Cialis, and Levitra Revenues ($m) and Market Share (%),
2006
- Table 3.1 The Total World ED Drugs Market Forecast ($m), 2007-2012
- Table 3.2 Worldwide Revenues ($m) for ED Drugs, 2007-2012
- Table 3.3 The Worldwide Market Share by Revenue (%) for ED Drugs, 2007-2012
- Table 3.4 Viagra, Levitra and Cialis: Specific Product Advantages, 2007
- Table 3.5 Top 10 Leading Companies in the ED Market, Revenue ($m) and
Market Share (%), 2006
- Table 3.6 Market Share by Country Region by Revenue (%), 2006
- Table 4.1 A SWOT Chart for the ED Market
- Table 5.1 Types of Female Sexual Dysfunction and Prevalence
- Table 5.2 Drugs that Cause Decreased Sexual Desire
- Table 5.3 Drugs that Cause Decreased Sexual Arousal
- Table 6.1 Agents in Phase II of Clinical Development for ED, 2007
- Table 6.2 Summary of Pipeline Drugs for ED, Phase I and Above, 2007
List of Figures
- Figure 2.1 Worldwide Revenues ($m) for the ED Market, 2007-2012
- Figure 3.1 Total ED Drugs World Market Revenue Forecast ($m), 2007-2012
- Figure 3.2 Worldwide Revenues ($m) for ED Drugs, 2007-2012
- Figure 3.3 The Worldwide Market Share (%) By Revenue for Viagra, Levitra
and Cialis, 2007-2012
- Figure 3.4 Market Share (%) by Revenue of ED Drugs, 2006
- Figure 3.5 Market Share (%) by Revenue of ED Drugs, 2009
- Figure 3.6 Market Share (%) by Revenue of ED Drugs, 2012
- Figure 3.7 Leading Companies in the ED Market, Market Share (%), 2006
- Figure 3.8 Market Share by Country Region (%), 2006
- Figure 8.1 Total Sales of ED Drugs ($m), 2007-2012
- Figure 8.2 Sales of the Leading ED Drugs ($m), 2007-2012
List of Companies Mentioned
- Abbott
- Alza
- Bayer
- Dong-A
- Eczacibasi
- FDA
- Genentech
- GSK
- In2Gen
- Inotek
- Johnson & Johnson' s
- Kohl Medical
- Lilly
- MHRA
- Palatin
- Pfizer
- Schering-Plough
- SK Chemicals
- Spimaco
- Surface Logix
- Synvista
- Tanabe
- UCB
- Vectura
- Vivus
- WHO
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