Table of Contents
1. EXECUTIVE SUMMARY
- 1.1 Crucial Details of the Diabetes Market Trajectory
- 1.1.1 Visiongain Predicts the Diabetes Market will approach $64 billion
by 2023
- 1.1.2 Diabetes is Spreading at an Epidemic Rate: The Need for
Pharmaceuticals is Growing
- 1.1.3 Diabetes Care Works: The Market Will Expand Significantly
- 1.1.4 Awareness, Advocacy, and Government Spending aimed at Diabetes are
all Expanding
- 1.2 Aims, Scope and Format of the Report
- 1.3 Research Methodology
2. INTRODUCTION
- 2.1 What is Diabetes Mellitus?
- 2.1.1 Symptoms of Diabetes
- 2.1.2 Type 1 Diabetes
- 2.1.3 Type 2 Diabetes
- 2.1.4 Gestational Diabetes
- 2.1.5 Other types of Diabetes
- 2.1.6 “Pre-Diabetes”: Impaired Glucose Tolerance (IGT) and Metabolic
Syndrome
- 2.2 Health Consequences: Diabetes Can Cause Heart, Kidney, Eye, and Nerve
Damage
- 2.3 Obesity: The Major Diabetes Risk Factor
- 2.4 Other Risk Factors: Age, Genetics, Race
- 2.5 Diagnosis: Guidelines are Subject to Change
- 2.6 Prevalence: By All Measures, Diabetes Rates are Rising Epidemically
- 2.7 The Economic Costs of Diabetes: $58 billion in the US, $41 billion in
Africa
- 2.8 Treatments
- 2.8.1 Insulin: A Central Therapeutic Product
- 2.8.1.1 Crucial Insulin Characteristics: Onset, Peak, and Duration
Modifications
- 2.8.1.2 Invasive Insulin Delivery Methods: Injections, Pumps, Insulin
Jets
- 2.8.1.3 Moving Away from Injections? Alternative Delivery Methods
Under Development, and Set to Revolutionize the Market
- 2.8.2 Medications
- 2.8.3 More Novel Therapies? A New Discovery about How Insulin Works May
Lead to New Drugs
- 2.9 Diabetes Treatment Noncompliance Rates 25% to 90%
3. WORLD DIABETES MARKET, 2008-2023
- 3.1 Market Forecast, 2008-2023
- 3.2 Leading Drugs
- 3.2.1 Byetta: Potentially Revolutionary Blockbuster
- 3.2.2 Oral Antidiabetics Forecast
- 3.2.3 Actos
- 3.2.4 Avandia: Unlikely to Survive past 2013
- 3.2.5 Januvia
- 3.2.6 Avandamet
- 3.2.7 Human Insulin and Analogues Forecast
- 3.2.8 Lantus
- 3.2.9 Novorapid
- 3.2.10 Humalog
- 3.2.11 Novomix
- 3.2.12 Actraphane HM
- 3.2.13 Levemir
- 3.2.14 Other Diabetes-related Drugs: Symlin Up and Kinedak Down
- 3.3 Alternative Delivery Methods: The Possibilities to Watch
4. LEADING COMPANIES
- 4.1 Novo Nordisk
- 4.2 Takeda
- 4.3 Sanofi-aventis
- 4.4 Eli Lilly
- 4.5 Amylin
- 4.6 Pipeline Developments
- 4.6.1 Liraglutide
- 4.6.2 Other GLP-1 Analogues
- 4.6.3 DPP-4 Inhibitors
- 4.6.4 Biguanides
- 4.6.5 New Therapy Class: Sodium-glucose cotransporter-2 (SGLT2)
inhibitors
- 4.6.6 Insulin Pipelines: Some New Insulins, but Mostly Focused On
Delivery Methods
- 4.6.7 Pipeline for a Cure?
5. WORLD MARKET ANALYSIS BY REGION
- 5.1 United States
- 5.2 Europe
- 5.3 Japan
- 5.4 India: Becoming the Largest World Market?
- 5.5 China: Another Region to Watch Closely
- 5.6 The Rest of the World
6. SWOT (STRENGTHS, WEAKNESSES, OPPORTUNITIES, THREATS) ANALYSIS
- 6.1 Strengths: Diabetes is Increasing, and Diabetes Drugs Work
- 6.2 Weaknesses
- 6.3 Opportunities
- 6.4 Threats
- 6.4.1 The Most Significant Threat: Potential Changes in Drug Approval
Guidelines
- 6.4.2 Other Significant Threats
- 6.5 Interview with Fred Levine, M.D., Ph.D. Professor, Burnham Institute
for Medical Research; Director, Sanford Children' s Health Research Center
- 6.5.1 On alternative delivery methods:
- 6.5.2 On cardiovascular problems associated with oral antidiabetics
- 6.5.3 On obesity and diabetes
- 6.5.4 On Byetta
- 6.5.5 On Stem Cell Therapy/Cure
- 6.6 Interview with Bjorn Tyrberg, PhD. Associate Professor at Burnham
Institute for Medical Research, Diabetes and Obesity Research Center.
- 6.6.1 On Diet and Diabetes
- 6.6.2 On Byetta and liraglutide
7. CONCLUSIONS: DIABETES IS A GROWTH MARKET
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