Neurostimulation - Advanced Technologies and Global Market (2009 - 2014)

Table of Contents

1. INTRODUCTION

• 1.1. KEY TAKE-AWAYS
• 1.2. REPORT DESCRIPTION
• 1.3. MARKETS COVERED
• 1.4. STAKEHOLDERS

2. THE NERVOUS SYSTEM

• 2.1. TYPES OF NERVOUS SYSTEM DISORDERS
• 2.2. BRAIN DISORDERS
  • 2.2.1. Seizures/epilepsy
  • 2.2.2. Alzheimer' s Disease
• 2.3. SACRAL NERVE DISORDERS
• 2.4. NEUROSTIMULATION TREATMENTS FOR NEURO-DISORDERS

3. MARKET OVERVIEW OF GLOBAL NEUROSTIMULATION MARKET

• 3.1. DEFINING THE NEUROSTIMULATION PRODUCT MARKET
• 3.2. VALUE CHAIN ANALYSIS FOR NEUROSTIMULATION MARKET
  • 3.2.1. DEMAND-SIDE DRIVERS
    • 3.2.1.1. Longer lasting effect and shorter hospital stays
    • 3.2.1.2. Minimally-invasive technology
    • 3.2.1.3. Caters to the needs of the aging population
  • 3.2.2. SUPPLY-SIDE DRIVERS
    • 3.2.2.1. New market entrants and technology developments
    • 3.2.2.2. Extensive marketing dynamics
  • 3.2.3. RESTRAINTS
    • 3.2.3.1. High cost of treatment and lack of surgical skill
    • 3.2.3.2. Post-treatment side-effects and prolonged regulatory approvals
  • 3.2.4. OPPORTUNITIES
    • 3.2.4.1. Increasing awareness of neurostimulation in developing countries
    • 3.2.4.2. Gaps in the demand and supply cycle
  • 3.2.5. KEY COMPETITIVE POINTS
    • 3.2.5.1. Improved outcomes at competitive prices
    • 3.2.5.2. Better brand advertising for treatments and products
• 3.3. PRODUCT LIFECYCLE & MARKET DYNAMICS
  • 3.3.1. Promotional strategies
  • 3.3.2. Channel distribution strategies
• 3.4. DEFINING THE NEUROSTIMULATION APPLICATIONS MARKET
  • 3.5. NEUROSTIMULATION TECHNOLOGY MARKET
  • 3.5.1. SPINALCORD STIMULATOR DRIVING THE NEUROSTIMULATION PRODUCT MARKET
  • 3.5.2. ALZHEIMER' S AND PARKINSON' S DRIVING THE NEUROSTIMULATION APPLICATIONS MARKET

4. GLOBAL NEUROSTIMULATION PRODUCT MARKET

• 4.1. DRIVERS
  • 4.1.1. PORTABILITY, USER-FRIENDLINESS, & WIDE-RANGING APPLICATIONS
  • 4.1.2. INCREASING INTEREST OF VENTURE CAPITAL FIRMS
  • 4.1.3. EXTENSIVE PROMOTIONAL STRATEGIES OF MAJOR MARKET PLAYERS
• 4.2. SPINAL CORD STIMULATOR
  • 4.2.1. DRIVERS
    • 4.2.1.1. High efficiency in the treatment of chronic pain
    • 4.2.1.2. Cost benefits of spinal cord stimulation
  • 4.2.2. BONE GROWTH STIMULATOR
  • 4.2.3. SPINAL CORD FUSION STIMULATOR
• 4.3. DEEP BRAIN STIMULATOR
  • 4.3.1. DRIVERS
    • 4.3.1.1. Risk-less & flexible alternative to surgery
• 4.4. VAGUS NERVE STIMULATOR
• 4.5. SACRAL NERVOUS STIMULATOR
  • 4.5.1. DRIVERS
    • 4.5.1.1. Increase in incidence of urinal and incontinence disorders
    • 4.5.1.2. Shortening of surgical time increases revenues for stakeholders
• 4.6. GASTRIC ELECTRICAL STIMULATOR
  • 4.6.1. DRIVERS & RESTRAINTS
    • 4.6.1.1. Advantages over conventional treatment
    • 4.6.1.2. Gastric stimulation requires special surgical expertise

5. NEUROSTIMULATION APPLICATION MARKET

• 5.1. DRIVERS & RESTRAINTS
  • 5.1.1. ADVANTAGES OVER CONVENTIONAL SURGERY
  • 5.1.2. INCREASE IN AGING POPULATION
  • 5.1.3. COST FACTOR & INSUFFICIENT EXPERTISE
• 5.2. ALZHEIMER' S DISEASE
  • 5.2.1. DRIVERS
    • 5.2.1.1. Memory improvement & fewer side-effects
    • 5.2.1.2. Absence of an alternate cure for Alzheimer' s
• 5.3. PARKINSON' S DISEASE
• 5.4. PAIN
  • 5.4.1. ACUTE PAIN
  • 5.4.2. CHRONIC PAIN
    • 5.4.2.1. Drivers
    • 5.4.2.2. Migraine
    • 5.4.2.3. Other chronic pain
• 5.5. CHRONIC HEART FAILURE (CHF)
  • 5.5.1. DRIVERS
• 5.6. STROKE
  • 5.6.1. EPILEPSY
  • 5.6.2. DEPRESSION
    • 5.6.2.1. Drivers & Restraints
  • 5.6.3. OTHERS STROKES
• 5.7. PARALYSIS
• 5.8. OBESITY
  • 5.8.1. DRIVERS
    • 5.8.1.1. Increased accuracy in treating morbid obesity
    • 5.8.1.2. Reduced cost of hospital stays
• 5.9. ESSENTIAL TREMORS
• 5.10. EYE DISORDERS
  • 5.10.1. SECOND SIGHT DISORDERS
  • 5.10.2. OTHER EYE DISORDERS
• 5.11. OTHER NEUROSTIMULATION APPLICATIONS
• 5.12. GASTROPARESIS
• 5.13. INCONTINENCE

6. GLOBAL NEUROSTIMULATION TECHNOLOGY MARKET

• 6.1. DRIVERS
• 6.2. MINIMALLY-INVASIVE STIMULATION
  • 6.2.1. MAGNETIC NERVE STIMULATION
    • 6.2.1.1. Drivers
      • 6.2.1.1.1. Better treatment than anti-depression drugs
      • 6.2.1.1.2. Technology developments supporting market growth
  • 6.2.2. TRANSCUTANEOUS ELECTRICAL NEUROSTIMULATION
  • 6.2.3. OTHERS MINIMALLY-INVASIVE NEUROSTIMULATION TECHNOLOGY

7. GEOGRAPHIC ANALYSIS

• 7.1. NORTH AMERICA
• 7.2. EUROPE
• 7.3. ASIA
• 7.4. ROW

8. COMPETITIVE LANDSCAPE

9. NEUROSTIMULATION PATENT ANALYSIS

10. NEUROSTIMULATION COMPANY PROFILES

• 10.1. CYBERONICS, INC.
• 10.2. DYNATRONICS
• 10.3. ELEKTA AB
• 10.4. ENTEROMEDICS, INC.
• 10.5. GI DYNAMICS
• 10.6. H. LUNDBECK
• 10.7. IMPULSE DYNAMICS
• 10.8. INNOVATIVE NEUROTRONICS, INC.
• 10.9. INTEGRA LIFE SCIENCES HOLDINGS CORPORATION
• 10.10. MEDTRONIC, INC
• 10.11. NDI MEDICAL
• 10.12. NEURONETICS, INC.
• 10.13. NEUROPACE
• 10.14. NEUROTECH
• 10.15. NEXSTIM
• 10.16. RS MEDICAL
• 10.17. ST. JUDE MEDICAL, INC.
• 10.18. SYNAPSE BIOMEDICAL
• 10.19. THE MAGSTIM COMPANY LIMITED
• 10.20. VERTIS NEUROSCIENCE

APPENDIX

LIST OF TABLES

• TABLE 1 GLOBAL NEUROSTIMULATION MARKET, BY PRODUCT 2007 - 2014 ($MILLIONS)
• TABLE 2 GLOBAL NEUROSTIMULATION PRODUCT MARKET, BY GEOGRAPHY 2007 - 2014($ MILLIONS)
• TABLE 3 GLOBAL SPINAL CORD STIMULATOR MARKET, BY PRODUCT 2009 - 2014 ($ MILLIONS)
• TABLE 4 GLOBAL SPINAL CORD STIMULATOR MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 5 GLOBAL BONE GROWTH STIMULATOR MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 6 GLOBAL SPINAL CORD FUSION STIMULATOR MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 7 GLOBAL DEEP BRAIN STIMULATOR MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 8 GLOBAL VAGUS NERVE STIMULATOR MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 9 GLOBAL SACRAL NERVE STIMULATOR MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 10 GLOBAL GASTRIC ELECTRICAL STIMULATOR MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 11 GLOBAL NEUROSTIMULATION APPLICATIONS MARKET 2007 - 2014 ($ MILLIONS)
• TABLE 12 GLOBAL NEUROSTIMULATION APPLICATIONS MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 13 GLOBAL ALZHEIMER' S NEUROSTIMULATION MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 14 GLOBAL PARKINSON' S NEUROSTIMULATION MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 15 GLOBAL NEUROSTIMULATION PAIN APPLICATIONS MARKET 2007 - 2014 ($ MILLIONS)
• TABLE 16 GLOBAL PAIN NEUROSTIMULATION MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 17 GLOBAL ACUTE PAIN NEUROSTIMULATION MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 18 GLOBAL CHRONIC PAIN NEUROSTIMULATION MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 19 GLOBAL CHRONIC PAIN NEUROSTIMULATION MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 20 GLOBAL MIGRAINE NEUROSTIMULATION MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 21 GLOBAL OTHER CHRONIC PAIN NEUROSTIMULATION MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 22 GLOBAL CHRONIC HEART FAILURE NEUROSTIMULATION MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 23 GLOBAL NEUROSTIMULATION APPLICATIONS MARKET FOR STROKE, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 24 GLOBAL NEUROSTIMULATION APPLICATIONS MARKET FOR STROKE, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 25 GLOBAL NEUROSTIMULATION MARKET FOR EPILEPSY, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 26 GLOBAL NEUROSTIMULATION MARKET FOR DEPRESSION, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 27 GLOBAL NEUROSTIMULATION MARKET FOR OTHER STROKES, BY GEOGRAPHY 2007 - 2014($ MILLIONS
• TABLE 28 GLOBAL NEUROSTIMULATION MARKET FOR PARALYSIS, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 29 GLOBAL NEUROSTIMULATION MARKET FOR OBESITY, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 30 GLOBAL NEUROSTIMULATION MARKET FOR ESSENTIAL TREMORS, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 31 GLOBAL NEUROSTIMULATION APPLICATIONS MARKET FOR EYE DISEASES 2007 - 2014 ($ MILLIONS)
• TABLE 32 GLOBAL NEUROSTIMULATION MARKET FOR EYE DISEASES, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 33 GLOBAL NEUROSTIMULATION MARKET FOR SECOND SIGHT, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 34 GLOBAL NEUROSTIMULATION MARKET FOR OTHER EYE DISORDERS, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 35 GLOBAL OTHER NEUROSTIMULATION APPLICATIONS MARKET 2007 - 2014($ MILLIONS)
• TABLE 36 GLOBAL OTHER NEUROSTIMULATION APPLICATIONS MARKET, BY GEOGRAPHY 2007 - 2014($ MILLIONS)
• TABLE 37 GLOBAL NEUROSTIMULATION MARKET FOR GASTROPARESIS, BY GEOGRAPHY 2007 - 2014($ MILLIONS)
• TABLE 38 GLOBAL NEUROSTIMULATION MARKET FOR INCONTINENCE, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 39 GLOBAL NEUROSTIMULATION TECHNOLOGY MARKET, BY PRODUCT 2007 - 2014 ($ MILLIONS)
• TABLE 40 GLOBAL NEUROSTIMULATION TECHNOLOGY MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 41 GLOBAL MINIMALLY-INVASIVE NEUROSTIMULATION TECHNOLOGY MARKET, BY PRODUCT 2007 - 2014 ($ MILLIONS)
• TABLE 42 GLOBAL MINIMALLY-INVASIVE NEUROSTIMULATION TECHNOLOGY MARKET, BY GEOGRAPHY 2007 - 2014($ MILLIONS)
• TABLE 43 GLOBAL MINIMALLY-INVASIVE MAGNETIC NERVE NEUROSTIMULATION TECHNOLOGY MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 44 GLOBAL MINIMALLY-INVASIVE TRANSCUTANEOUS ELECTRICAL NEUROSTIMULATION TECHNOLOGY MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 45 GLOBAL OTHER MINIMALLY-INVASIVE NEUROSTIMULATION MARKET, BY GEOGRAPHY 2007 - 2014 ($ MILLIONS)
• TABLE 46 REGULATORY APPROVALS IN THE NEUROSTIMULATION MARKET (2008-2009)
• TABLE 47 NEW PRODUCT DEVELOPMENTS IN THE NEUROSTIMULATION MARKET (2008-2009)
• TABLE 48 NEUROSTIMULATION PATENTS FILED FROM 2004 TO JUNE 2009

LIST OF FIGURES

• FIGURE 1 NEUROSTIMULATION PRODUCT MARKET BY TOTAL MARKET SIZE (2007 - 2014)
• FIGURE 2 VALUE CHAIN ANALYSIS FOR NEUROSTIMULATION MARKET
• FIGURE 3 PRODUCT LIFE CYCLE GRAPH OF NEUROSTIMULATION MARKET
• FIGURE 4 NEUROSTIMULATION APPLICATIONS MARKET
• FIGURE 5 NEUROSTIMULATION PRODUCT MARKET SHARE AND MARKET GROWTH MATRIX ANALYSIS
• FIGURE 6 NEUROSTIMULATION APPLICATION MARKET SHARE AND MARKET GROWTH RATE MATRIX ANALYSIS 2009
• FIGURE 7 GEOGARPHICAL MARKET ANALYSIS OF THE PRODUCT MARKET (2009)
• FIGURE 8 REGULATORY APPROVALS IN THE NEUROSTIMULATION MARKET (2008-2009)
• FIGURE 9 NEW PRODUCT LAUNCHES IN THE NEUROSTIMULATION MARKET (2008-2009)
• FIGURE 10 NEUROSTIMULATION PATENTS FILED WORLDWIDE (2004 TO JUNE 2009)
• FIGURE 11 NEUROSTIMULATION PATENTS FILED WORLDWIDE FOR DIFFERENT CATEGORIES (2004 TO JUNE 2009)
• FIGURE 12 NEUROSTIMULATION PATENTS FILED IN NORTH AMERICA (2004 TO JUNE 2009)
• FIGURE 13 NEUROSTIMULATION PATENTS FILED IN EUROPE (2004 TO JUNE 2009)
• FIGURE 14 NEUROSTIMULATION PATENTS FILED IN ASIA (2004 TO JUNE 2009)