US Markets for Soft Tissue Repair 2009

Table of Contents

LIST OF EXHIBITS

EXECUTIVE SUMMARY

METHODOLOGY

1.0 US SOFT TISSUE REPAIR DEVICE MARKET

• 1.1 Market Overview
• 1.2 Market Analysis
• 1.2.1 Procedures
• 1.2.2 Market Forecast
• 1.2.3 Market Drivers and Limiters
• 1.2.3.1 Market Drivers
• 1.2.3.2 Market Limiters
• 1.3 Competitive Analysis

2.0 VENTRAL HERNIA REPAIR DEVICE MARKET

• 2.1 Market Overview
• 2.2 Market Analysis
• 2.2.1 Procedures
• 2.2.1.1 Tension-Free Ventral Hernia Repairs
• Laparoscopic and Open Ventral Hernia Repairs
• 2.2.2 Market Forecast
• 2.2.2.1 Synthetic Mesh Market
• 2.2.2.2 Biologic Mesh Market
• 2.2.3 Market Drivers and Limiters
• 2.3 Competitive Analysis

3.0 PELVIC FLOOR RECONSTRUCTION DEVICE MARKET

• 3.1 Market Overview
• 3.2 Market Analysis
• 3.2.1 Market Definitions
• 3.2.2 Procedures
• 3.2.3 Market Forecast
• 3.2.3.1 Synthetic Pelvic Floor Reconstruction Device Market
• 3.2.3.2 Biologic Pelvic Floor Reconstruction Device Market
• Xenograft Pelvic Floor Reconstruction Device Market
• Allograft Pelvic Floor Reconstruction Device Market
• 3.2.4 Market Drivers and Limiters
• 3.3 Competitive Analysis

4.0 VAGINAL SLING MARKET

• 4.1 Market Overview
• 4.2 Market Analysis
• 4.2.1 Procedures
• 4.2.2 Market Forecast
• 4.2.2.1 Fixationless Vaginal Sling Market
• Transobturator Fixationless Vaginal Sling Market
• Other Fixationless Vaginal Sling Market
• 4.2.2.2 Traditional Vaginal Sling Market
• 4.2.3 Market Drivers and Limiters
• 4.3 Competitive Analysis

5.0 INGUINAL HERNIA REPAIR DEVICE MARKET

• 5.1 Market Overview
• 5.2 Market Analysis
• 5.2.1 Procedures
• 5.2.1.1 Tension-Free Inguinal Hernia Repairs
• Laparoscopic and Open Inguinal Hernia Repairs
• 5.2.2 Market Forecast
• 5.2.2.1 Synthetic Mesh Market
• 5.2.2.2 Biologic Mesh Market
• 5.2.3 Market Drivers and Limiters
• 5.3 Competitive Analysis

6.0 DURAL REPAIR DEVICE MARKET

• 6.1 Market Overview
• 6.2 Market Analysis
• 6.2.1 Procedures
• 6.2.2 Market Forecast
• 6.2.2.1 Biologic Mesh Market
• Collagen Sponge Market
• Suturable Xenograft Market
• Allograft Market
• 6.2.2.2 Synthetic Market
• 6.2.3 Market Drivers and Limiters
• 6.3 Competitive Analysis

7.0 ROTATOR CUFF REINFORCEMENT GRAFT MARKET

• 7.1 Market Overview
• 7.2 Market Analysis
• 7.2.1 Procedures
• 7.2.2 Market Forecast
• 7.2.2.1 Biologic Market
• Xenograft Market
• Allograft Market
• 7.2.2.2 Synthetic Graft Market
• 7.2.3 Market Drivers and Limiters
• 7.3 Competitive Analysis

8.0 STAPLE LINE REINFORCEMENT DEVICE MARKET

• 8.1 Market Overview
• 8.2 Market Analysis
• 8.2.1 Market Definition
• 8.2.2 Procedures
• 8.2.2.1 Bariatric Staple Line Reinforcement Procedures
• 8.2.2.2 Thoracic Staple Line Reinforcement Procedures
• 8.2.2.3 Other Staple Line Reinforcement Procedures
• 8.2.3 Market Forecast
• 8.2.3.1 Biologic Mesh Market
• 8.2.3.2 Synthetic Mesh Market
• 8.2.4 Market Drivers and Limiters
• 8.3 Competitive Analysis

APPENDIX A: MRG ACRONYMS AND INITIALISMS

APPENDIX B: SUPPLEMENTAL EXHIBITS

List of Exhibits

EXECUTIVE SUMMARY X

• Exhibit 1: Soft Tissue Repair Device Market, by Segment, US (US$), 2007 - 2013 X
• Exhibit 2: Ventral Hernia Repair Device Market, by Material, US (US$), 2007 - 2013 XI
• Exhibit 3: PFR Device Market, by Type, US (US$), 2007 - 2013 XII
• Exhibit 4: Vaginal Sling Market, by Type, US (US$), 2007 - 2013 XIII
• Exhibit 5: Inguinal Hernia Repair Device Market, by Material, US (US$), 2007 - 2013 XIV
• Exhibit 6: Dural Repair Device Market, by Surgery Type, US (US$), 2007 - 2013 XV
• Exhibit 7: Rotator Cuff Reinforcement Graft Market, by Material, US (US$), 2007 - 2013 XVI
• Exhibit 8: SLR Device Market, by Material, US (US$), 2007 - 2013 XVII
• Exhibit 9: Leading Competitors in the Soft Tissue Repair Device Market, US, 2008 XVIII

CHAPTER 1: US SOFT TISSUE REPAIR DEVICE MARKET 1

• Exhibit 10: Soft Tissue Repair Device Market, US (US$), 2007 - 2013 1
• Exhibit 11: Soft Tissue Repair Device Market, by Segment, US (US$), 2007 - 20133
• Exhibit 12: Drivers of the Soft Tissue Repair Device Market, US 4
• Exhibit 13: Leading Competitors in the Soft Tissue Repair Device Market, by Segment, as a % of Total, US, 2008 7

CHAPTER 2: VENTRAL HERNIA REPAIR DEVICE MARKET 15

• Exhibit 14: Ventral Hernia Repair Device Market, US (US$), 2007 - 2013 15
• Exhibit 15: Ventral Hernia Repairs, by Type, US, 2007 - 2013 19
• Exhibit 16: Ventral Hernia Tension-Free Repairs, by Type, US, 2007 - 2013 20
• Exhibit 17: Ventral Hernia Repair Device Market, by Material, US (US$), 2007 - 2013 22
• Exhibit 18: Synthetic Mesh Market, by Type, US (US$), 2007 - 2013 24
• Exhibit 19: Nonadhesive Mesh Market, US (US$), 2007 - 2013 25
• Exhibit 20: Flatsheet Mesh Market, US (US$), 2007 - 2013 26
• Exhibit 21: Biologic Mesh Market, by Type, US (US$), 2007 - 2013 29
• Exhibit 22: Allograft Mesh Market, US (US$), 2007 - 2013 30
• Exhibit 23: Xenograft Mesh Market, US (US$), 2007 - 2013 31
• Exhibit 24: Drivers of the Ventral Hernia Repair Device Market, US 32
• Exhibit 25: Limiters of the Ventral Hernia Repair Device Market, US 33
• Exhibit 26: Leading Competitors in the Ventral Hernia Repair Device Market, by Material, as a % of Total, US, 2008 34

CHAPTER 3: PELVIC FLOOR RECONSTRUCTION DEVICE MARKET 35

• Exhibit 27: PFR Device Market, US (US$), 2007 - 2013 35
• Exhibit 28: PFR Products, by Type, US, 2008 37
• Exhibit 29: Major Types of POP 39
• Exhibit 30: Surgical PFR Procedures, US, 2007 - 2013 40
• Exhibit 31: Hysterectomies for the Treatment of Uterine Prolapse, US, 2007 - 201340
• Exhibit 32: PFR Device Market, by Type, US (US$), 2007 - 2013 41
• Exhibit 33: PFR Device Market, by Material, US (US$), 2007 - 2013 42
• Exhibit 34: Synthetic PFR Device Market, by Type, US (US$), 2007 - 2013 44
• Exhibit 35: Synthetic PFR Device Market Growth, by Type, US, 2008 - 2013 45
• Exhibit 36: Xenograft PFR Device Market, by Type, US (US$), 2007 - 2013 47
• Exhibit 37: Xenograft PFR Device Market Growth, by Type, US, 2008 - 2013 48
• Exhibit 38: Allograft PFR Device Market, by Type, US (US$), 2007 - 2013 49
• Exhibit 39: Allograft PFR Device Market Growth, by Type, US, 2008 - 2013 50
• Exhibit 40: Drivers of the PFR Device Market, US 51
• Exhibit 41: Limiters of the PFR Device Market, US 52
• Exhibit 42: Leading Competitors in the PFR Device Market, as a % of Total, US, 2008 53

CHAPTER 5: VAGINAL SLING MARKET 54

• Exhibit 43: Vaginal Sling Market, by Type, US (US$), 2007 - 2013 54
• Exhibit 44: Vaginal Sling Procedures, by Type, US, 2007 - 2013 56
• Exhibit 45: Commercial Vaginal Sling Procedures, by Type, US, 2007 - 2013 57
• Exhibit 46: Selected Advantages and Disadvantages of Vaginal Slings, by Material 58
• Exhibit 47: Vaginal Sling Market, by Type, US (US$), 2007 - 2013 59
• Exhibit 48: Fixationless Vaginal Sling Market, by Type, US (US$), 2007 - 201360
• Exhibit 49: Transobturator Fixationless Vaginal Sling Market, US (US$), 2007 - 2013 61
• Exhibit 50: Other Fixationless Vaginal Sling Market, US (US$), 2007 - 2013 62
• Exhibit 51: Traditional Vaginal Sling Market, US (US$), 2007 - 2013 63
• Exhibit 52: Drivers of the Vaginal Sling Market, US 64
• Exhibit 53: Limiters of the Vaginal Sling Market, US65
• Exhibit 54: Leading Competitors in the Vaginal Sling Market, by Type, as a % of Total, US, 2008 66

CHAPTER 6: INGUINAL HERNIA REPAIR DEVICE MARKET 67

• Exhibit 55: Inguinal Hernia Repair Device Market, US (US$), 2007 - 2013 67
• Exhibit 56: Inguinal Hernia Repairs, by Type, US, 2007 - 2013 71
• Exhibit 57: Inguinal Hernia Tension-Free Repairs, by Type, US, 2007 - 2013 72
• Exhibit 58: Inguinal Hernia Repair Device Market, by Material, US (US$), 2007 - 2013 74
• Exhibit 59: Synthetic Mesh Market, by Type, US (US$), 2007 - 2013 76
• Exhibit 60: Proprietary Mesh Market, US (US$), 2007 - 2013 77
• Exhibit 61: Flatsheet Mesh Market, US (US$), 2007 - 2013 78
• Exhibit 62: Biologic Mesh Market, by Type, US (US$), 2007 - 2013 80
• Exhibit 63: Allograft Mesh Market, US (US$), 2007 - 2013 81
• Exhibit 64: Xenograft Mesh Market, US (US$), 2007 - 2013 82
• Exhibit 65: Drivers of the Inguinal Hernia Repair Device Market, US 83
• Exhibit 66: Limiters of the Inguinal Hernia Repair Device Market, US 84
• Exhibit 67: Leading Competitors in the Inguinal Hernia Repair Device Market, by Material, as a % of Total, US, 2008 85

CHAPTER 7: DURAL REPAIR DEVICE MARKET 86

• Exhibit 68: Dural Repair Device Market, US (US$), 2007 - 2013 86
• Exhibit 69: Commercial Mesh Dural Repairs, by Indication, US, 2007 - 2013 89
• Exhibit 70: Dural Repair Device Market, by Indication, US (US$), 2007 - 2013 91
• Exhibit 71: Dural Repair Device Market, by Material, US (US$), 2007 - 2013 92
• Exhibit 72: Dural Repair Device Market, by Use, US (US$), 2007 - 2013 93
• Exhibit 73: Collagen Sponge Market, by Surgery Type, US (US$), 2007 - 2013 95
• Exhibit 74: Cranial Collagen Sponge Market, by Use, US (US$), 2007 - 2013 96
• Exhibit 75: Cranial Collagen Sponge Market Growth, by Use, US, 2008 - 2013 97
• Exhibit 76: Spinal Collagen Sponge Market, by Use, US (US$), 2007 - 2013 98
• Exhibit 77: Spinal Collagen Sponge Market Growth, by Use, US (US$), 2008 - 2013 99
• Exhibit 78: Suturable Xenograft Market, by Surgery Type, US (US$), 2007 - 2013 100
• Exhibit 79: Cranial Suturable Xenograft Market, US (US$), 2007 - 2013101
• Exhibit 80: Spinal Suturable Xenograft Market, US (US$), 2007 - 2013102
• Exhibit 81: Allograft Market, by Surgery Type, US (US$), 2007 - 2013103
• Exhibit 82: Cranial Allograft Market, US (US$), 2007 - 2013 104
• Exhibit 83: Spinal Allograft Market, US (US$), 2007 - 2013 105
• Exhibit 84: Synthetic Market, by Surgery Type, US (US$), 2007 - 2013106
• Exhibit 85: Cranial Synthetic Market, US (US$), 2007 - 2013 107
• Exhibit 86: Spinal Synthetic Market, US (US$), 2007 - 2013 108
• Exhibit 87: Drivers of the Dural Repair Device Market, US 109
• Exhibit 88: Limiters of the Dural Repair Device Market, US 110
• Exhibit 89: Leading Competitors in the Dural Repair Device Market, as a % of Total, US, 2008 111

CHAPTER 8: ROTATOR CUFF REINFORCEMENT GRAFT MARKET 112

• Exhibit 90: Rotator Cuff Reinforcement Graft Market, US (US$), 2007 - 2013 112
• Exhibit 91: Rotator Cuff Repairs, by Scope, US, 2007 - 2013114
• Exhibit 92: Major Repair Rotator Cuff Repairs, by Type, US, 2007 - 2013 115
• Exhibit 93: Rotator Cuff Reinforcement Graft Market, by Material, US (US$), 2007 - 2013 117
• Exhibit 94: Xenograft Market, by Type, US (US$), 2007 - 2013 120
• Exhibit 95: Xenograft Market Growth, by Type, US, 2008 - 2013121
• Exhibit 96: Xenograft Market, by Type, as a % of Total, US, 2007 - 2013 122
• Exhibit 97: Allograft Market, US (US$), 2007 - 2013 123
• Exhibit 98: Synthetic Graft Market, US (US$), 2007 - 2013 124
• Exhibit 99: Drivers of the Rotator Cuff Reinforcement Graft Market, US125
• Exhibit 100: Limiters of the Rotator Cuff Reinforcement Graft Market, US 126
• Exhibit 101: Leading Competitors in the Rotator Cuff Reinforcement Graft Market, by Material, as a % of Total, US, 2008 127
• Exhibit 102: Leading Competitors in the Rotator Cuff Reinforcement Xenograft Market, by Type, as a % of Total, US, 2008 127

CHAPTER 9: STAPLE LINE REINFORCEMENT DEVICE MARKET 128

• Exhibit 103: SLR Device Market, US (US$), 2007 - 2013 (Graphical Format) 128
• Exhibit 104: Bariatric Procedures, by Approach, US, 2007 - 2013 132
• Exhibit 105: SLR Procedures, by Type, US, 2007 - 2013 133
• Exhibit 106: SLR Device Market, by Material, US (US$), 2007 - 2013 (Tabular Format) 135
• Exhibit 107: Biologic Mesh Market, US (US$), 2007 - 2013 136
• Exhibit 108: Synthetic Mesh Market, US (US$), 2007 - 2013 137
• Exhibit 109: Drivers of the SLR Device Market, US 138
• Exhibit 110: Limiters of the SLR Device Market, US 139
• Exhibit 111: Leading Competitors in the SLR Device Market, as a % of Total, US, 2008 140

APPENDIX B: SUPPLEMENTAL EXHIBITS 142

• Exhibit 112: Soft Tissue Repair Device Market, by Segment, US (US$), 2007 - 2013142
• Exhibit 113: Ventral Hernia Repair Device Market, by Material, US (US$), 2007 - 2013 143
• Exhibit 114: PFR Device Market, by Type, US (US$), 2007 - 2013 143
• Exhibit 115: Vaginal Sling Market, by Type, US (US$), 2007 - 2013 144
• Exhibit 116: Inguinal Hernia Repair Device Market, by Material, US (US$), 2007 - 2013 144
• Exhibit 117: Dural Repair Device Market, by Indication, US (US$), 2007 - 2013145
• Exhibit 118: Rotator Cuff Reinforcement Graft Market, by Material, US (US$), 2007 - 2013 145
• Exhibit 119: SLR Device Market, by Material, US (US$), 2007 - 2013 146