US Markets for Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers 2009

Table of Contents

TABLE OF CONTENTS

LIST OF EXHIBITS

EXECUTIVE SUMMARY

METHODOLOGY

1.0 US SURGICAL HEMOSTAT, INTERNAL TISSUE SEALANT, AND ADHESION BARRIER MARKET

• 1.1 Market Overview
• 1.2 Market Definitions
• 1.3 Market Analysis
  • 1.3.1 Economic Assumptions for the Forecast Period
  • 1.3.2 Market Forecast
  • 1.3.3 Market Drivers and Limiters
    • 1.3.3.1 Market Drivers
    • 1.3.3.2 Market Limiters
• 1.4 Competitive Analysis
  • King Pharmaceuticals
  • ETHICON
  • Baxter BioSurgery
  • Genzyme Biosurgery
  • Pfizer
  • Other

2.0 SURGICAL HEMOSTAT MARKET

• 2.1 Market Overview
• 2.2 Product Overview
• 2.3 Market Analysis
  • 2.3.1 Thrombin�]Based Hemostat Market
  • 2.3.2 Oxidized Regenerated Cellulose�]Based Hemostat Market
  • 2.3.3 Gelatin�]Based Hemostat Market
  • 2.3.4 Combination Hemostat Market
  • 2.3.5 Collagen�]Based Hemostat Market
  • 2.3.6 Autologous�]Based Hemostat Market
  • 2.3.7 Polysaccharide�]Based Hemostat Market
  • 2.3.8 Market Drivers and Limiters
    • 2.3.8.1 Market Drivers
    • 2.3.8.2 Market Limiters
    • 2.3.8.3 Trends and Issues
• 2.4 Competitive Analysis
  • 2.4.1 Leading Competitors
    • King Pharmaceuticals
    • ETHICON
    • Baxter BioSurgery
    • Pfizer
    • Davol
    • Orthovita
    • ZymoGenetics
    • CryoLife
    • Integra LifeSciences
    • Medafor
  • 2.4.2 Emerging Competitors
    • Baxter BioSurgery' s Antibiotic Hemostat
    • ETHICON and OMRIX Biopharmaceuticals' Fibrin Patch

3.0 INTERNAL TISSUE SEALANT MARKET

• 3.1 Market Overview
• 3.2 Product Overview
• 3.3 Market Analysis
  • 3.3.1 Fibrin�]Based Internal Tissue Sealant Market
  • 3.3.2 Synthetic�]Based Internal Tissue Sealant Market
  • 3.3.3 Protein�]Based Internal Tissue Sealant Market
  • 3.3.4 Market Drivers and Limiters
    • 3.3.4.1 Market Drivers
    • 3.3.4.2 Market Limiters
    • 3.3.4.3 Trends and Issues
• 3.4 Competitive Analysis
  • 3.4.1 Leading Competitors
    • Baxter BioSurgery
    • ETHICON
    • CryoLife
    • Covidien
  • 3.4.2 Emerging Competitors
    • NeoMend' s ProGEL Series
    • Baxter BioSurgery and Nycomed' s TachoSil
    • Haemacure' s Hemaseel HMN
    • Covidien' s PleuraSeal and DuraSeal Xact
• 3.5 End�]User Survey Results

4.0 ADHESION BARRIER MARKET

• 4.1 Market Overview
• 4.2 Adhesion Formation Overview
• 4.3 Product Overview
  • 4.3.1 Films
  • 4.3.2 Hydroflotation
  • 4.3.3 Gels
  • 4.3.4 Soft Tissue Attachment Products
• 4.4 Market Analysis
  • 4.4.1 Market Drivers and Limiters
    • 4.4.1.1 Market Drivers
    • 4.4.1.2 Market Limiters
• 4.5 Competitive Analysis
  • 4.5.1 Leading Competitors
    • Genzyme Biosurgery
    • ETHICON
    • Baxter BioSurgery
    • MAST Biosurgery
    • CryoLife
  • 4.5.2 Emerging Competitors
    • OMRIX Biopharmaceuticals' Adhexil
    • Angiotech Pharmaceuticals' Adhibit
    • Integra LifeScience' s DuraGen Plus
    • Fidia Advanced Biopolymers and Nordic Pharma Group' s Hyalobarrier Gel
    • FzioMed' s Oxiplex/SP Gel
    • NeoMend' s ProGEL�]AB
    • SyntheMed' s REPEL�]CV Adhesion Barrier
    • Covidien' s SprayShield Adhesion Barrier System
    • Genzyme Biosurgery' s Sepraspray
• 4.6 End�]User Survey Results

APPENDIX A: MRG ACRONYMS AND INITIALISMS

APPENDIX B: SUPPLEMENTAL EXHIBITS

List of Exhibits

EXECUTIVE SUMMARY

• Exhibit 1: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier Market, by Segment, US (US$), 2007 - 2013
• Exhibit 2: Surgical Hemostat Market, by Segment, US (US$), 2007 - 2013
• Exhibit 3: Internal Tissue Sealant Market Growth, by Segment, US, 2008 - 2013
• Exhibit 4: Adhesion Barrier Market, US (US$), 2007 - 2013
• Exhibit 5: Leading Competitors in the Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier Market, US, 2008

CHAPTER 1: US SURGICAL HEMOSTAT, INTERNAL TISSUE SEALANT, AND ADHESION BARRIER MARKET

• Exhibit 6: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier Market, US (US$), 2007 - 2013
• Exhibit 7: Surgical Hemostat, Internal Tissue Sealants, and Adhesion Barrier Market Segments and Related Products, US, 2008
• Exhibit 8: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier Market, by Segment, US (US$), 2007 - 2013
• Exhibit 9: Drivers and Limiters of the Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier Market, US
• Exhibit 10: Leading Competitors in the Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier Market, as a % of Total, US, 2008
• Exhibit 11: Leading Competitors in the Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier Market, by Segment, as a % of Total, US, 2008

CHAPTER 2: SURGICAL HEMOSTAT MARKET

• Exhibit 12: Surgical Hemostat Market, US (US$), 2007 - 2013
• Exhibit 13: Coagulation Cascade
• Exhibit 14: Surgical Hemostat Product Overview, US, 2008
• Exhibit 15: Surgical Hemostat Product Overview, US, 2008, Continued
• Exhibit 16: Surgical Hemostat Market, by Segment, US (US$), 2007 - 2013
• Exhibit 17: Surgical Hemostat Market Growth, by Segment, US, 2008 - 2013
• Exhibit 18: Surgical Hemostat Market, by Segment, as a % of Total, US, 2007 - 2013
• Exhibit 19: Thrombin�]Based Surgical Hemostat Market, US (US$), 2007 - 2013
• Exhibit 20: ORC�]Based Surgical Hemostat Market, US (US$), 2007 - 2013
• Exhibit 21: Gelatin�]Based Surgical Hemostat Market, US (US$), 2007 - 2013
• Exhibit 22: Combination Surgical Hemostat Market, US (US$), 2007 - 2013
• Exhibit 23: Collagen�]Based Surgical Hemostat Market, US (US$), 2007 - 2013
• Exhibit 24: Autologous�]Based Surgical Hemostat Market, US (US$), 2007 - 2013
• Exhibit 25: Polysaccharide�]Based Surgical Hemostat Market, US (US$), 2007 - 2013
• Exhibit 26: Drivers and Limiters of the Surgical Hemostat Market, US
• Exhibit 27: Leading Competitors in the Surgical Hemostat Market, as a % of Total, US, 2008
• Exhibit 28: Leading Competitors in the Surgical Hemostat Market, by Segment, as a % of Total, US, 2008

CHAPTER 3: INTERNAL TISSUE SEALANT MARKET

• Exhibit 29: Internal Tissue Sealant Market, by Segment, US (US$), 2007 - 2013
• Exhibit 30: Internal Tissue Sealant Product Overview, US, 2008
• Exhibit 31: Internal Tissue Sealant Market, by Segment, US (US$), 2007 - 2013
• Exhibit 32: Fibrin�]Based Internal Tissue Sealant Market, US (US$), 2007 - 2013
• Exhibit 33: Synthetic�]Based Internal Tissue Sealant Market, US (US$), 2007 - 2013
• Exhibit 34: Protein�]Based Internal Tissue Sealant Market, US (US$), 2007 - 2013
• Exhibit 35: Drivers and Limiters of the Internal Tissue Sealant Market, US
• Exhibit 36: Leading Competitors in the Internal Tissue Sealant Market, as a % of Total, US, 2008
• Exhibit 37: Leading Competitors in the Internal Tissue Sealant Market, by Segment, as a % of Total, US, 2008
• Exhibit 38: Orthopedic Surgeons' Internal Tissue Sealant Usage, 2008
• Exhibit 39: Orthopedic Surgeons' Internal Tissue Sealant Usage, by Procedure Type, 2008
• Exhibit 40: Importance of Internal Tissue Sealant FDA Approval for Orthopedic Surgeons, 2008

CHAPTER 4: ADHESION BARRIER MARKET

• Exhibit 41: Adhesion Barrier Market, US (US$), 2007 - 2013
• Exhibit 42: Adhesion Barrier Products, US, 2008
• Exhibit 43: Select STA Products, US, 2008
• Exhibit 44: Adhesion Barrier Market, US (US$), 2007 - 2013
• Exhibit 45: Drivers and Limiters of the Adhesion Barrier Market, US, 2008
• Exhibit 46: Select List of Adhesion Barrier Clinical Trials, US, 2008
• Exhibit 47: Leading Competitors in the Adhesion Barrier Market, as a % of Total, US, 2008 (Graphical Format)
• Exhibit 48: Leading Competitors in the Adhesion Barrier Market, as a % of Total, US, 2008 (Tabular Format)
• Exhibit 49: Orthopedic Surgeon Adhesion Barrier Usage, 2008
• Exhibit 50: Orthopedic Surgeon Adhesion Barrier Usage, by Procedure Type, 2008
• Exhibit 51: Orthopedic Surgeon Adhesion Barrier Usage, by Brand, 2008
• Exhibit 52: Factors Influencing Orthopedic Surgeon Adhesion Barrier Product Choice, 2008
• Exhibit 53: Orthopedic Surgeon Adhesion Barrier Usage, as a % of Total Orthopedic Procedures, 2008
• Exhibit 54: Adhesion Complications, as a % of Total, 2008
• Exhibit 55: Importance of Adhesion Barrier FDA Approval for Orthopedic Surgeons, 2008

APPENDIX B: SUPPLEMENTAL EXHIBITS

• Exhibit 56: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier Market, by Segment, US (US$), 2007 - 2013 (Detailed Format)
• Exhibit 57: Surgical Hemostat Market, by Segment, US (US$), 2007 - 2013 (Detailed Format)
• Exhibit 58: Internal Tissue Sealant Market Growth, by Segment, US, 2008 - 2013 (Detailed Format)
• Exhibit 59: Adhesion Barrier Market, US (US$), 2007 - 2013 (Detailed Format)