US Markets for Clot Management Devices 2009

Table of Contents

TABLE OF CONTENTS

LIST OF EXHIBITS

EXECUTIVE SUMMARY

METHODOLOGY

1.0 US CLOT MANAGEMENT DEVICE MARKET

• 1.1 Market Overview
• 1.2 Disease Overview
• 1.2.1 Thrombosis
• 1.3 Indication Overview
  • 1.3.1 Arteriovenous Access Thrombosis
  • 1.3.2 Peripheral Artery Thrombosis
  • 1.3.3 Venous Thromboembolism
    • 1.3.3.1 Deep Vein Thrombosis
    • 1.3.3.2 Post - Thrombotic Syndrome
  • 1.3.4 Pulmonary Embolism
  • 1.3.5 Coronary Thrombosis
  • 1.3.6 Acute Ischemic Stroke
• 1.4 Market Analysis
  • 1.4.1 Economic Assumptions for the Forecast Period
  • 1.4.2 Procedures by Type
    • 1.4.2.1 Thrombectomies
      • Percutaneous Thrombectomies
      • Surgical Thrombectomies
    • 1.4.2.2 Inferior Vena Cava Filter Placements
    • 1.4.2.3 Catheter - Directed Thrombolysis Procedures
    • 1.4.2.4 Neurovascular Embolectomies
  • 1.4.3 Procedures by Indication
    • 1.4.3.1 Arteriovenous Clot Management Procedures
    • 1.4.3.2 Peripheral Artery Clot Management Procedures
    • 1.4.3.3 Venous Clot Management Procedures
    • 1.4.3.4 Pulmonary Embolism Clot Management Procedures
    • 1.4.3.5 Coronary Clot Management Procedures
    • 1.4.3.6 Neurovascular Clot Management Procedures
  • 1.4.4 Market Forecast
  • 1.4.5 Market Drivers and Limiters
• 1.5 Competitive Analysis
  • 1.5.1 Market Shares

2.0 THROMBECTOMY DEVICE MARKET

• 2.1 Market Overview
• 2.2 Market Analysis
  • 2.2.1 Procedures
    • 2.2.1.1 Percutaneous Thrombectomies
    • 2.2.1.2 Surgical Thrombectomies
  • 2.2.2 Procedures by Device Type
    • 2.2.2.1 Mechanical Thrombectomies
    • 2.2.2.2 Clot Aspiration Procedures
    • 2.2.2.3 Pharmacomechanical Thrombectomies
    • 2.2.2.4 Balloon Embolectomies
  • 2.2.3 Key Clinical Trial Summaries
  • 2.2.4 Market Forecast
    • 2.2.4.1 Mechanical Thrombectomy Catheter Market
    • 2.2.4.2 Aspiration Catheter Market
    • 2.2.4.3 Pharmacomechanical Thrombectomy Device Market
    • 2.2.4.4 Embolectomy Balloon Catheter Market
  • 2.2.5 Market Drivers and Limiters
• 2.3 Competitive Analysis
  • 2.3.1 Market Shares
  • 2.3.2 Competitor Discussions (in Alphabetical Order)
    • Arrow International (a Teleflex Medical Company)
    • Bacchus Vascular (acquired by Covidien)
    • EKOS
    • MEDRAD Interventional/Possis Medical
    • Medtronic
    • Spectranetics
    • Vascular Solutions
    • Other

3.0 INFERIOR VENA CAVA FILTER MARKET

• 3.1 Market Overview
• 3.2 Market Analysis
  • 3.2.1 Procedures
  • 3.2.2 Market Forecast
    • 3.2.2.1 Retrievable Inferior Vena Cava Filter Market
    • 3.2.2.2 Permanent Inferior Vena Cava Filter Market
  • 3.2.3 Market Drivers and Limiters
• 3.3 Competitive Analysis
  • 3.3.1 Market Shares
  • 3.3.2 Competitor Discussions (in Alphabetical Order)
    • ALN
    • B. Braun
    • Boston Scientific
    • Cook Medical
    • Cordis
    • C. R. Bard
    • 3.3.3 Emerging Competitors
    • Rafael Medical Technologies and MEDRAD Interventional/Possis Medical
    • Rex Medical/Angiotech

4.0 THROMBOLYTIC INFUSION CATHETER MARKET

• 4.1 Market Overview
• 4.2 Market Analysis
  • 4.2.1 Thrombolytic Agents
    • 4.2.1.1 Recombinant Tissue Plasminogen Activator
  • 4.2.2 Procedures
    • 4.2.2.1 Catheter - Directed Thrombolysis
  • 4.2.3 Procedures by Indication
    • 4.2.3.1 Arteriovenous Catheter - Directed Thrombolysis Procedures
    • 4.2.3.2 Peripheral Artery Catheter - Directed Thrombolysis Procedures
    • 4.2.3.3 Venous Catheter - Directed Thrombolysis Procedures
    • 4.2.3.4 Pulmonary Embolism Catheter - Directed Thrombolysis Procedures
    • 4.2.3.5 Coronary Catheter - Directed Thrombolysis Procedures
    • 4.2.3.6 Neurovascular Catheter - Directed Thrombolysis Procedures
      • Intravenous Thrombolysis in Acute Ischemic Stroke
      • Intra - arterial Thrombolysis in Acute Ischemic Stroke
      • Combination Thrombolysis in Stroke: Intravenous/Intra - Arterial
      • Recombinant Tissue Plasminogen Activator
  • 4.2.4 Key Clinical Trial Summaries
  • 4.2.5 Market Forecast
  • 4.2.6 Market Drivers and Limiters
• 4.3 Competitive Analysis
  • 4.3.1 Market Shares
  • 4.3.2 Competitor Discussions (in Alphabetical Order)
    • AngioDynamics
    • Cook Medical
    • EKOS
    • ev3
    • Merit Medical Systems
    • Other

5.0 NEUROVASCULAR EMBOLECTOMY DEVICE MARKET

• 5.1 Market Overview
• 5.2 Market Analysis
  • 5.2.1 Stroke Overview
  • 5.2.2 Treatment of Acute Ischemic Stroke
    • 5.2.2.1 Medical Stroke Treatment
    • 5.2.2.2 Endovascular Stroke Treatment
  • 5.2.3 Key Clinical Trial Summaries
    • 5.2.3.1 Stroke Assessment Scales
  • 5.2.4 Procedures
  • 5.2.5 Market Forecast
  • 5.2.6 Market Drivers and Limiters
• 5.3 Competitive Analysis
  • 5.3.1 Market Shares
  • 5.3.2 Competitor Discussions (in Alphabetical Order)
    • Concentric Medical
    • Penumbra
    • Other
    • 5.3.2.1 Emerging Competitors
      • Micrus Endovascular

APPENDIX A: MRG ACRONYMS AND INITIALISMS

APPENDIX B: SUPPLEMENTAL EXHIBITS

List of Exhibits

EXECUTIVE SUMMARY

• Exhibit 1: Clot Management Device Market, by Segment, US (US$), 2007 - 2013
• Exhibit 2: Thrombectomy Device Market, by Device Type, as a % of Total, US, 2008
• Exhibit 3: IVCF Market, by Device Type, as a % of Total, US, 2008
• Exhibit 4: Thrombolytic Infusion Catheter Market, US (US$), 2007 - 2013
• Exhibit 5: Neurovascular Embolectomies, US, 2007 - 2013
• Exhibit 6: Leading Competitors in the Clot Management Device Market, US, 2008

CHAPTER 1: US CLOT MANAGEMENT DEVICE MARKET

• Exhibit 7: Clot Management Device Market, US (US$), 2007 - 2013
• Exhibit 8: Arteriovenous Clot Management Procedures, by Type, US, 2008
• Exhibit 9: Peripheral Artery Clot Management Procedures, by Type, US, 2008
• Exhibit 10: Venous Clot Management Procedures, by Type, US, 2008
• Exhibit 11: PE Clot Management Procedures, by Type, US, 2008
• Exhibit 12: Coronary Clot Management Procedures, by Type, US, 2008
• Exhibit 13: Neurovascular Clot Management Procedures, by Type, US, 2008
• Exhibit 14: Clot Management Procedures, by Type, US, 2007 - 2013
• Exhibit 15: Clot Management Procedures, by Indication, US, 2007 - 2013
• Exhibit 16: Arteriovenous Clot Management Procedures, by Type, US, 2007 - 2013
• Exhibit 17: Peripheral Artery Clot Management Procedures, by Type, US, 2007 - 2013
• Exhibit 18: Venous Clot Management Procedures, by Type, US, 2007 - 2013
• Exhibit 19: PE Clot Management Procedures, by Type, US, 2007 - 2013
• Exhibit 20: Coronary Clot Management Procedures, by Type, US, 2007 - 2013
• Exhibit 21: Neurovascular Clot Management Procedures, by Type, US, 2007 - 2013
• Exhibit 22: Clot Management Device Market, by Segment, US (US$), 2007 - 2013 (Graphical Format)
• Exhibit 23: Clot Management Device Market, by Segment, US (US$), 2007 - 2013 (Tabular Format)
• Exhibit 24: Drivers of the Clot Management Device Market, US
• Exhibit 25: Limiters of the Clot Management Device Market, US
• Exhibit 26: Leading Competitors in the Clot Management Device Market, by Segment, as a % of Total, US, 2008

CHAPTER 2: THROMBECTOMY DEVICE MARKET

• Exhibit 27: Thrombectomy Device Market, US (US$), 2007 - 2013
• Exhibit 28: Thrombectomies, by Indication, US, 2007 - 2013 (Graphical Format)
• Exhibit 29: Thrombectomies, by Indication, US, 2007 - 2013 (Tabular Format)
• Exhibit 30: Peripheral Thrombectomies, by Indication, US, 2007 - 2013
• Exhibit 31: Peripheral Thrombectomies, by Indication and Device Type, US, 2007 - 2013
• Exhibit 32: Peripheral Thrombectomy Growth, by Indication and Device Type, US, 2008 - 2013
• Exhibit 33: Peripheral Thrombectomies, by Indication and Device Type, as a % of Total, US, 2007 - 2013
• Exhibit 34: Coronary Thrombectomies, by Device Type, US, 2007 - 2013
• Exhibit 35: ATTRACT Clinical Trial Summary, 2009
• Exhibit 36: Thrombectomy Device Market, by Device Type, as a % of Total, US, 2007 - 2013 (Graphical Format)
• Exhibit 37: Thrombectomy Device Market, by Device Type, US (US$), 2007 - 2013
• Exhibit 38: Thrombectomy Device Market Growth, by Device Type, US, 2008 - 2013
• Exhibit 39: Thrombectomy Device Market, by Device Type, as a % of Total, US, 2007 - 2013 (Tabular Format)
• Exhibit 40: Drivers of the Thrombectomy Device Market, US
• Exhibit 41: Limiters of the Thrombectomy Device Market, US
• Exhibit 42: Leading Competitors in the Thrombectomy Device Market, by Segment, as a % of Total, US, 2008

CHAPTER 3: INFERIOR VENA CAVA FILTER MARKET

• Exhibit 43: IVCF Market, US (US$), 2007 - 2013
• Exhibit 44: IVCF Placements, by Device Type, US, 2007 - 2013 (Graphical Format)
• Exhibit 45: IVCF Placements, by Device Type, US, 2007 - 2013 (Tabular Format)
• Exhibit 46: IVCF Placements, by Indication, US, 2007 - 2013
• Exhibit 47: IVCF Market, by Device Type, US (US$), 2007 - 2013 (Graphical Format)
• Exhibit 48: IVCF Market, by Device Type, US (US$), 2007 - 2013 (Tabular Format)
• Exhibit 49: IVCF Market Growth, by Device Type, US, 2008 - 2013
• Exhibit 50: IVCF Market, by Device Type, as a % of Total, US, 2007 - 2013
• Exhibit 51: Drivers of the IVCF Market, US
• Exhibit 52: Limiters of the IVCF Market, US
• Exhibit 53: Leading Competitors in the IVCF Market, by Device Type, as a % of Total, US, 2008

CHAPTER 4: THROMBOLYTIC INFUSION CATHETER MARKET

• Exhibit 54: Thrombolytic Infusion Catheter Market, US (US$), 2007 - 2013 (Graphical Format)
• Exhibit 55: CDT Procedures, by Indication, US, 2007 - 2013
• Exhibit 56: Inclusion Criteria for rt - PA Treatment in AIS, US
• Exhibit 57: Exclusion Criteria for rt - PA Treatment in AIS, by Type, US
• Exhibit 58: CaVenT Clinical Trial Summary, 2009
• Exhibit 59: IMS III Clinical Trial Summary, 2009
• Exhibit 60: SYNTHESIS EXP Clinical Trial Summary, 2009
• Exhibit 61: Thrombolytic Infusion Catheter Market, US (US$), 2007 - 2013 (Tabular Format)
• Exhibit 62: Drivers of the Thrombolytic Infusion Catheter Market, US
• Exhibit 63: Limiters of the Thrombolytic Infusion Catheter Market, US
• Exhibit 64: Leading Competitors in the Thrombolytic Infusion Catheter Market, as a % of Total, US, 2008

CHAPTER 5: NEUROVASCULAR EMBOLECTOMY DEVICE MARKET

• Exhibit 65: Neurovascular Embolectomy Device Market, US (US$), 2007 - 2013 (Graphical Format)
• Exhibit 66: MR RESCUE Clinical Trial Summary, 2009
• Exhibit 67: Penumbra Stroke Trial Summary, 2009
• Exhibit 68: Neurovascular Embolectomies, US, 2007 - 2013
• Exhibit 69: Neurovascular Embolectomies and Units, US, 2007 - 2013
• Exhibit 70: Neurovascular Embolectomy Device Market, US (US$), 2007 - 2013
• Exhibit 71: Drivers of the Neurovascular Embolectomy Device Market, US
• Exhibit 72: Limiters of the Neurovascular Embolectomy Device Market, US
• Exhibit 73: Leading Competitors in the Neurovascular Embolectomy Device Market, as a % of Total, US, 2008

APPENDIX B: SUPPLEMENTAL EXHIBITS

• Exhibit 74: Clot Management Device Market, by Segment, US (US$), 2007 - 2013 (Detailed Format)
• Exhibit 75: Thrombectomy Device Market, by Device Type, as a % of Total, US, 2008 (Detailed Format)
• Exhibit 76: IVCF Market, by Device Type, as a % of Total, US, 2008 (Detailed Format)
• Exhibit 77: Thrombolytic Infusion Catheter Market, US (US$), 2007 - 2013 (Detailed Format)
• Exhibit 78: Neurovascular Embolectomies, US, 2007 - 2013 (Detailed Format)