U.S and Western European Bone Graft Substitute Market

Table of Contents

• Declaration
• Research Scope
• Research Methodology

Chapter 1 Introduction

• Bone Grafting
• Biological Activity of Bone Grafts
• Current Bone Graft Technologies and Applications
• Autografts
  • Advantages of Autografts
  • Limitations of Autografts
• Machined Allografts
  • Advantages and Limitations of Machined Allografts
• Synthetic Bone Graft Substitutes
  • Advantages and Limitations of Synthetic Bone Grafts
• Demineralised Bone Matrices (DBMs)
  • Advantages and Limitations of DBMs
• Bone Morphogenic Proteins (BMPs)
  • Advantages and Limitations of BMPs
• Comparative Properties of Autografts and Allografts
• Comparative Properties of Synthetic Bone Graft Substitutes

Chapter 2 Orthopaedic Procedures and Bone Graft Utilisation

• Bone Graft Utilisation in Orthopaedic Applications (U.S., 2004)
• Total Number of Spinal Fusion Procedures in U.S., 2004
• Total Number of Spinal Fusion Procedures by Selected Geographic Regions in the U.S., 2004
• Total Number of Spinal Fusion Procedures by Anatomy, U.S., 2004
• Bone Graft Utilisation in Orthopaedic Applications (Western Europe, 2004)
• Total Number of Spinal Fusion Procedures in Western Europe, 2004
• Total Number of Spinal Fusion Procedures by Selected Geographic Regions in Western Europe, 2004
• Total Number of Spinal Fusion Procedures by Anatomy, Western Europe, 2004

Chapter 3 The Synthetic Bone Graft Substitutes Market

• Market Drivers and Restraints
• Industry Challenges
• Products
  • Calcibon
  • Calcibon Granules
  • Collapat II
  • Endobon
  • Calcigen S
  • Calcigen PSI
  • Pro-Osteon
  • Mimix and QuickSet Mimix
  • Norian SRS
  • ChronOS
  • CELLPLEX
  • OSTEOSET
  • MIIG 115 Minimally-Invasive Injectable Graft
  • MIIG X3 High Strength Injectable Bone Graft for Compression Fractures
  • Healos
  • Conduit TCP
  • JAX CS
  • JAX TCP
  • Cortoss
  • Vitoss
  • OsSatura TCP and OsSatura BCP
  • Stimulan
  • Allogran-N
  • Allogran-R
  • ApaPore
  • Pore-Si
  • Skelite
  • BioFuse
  • ReproBone
  • Polygraft BGS
  • NeuGraft Strip
  • ?-BSM
  • MBCP
  • Cerasorb
  • OpteMx
• Pricing Forecast for Synthetic Bone Graft Substitutes
  • Pricing Analysis
• U.S. and Western European Market Size for Synthetic Bone Graft Substitutes
  • Revenue Analysis
• U.S. Market Size for Synthetic Bone Graft Substitutes
  • Revenue Analysis
• Western European Market Size for Synthetic Bone Graft Substitutes
  • Revenue Analysis
• Western European Synthetic Bone Graft Substitutes Market by Geographic Region, 200
• Market Share, 2004

Chapter 4 Demineralised Bone Matrix (DBM) Market

• Market Drivers and Restraints
• Industry Challenges
  • Market Challenges
• Products
  • Dynagraft II Putty and Gel
  • Orthoblast II Putty and Gel
  • Accell Total Bone Matrix
  • Accell Connexus
  • Allomatrix Custom Bone Graft Putty
  • Allomatrix DR Graft
  • Allomatrix Injectable Putty
  • IGNITE ICS Graft
  • Osteoset 2 DBM Bone Graft Substitute with Bioassayed DBM
  • Grafton DBM Matrix PLF
  • Grafton DBM Crunch
  • Grafton DBM Matrix Plugs
  • Grafton DBM Flex
  • Grafton DBM Putty
  • Grafton DBM Gel
  • Grafton Plus DBM Paste
  • DBX Demineralised Bone Matrix Putty
  • InterGro DBM Putty
  • VIAGRAF DBM
  • Cellect
  • I/C Graft Chamber
  • Optium DBM Gel
  • Optium DBM Putty
  • Osteofil RT DBM Paste
  • Osteofil DBM Paste
  • Osteofil RT ICM Mouldable Allografts
  • Osteofil ICM Mouldable Strip
  • Osteofil IC Mouldable Allograft Syringe
  • Opteform
  • Optefil
  • Regenafil Allograft Paste
  • Regenaform Allograft Paste
• Pricing Forecast for DBM
  • Average Price Range of Various DBM Formulations
  • Pricing Analysis
• U.S. and Western European Market Size for DBM
  • Revenue Analysis
• U.S. Market Size for DBM
  • Revenue Analysis
• Western European Market Size for DBM
  • Revenue Analysis
  • Western European DBM Market by Geographic Region
• Distribution Structure
• Market Share
  • Market Share Analysis I
  • Market Share Analysis II

Chapter 5 Bone Morphogenic Proteins (BMP) Market

• Market Drivers and Restraints
• Market Opportunities
• End-User Trends
• Industry Challenges
  • Market Challenges
• BMP Products
  • rhBMP-2/ACS (marketed as InFUSE Graft in the U.S., and as InductOS in Europe)
    • History of rhBMP-2/ACS
    • Product Description
    • Development of rhBMP/ACS
    • Preclinical Studies
    • Clinical Studies
    • Indications and Contradictions
    • Development of InductOS in Europe
  • OP-1
    • Development of OP-1
    • Product Description
    • Preclinical Studies
    • Clinical Studies
    • FDA Indications and Contradictions
  • MP52
    • Product Description
    • History of Development
    • Preclinical and Clinical Studies
    • FDA Status
• Pricing Analysis
  • Pricing Forecasts for BMPs
• U.S. and Western European Market Size for BMPs
  • Revenue Analysis
• U.S. Market Size for BMPs
  • Revenue Analysis
• U.S. Unit Shipments of BMPs
  • Analysis of Unit Shipment of BMPs in the U.S
• Western European Market Size for BMPs
  • Revenue Analysis
• Western European Unit Shipments of BMPs
• Western European BMP Market by Geographic Region, 2004
• Surgeons Prospective