Abstract
Overview
Gene expression profiling methods enable the quantification of multiple
transcripts in a single RNA sample. Powerful and continually evolving methods,
such as microarray analysis, multiplex PCR and quantitative real-time RT-PCR,
are integral to deciphering the molecular mechanisms involved in development
and disease, and are important tools in the identification of new drug targets.
Percepta' s 2008 Gene Expression Profiling Dashboard™ dives deeply into
the characteristics and dynamics of the market for gene expression profiling
products. This 2008 Dashboard provides a snapshot of the current market
landscape that can be compared with data from the 2007 Gene Expression
Profiling Dashboard, providing an ongoing story of how the market is adapting
to new products, new competitors and new sales and marketing strategies.
The 2008 Gene Expression Profiling Dashboard™ was developed from
responses to a 21-question survey completed by 312 scientists predominantly
located in North America and Europe. 255 of these respondents perform gene
expression profiling methods on a regular basis. This Dashboard reveals key
market indicators for the gene expression profiling market as a whole as well
as for the following methods representing market sub-segments:
- Microarray-based gene expression studies
- Serial Analysis of Gene Expression (SAGE) studies
- Differential gene expression studies using multiplex PCR
- qRT-PCR (cDNA template) using gene specific fluorescent probe
- qRT-PCR (cDNA template) using non-specific SYBR Green
- Northern blot analysis
- Transcriptome studies using tiling arrays
- Transcriptome studies via short-read sequencing
Survey Methodology
In January of 2008, Percepta fielded the Gene Expression Profiling Survey to a
subset of the company' s panel of life scientists. Individuals were invited by
e-mail blast to click through to a webpage at bioanalytix.com where the survey
was hosted. Invitations were delivered on January 22, 2008 and results
collected through February 1. A total of 312 scientists completed the survey,
of which 255 are actively engaged in performing gene expression profiling
experiments. Results based on the aggregate of collected responses are
revealed in this Gene Expression Profiling Dashboard.
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