Table of Contents
Description of Chapters/Topics Covered
Chapter 1 Executive Summary
- Scope of this market report
- Developmental potential and epigenetic states of cells are intricately
linked
- Pluripotency - An eppigenetic phenomenon
- Epigenetic characteristics of somatic and pluripotent cells
- Proposed mechanisms of cellular reprogramming to create iPSCs
- Summary of epigenetic modifications and their effects
- Summary of technologies for assessing and profiling DNA methylation an
histone modifications
- Competitive landscape
Chapter 2 Epigenetics: Central and Essential Role in Differentiation and Disease
- Mechanisms and consequences of epigenetic modifications
- DNA and histone modifications that contribute to epigenetic regulation
- How epigenetic modifications affect gene expression
- Epigenetic aberrations in different diseases: Genes affected
Chapter 3 Epigenetics market landscape
- Epigenetics-based therapeutics
- HDAC inhibitors: Current status and research pipeline
- Emerging market trends in epigenetic therapeutics
- Epigenetics market landscape worldwide market survey: Data and analyses
- Qualitative market trends
- Quantitative market trends
Chapter 4 Pluripotency, hESCs, Reprogramming, iPSCs: Technical and Market Landscape
- iPSCs: Potential applications and limitations
- Small molecules and factors used in cellular reprogramming
- Methods of factor delivery for cellular reprogramming
- Pluripotency, hESCs, iPSCs market landscape worldwide market survey: Data
and analyses
- Qualitative market trends
- Quantitative market trends
- Usage pattern of various hESC lines from worldwide sources
Appendix 1. Research Methodology
Appendix 2. Global hESC Regulatory Landscape
Appendix 3. Pipeline of Epigenetics Therapeutics
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