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1 EXECUTIVE SUMMARY
- Overview and Perspective
- Overview
- The Technologies
- Scope and Methodology
- The Marketplace
- Market Analysis
- Barriers to Commercialization
2 INTRODUCTION TO GENE THERAPY AND DNA VACCINES
- The History of Gene Therapy
- The Beginning
- The Setbacks
- The Middle Ground
- Types of Technologies
- Retroviruses
- Adenoviruses
- Adeno-Associated Virus
- Naked DNA
- Chemical and Physical Methods
- Other Types of Technologies
- Alternatives to Gene Transfection
- Regulatory Factors
- RNA Inhibition
- Other Alternatives
3 GENE THERAPY MARKETS AND BARRIERS TO COMMERCIALIZATION
- Gene Therapy Market
- Gene Therapy Market
- Where to Focus
- Market Sectors that Will Be Affected by Gene Therapy
- Cancer
- Apoptosis-Modulating Therapies
- Ocular Disorders: Therapies for Macular Degeneration and Retinopathy
- Vaccines
- Diabetes Therapies
- Cystic Fibrosis Therapies
- Anti-TNF Therapeutics
- Rheumatoid Arthritis Therapies
- Biotech Drugs
- Blood Disorder and Products
- Other Sectors
- Barriers to Commercialization
- Barriers to Commercialization
- Economic Barriers
- Regulatory Barriers
- Gene Therapy in Europe: Lagging Behind
- Other Critical Barriers
4 TECHNOLOGY DEVELOPMENTS
- Vector and Gene-Transfer Technologies
- Mirus: Transport Genes to Intracellular Targets
- Genteric Inc: Gene Pills
- CytRx and Merck: Transfection Technology Brings Milestone Payment
- Purdue: RNA-ATP Motors As Gene Delivery Vehicles?
5 INTERNATIONAL INITIATIVES IN GENE THERAPY
- Research and Development in Europe
- Mologen: The New Minimalism?Tiny Cassette Combines Advantages of Plasmid and Viral Vectors
- Mologen: DNA Vaccine Against Leishmaniasis
- Mologen: Autologous Cancer Vaccine Looks Good in Clinical Trial
- Schering AG: Angiogenic Genes in Clinical Trials
- Transgene and Mirus: Vectors Pushed from Bloodstream into Muscle Tissue
- Transgene: Adenoviral Cancer Therapies Pass Phase I Trials
- Oxford BioMedica: DNA Vaccine for Cancer
- Ark Therapeutics: Viral Vector Gives TKO to Malignant Glioma
- Aventis: Angiogenesis and More
- European SPOTTY DOG Collaboration Targets Polymers
- Research and Development in Asia Pacific
- Mayne Pharma: Sheep Virus For Human Cancer Gene Therapy
- Takara Bio and MolMed: Suicide Genes for Cancer; and HIV Inhibition
- IC-Vec (Mitsubishi Chemical + Imperial College): An Improved Liposomal Vector System
- Tohoku University: Enzyme Gene Overcomes Chemotherapy Resistance
- Inovio AS and Australian Institute of Animal Science: Electroporation for DNA Vaccine Against Parasites
6 TECHNICAL INSIGHTS 2003 SCIENCE AND TECHNOLOGY AWARDS
- Product Innovation Award
- Award Description
- Award Recipient
- Technology Transfer Award
- Award Description
- Award Recipient
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