Drug Discovery--European Advances in Genomics and Proteomics

Table of Contents

1 EXECUTIVE SUMMARY

Introduction

• Introduction
• Genomics
• Proteomics
• Primary Applications: Drug Discovery and Molecular Diagnostics
• Market Trends

Scope and Methodology

• Scope
• Methodology

2 PRIMER ON GENOMICS AND PROTEOMICS TECHNOLOGIES

Genomics

• Introduction
• SNP Profiling
• Functional Genomics
• Structural Genomics
• Pharmacogenomics
• Toxicogenomics
• Chemical Genomics (Chemogenomics)

Proteomics

• Introduction
• Proteomics Techniques

Related Fields of Study

• Glycomics and Other "Omics"
• Systems Biology

3 APPLICATIONS ANALYSIS AND TRENDS

Genomics

• Drug Discovery
• Molecular Diagnostics

Proteomics

• Drug Discovery
• Molecular Diagnostics
• Antibodies as Therapeutics

4 NOTEWORTHY INNOVATION AT KEY ACADEMIC AND GOVERNMENT-RELATED INSTITUTIONS

Analysis and Ranking of Application Segments

• Introduction
• Regulatory Hurdles

Genomics

• DNA Chips
• Human Epigenome Project

Proteomics

• Protein Chips
• German Research Foundation To Establish Seven New Research Centers

5 NOTEWORTHY INNOVATION BY KEY COMPANIES

Genomics

• Pharmacogenomics
• Genome Sequencing
• Gene Expression
• Reverse Genomics
• Functional Genomics
• Applications
• Labeling and Detection Methods
• DNA Chips and Microarrays
• Chemical Genomics
• Additional Genomics Companies

Proteomics

• Protein Crystallography
• Spectroscopy
• Antibodies for Protein Identification; Auto-Immune Research
• Detection and Labeling
• Protein and Antibody Expression Systems
• Protein-Protein Interaction
• Protein chips
• Applications
• Additional Proteomics Companies

The Other ics

• Glycomics
• Bioinformatics

6 REGULATORY AND POLITICAL FACTORS

Government Guidelines and Support

• FDA Guidelines
• Governmental Support; Both Financial and IP Protection; Are Needed

Pharmaceutical Industry Response

• Pharmaceutical Industry Reluctance
• Fear of the New

7 INDUSTRY TRENDS

Market Trends

• Genomics
• Proteomics And Systems Biology

Enabling Technologies and Their Markets

• Electrophoresis and Proteome Informatics
• DNA and Protein Microarrays
• Spectroscopy and Chromatography
• Labs-on-a-Chip--Miniaturization Brings Higher Throughput with Less Sample
• Multiplexing and Biomarker-Based Diagnostics Market
• Automation
• New Tools for Genomics
• High-Throughput Screening Technologies Accelerate Drug Discovery

8 TECHNOLOGY ADOPTION FACTOR ANALYSIS

Technology Drivers

• Technology Features and Benefits
• Adoption Drivers for Genomics and Proteomics
• Analysis of Funding

Technology Restraints

• Technology or Product Development Restraints
• Competing Technologies and Complexity

9 CONTACTS AND PATENTS

Contacts

• European Companies
• Non-European Companies

Patents

• Patents--Section I
• Patents-- Section II

10 FROST & SULLIVAN 2005 SCIENCE AND TECHNOLOGY AWARDS

Technology Innovation

• Award Description
• Award Recipient

Technology Leadership

• Award Description
• Award Recipient

Product Leadership

• Award Description
• Award Recipient

11 DECISION SUPPORT DATABASE

Decision Support Database Relevant To This Study

• Government Healthcare Expenditure
• Private Healthcare Expenditure
• Total Healthcare Expenditure
• Government Biotech R&D Investments
• Private Biotech R&D Investments
• Pharma R&D Expenditure