Table of Contents
1. Overview
- 1.1 Statement of Report
- 1.2 About This Report
- 1.3 Scope of the Report
- 1.4 Objectives
- 1.5 Methodology
- 1.6 Executive Summary
2. Overview of Microarrays
- 2.1 History of Microarrays
- 2.2 Genomics and Proteomics
- 2.2.1 Genetic Variability and Disease
- 2.3 General Theory of Microarrays
- 2.4 DNA Microarrays
- 2.5 Protein Microarrays
- 2.6 Tissue Microarrays
3. DNA Microarrays
- 3.1 Advantages and Drivers
- 3.2 Limitations and Barriers to Commercialization
- 3.3 DNA Microarray Technology Platforms
- 3.3.1 Reasons Why Researchers Utilize DNA Microarrays
- 3.3.2 Factors for Difficulties Applying DNA Microarrays Technology
- 3.4 Key Attributes of DNA Microarray Software
- 3.5 Applications
- 3.6 Future Directions for DNA Microarray Technology
- 3.6.1 High-Throughput Array Technology
- 3.6.2 Emerging Microarray Trends
- 3.6.3 Emerging Microarray Applications
- 3.6.4 Key Points for Developing Microarray Based Applications
- 3.7 Competitive Landscape for DNA Microarrays
4. Protein Microarrays
- 4.1 Critical Factors for Microarray Content
- 4.2 Key Findings on Use of Microarrays
- 4.3 Advantages and Drivers
- 4.4 Limitations and Barriers to Commercialization
- 4.5 Key Experimental Parameters of Protein Microarray Technology for
Current and Future Users
- 4.6 Reasons Why Researchers Utilize Protein Microarrays
- 4.7 Factors for Adoption of Protein Microarrays Technology
- 4.8 Top Suppliers of Protein Microarray Slides and Products
- 4.9 Factors that Influence Sale Decisions
- 4.10 Future Innovations in Protein Microarray Technology
5. Current DNA Microarrays
- 5.1 Key Players
- 5.2.1 Microarray-Based Commercial Genotyping Activity
- 5.2.2 Location Analysis
- 5.3 Future Innovations in DNA Microarray Technology
6. Current Protein Microarrays
- 6.1 Protein Profiling Microarrays-Antibody Arrays
- 6.2 Protein Profiling Microarrays-Reverse Phase Microarrays
- 6.3 Multiplex Sandwich Microarrays-Planar
- 6.4 Multiplex Sandwich Immunoassays-Bead Based
- 6.5 Microarrays for Protein Function Studies
- 6.6 High Growth Applications
- 6.6.1 Cytokine Arrays
- 6.6.2 Whole Proteome Arrays
- 6.6.3 Microarray-Based Commercial Genotyping Activity
- 6.6.3.1 Microarray-Based Genotyping Applications
- 6.6.3.2 Microbial Applications
- 6.6.3.3 The Market for Microbial Genotyping Products
- 6.6.3.4 Comparative Genomic Hybridization (CGH)
- 6.6.4 ChIP-on-Chip Analysis
7. Technology
- 7.1 Production of Microarrays
- 7.2 2-D Versus 3-D Technology
- 7.3 Substrates and Surface Chemistries
- 7.4 Detection Methods
- 7.5 Instruments
- 7.6 Data Management and Informatics in Gene Expression
8. Applications
- 8.1 DNA Microarrays in Gene Expression
- 8.2 DNA Microarrays in SNP Analysis
- 8.3 DNA Microarrays in Cancer
- 8.4 Protein Expression
- 8.4.1 Cytokine Applications
- 8.4.2 Protein Function
- 8.4.3 Protein-Protein Interactions
- 8.5 Target /Biomarker Discovery
- 8.6 Drug Discovery and Development (Gene and Protein Microarrays)
- 8.7 Clinical Diagnostics (Gene and Protein Microarrays)
- 8.8 RNA Microarrays
- 8.9 Oligo Microarrays
- 8.10 Yeast Microarrays
- 8.11 Antibody Arrays
- 8.12 Arrays for Toxicogenomics
9. The Commercial Opportunity for Microarrays
- 9.1 Market Drivers for Microarrays
- 9.2 Market Restraints for Microarrays
- 9.3 Key Players
- 9.4 Market Size, Strategic Trends and Competitive Landscape for Protein
Arrays
- 9.5 Marketing and Distribution
- 9.6 Protein Arrays Market Analysis
- 9.7 Genes Associated with Major Diseases
- 9.8 Software and Data Analysis
- 9.8.1 Supplier of DNA Microarray Analysis Software
- 9.8.2 Satisfaction with Software Features
- 9.8.3 Satisfaction with Software
- 9.8.4 Supplier Factors in Software Purchase Decision
- 9.8.5 Suppliers' Role in Improving Data Sharing for DNA Microarrays
10. Company Profiles
LIST OF FIGURES
- Figure 6.1: Cytokines and Growth Factors: Sources of Microarrays for
Cytokine Research
- Figure 8.1: Microbial Genotyping: Applications for DNA Microarrays
- Figure 8.2: Source of Variation in Microarray Data
- Figure 8.3: Toxicogenomics: DNA Microarrays
LIST OF TABLES
- Table 3.1: Microarray Product Revenue: Arrays, Reagents and Instruments,
2005 and 2010
- Table 3.2: Microarray Market Drivers
- Table 3.3: Microarray Market Barriers
- Table 3.4: Unit Pricing of DNA Microarrays, 2000-2010
- Table 3.5: Steps in the Design and Implementation of a DNA Microarray
Experiment
- Table 3.6: Microarray Applications
- Table 3.7: List of DNA Array Manufacturers
- Table 4.1: Critical Factors for Microarray Content
- Table 4.2: Top Three Suppliers of Treated Protein Microarray Surfaces for
Self-Printing
- Table 4.3: Top Suppliers of Commercially Available Protein Microarrays
- Table 4.4: Top Suppliers of Protein Microarray Readers
- Table 5.1: Affymetrix Sales of Probe Arrays, 2000-2007
- Table 5.2: Affymetrix Total Product Sales, 1999-2007
- Table 5.3: Affymetrix Instrument Sales, 2000-2007
- Table 6.1: Microarray Genetic Testing
- Table 6.2: ChIP-on-Chip Microarray Market Size Projections, 2005-2011
- Table 8.1: Applications of Biochips by Class
- Table 8.2: Diagnostics Microarray Market Size Projections, 2005-2011
- Table 8.3: HTS Microarray Market Size Projections, 2005-2011
- Table 8.4: Pharmacogenomics Microarray Market Size Projections, 2005-2011
- Table 8.5: Toxicology Screening Microarray Market Size Projections,
2005-2011
- Table 8.6: Expression Profiling Microarray Market Size Projections,
2005-2011
- Table 9.1: Market Share of Microarray Products, 2006
- Table 9.2: Affymetrix Product Sales
- Table 9.3: Leading Microarray Companies
- Table 9.4: Worldwide Microarray Market Size, 2004-2012
- Table 9.5: Microarray Market Share by Technology Type
- Table 9.6: DNA Microarray U.S. Market Size, 2005-2011
- Table 9.7: DNA Microarray Worldwide Market Size, 2002-2011
- Table 9.8: Biochip Market by Usage, 2003 and 2007
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