Bioinformatics Markets

Table of Contents

1. Overview

• 1.1 Statement of Report
• 1.2 About this Report
• 1.3 Scope of this Report
• 1.4 Methodology
• 1.5 Executive Summary

2. Introduction

• 2.1 Global Bioinformatics Products Industry
• 2.2 Computers and Biology
• 2.3 Bioinformatics and the Internet
• 2.4 Company Evaluation Overview
• 2.5 Market Outlook
• 2.6 Competitive Structure
• 2.7 Applications of Bioinformatics
  • 2.7.1 Medicine
  • 2.7.2 Microbial Genomics
  • 2.7.3 Agriculture
• 2.8 R&D
  • 2.8.1 Allocation of R&D
  • 2.8.2 Traditional Drug Discovery Process
  • 2.8.3 Drug Discovery and Bioinformatics
• 2.8.4 Collaborative Agreements
• 2.9 The Human Genome Project (HGP)
  • 2.9.1 Goals of the Human Genome Project
  • 2.9.2 Benefits of the Human Genome Project
• 2.10 Barriers to Entry
• 2.11 Proteomics and Databases
  • 2.11.1 Protein Database Standards
  • 2.11.2 Future Trends

3. The U.S. Bioinformatics Market

• 3.1 Overview
• 3.2 Market Restraints and Drivers
  • 3.2.1 Market Restraints
  • 3.2.2 Market Drivers

4. Genomics

• 4.1 The Biotechnology Industry
• 4.2 The Development of a Genomics Market
  • 4.2.1 Market Drivers
  • 4.2.2 Market Restraints
  • 4.2.3 Market Size and Growth Projections
  • 4.2.4 The U.S. Genomics Market
• 4.3 Biochips and DNA Microarrays
  • 4.3.1 Key Challenges
  • 4.3.2 Freeware
  • 4.3.3 New Tools
• 4.4 Bioinformatics
• 4.5 Disease Targets
• 4.6 Functional Genomics
• 4.7 Gene Sequencing
• 4.8 Gene Sequence Variation Detection
• 4.9 Comparative Genomics
• 4.10 Genome Database Arrays
• 4.11 High-throughput Genomics
  • 4.11.1 High-throughput Technology
  • 4.11.2 Lab on a Chip
• 4.12 Pharmacogenomics
• 4.13 Probe Arrays
  • 4.13.1 Gene Expression Monitoring Arrays
  • 4.13.2 DNA Analysis Arrays
• 4.14 Proteomics
• 4.15 Sequencing
• 4.16 Single Nucleotide Polymorphisms (SNPs)
• 4.17 Structural Genomics
• 4.18 Photolithography
• 4.19 Instrumentation

5. The Bioinformatics Industry

• 5.1 Definition and Role of Bioinformatics
  • 5.1.1 Bioinformatics Sector Overview
  • 5.1.2 The Future Status of Bioinformatics
  • 5.1.3 Barriers to Growth
• 5.2 Types of Data and Bioinformatics Applications
  • 5.2.1 Validated Core Modeling Technology
  • 5.2.2 Broad Applicability
  • 5.2.3 Data Management Compliant with Industry Standards
  • 5.2.4 Open Architecture
  • 5.2.5 Ease of Use
  • 5.2.6 Increased Access
• 5.3 Functions of Bioinformatics Software
  • 5.3.1 Data Management
  • 5.3.2 Data Transformation
  • 5.3.3 Data Collaboration
  • 5.3.4 Interface for Online Data Sources
• 5.4 Target Markets for Informatics Software
• 5.5 Steps Involved in Bringing a Drug to Market
• 5.6 Costs Incurred in Developing a New Drug
• 5.7 Industry Drivers and Challenges
• 5.8 Industry Risks
• 5.9 Products of Bioinformatics
• 5.10 Bioinformatics Processes
• 5.11 Informatics Tools and Functionalities
  • 5.11.1 Sequence to Structure
  • 5.11.2 Lead Identification and Optimization
  • 5.11.3 Development and Formulation
  • 5.11.4 Improving Materials and Processes
  • 5.11.5 Other Materials-Based Industries
• 5.12 Role of Bioinformatics in the Biotechnology Value Chain
• 5.13 Bioinformatics Market Segment
  • 5.13.1 Databases
  • 5.13.2 Hardware
  • 5.13.3 Software
  • 5.13.4 Bioinformatics Services
• 5.14 Bioinformatics Market Size
  • 5.14.1 Sales and R&D
  • 5.14.2 IT Budget
  • 5.14.3 Projected Bioinformatics Market Size
• 5.15 Global Market Perspective

6. Bioinformatics Business

• 6.1 Bioinformatics Business Models
  • 6.1.1 Changing Business Models
  • 6.1.2 Competition for Pure Play Informatics Companies
  • 6.1.3 Non-Profit Organizations
  • 6.1.4 In-House Bioinformatics Solutions
  • 6.1.5 Large IT Companies
• 6.2 Bioinformatics Target Disciplines
  • 6.2.1 Comparative Genomics
  • 6.2.2 Pharmacogenomics
  • 6.2.3 Functional Genomics
  • 6.2.4 Proteomics
  • 6.2.5 Structural Genomics
  • 6.2.6 Image Informatics
  • 6.2.7 Clinical Trial Informatics
  • 6.2.8 Cheminformatics
• 6.3 Bioinformatics Architecture
• 6.4 Bioinformatics Applications
  • 6.4.1 Data Search Tools
  • 6.4.2 Data Visualization Tools
  • 6.4.3 Data Mining and Clustering
  • 6.4.4 Enterprise Solutions
  • 6.4.5 Data Warehousing
• 6.5 Evaluation of Bioinformatics Solutions
  • 6.5.1 Requirements of Study
  • 6.5.2 Shortlisting the Options
  • 6.5.3 Scoring Patterns
  • 6.5.4 Performance
  • 6.5.5 Data Storage
  • 6.5.6 Data Management in Drug Discovery
  • 6.5.7 Key Issues in Bioinformatics Data Storage
• 6.6 Convergence of Industries
• 6.7 Proteins as a Driver
• 6.8 Current Bioinformatics Research
• 6.9 New Bioinformatics Modeling Algorithms
• 6.10 3D Modeling
• 6.11 Patenting Bioinformatics Algorithms

7. Recent Industry Activity

• 7.1 Collaborations and Acquisitions
• 7.2 Product Development and Launches

8. Corporate Profiles

• 8.1 Abbott Laboratories
• 8.2 Abgenix
• 8.3 Ablynx
• 8.4 Accelrys
• 8.5 Affimed Therapeutics
• 8.6 Affitech
• 8.7 Affymetrix
• 8.8 Agencourt Bioscience Corporation
• 8.9 Agensys
• 8.10 Agilent Technologies
• 8.11 Alexion Pharmaceuticals
• 8.12 AlgoNomics
• 8.13 ALLEZ Software
• 8.14 Amgen
• 8.15 Antisoma
• 8.16 Applied Biosystems
• 8.17 Arana Therapeutics
• 8.18 Ariadne Genomics
• 8.19 Array Genetics
• 8.20 Astellas Pharma
• 8.21 AstraZeneca
• 8.22 Automated Handling Systems
• 8.23 Avesthagen, Limited
• 8.24 Bioalma
• 8.25 BIOBASE Biological Databases
• 8.26 BioCarta
• 8.27 Biodatabases (AMITA Corporation)
• 8.28 BioDiscovery
• 8.29 Biogen Idec
• 8.30 BioInformatics
• 8.31 BioInformatics Services
• 8.32 BioInformatics Solutions
• 8.33 Biomax Informatics
• 8.34 BioServe Technologies
• 8.35 Biosiris
• 8.36 BioSoftSolutions
• 8.37 Biotique Systems
• 8.38 BioInvent International
• 8.39 Biosite Discovery
• 8.40 BioWa
• 8.41 BioWisdom
• 8.42 Bio-Xtal
• 8.43 Boehringer Ingelheim
• 8.44 Cambridge Antibody Technology Group
• 8.45 Capital Genomix
• 8.46 Celera Group
• 8.47 Cellectis
• 8.48 Cellomics
• 8.49 CeuticalSoft
• 8.50 Chemical Computing Group
• 8.51 Cimarron Software
• 8.52 CLONDIAG Chip Technologies
• 8.53 CodonCode Corporation
• 8.54 CompuDrug International
• 8.55 Compugen USA
• 8.56 Corimbia
• 8.57 Crucell
• 8.58 CSIRO Bioinformatics
• 8.59 CuraGen Corporation
• 8.60 CyberGene
• 8.61 Cytogen
• 8.62 Data Unlimited International
• 8.63 deCODE Genetics
• 8.64 Decodon
• 8.65 Deltagen
• 8.66 Digilab
• 8.67 DNA Software
• 8.68 DNAPrint Genomics
• 8.69 DNA Star
• 8.70 DxS
• 8.71 Dyax Corp.
• 8.72 Eisai
• 8.73 Elan Corporation
• 8.74 Electric Genetics Corporation
• 8.75 Elusys Therapeutics
• 8.76 Entagen
• 8.77 Entelos
• 8.78 Enzon Pharmaceuticals
• 8.79 Epigenomics
• 8.80 ePitope Informatics
• 8.81 EraGen Biosciences
• 8.82 European Bioinformatics Institute (EBI) Industry Programme
• 8.83 Evolutionary BioInformatics
• 8.84 Genamics
• 8.85 GeneData
• 8.86 Gene Logic
• 8.87 Genentech
• 8.88 Geneva Bioinformatics (GeneBio)
• 8.89 Genmab
• 8.90 GenOdyssee
• 8.91 Genolyze
• 8.92 Genomatica
• 8.93 GenomeQuest
• 8.94 Genomic Solutions
• 8.95 Genomining
• 8.96 Genovac
• 8.97 Genzyme
• 8.98 Geospiza
• 8.99 GlaxoSmithKline
• 8.100 Glycominds
• 8.101 Health Discovery Corporation
• 8.102 Hitachi Corporate Technology Group
• 8.103 IBM Life Sciences
• 8.104 ImClone Systems
• 8.105 ImmunoGen
• 8.106 Immunomedics
• 8.107 Improved Outcomes Software
• 8.108 INCOGEN
• 8.109 Incyte Corporation
• 8.110 Informagen
• 8.111 Ingenuity Systems
• 8.112 InNexus Biotechnology
• 8.113 Insilicos
• 8.114 Intrexon Corporation
• 8.115 Invitrogen Corporation
• 8.116 IO Informatics
• 8.117 Johnson & Johnson
• 8.118 LabVantage Solutions
• 8.119 Lexigen
• 8.120 Lifespan Biosciences
• 8.121 Lion Bioscience
• 8.122 MathEcology
• 8.123 Matrix Science
• 8.124 Medarex
• 8.125 Medicel
• 8.126 MedImmune
• 8.127 Merus
• 8.128 METabolic Explorer
• 8.129 Metahelix Life Sciences
• 8.130 Metalife
• 8.131 Micromet
• 8.132 Millennium Pharmaceuticals
• 8.133 Molecular Connections
• 8.134 Molecular Networks
• 8.135 Molecularware
• 8.136 MorphoSys
• 8.137 Nexus Genomics
• 8.138 Nonlinear Dynamics
• 8.139 Novartis
• 8.140 Ocimum Biosolutions
• 8.141 OmniViz
• 8.142 Partek
• 8.143 PDL BioPharma
• 8.144 Perlegen Sciences
• 8.145 Philogen
• 8.146 Philotec
• 8.147 Prokaria
• 8.148 Quantiom Bioinformatics
• 8.149 Relevant Software
• 8.150 Roche
• 8.151 Rosetta Inpharmatics
• 8.152 Sanofi-Aventis
• 8.153 SBI Science
• 8.154 Seascape Learning
• 8.155 Seattle Genetics
• 8.156 Scil Proteins
• 8.157 Simulations Plus
• 8.158 Spotfire
• 8.159 Strand Life Sciences
• 8.160 Sun Microsystems
• 8.161 Symphogen
• 8.162 Syngene
• 8.163 Tahoe Informatics
• 8.164 Tanox
• 8.165 3rd Millennium
• 8.166 ThromboGenics
• 8.167 Thomson Reuters
• 8.168 TIB MOLBIOL
• 8.169 Trion Pharma
• 8.170 Tripos
• 8.171 UBI Life Sciences
• 8.172 Viventia Biotech
• 8.173 VizX Labs
• 8.174 Wyeth
• 8.175 Xcellerex
• 8.176 Xencor
• 8.177 Xoma
• 8.178 Xpogen

INDEX OF FIGURES

• Figure 4.1: Representation of Biotechnology Market, Geographically, 2008
• Figure 5.1: Informatics Applications along the Drug-Discovery Value Chain
• Figure 5.2: Functions of Bioinformatics Software in Research
• Figure 5.3: EMBL Database Growth, 1995-2008
• Figure 5.4: The Steps Involved in Bringing a Drug to Market
• Figure 5.5: The Breakdown of Total Costs in New Drug Development, 2007
• Figure 5.6: The Role of Bioinformatics in the Biotechnology Value Chain
• Figure 5.7: Worldwide Pharmaceutical Sales and R&D Expenditures, 2000-2013
• Figure 5.8: Worldwide Growth in IT Budget, 2000-2013
• Figure 5.9: Worldwide Bioinformatics Market, 2000-2013
• Figure 6.1: Steps of a Proteomics Experiment
• Figure 6.2: Bioinformatics Architecture

INDEX OF TABLES

• Table 2.1: Leading Biotechnology Companies
• Table 2.2: Total of Domestic U.S. R&D, 2006-2013
• Table 2.3: Global Biotechnology Market, 2007
• Table 2.4: SIB Informatics Databases
• Table 4.1: The U.S. Biotechnology Industry Size and Revenue, 2000-2007
• Table 4.2: Global Biotechnology Industry Major Segments
• Table 4.3: Genomics Sector Market Size, 2006-2013
• Table 4.4: Total Biochip Market, 2007-2013
• Table 4.5: Selected Competitors in the Biochip Market
• Table 4.6: Biochip Microarray Products
• Table 4.7: Bioinformatics Tools
• Table 4.8: Functional Genomics Companies Building Advanced Integrated Platforms and Substantial Databases
• Table 4.9: Companies Using New Genomic Tools
• Table 4.10: Non-DNA-Based Chip Suppliers
• Table 4.11: Robotics or "Lab-on-a-Chip" Market Sector
• Table 4.12: Key High-throughput and Systemic Approaches in Genomic Analysis
• Table 4.13: Pharmacogenomics Segment Players
• Table 4.14: The Worldwide Market for Pharmacogenomics, 2006-2013
• Table 4.15: Competitors in the SNP Genotyping Segment
• Table 4.16: Scanning and Detection Technology Suppliers
• Table 5.1: Data Sources and Bioinformatic Investigations
• Table 5.2: Drivers and Challenges of the Bioinformatics Industry
• Table 5.3: Bioinformatics Activities, Sub-Activities and Key Players
• Table 5.4: Bioinformatics Market Size, 2006-2013
• Table 5.5: Cheminformatics Market Size, 2006-2013
• Table 5.6: In-silico Informatics Market Size, 2006-2013
• Table 5.7: Bioinformatics Hardware and Systems Market Size, 2006-2013
• Table 6.1: Alliances between IT/Telecom and Biotechnology Firms
• Table 6.2: Types of Intellectual Property Protection for Bioinformatics Tools