Pre-clinical Stage Partnering Agreements in Biopharma

Table of Contents

Executive Summary

Chapter 1 - Introduction

Chapter 2 - Trends in pre-clinical stage dealmaking

• 2.1. Introduction
• 2.2. Difference between lead and pre-clinical compound deals
  • 2.2.1. Trends in pre-clinical stage deals since 2000
  • 2.2.2. Attributes of pre-clinical stage deals
• 2.3. Reasons for entering into pre-clinical stage partnering deals
  • 2.3.1. Licensors reasons for entering pre-clinical stage deals
  • 2.3.2. Licensees reasons for entering pre-clinical stage deals
• 2.4. The future of pre-cliincal stage partnering deals

Chapter 3 - Overview of pre-clinical stage deal structure

• 3.1. Introduction
• 3.2. The anatomy of a pre-clinical stage deal
  • 3.2.1. Example pre-clinical stage agreements
  • 3.2.1.a. Case study 1: Tracon - Cell Matrix - Cancervax - March 2007
  • 3.2.1.b. Case study 2: Pfizer - InSite Vision - February 2007

Chapter 4 - Leading pre-clinical stage deals

• 4.1. Introduction
• 4.2. Top pre-clinical stage deals by value
• 4.3. Top pre-clinical stage deals signed by bigpharma
• 4.4. Most active pre-clinical stage dealmakers
• 4.5. Bigpharma pre-clinical stage deal activity

Chapter 5 - Bigpharma pre-clinical stage partnering agreements

• 5.1. Introduction
• 5.2. How to use pre-clinical stage partnering agreements
• 5.3. Company pre-clinical stage partnering agreement listings
  • Abbott
  • Actavis
  • Alcon Labs
  • Allergan
  • Amgen
  • Astellas
  • AstraZeneca
  • Barr Pharmaceuticals
  • Baxter International
  • Bayer
  • Biogen Idec
  • Boehringer Ingelheim
  • Bristol-Myers Squibb
  • Chugai
  • CSL
  • Daiichi Sankyo
  • Eisai
  • Eli Lilly
  • Forest Laboratories
  • Genentech
  • Genzyme
  • Gilead Sciences
  • GlaxoSmithKline
  • Johnson & Johnson
  • King
  • Lundbeck
  • Menarini
  • Merck & Co
  • Merck - Serono KGaA
  • Mitsubishi
  • Mundipharma
  • Novartis AG
  • Novo Nordisk
  • Nycomed Pharma
  • Otsuka
  • Pfizer
  • Procter & Gamble
  • Ratiopharm
  • Roche
  • Sanofi-Aventis
  • Schering Plough
  • Servier
  • Shire
  • Solvay
  • Stada
  • Takeda
  • Teva
  • UCB
  • Watson
  • Wyeth

Chapter 6 - Pre-clinical partnering agreement directory 2003-mid 2008

• 6.1. Introduction
• 6.2. Company A-Z
• 6.3. By therapy area
  • Accident/Hospital/Trauma
  • Blood/Lymphatic System
  • Cardiovascular
  • Central nervous System
  • Dermatology
  • Gastrointestinal
  • Genetic
  • Genitourinary
  • Autoimmune/Inflammatory
  • Infection
  • Metabolism
  • Musculoskeletal
  • Oncology
  • Respiratory
  • Sensory Organ / Oral Health
  • Delivery
• 6.4. By deal type
  • Collaborative R&D
  • Co-development
  • Co-marketing
  • Co-promotion
  • Development
  • Distribution
  • Joint venture
  • Licensing
  • M&A
  • Manufacturing
  • Marketing
  • Promotion
  • Research
  • Supply

Appendices

• Appendix 1 - Pre-clinical stage partnering references
• Appendix 2 - Resources
• Appendix 3 - Deal type definitions
• Appendix 4 - Example pre-clinical stage partnering contract
• About CurrentPartnering
• Recent report titles from CurrentPartnering
• Order Form - Reports
• Order Form - Company Partnering Guides available

Table of figures

• Figure 1: Definition of lead and pre-clinical compound dealmaking
• Figure 2: Trends in pre-clinical stage deal announcements, 2000-2007
• Figure 3: Components of the pre-clinical deal structure
• Figure 4: Top pre-clinical stage deals by value since 2003
• Figure 5: Bigpharma - top 50 - pre-clinical stage deals since 2003
• Figure 6: Most active pre-clinical stage dealmakers 2003-mid 2008
• Figure 7: Bigpharma - top 50 - pre-clinical stage deals since 2003
• Figure 8: Online partnering resources
• Figure 9: Deal type definitions
• Figure 10: Partnering agreement between and Merck KGaA and Idera Pharmaceuticals - December 2007