Protein Chips: Where To?

INTRODUCTION

• STUDY GOALS AND OBJECTIVES
• REASONS FOR DOING THE STUDY
• AUDIENCE FOR THE REPORT
• SCOPE AND FORMAT
• METHODOLOGY AND INFORMATION SOURCES
• BCC INFORMATION AND RELATED BCC STUDIES
• ANALYST CREDENTIALS
• DISCLAIMER
• BCC ON-LINE SERVICES

EXECUTIVE SUMMARY

Summary Table:
WORLDWIDE PROTEIN ARRAY TECHNOLOGY SALES BY MARKET SEGMENT, THROUGH 2007 ($ MILLIONS)

Summary Figure:
WORLDWIDE PROTEIN ARRAY TECHNOLOGY SALES BY MARKET SEGMENT, 2000-2007 ($ MILLIONS)

OVERVIEW

• WHICH IS THE CHICKEN, WHICH IS THE EGG: PROTEOMICS OR PROTEIN ARRAYS?
• ARRAY-BASED PROTEOMICS GLOSSARY
  • ARRAY-BASED PROTEOMICS GLOSSARY (CONTINUED)
  • ARRAY-BASED PROTEOMICS GLOSSARY (CONTINUED)
  • ARRAY-BASED PROTEOMICS GLOSSARY (CONTINUED)
  • ARRAY-BASED PROTEOMICS GLOSSARY (CONTINUED)

PROTEIN ARRAY TECHNOLOGY

• SURFACES
• ATTACHMENT CHEMISTRY
• ARRAYING DEVICES
• DETECTION AND ANALYSIS ON MICROARRAYS
• CAPTURE MOLECULES

Table 1 PROTEIN CAPTURE MOLECULES AND TARGETS

• PROTEIN PRODUCTION FOR PROTEIN ARRAYS
• PROTEIN ARRAY APPLICATIONS
  • DIAGNOSTICS
  • PROTEOME RESEARCH
  • DRUG DISCOVERY AND SCREENING

GOVERNMENT REGULATIONS

• DRUG DISCOVERY PROCESS
  • FDA REGULATORY OVERVIEW
    • Target Discovery and Drug Identification
    • Preclinical Testing and Submission of an IND
    • Clinical Trials
    • Submission of an NDA
    • Post-FDA Approval
    • Noncompliance
  • OTHER AGENCY REGULATIONS
  • REGULATORY COSTS
  • REGULATORY BENEFITS
  • RESEARCH AND DEVELOPMENT SPENDING

Table 2 R&D SPENDING IN THE GLOBAL PHARMACEUTICAL INDUSTRY, 1980-2002 ($ MILLIONS)

• Distribution of Research Costs

Table 3 DISTRIBUTION OF DRUG RESEARCH COSTS

• Target Discovery Costs and Benefits
• REGULATORY ENVIRONMENT AND R&D COST CUTTING
  • Preliminary Stage R&D Cost Reduction
• NEW DRUG APPROVALS

Table 4 DRUGS APPROVED BY THE FDA, 1993-2002 (# DRUGS)

• CLINICAL DIAGNOSTICS
  • FEDERAL REGULATION OF MOLECULAR DIAGNOSTICS
    • Analyte-Specific Reagent Regulations
      • Analyte-Specific Reagent Regulations (Continued)

PROTEOME CONSORTIUMS

• BIOPATHWAYS CONSORTIUM
  • BIOLOGICAL PATHWAY EXCHANGE
• PLASMA PROTEOME INSTITUTE
• HUMAN PROTEOME ORGANIZATION
  • THE PROTEOMICS STANDARDS INITIATIVE
• THE PROTEOME SOCIETY

PROTEIN ARRAY TECHNOLOGY MARKET

• MARKET SEGMENTS

Table 5 PROTEIN ARRAY TECHNOLOGY COMPANIES AND MARKET SHARES, BY CATEGORY, 2002

• TECHNOLOGY TRENDS
• MARKET FORECASTS
  • SALES AND MARKET SHARE
  • GROWTH RATE

Table 6 WORLDWIDE PROTEIN ARRAY TECHNOLOGY SALES BY CATEGORY, THROUGH 2007 ($ MILLIONS)

• DISTRIBUTION OF COMPANIES BY SEGMENT

Table 7 WORLDWIDE DISTRIBUTION OF PROTEIN ARRAY TECHNOLOGY COMPANIES BY CATEGORY, 2002

• COMPANY PRODUCT LAUNCHES

Table 8 COMPANIES WORLDWIDE THAT LAUNCHED PROTEIN ARRAY TECHNOLOGY PRODUCTS, BY CATEGORY, 1999-2002

Table 9 PROTEIN ARRAY TECHNOLOGY PRODUCT LAUNCHES, BY CATEGORY, 2002 (%)

• ANTIBODY ARRAYS

Table 10 COMPANIES THAT LAUNCHED ANTIBODY ARRAY PRODUCTS, 1999-2002

• SALES

Table 11 WORLDWIDE ANTIBODY ARRAY TECHNOLOGY SALES, THROUGH 2007 ($ MILLIONS)

Figure 1 WORLDWIDE ANTIBODY ARRAY TECHNOLOGY SALES, 2000-2007 ($ MILLIONS)

• ANTIBODY ARRAY PLAYERS

Table 12 ANTIBODY ARRAY TECHNOLOGY PRODUCT LAUNCHES, BY COMPANY, 2000-2002

• ANTIBODY ARRAY TECHNOLOGY

Table 13 SUMMARY OF ANTIBODY ARRAY TECHNOLOGY FEATURES, BY COMPANY

• Surface Materials

Table 14 ANTIBODY ARRAY SURFACE MATERIAL USE, BY TYPE, 2002

• Detection Methods

Table 15 ANTIBODY ARRAY DETECTION METHOD USE BY TYPE, 2002

• ANTIBODY ARRAY MARKET SHARE

Table 16 ANTIBODY ARRAY TECHNOLOGY COMPANY MARKET SHARE, 2002

Figure 2 ANTIBODY ARRAY TECHNOLOGY COMPANY MARKET SHARE, 2002 (%)

• Schleicher & Schuell Bioscience, Inc.
• RayBiotech
• Panomics
• Pierce Chemical Company
• BD Clontech
• Hypromatrix
• Milagen
• OTHER ANTIBODY ARRAY DEVELOPMENTS
• TYPES/APPLICATIONS OF ANTIBODY ARRAYS

Table 17 APPLICATIONS/TYPES OF ANTIBODY ARRAY TECHNOLOGY, BY COMPANY

• PEPTIDE BIOCHIP ARRAYS
  • SALES

Table 18 WORLDWIDE PEPTIDE BIOCHIP ARRAY TECHNOLOGY SALES, THROUGH 2007 ($ MILLIONS)

Figure 3 WORLDWIDE PEPTIDE BIOCHIP ARRAY TECHNOLOGY SALES, 2000-2007 ($ MILLIONS)

Table 19 PEPTIDE ARRAY PRODUCT LAUNCHES, 1999-2002

• PEPTIDE CHIP TECHNOLOGY PLAYERS

Table 20 PEPTIDE BIOCHIP TECHNOLOGY LAUNCHES BY COMPANY, 2000-2004

• PEPTIDE BIOCHIP TECHNOLOGY

Table 21 PEPTIDE BIOCHIP TECHNOLOGY FEATURES, BY COMPANY

• Surface Materials

Table 22 PEPTIDE ARRAY SURFACE MATERIAL USE, BY COMPANY

• Detection Methods

Table 23 PEPTIDE ARRAY DETECTION METHOD BY COMPANY

• PROTEIN BIOCHIP ARRAYS
  • SALES

Table 24 WORLDWIDE PROTEIN BIOCHIP ARRAY TECHNOLOGY SALES, THROUGH 2007 ($ MILLIONS)

Figure 4 WORLDWIDE PROTEIN BIOCHIP ARRAY TECHNOLOGY SALES, 2000-2007 ($ MILLIONS)

Table 25 PROTEIN BIOCHIP TECHNOLOGY COMPANIES

• PROTEIN BIOCHIP ARRAY PLAYERS

Table 26 COMPANIES THAT LAUNCHED PROTEIN BIOCHIPS, 1999-2002

Table 27 PROTEIN BIOCHIP PRODUCT LAUNCHES BY COMPANY, 1999-2002

• PROTEIN BIOCHIP ARRAY TECHNOLOGY

Table 28 PROTEIN BIOCHIP ARRAY PRODUCTS/SERVICES FEATURES BY COMPANY

Table 28 (CONTINUED)

• PROTEIN BIOCHIP ARRAY MARKET SHARE

Table 29 PROTEIN BIOCHIP ARRAY TECHNOLOGY COMPANY MARKET SHARES, 2002 (%)

Figure 5 PROTEIN BIOCHIP ARRAY TECHNOLOGY COMPANY MARKET SHARES, 2002 (%)

• COMPANIES DEVELOPING PROTEIN BIOCHIP ARRAY TECHNOLOGY

Table 30 COMPANIES WITH PROTEIN BIOCHIP ARRAY TECHNOLOGY IN DEVELOPMENT

Table 30 (CONTINUED)

Table 30 (CONTINUED)

• Molecular Staging, Inc.
• Somalogic, Inc.
• Zeptosens AG
• Protein Biochip Array Surface Materials

Table 31 PROTEIN BIOCHIP ARRAY SURFACE MATERIAL USE, BY TYPE, 2002

Table 32 PROTEIN BIOCHIP ARRAY SURFACE MATERIAL DESCRIPTION, BY COMPANY

• Protein Biochip Array Detection Technology

Table 33 PROTEIN BIOCHIP ARRAY DETECTION METHOD USE BY TYPE, 2002

Table 34 PROTEIN BIOCHIP ARRAY DETECTION METHOD DESCRIPTION, BY COMPANY

Table 34 (CONTINUED)

• Randox Laboratories, Ltd.
• SOLUTION BEAD/PARTICLE PROTEIN ARRAYS

Table 35 SOLUTION BEAD/PARTICLE PROTEIN ARRAY TECHNOLOGY SALES, 2000-2007 ($ MILLIONS)

Figure 6 SOLUTION BEAD/PARTICLE PROTEIN ARRAY TECHNOLOGY SALES, THROUGH 2007 ($ MILLIONS)

• SOLUTION BEAD/PARTICLE TECHNOLOGY PLAYERS

Table 36 SOLUTION BEAD/PARTICLE PROTEIN ARRAY TECHNOLOGY COMPANIES

• SOLUTION BEAD/PARTICLE TECHNOLOGY PLAYERS

Table 37 SUMMARY OF SOLUTION BEAD/PARTICLE PROTEIN ARRAY TECHNOLOGY FEATURES BY COMPANY

• Nanoplex Nanobar
• Polymer Bead/Semi-Conductor Core Shell
• Smartbead™

Table 38 SOLUTION BEAD/PARTICLE PROTEIN ARRAY MATERIAL TECHNOLOGY USE BY TYPE, 2002

Table 39 SOLUTION BEAD/PARTICLE PROTEIN ARRAY DETECTION TECHNOLOGY USE BY TYPE, 2002

• SOLUTION BEAD/PARTICLE ARRAY MARKET SHARE

Table 40 SOLUTION BEAD/PARTICLE ARRAY COMPANY MARKET SHARE, 2002

• Luminex Corp.
  • Solution Bead/Particle Collaborators

Table 41 LUMINEX RESEARCH/DRUG DISCOVERY PARTNERS AND APPLICATIONS

Table 42 LUMINEX DIAGNOSTIC PARTNERS AND APPLICATIONS

Table 43 SOLUTION BEAD/PARTICLE COLLABORATIONS, BY APPLICATION AREA, 2002

• Biochip versus Bead/Particle Protein Array Study
  • Results
• Luminex Venture FDA-Approved Products
  • Luminex Venture FDA-Approved Products (Continued)

PROTEIN ARRAY APPLICATION MARKETS

Table 44 PROTEIN ARRAY APPLICATION SECTOR SALES, THROUGH 2007 ($ MILLIONS)

• RESEARCH PROTEIN ARRAY TECHNOLOGY SECTOR

Table 45 RESEARCH PROTEIN ARRAY TECHNOLOGY SALES BY CATEGORY, THROUGH 2007 ($ MILLIONS)

• Antibody Array Technology Research Market Players

Table 46 ANTIBODY PROTEIN ARRAY TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002

Figure 7 ANTIBODY PROTEIN ARRAY TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002 (%)

• Peptide Biochip Protein Array Technology Research Market Players

Table 47 PEPTIDE BIOCHIP TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002 (%)

• Protein Biochip Array Technology Research Market Players

Table 48 PROTEIN BIOCHIP ARRAY TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002 (%)

Figure 8 PROTEIN BIOCHIP ARRAY TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002 (%)

• Solution Bead/Particle Protein Array Technology Research Market Players

Table 49 SOLUTION BEAD/PARTICLE PROTEIN ARRAY TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002

• Content Specific Research Protein Array Market Players
  • Cytokines
  • Kinases
• CLINICAL PROTEIN ARRAY TECHNOLOGY

Table 50 PROTEIN ARRAY TECHNOLOGY CLINICAL MARKET SALES, THROUGH 2007 ($ MILLIONS)

• PROTEIN ARRAY CONTENT DEVELOPMENT

Table 51 SELECTED AVAILABLE PROTEIN ARRAY TARGET MARKET DATA ($ MILLIONS)

• CONTENT-SPECIFIC PROTEIN ARRAY TECHNOLOGY PLAYERS

Table 52 CONTENT-SPECIFIC PROTEIN ARRAY TECHNOLOGY PLAYERS, BY APPLICATION

• CONTENT-SPECIFIC PROTEIN ARRAY TECHNOLOGY MARKETS
  • Allergy
  • Alzheimer's Disease
  • Angiogenesis

Table 53 ANGIOGENESIS-DEPENDENT DISEASES

• Cancer
• Drugs of Abuse
• Fertility
• Immune/Autoimmune Diseases
• Obesity
• Pathogens
• Therapeutic Drugs
• Tissue Typing/Cardiac Marker
• Thyroid
• CONTENT-SPECIFIC PROTEIN ARRAY TECHNOLOGY DEVELOPERS

Table 54 CONTENT-SPECIFIC PROTEIN ARRAY TECHNOLOGY DEVELOPERS, BY APPLICATION

• SPOTTING ARRAYERS
  • NEW DEVELOPMENTS
• PROTEIN BIOCHIP ENHANCERS
• BIOINFORMATICS
  • TECHNOLOGY
  • DEVELOPMENT
  • CLINICAL DIAGNOSTIC APPLICATIONS
  • BIOINFORMATIC DATA STANDARDS

PATENTS

Table 55 PROTEIN ARRAY TECHNOLOGY PATENT FILINGS, 1989-2002

• ANTIBODY ARRAY PATENTS

Table 56 ANTIBODY ARRAY PATENTS

Table 57 ANTIBODY ARRAY PATENTS BY ASSIGNEE, 2000-2002

• PEPTIDE BIOCHIP ARRAY PATENTS

Table 58 PEPTIDE BIOCHIP ARRAY PATENTS

Table 59 PEPTIDE PATENT ARRAYS BY ASSIGNEE, 1999-2002

• PROTEIN BIOCHIP ARRAY PATENTS

Table 60 NUMBER OF NEW PROTEIN BIOCHIP ARRAY PATENTS

Table 61 PROTEIN BIOCHIP ARRAY PATENTS, 1989-2002

Table 61 (CONTINUED)

Table 61 (CONTINUED)

Table 61 (CONTINUED)

Table 62 PROTEIN BIOCHIP ARRAY PATENTS BY ASSIGNEE, 1989-2002

Table 62 (CONTINUED)

• CIPHERGEN, LUMICYTE, MAS PATENT DISPUTE
• PROTEIN SOLUTION BEAD/PARTICLE ARRAY PATENTS

Table 63 NUMBER OF NEW PROTEIN BIOCHIP ARRAY PATENTS, 1998-2002

Table 64 PROTEIN SOLUTION BEAD/PARTICLE ARRAY PATENTS

Table 64 (CONTINUED)

Table 65 PROTEIN SOLUTION BEAD/PARTICLE ARRAY PATENTS BY ASSIGNEE, 1998-2002

APPENDIX I - PROTEIN ARRAY COMPANY PROFILES

• ANTIBODY ARRAY COMPANIES
  • BD BIOSCIENCES CLONTECH
  • DOMANTIS LTD.
  • HYPROMATRIX, INC.
  • MILAGEN, INC.
  • PERKIN-ELMER LIFE SCIENCES/PACKARD BIOSCIENCE
  • PANOMICS, INC.
  • PIERCE BIOTECHNOLOGY, INC.
  • RAYBIOTECH, INC.
  • SCHLEICHER & SCHUELL BIOSCIENCE, INC.
• PROTEIN BIOCHIP ARRAY COMPANIES
  • ADVANCED ARRAY TECHNOLOGY S.A.
  • AFFIBODY AB
  • ASPIRA BIOSYSTEMS, INC.
  • AXCELL BIOSCIENCES CORP.
  • BIACORE, INC.
  • BIOCEPT, INC
  • BIOFORCE NANOSCIENCES, INC.
  • CIPHERGEN BIOSYSTEMS, INC.
  • GENOMIC SOLUTIONS, INC.
  • HTS BIOSYTEMS
  • HYBRIGENICS SA
  • LUMICYTE, INC.
  • MESO SCALE DISCOVERY
  • METRIGENIX, INC.
  • MIRAGENE, INC.
  • MOLECULAR STAGING, INC.
  • MOREWOOD MOLECULAR, INC.
  • NEXTGEN SCIENCES LTD.
  • PERKIN-ELMER LIFE SCIENCES/PACKARD BIOSCIENCE
  • PROLINX, INC.
  • PROTOMETRIX
  • PROTIVERIS INC.
  • RANDOX LABORATORIES LTD.
  • SOMALOGIC, INC.
  • SURFACE LOGIX, INC.
  • TELECHEM INTERNATIONAL, INC.
  • ZEPTOSENS AG
  • ZYOMYX, INC.
• PROTEIN BIOCHIP ARRAY ENHANCER COMPANIES
  • ADVALYTIX
  • GENICON SCIENCES CORP.
• PEPTIDE ARRAY COMPANIES
  • JERINI AG
  • PEPSCAN
  • XEOTRON CORP.
• SOLUTION BEAD ARRAY COMPANIES
  • BIOPLEX CORP. (CRYSTALPLEX CORP.)
  • LUMINEX CORP.
  • NANOPLEX TECHNOLOGIES, INC.
  • QUANTUMDOT CORP.
  • SMARTBEAD TECHNOLOGIES LTD.
  • VERITY BIOSYSTEMS
• PROTEIN ARRAY SPOTTING INSTRUMENT COMPANIES
  • DIGITALGENE BIOSCIENCES, LTD.
  • TELECHEM INTERNATIONAL
    • Telechem International (Continued)

APPENDIX II - ASSOCIATIONS

• HUMAN PROTEOME ORGANIZATION (HUPO)
• BIOPAX
• BIOLOGICAL PATHWAYS
• PLASMA PROTEOME INSTITUTE (PPI)
• PROTEOME SOCIETY

 

LIST OF TABLES

• Summary Table:
  WORLDWIDE PROTEIN ARRAY TECHNOLOGY SALES BY MARKET SEGMENT, THROUGH 2007 ($ Millions)
• Table 1 PROTEIN CAPTURE MOLECULES AND TARGETS
• Table 2 R&D SPENDING IN THE GLOBAL PHARMACEUTICAL INDUSTRY, 1980-2002 ($ MILLIONS)
• Table 3 DISTRIBUTION OF DRUG RESEARCH COSTS
• Table 4 DRUGS APPROVED BY THE FDA, 1993-2002 (# DRUGS)
• Table 5 PROTEIN ARRAY TECHNOLOGY COMPANIES AND MARKET SHARES, BY CATEGORY, 2002
• Table 6 WORLDWIDE PROTEIN ARRAY TECHNOLOGY SALES BY CATEGORY, THROUGH 2007 ($ MILLIONS)
• Table 7 WORLDWIDE DISTRIBUTION OF PROTEIN ARRAY TECHNOLOGY COMPANIES BY CATEGORY, 2002
• Table 8 COMPANIES WORLDWIDE THAT LAUNCHED PROTEIN ARRAY TECHNOLOGY PRODUCTS, BY CATEGORY, 1999-2002
• Table 9 PROTEIN ARRAY TECHNOLOGY PRODUCT LAUNCHES, BY CATEGORY, 2002 (%)
• Table 10 COMPANIES THAT LAUNCHED ANTIBODY ARRAY PRODUCTS, 1999-2002
• Table 11 WORLDWIDE ANTIBODY ARRAY TECHNOLOGY SALES, THROUGH 2007 ($ MILLIONS)
• Table 12 ANTIBODY ARRAY TECHNOLOGY PRODUCT LAUNCHES, BY COMPANY, 2000-2002
• Table 13 SUMMARY OF ANTIBODY ARRAY TECHNOLOGY FEATURES, BY COMPANY
• Table 14 ANTIBODY ARRAY SURFACE MATERIAL USE, BY TYPE, 2002
• Table 15 ANTIBODY ARRAY DETECTION METHOD USE BY TYPE, 2002
• Table 16 ANTIBODY ARRAY TECHNOLOGY COMPANY MARKET SHARE, 2002
• Table 17 APPLICATIONS/TYPES OF ANTIBODY ARRAY TECHNOLOGY, BY COMPANY
• Table 18 WORLDWIDE PEPTIDE BIOCHIP ARRAY TECHNOLOGY SALES, THROUGH 2007 ($ MILLIONS)
• Table 19 PEPTIDE ARRAY PRODUCT LAUNCHES, 1999-2002
• Table 20 PEPTIDE BIOCHIP TECHNOLOGY LAUNCHES BY COMPANY, 2000-2004
• Table 21 PEPTIDE BIOCHIP TECHNOLOGY FEATURES, BY COMPANY
• Table 22 PEPTIDE ARRAY SURFACE MATERIAL USE, BY COMPANY
• Table 23 PEPTIDE ARRAY DETECTION METHOD BY COMPANY
• Table 24 WORLDWIDE PROTEIN BIOCHIP ARRAY TECHNOLOGY SALES, THROUGH 2007 ($ MILLIONS)
• Table 25 PROTEIN BIOCHIP TECHNOLOGY COMPANIES
• Table 26 COMPANIES THAT LAUNCHED PROTEIN BIOCHIPS, 1999-2002
• Table 27 PROTEIN BIOCHIP PRODUCT LAUNCHES BY COMPANY, 1999-2002
• Table 28 PROTEIN BIOCHIP ARRAY PRODUCTS/SERVICES FEATURES BY COMPANY
• Table 29 PROTEIN BIOCHIP ARRAY TECHNOLOGY COMPANY MARKET SHARES, 2002 (%)
• Table 30 COMPANIES WITH PROTEIN BIOCHIP ARRAY TECHNOLOGY IN DEVELOPMENT
• Table 31 PROTEIN BIOCHIP ARRAY SURFACE MATERIAL USE, BY TYPE, 2002
• Table 32 PROTEIN BIOCHIP ARRAY SURFACE MATERIAL DESCRIPTION, BY COMPANY
• Table 33 PROTEIN BIOCHIP ARRAY DETECTION METHOD USE BY TYPE, 2002
• Table 34 PROTEIN BIOCHIP ARRAY DETECTION METHOD DESCRIPTION, BY COMPANY
• Table 35 SOLUTION BEAD/PARTICLE PROTEIN ARRAY TECHNOLOGY SALES, THROUGH 2007 ($ MILLIONS)
• Table 36 SOLUTION BEAD/PARTICLE PROTEIN ARRAY TECHNOLOGY COMPANIES
• Table 37 SUMMARY OF SOLUTION BEAD/PARTICLE PROTEIN ARRAY TECHNOLOGY FEATURES BY COMPANY
• Table 38 SOLUTION BEAD/PARTICLE PROTEIN ARRAY MATERIAL TECHNOLOGY USE BY TYPE, 2002
• Table 39 SOLUTION BEAD/PARTICLE PROTEIN ARRAY DETECTION TECHNOLOGY USE BY TYPE, 2002
• Table 40 SOLUTION BEAD/PARTICLE ARRAY COMPANY MARKET SHARE, 2002
• Table 41 LUMINEX RESEARCH/DRUG DISCOVERY PARTNERS AND APPLICATIONS
• Table 42 LUMINEX DIAGNOSTIC PARTNERS AND APPLICATIONS
• Table 43 SOLUTION BEAD/PARTICLE COLLABORATIONS, BY APPLICATION AREA, 2002
• Table 44 PROTEIN ARRAY APPLICATION SECTOR SALES, THROUGH 2007 ($ MILLIONS)
• Table 45 RESEARCH PROTEIN ARRAY TECHNOLOGY SALES BY CATEGORY, THROUGH 2007 ($ MILLIONS)
• Table 46 ANTIBODY PROTEIN ARRAY TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002
• Table 47 PEPTIDE BIOCHIP TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002 (%)
• Table 48 PROTEIN BIOCHIP ARRAY TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002 (%)
• Table 49 SOLUTION BEAD/PARTICLE PROTEIN ARRAY TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002 (%)
• Table 50 PROTEIN ARRAY TECHNOLOGY CLINICAL MARKET SALES, THROUGH 2007 ($ MILLIONS)
• Table 51 SELECTED AVAILABLE PROTEIN ARRAY TARGET MARKET DATA ($ MILLIONS)
• Table 52 CONTENT-SPECIFIC PROTEIN ARRAY TECHNOLOGY PLAYERS, BY APPLICATION
• Table 52 (CONTINUED)
• Table 53 ANGIOGENESIS-DEPENDENT DISEASES
• Table 54 CONTENT-SPECIFIC PROTEIN ARRAY TECHNOLOGY DEVELOPERS, BY APPLICATION
• Table 55 PROTEIN ARRAY TECHNOLOGY PATENT FILINGS, 1989-2002
• Table 56 ANTIBODY ARRAY PATENTS
• Table 57 ANTIBODY ARRAY PATENTS BY ASSIGNEE, 2000-2002
• Table 58 PEPTIDE BIOCHIP ARRAY PATENTS
• Table 59 PEPTIDE PATENT ARRAYS BY ASSIGNEE, 1999-2002
• Table 60 NUMBER OF NEW PROTEIN BIOCHIP ARRAY PATENTS
• Table 61 PROTEIN BIOCHIP ARRAY PATENTS, 1989-2002
• Table 62 PROTEIN BIOCHIP ARRAY PATENTS BY ASSIGNEE, 1989-2002
• Table 63 NUMBER OF NEW PROTEIN BIOCHIP ARRAY PATENTS, 1998-2002
• Table 64 PROTEIN SOLUTION BEAD/PARTICLE ARRAY PATENTS
• Table 65 PROTEIN SOLUTION BEAD/PARTICLE ARRAY PATENTS BY ASSIGNEE, 1998-2002  

LIST OF FIGURES

• Summary Figure:
  WORLDWIDE PROTEIN ARRAY TECHNOLOGY SALES BY MARKET SEGMENT, 2000-2007 ($ Millions)
• Figure 1 WORLDWIDE ANTIBODY ARRAY TECHNOLOGY SALES, 2000-2007 ($ MILLIONS)
• Figure 2 ANTIBODY ARRAY TECHNOLOGY COMPANY MARKET SHARE, 2002 (%)
• Figure 3 WORLDWIDE PEPTIDE BIOCHIP ARRAY TECHNOLOGY SALES, 2000-2007 ($ MILLIONS)
• Figure 4 WORLDWIDE PROTEIN BIOCHIP ARRAY TECHNOLOGY SALES, 2000-2007 ($ MILLIONS)
• Figure 5 PROTEIN BIOCHIP ARRAY TECHNOLOGY COMPANY MARKET SHARES, 2002 (%)
• Figure 6 SOLUTION BEAD/PARTICLE PROTEIN ARRAY TECHNOLOGY SALES, THROUGH 2007 ($ MILLIONS)
• Figure 7 ANTIBODY PROTEIN ARRAY TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002 (%)
• Figure 8 PROTEIN BIOCHIP ARRAY TECHNOLOGY RESEARCH MARKET SHARE BY COMPANY, 2002 (%)