HIGH TECH SEPARATION INDUSTRY REVIEW 2002

TABLE OF CONTENTS

INTRODUCTION/SUMMARY

• BCC ON-LINE SERVICES

ADSORBENTS

• PARTICLES ASSIST IN BLOOD SAFETY
• PARTICLES ASSIST IN BLOOD SAFETY (CONTINUED)
• SURFACE TREATMENT UPS INTAKE RATE
• HEAT RESISTANCE IMPROVED IN PSA
• HEAT RESISTANCE IMPROVED IN PSA (CONTINUED)

ADSORBTION

• METAL COMPOUNDS REMOVE ALKENES

ADSORPTION

• PRESSURE EQUALIZED IN FOUR STEPS
• ZEOLITES CAPTURE SF6 FROM EXHAUST GASES
• POLYACTAM POWDER REMOVES MICROBES
• PALLADIUM RECOVERY SIMPLIFIED

ADVANCED FILTRATION

• OZONE DOES NOT AFFECT HF MODULE
• SYSTEM PROVIDES ULTRAPURE WATER
• MONITOR PROVIDES REAL-TIME INFO
• MONITOR PROVIDES REAL-TIME INFO (CONTINUED)
• FUNNEL STREAMLINES SAMPLING, TESTING
• CAPSULE HANDLES SMALL BATCHES
• S-LAYERS OFFER CONTROL, ORGANIZATION
• SWITCH SENSOR REMOVES ERROR
• FLUSH EXTENDS MEMBRANE LIFE
• FOIL BOND RESISTS SOLVENT BREAKDOWN
• TFF SYSTEM MINIMIZES SHEAR, EASES CLEANING
• MANIFOLDS FILTERS STOP MANUFACTURING TAINT
• FILTER RESISTS PULSED PRESSURE
• SMART MEMBRANE PURIFIES DRUGS
• MEMBRANES CUT TREATMENT COST
• THIN-WALLED FILTER LOWERS COST
• MEMBRANE PURIFIER REMOVES TRACE METALS
• ANTIBODIES GUIDE CHIRAL SEPARATIONS
• CERAMIC MICROFIBERS READILY ASSEMBLED
• LOW-COST EMERGENCY SOLUTION OFFERED
• LOW-COST EMERGENCY SOLUTION OFFERED (CONTINUED)
• TMAA DOUBLES BACTERIA CAPTURE
• HOUSING STREAMLINES BIOPROCESSING
• BARRIERS ENHANCE CANDLE HOLDERS
• BIOPROCESSING OF DRUG THERAPIES SPEEDED UP
• MF UNIT AVOIDS CROSS-CONTAMINATION
• BALSTON COALESCER LINE UPDATED
• POLLUTANTS REMOVED AT 90 NM LEVEL
• MIXED MEDIA UP THROUGHPUT
• PHASE TRANSITION AFFECTS PERFORMANCE
• UF MARKET TO CROSS $725 MILLION BY 2007 IN THE U.S.
• UF MARKET TO CROSS $725 MILLION BY 2007 IN THE U.S. (CONTINUED)
• TABLE 1 U.S. MARKET FOR ULTRAFILTRATION, THROUGH 2007 ($ MILLIONS)

ARRAYS

• SYSTEMS SPEED GENETIC RESEARCH
• ENZYME ASSAYS LABELED IN-LINE

BIOSENSORS

• CELL-BASED UNITS DETECT ANTAGONISTS
• U.S. MARKET FOR BIOSENSORS AND BIOELECTRONICS TO CROSS $1.81 BILLION BY 2006
• TABLE 2 U.S. MARKET FOR BIOSNESORS AND BIOELECTRONICS, THROUGH 2006 ($ MILLIONS)
• FIGURE 1 U.S. MARKET FOR BIOSNESORS AND BIOELECTRONICS, 2001 AND 2006 ($ MILLIONS)

CENTRIFUGATION

• STANDSTILL HEATING ENHANCES LAB UNIT
• DUAL OPERATIONS CUT RUNS BY 70%
• ATTACHMENT HELPS CELL PURIFICATION
• FRUSTO-CONICAL DESIGN WORKS WITHOUT WICK
• FRUSTO-CONICAL DESIGN WORKS WITHOUT WICK (CONTINUED)
• SPINNING LAB ON A DISC OFFERS BENEFITS
• SPINDLE LESSENS ROTOR VIBRATION
• ROTOR WITH FLOW BYPASS
• BECKMAN COULTER LAUNCHES ULTRACENTRIFUGE

CHROMATOGRAPHY

• ELUENT SUPPRESSOR KEEPS ITS COOL
• LYSOZYME DIMER WITHOUT TOXICITY
• PROTEIN SCREEN FINDS SINGLE BASE CHANGE
• UNITS SAVE CRITICAL PROCESSING TIME
• LINEAR PLOT TESTS ROBUSTNESS
• DUAL PATH FLOW CELL DETECTS ABSORBANCE
• CELL THERAPEUTICS TARGETS LIPIDS
• WASH STEP IMPROVES PROTEIN PURIFICATION
• COLUMN ISOLATES PACLITAXEL CLEANLY
• HEAT TREATMENT HELPS CLONE GENE
• CONDUCTIVITY CHANGE RESOLVES POLYPEPTIDE
• UT ISOLATES, IDENTIFIES TOXINS
• CELLULOSE BEADS REMOVE ENDOTOXINS
• HATCHERIES YIELD SALMON EGG ZONASES
• CHIRAL SYNTHESIS BEATS SOLUBILITY
• 2-D ANALYSIS ALLOWS PREP COMBO SCRUTINY
• ACTIVATED CARBON STRENGTHENS PAPER
• AUTOMATION, CALIBRATION BOOSTS SYSTEM SPEED
• PHASE IMPROVES MIXTURE ANALYSIS
• MICROPASSAGES REDUCE FRIT PACK PRESSURE
• DEGRADED HEPARANASE FLAGS CANCER
• DEGRADED HEPARANASE FLAGS CANCER (CONTINUED)
• SYSTEM SWITCHES BETWEEN LIQUID, GAS
• IN SITU EXTRACTION HARVESTS FATTY ACIDS
• COOLING COIL CONTROLS INJECTOR TEMPERATURE
• PACKING KEEPS DISPERSION LOW
• COLUMN CONTROL IMPROVES ANALYSIS
• LIQUID SYSTEM SPEEDS PROTEIN SEPARATION
• MEMBRANE UNITS BOOST FLOW RATES 100-FOLD
• SIMULTANEOUS SHIFT MORE ECONOMICAL
• DOUBLE COLUMNS DETECT PLATINUM
• MULTIVALENT CATION LACK GIVES GREATER DEFINITION
• COLUMN COATINGS NIX ADSORPTION PROBLEMS
• SYSTEM EXTRACTS, PURIFIES L-ARABINOSE
• READY-MADE STANDARDS VALIDATE DHPLC OPERATION
• ELECTRONIC "TONGUE" LICKS EFFLUENT
• COMPUTER CONTROLS TEN CHANNELS
• MULTIPLEXED METHOD SAVES STEPS
• METHOD PURIFIES ADENOVIRUS
• POLYMER MATRICES ADD SOLUBILITY, SELECTIVITY
• INTEGRATED SYSTEM HAS HIGH SENSITIVITY
• MEMBRANE CHROMATOGRAPHY STACKED ADSORBERS FAST, ECONOMICAL
• DISPOSABLE CARTRIDGES BOOST YIELD, CUT COST
• TRACES SENSITIVITY SCANS RAPIDLY
• LIQUIDITY REDUCES SAMPLING TIME
• 2-D METHOD ENHANCES RESOLUTION
• PORES SPEED LARGE MOLECULE PURIFICATION
• PROCESS IDENTIFIES ANTIOXIDANTS
• ESSENTIAL ELEMENTS EXTRACTED FROM HEMP
• UOP IMPROVES LOADING EFFICIENCY
• COLUMNS SPEED MASS TRANSFER
• AGILENT CHARACTERIZES COMPLEX FORMULATIONS
• KIONIX SPEEDS UP EVALUATION
• PROCESS IMPROVES SAMPLE RECOVERY TIME
• CONSEJO SUPERIOR COUPLES LC AND GC
• AGILENT IMPROVES THROUGHPUT
• LC PACKING IMPROVES MICRO COLUMN SWITCHING
• MICROMASS PROFILES DRUGS
• VALVES YIELD HIGHER SEPARATION PERFORMANCE
• PERKINELMER LAUNCHES CLARUS LINE
• EZ-FLASH MONITORS ESSENTIAL OILS
• KTA-TATOR INSPECTS COATINGS
• GENENTECH ISOLATES NGFS
• INJECTION METHOD IMPROVES SAFETY
• INTEGRATED SYSTEM SPEEDS ANALYSIS
• SYMYX SYSTEM IDENTIFIES POLYMERS
• METHOD SUPPRESSES ELUENT SOLUTIONS
• SOFTWARE EXPANDS FX PLATFORM
• DIONEX UNVEILS FOUR PUMPS
• HPLC MEASURES ANTIRETROVIRAL DRUGS
• DETECTOR SIMPLIFIES ANALYSES
• AGILENT DETECTS PAHS IN WATER
• PURIFICATION PROCESS YIELDS IGIV-C PRODUCT
• IEC METHOD PURIFIES PEPTIDE
• GERSTEL ELIMINATES WATER FROM SAMPLES
• PORT ALLOWS EASY PACKING
• ALLTECH PROCESS REMOVES GAS
• CARTRIDGE OFFERS CONVENIENCE
• TURBOFLOW GAINS ACCEPTANCE
• SYMYX DETECTS AND CHARACTERIZES
• TECAN LAUNCHES PROTEOMICS LINE
• ARGONAUT SOFTWARE SIMPLIFIES FLASHMASTER
• VARIAN SPEEDS BIOANALYSIS
• CAMBRIDGE ELECTRIFIES FOR LESS
• DEGASSER HANDLES ALL COMERS
• APPLIED BIOSYSTEMS GETS SENSITIVE
• CLARUS SYSTEMS OFFERS LANGUAGE OPTIONS
• KIONIX ELECTROSPRAY SPEEDS ANALYSIS
• SYSTEM USES FEWER COMPONENTS
• AGILENT COLUMNS REDUCE ADSORPTION
• SYMYX ANALYZES NONBIOLOGICAL POLYMERS
• SANDIA GOES WITH THE FLOW
• AGILENT COMPARES TOXIC COMPOUNDS
• PROMETIC ADSORBENTS PURIFY DNA
• ESA DETECTS AT ZEPTOMOLE LEVELS
• GERSTEL SIMPLIFIES SAMPLE PREPARATION
• AMERSHAM PROVIDES HIGH RESOLUTION
• ISCO SOFTWARE OFFERS CONVENIENCE
• FLASH COLUMN SCALES UP
• AGILENT SPEEDS ANALYSIS
• PALL DELIVERS HIGH FLOW RATES
• ESA ANALYTICAL AIDS TUMOR DIAGNOSIS
• MILLIPORE DEVELOPS PROTEIN PURIFICATION
• COLUMNS DETECT LOW CONCENTRATIONS
• SHISEIDO PACKS POLYMERS
• AGILENT ANALYZES ALKALOIDS
• U.S. EXPENDITURES FOR REAGENTS USED IN CHROMATOGRAPHY ARE EXPECTED TO CROSS $2.7 BILLION IN 2007
• TABLE 3 U.S. EXPENDITURE FOR THE REAGENTS USED IN DIFFERENT CHROMATOGRAPHS, THROUGH 2007 ($ MILLIONS)
• FIGURE 2 U.S. EXPENDITURE FOR THE REAGENTS USED IN DIFFERENT CHROMATOGRAPHS, 2000, 2001, 2002 AND 2007 ($ MILLIONS)

DETECTION

• UC SNIFFS OUT WEAPONS MAKERS
• BIO-RAD DETECTS ALCOHOL CONSUMPTION

DISTILLATION

• SELECTIVE SOLVENT USED AS EXTRACTANT

ELECTROPHORESIS

• ELECTOPHORETIC TAG DETECTS SNPS FOR LESS
• DENATURATION PRINTS MORE SENSITIVE
• CHAIN REACTION SPEEDS DETECTION
• HYDROPHOBIC PLASTICS FORM CAPILLARIES
• CONDUCTIVE TRAY NIXES INDIVIDUAL INSERTION
• LASER-INDUCED METHOD IMPROVES RESOLUTION
• TEN BLOTS FROM SINGLE SAMPLE
• TEN BLOTS FROM SINGLE SAMPLE (CONTINUED)
• UC DETECTS ENZYME ACTIVITY
• UOP IMPROVES CAPILLARY ASSEMBLY
• BECKMAN OFFERS FLEXIBLE ANALYSIS
• BUFFER IS KEY TO YEAR SHELF LIFE
• AGENTS SPEED CHIRAL PREPS
• TOOL CUTS MULTIPLE SAMPLES
• LASERS ENHANCE ISOMER DETECTION
• POLYMER SERIES CUTS WALL INTERACTIONS
• PARALLEL ZONE HANDLES BUFFERS BETTER
• ROBOT AUTOMATES PROTEIN PICKING
• CASSETTE DESIGN CUTS BUFFERING LABOR
• PRE-POLYMERIZED GEL COATS CAPILLARY INTERNALLY
• MICROFABRICATION ALLOWS SIMULTANEOUS DETECTION
• PLATFORM PERMITS GEL MULTIPLEXING
• DUAL CAROUSELS PREVENT CROSS-CONTAMINATION
• SPACERS PROTECT FROM PRESSURE
• 2D AUTOMATES LARGE DATA SETS
• CAPILLARY TEMPERATURE OPTIMIZES CONDITIONS
• DNA CASSETTE CUTS CONTAMINATION
• TUBE STRUCTURE MORE PRACTICAL
• CASSETTE WORKS ON PRE-CAST GELS
• INTEGRATED UNIT CHECKS MULTIPLICITY
• PROTEOMICS ANALYZES ENDOPLASMIC RETICULUM
• INVITROGEN LAUNCHES ZOOM PROTEOMICS
• DEVICE IMPROVES SAMPLE LOADING
• EASY TRANSITIONS DURING RUNS
• PRECAST PAGER GELS SUPERIOR FOR PROTEINS
• METHOD REDUCES STAINING TIME
• INTERCELL AG IDENTIFIES ANTIGENS
• TEST IDENTIFIES PESTICIDES RESISTANCE
• METHOD STREAMLINES COMPLEX SCREENING
• KIT IMPROVES RESOLUTION
• AGILENT SIMPLIFIES CONDUCTIVITY DETECTION
• NONLINEAR IMAGE ANALYSIS SOFTWARE
• SYSTEM ALLOWS CONTINUOUS OPERATION
• BIO-RAD IMPROVES EFFICIENCY
• SHIMADZU COMBINES SPEED AND RESOLUTION
• STONY BROOK CHEAPENS SEQUENCING
• COSMO SIMPLIFIES PROTEIN ANALYSIS
• SYMYX SYSTEM REDUCES NOISE
• PROMEGA POLYMERASE SAVES TIME
• LARGE SCALE IDENTIFIES PROTEINS
• OXFORD CHARACTERIZES BIOMOLECULES
• CORNELL MINIATURIZES ION SPRAYER
• SANDIA METHOD DETECTS EXPLOSIVES
• SANDIA METHOD DETECTS EXPLOSIVES (CONTINUED)

EXTRACTION

• KIT RAPIDLY ISOLATES DNA
• VARIAN SIMPLIFIES POLAR COMPOUNDS
• BUCCAL KITS SPEED PCR ASSAYS
• ARRAY PROFILES MULTIPLE PROTEINS
• ARRAY PROFILES MULTIPLE PROTEINS (CONTINUED)

HYBRID TECHNIQUES

• EXTRACTION THAT�fS MORE EFFICIENT
• SOLVENT SUCKS MORE HIGH FROM CANNABIS
• AGILENT DATABASES SIMPLIFY ANALYSIS
• SCREENING ASSAYS FOR DIOXINS
• WATERS ADVANCES PROTEIN ANALYSIS
• PERKINELMER PRODUCTS IMPROVES PRODUCTION
• PERKINELMER PRODUCTS IMPROVES PRODUCTION (CONTINUED)

INDUSTRY NEWS

• SPECTRX SETTLES WITH ALTEA
• NASDAQ-100 ADDS INVITROGEN
• ABBOTT PLANT INSPECTION CONTINUES
• O.I. CORP. GETS $2-MILLION ORDER
• SPECTRX BUYS INSULIN DELIVERY COMPANY
• LEAK DETECTOR CUTS FALSE NEGATIVES
• ILLUMINA TRIPLES OLIGO CAPACITY
• WATERS FORMING THREE UNITS
• BECKMAN COULTER SIGNS HOSPITAL PACTS
• OSMONICS ALTERS SAFETY-KLEEN DEAL
• PERKINELMER SELLS DETECTION SYSTEMS
• BIOCOMPATIBLES MUM OVER ABBOTT DEAL
• ORCHID, BECKMAN INK LICENSING AGREEMENT
• SPECTRX BUYS INSULIN DELIVERY COMPANY
• PE AND MILLIPORE TO MARKET PREP SOLUTIONS
• GRADIPORE, AVENTIS IN RESEARCH DEAL
• VARIAN WILL ACQUIRE ANSYS TECHNOLOGIES
• PALL, U.S.FILTER SIGN ACQUISITION DEAL
• AMERSHAM ACQUIRES AG, INNOVASEP
• MCDG, SPECTRX SETTLE LITIGATION
• ROHM & HAAS TO CUT MORE JOBS
• DIGENE FILES TO SELL SHARES
• ILLUMINA LICENSES BEADARRAY PATENTS
• VARIAN FINALIZES ANSYS ACQUISITION
• WAKO TO MARKET 20/20�fS �eFILM FOR LIFE�f
• GRADIPORE, BIOMIRA TO PURIFY PROTEINS
• HMSR, POINT COMPLETE MERGER
• TEAM FOR MAD COW STUDY
• AMERSHAM EXPANDS THROUGH COLLABORATION
• CIPHERGEN, BECKMAN TO COMBINE SYSTEMS
• ILLUMINA RECEIVES $1.2 MILLION GRANT
• BIO-RAD, IMMUCOR IN DISTRIBUTION PACT
• PKI, NEXTGEN SCIENCES ANNOUNCE PARTNERSHIP
• PALL ABSORBS USF DIVISION
• ABBOTT PLANS TO BUY HOKURIKU SEIYAKU
• ILLUMINA SIGNS GENOTYPING AGREEMENT
• ILLUMINA TEAMS WITH PLACER, LLC
• BIO-RAD ACQUIRES QUANTASE, LTD.
• PALL EXPANDS LI PRESENCE
• NANOGEN, GENETIC TECH SIGN DNA ANALYSIS DEAL
• ZIRCHROM GARNERS RESEARCH AWARD
• JUDGE UPHOLDS WATERS DECISION
• BECKMAN JOINS WITH JAPAN�fS MBL
• ROHM & HAAS INCREASES R&D
• DIONEX INVESTMENT IN PHARMASEQ
• CANADA INVESTS IN PROTEOMICS
• O.I. CORP. MONITORS WARFARE AGENTS
• ILLUMINA WINS SBIR GRANT
• Q TRAP LAUNCHED ON CANADIAN MARKET
• NANOGEN, BIO-RAD SIGN HH LICENSE
• NANOGEN WORKS WITH NASA
• PERKINELMER NAMED IN SECURITIES SUIT
• ILLUMINA DEPLOYS SNP MARKERS
• DNA TEST FIGHTS FRAUD
• AGILENT SETTLES CIVIL FRAUD SUIT
• SEPRACOR RESEARCH CHIEF RESIGNS
• NOVAGEN PURIFIES WITH PERKINELMER
• ILLUMINA SIGNS GENOTYPING DEAL
• NANOGEN GETS FAVORABLE RULING
• NANOGEN GETS FAVORABLE RULING (CONTINUED)
• CLASS ACTION SUIT AGAINST PERKINELMER
• AMERSHAM INCREASES EBA CAPABILITIES
• PALL DETECTS POTENTIALLY FATAL BACTERIA IN BLOOD
• ILLUMINA, UNIVERSITY OF CAMBRIDGE JOIN FORCES
• VELQUEST PARTNERS WITH WATERS
• NANOGEN SETTLES COMBIMATRIX SUIT
• ABBOTT PAYS SPECTRX FOR MILESTONE
• EPROGEN SIGNS OEM LICENSE AGREEMENT
• ILLUMINA GENOTYPES FOR GLAXOSMITHKLINE
• BIONOMICS, NANOGEN SIGN DIAGNOSTIC DEAL
• ENZO BIOCHEM SUES PERKINELMER
• COURT FINDS CUNO INFRINGED PATENTS
• GE POWER SYSTEMS TO ACQUIRE OSMONICS
• FDA CLEARS PALL�fS LEUKOCYTE FILTER
• PERKINELMER COMBINES BUSINESS UNITS
• BECKMAN COULTER RENEWS MAGNET DEAL
• INFORMAX ACQUIRED BY INVITROGEN
• BIO-RAD BREAKS NEW GROUND
• USDA APPROVES BIO-RAD DEER DISEASE KIT
• NIH GRANT FUNDS ALZHEIMER�fS STUDY
• OLIGONUCLEOTIDES USED IN STUDY
• BRIEFLY NOTED
• OSMONICS TO CLOSE SYRACUSE, NY, PLANT
• WHATMAN HEMASURE SIGNS PURCHASE AGREEMENT WITH BLOOD CENTERS OF AMERICA
• BIO-RAD LABORATORIES TO AMEND ITS CERTIFICATE OF INCORPORATION
• BIO-RAD LABORATORIESVP/CFO RESIGNS
• ABBOTT REPORTS 4Q PROFITS FALL
• BECKMAN COULTER PROFITS RISE
• DIONEX POSTS LOWER Q2 PROFITS
• PERKINELMER SHOWS Q4 LOSS
• VARIAN EARNINGS UP 17%
• WATERS 4Q SALES UP
• VARIAN PROMOTES O�fDONOGHUE
• BIO-RAD BOARD OKS 2-FOR-1 SPLIT
• INVITROGEN RELEASES 2001 RESULTS
• O.I. REPORTS RECORD EARNINGS
• OSMONICS 4Q INCOME GROWS 20%
• PALL REPORTS 2Q RESULTS
• SPECTRX REPORTS NET LOSS
• GRADIPORE OPENS U.S. OFFICE, LAB
• AMERSHAM BIOSCIENCES APPOINTS SENIOR VP OF GENOMICS
• NANOGEN MAKES MANAGEMENT CHANGES
• PERKINELMER APPOINTS COOK VP OF LIFE SCIENCES R&D
• VARIAN ELECTS CEO LAUER BOARD CHAIRMAN
• APPLIED BIOSYSTEMS WINS A RULING IN ITS LAWSUIT AGAINST WATERS CORP.
• ISCO FISCAL SECOND-QUARTER EARNINGS FALL
• INVITROGEN STOCK TAKES A DIVE
• BECKMAN COULTER�fS PRESIDENT OF THE CLINICAL DIAGNOSTICS DIVISION TO RETIRE
• ABBOTT LABORATORIES POSTS FIRST-QUARTER PROFIT
• BIO-RAD LABORATORIES REPORTS RISE IN REVENUES
• DIONEX ANNOUNCES DIP IN 3RD QTR. REVENUES AND EARNINGS
• ILLUMINA REPORTS NET LOSS IN FIRST QUARTER
• PERKINELMER ANNOUNCES DIP IN FIRST QUARTER 2002 REVENUE
• VARIAN�fS FISCAL SECOND-QUARTER PROFITS RISE
• WATERS CORP. FIRST-QUARTER 2002 SALES INCREASED
• MILLIPORE CORP. FIRST QUARTER EARNINGS GO UP
• INVITROGEN TO CLOSE HUNTSVILLE, AL PLANT
• ISCO REPORTS NET INCOME RISE FOR THE FISCAL THIRD QUARTER
• PALL CORP. THIRD QUARTER SALES AND EARNINGS
• POINT THERAPEUTICS REPORTS FIRST QUARTER NET LOSS
• MILLIPORE DEDICATES NEW BIOPHARMACEUTICAL TECH CENTER
• NANOGEN APPOINT SENIOR VICE-PRESIDENT OF OPERATIONS
• ROHM AND HAAS CO. REPORTS SHARP RISE IN SECOND-QUARTER EARNINGS
• WATERS CORP. TO REPURCHASE ITS OUTSTANDING COMMON SHARES
• BECKMAN COULTER HIRES CLINICAL DIAGNOSTICS DIVISION PRESIDENT
• INVITROGEN NAMES NEW CHIEF FINANCIAL OFFICER
• DIONEX NAMED NEW PRESIDENT AND CHIEF EXECUTIVE OFFICER
• BECKMAN COULTER SECOND-QUARTER 2002 PROFIT RISES
• DIONEX FOURTH QUARTER REVENUES AND EARNINGS INCREASE
• ILLUMINA ANNOUNCES SECOND QUARTER LOSS
• INVITROGEN ANNOUNCE SLIGHT RISE IN SECOND QUARTER REVENUES
• NANOGEN SEES JUMP IN SECOND QUARTER PRODUCT REVENUES
• OSMONICS REPORTS INCREASE IN SECOND QUARTER SALES
• PERKINELMER SECOND QUARTER REVENUE RISES
• POINT THERAPEUTICS REPORTS SECOND QUARTER NET LOSS
• ROHM AND HAAS CO. REPORT LOWER SECOND-QUARTER PROFIT
• SPECTRX REVENUE INCREASES
• VARIAN�fS LIFE SCIENCE AND CHEMICAL ANALYSIS PRODUCTS HELP EARNINGS RISE
• WATERS CORP. REPORTS INCREASE IN SECOND QUARTER SALES
• PERKINELMER MAKES MANAGEMENT TEAM APPOINTMENTS
• BECKMAN COULTER NAMES VICE PRESIDENT, MANUFACTURING, AND INTEGRATED SUPPLY CHAIN SERVICES
• PALL CORP. CLOSED SALE OF UNSECURED SENIOR NOTES
• BIO-RAD LABORATORIES ANNOUNCED SECOND-QUARTER FINANCIAL RESULTS
• O.I. CORP. ANNOUNCED RESULTS FOR THE FIRST HALF OF 2002
• ISCO REPORTS NET INCOME FOR THE FISCAL FOURTH QUARTER
• PALL CORP. REPORTS FOURTH QUARTER SALES AND EARNINGS RESULTS
• ROHM AND HAAS CO. EXPECTS ITS EARNINGS TO FALL SHORT OF EXPECTATIONS
• VARIAN APPOINTS VP AND GM OF THE NMR SYSTEMS BUSINESS
• BECKMAN COULTER THIRD QUARTER RESULTS ARE IN LINE
• DIONEX CORP. REPORTS FIRST QUARTER REVENUES AND EARNINGS
• ILLUMINA REPORTS THIRD QUARTER NET LOSS
• INVITROGEN CORP. THIRD QUARTER REVENUES ARE UP
• ROHM AND HAAS CO. REPORTS THIRD QUARTER NET EARNINGS
• OSMONICS INC. REPORTS THIRD QUARTER SALES
• SPECTRX SEES RISE IN REVENUE
• PERKINELMER REVENUE FROM CONTINUING OPERATIONS IS UP 5%
• VARIAN SEES RECORD FOURTH QUARTER REVENUES AND PROFITS
• WATERS CORP. REPORTS INCREASE IN THIRD QUARTER SALES
• ROHM AND HAAS REACHES SETTLEMENT WITH LLOYD�fS LONDON UNDERWRITERS
• BIO-RAD LABORATORIES ANNOUNCES THIRD QUARTER FINANCIAL RESULTS
• NANOGEN REPORTS TOTAL REVENUES FOR THE THIRD QUARTER
• O.I. CORP. REVENUE WAS UP 14%
• POINT THERAPEUTICS REPORTS THIRD QUARTER NET LOSS
• WATERS CORP. REPORTS INCREASE IN THIRD QUARTER SALES
• PERKINELMER TO RAISE MILLION
• AGILENT TECHNOLOGIES NAMES CHAIRMAN
• CHAIRMAN EMERITUS AND CURRENT DIRECTOR OF ALLERGAN RETIRES
• NANOGEN NAMES PRESIDENT AND COO
• VARIAN NAMES PRESIDENT AND COO

INDUSTRY OUTLOOK

• YEAR FEATURES MERGERS, LAWSUITS
• YEAR FEATURES MERGERS, LAWSUITS (CONTINUED)

INSTRUMENTATION

• CHECKBOX CONTROLS ACCURACY, PRECISION

ION EXCHANGE

• PROCESS CLEARS WASTEWATER COPPER

LAB-ON-A-CHIP

• LASER TRANSFERS CELL, PROTEIN PATTERNS
• PROTOCOL VALIDATES INTERNAL MUTATION
• CHANNEL WIDENS MICROFLUIDIC FUNCTIONS
• CHANNEL WIDENS MICROFLUIDIC FUNCTIONS (CONTINUED)
• PUMP NIXES SAMPLE BIAS
• DIRECT MANIPULATION BOOSTS SENSITIVITY
• SPECIFIC REAGENT TAGS GENE MUTATION
• NANOGEN CREATES CF REAGENTS
• PERKINELMER SPEEDS RNA LABELING
• AGILENT, CALIPER OFFER CELL FLUORESCENCE KIT
• TARGET CELLS IMMOBILIZED
• TARGET CELLS IMMOBILIZED (CONTINUED)

MAGNETIC SEPARATION

• BIOTIN BINDING UPS EFFICIENCY, SPEED

MEDIA

• ABSORBING POLYMER ENHANCES PRECISION
• CRYSTALS MAKE GLYCOPROTEIN STABLE
• NONPOLAR SURFACES WORK WITH MIPC
• PLUGS SIMPLIFY PEPTIDE SYNTHESIS
• COLORED BEADS ENHANCE VISIBILITY
• SUPERCRITICAL BACKWASH REMOVES PERCHLORATE
• HOMOGENEOUS ASSAY IMPROVES SCREENING
• AGILENT OFFERS KITS FOR GENE RESEARCH
• PERKINELMER LAUNCHES MICROARRAY PLATFORM
• PERKINELMER LAUNCHES MICROARRAY PLATFORM (CONTINUED)

MONITORS

• DUAL DETECTION APPROACH CLARIFIES MASS BALANCES
• REFRACTIVE INDEX MONITORS BITTER END
• REFRACTIVE INDEX MONITORS BITTER END (CONTINUED)

NOVEL TECHNIQUES

• SYSTEM IDENTIFIES SAMPLE�fS GENOTYPE
• DAIICHI MEASURES LDL CHOLESTEROLS
• ADDUCT YIELDS PYRUVIC ACIDS
• BIO-RAD AUTOMATES BSE TESTING
• LIVING CELLS GIVE MULTI-LITER PICTURE
• CHEMISTRY STABILIZES PROBE ARRAYS
• DNA EXTRACTED FROM DRIED SPECIMEN
• PATTERNED LASER IMPROVES WAFER FAB
• CHEM KITS ENHANCE SLIDE TECHNOLOGY
• CHEM KITS ENHANCE SLIDE TECHNOLOGY (CONTINUED)
• ENTROPIC FORCE OFFERS BETTER RESOLUTION
• OPH ISOLATED FROM SARIN GAS
• TECAN PLANS WORKCELL ADDITIONS
• PERKINELMER ANALYZES 10 TIMES FASTER
• TWEAKING PH AIDS HALOGEN REMOVAL
• ACTIVITY LEVEL OF ENZYME DOUBLED
• ACTIVITY LEVEL OF ENZYME DOUBLED (CONTINUED)

REAGENTS

• CROSS-PLATFORM CONTROL CAPABILITY POSSIBLE
• PERKINELMER UNVEILS REAGENT PLATFORMS
• UP TO 95% OF STEM CELLS ISOLATED
• BECKMAN COULTER MEETS MILESTONE
• PERKINELMER GETS SCREENING APPROVAL
• PERKINELMER GETS SCREENING APPROVAL (CONTINUED)

SEQUENCING

• VACUUMING ALLOWS DIRECT INJECTION
• TOOL CUTS SAMPLE PREP TIME IN HALF
• PARALLEL METHODS GENERATE INFO

SOFTWARE

• PROGRAMMING TAMES MEASUREMENT LOGJAM
• DATA ADAPTS TO WORKFLOW
• SYSTEM LINKS MANAGEMENT, DATA
• VARIAN ASSISTS VISTA-PRO USERS
• UPDATE WORKS ON LARGE GENOTYPING STUDIES
• LIMS IMPROVES FUNCTIONALITY
• LIMS IMPROVES FUNCTIONALITY (CONTINUED)

SOLID-PHASE EXTRACTION

• KIT RAPIDLY ISOLATES DNA

SOLVENT EXTRACTION

• MICROWAVE BOOSTS PRECISION, SAFETY

MASS SPECTROMETRY

• FACILITY GENERATES NITROGEN ON-SITE
• ESI/MALDI SWITCH MADE IN LESS THAN 1 MIN
• ESI/MALDI SWITCH MADE IN LESS THAN 1 MIN (CONTINUED)
• NANO SPECTRA EMITTED SIMULTANEOUSLY
• SOFTWARE PERFORMS MULTIPLE OPERATIONS
• LNA-MODIFIED PROBES ENHANCE PROPERTIES
• HYBRIDIZATION STATION PROCESSES 48 SLIDES
• ISOLATING STAGE DRIVES UNIT
• CANDIDATE LIGANDS IDENTIFIED AND RANKED
• TOOL DETECTS EARLY CANCERS
• PNNL OFFERS SPEEDY FTICR
• SULFAMETHOXAZOLE DETERMINED EASILY
• SULFAMETHOXAZOLE DETERMINED EASILY (CONTINUED)

MASS SPECTROSCOPY

• TECHNIQUE COMPARES SIMILAR SAMPLES
• VARIAN SPECTRAA-DUO 2XS ATOMIC ABSORPTION
• PULSED ION SOURCE MIMICS CONTINUOUS
• ION TRAP FASTER, MORE FACILE
• SPECTRA PROCESSED IN NATIVE FORMATS
• DEVICE DELIVERS MULTIPLE STREAMS
• SOFTWARE SETS NEW STANDARDS
• CLEARER COATING GIVES EMITTER STABILITY
• INSTRUMENT, KIT REPLACE COSTLIER MS OPTIONS
• VARIANTS DETECTED FROM SINGLE SAMPLE
• ON-SITE PORTABLE CARBON ANALYZER
• ON-SITE PORTABLE CARBON ANALYZER (CONTINUED)
• IONS DETECTED IN A WIDE RANGE OF VALUES
• SCREENING FOR MACULAR BLINDING
• MICROMASS ROLLS OUT NEW PRODUCTS
• ADVION AUTOMATES NANOELECTROSPRAY
• ADVION AUTOMATES NANOELECTROSPRAY (CONTINUED)

SUPERCRITICAL FLUIDS

• TANGENTIAL METHOD TREATS HEAVY FLUIDS
• CO2/WATER REMEDIATES METAL CONTAMINANTS
• SINGLE CHANNEL PROTOTYPE READIED
• SINGLE CHANNEL PROTOTYPE READIED (CONTINUED)

SYNTHESIS

• ARGONAUT INTRODUCES COMPACT SYNTHESIZER

 

LIST OF TABLES

TABLE 1 U.S. MARKET FOR ULTRAFILTRATION, THROUGH 2007 ($ MILLIONS)

TABLE 2 U.S. MARKET FOR BIOSNESORS AND BIOELECTRONICS, THROUGH 2006 ($ MILLIONS)

TABLE 3 U.S. EXPENDITURE FOR THE REAGENTS USED IN DIFFERENT CHROMATOGRAPHS, THROUGH 2007 ($ MILLIONS)

 

LIST OF FIGURES

FIGURE 1 U.S. MARKET FOR BIOSNESORS AND BIOELECTRONICS, 2001 AND 2006 ($ MILLIONS)

FIGURE 2 U.S. EXPENDITURE FOR THE REAGENTS USED IN DIFFERENT CHROMATOGRAPHS, 2000, 2001, 2002 AND 2007 ($ MILLIONS)