Nanostructured Materials for the Biomedical, Pharmaceutical, & Cosmetic Markets

Table of Contents

• Nanostructured Materials for the Biomedical, Pharmaceutical, & Cosmetic Markets
• Chapter 1 - EXECUTIVE SUMMARY
  • Summary Table: TOTAL WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL AND COSMETIC APPLICATIONS, THROUGH 2012 ($ MILLIONS)
  • Summary Figure: TOTAL WORLD MARKET SHARE PROJECTIONS FOR BIOMEDICAL, PHARMACEUTICAL AND COSMETIC APPLICATIONS OF NANOPARTICLES, 2006-2012 (%)
• Chapter 2 - OVERVIEW
  • TERMINOLOGY
  • PRODUCTS AND PROPERTIES
• Table 1 SUMMARY OF PROPERTY CHANGES AT THE NANOCRYSTALLINE-SIZE SCALE
  • CATALYTIC
  • ELECTRICAL
  • MAGNETIC
    • Magnetic (Continued)
  • MECHANICAL
  • OPTICAL AND ELECTRONIC
• HISTORICAL BACKGROUND
  • HISTORICAL BACKGROUND (CONTINUED)
• Figure 1 TIMELINE OF INDUSTRY EVENTS, 1920-2000
• Chapter 3 - NANOPARTICLE TECHNOLOGIES
  • PARTICLE PRODUCTION
    • TECHNOLOGIES FOR PRODUCING INORGANIC NANOPARTICLES
  • Table 2 CLASSES OF INORGANIC NANOPARTICLE PRODUCTION METHODS
• Table 3 PARTICLE PRODUCTION TECHNOLOGIES AND COMPANIES USING THEM
• Table 3 (CONTINUED)
  • Gas-Phase Processing
    • Gas Condensation with Thermal Evaporation
    • Vacuum Evaporation on Running Liquids (VERL)
• Figure 2 SCHEMATIC OF THE MODIFIED VERL PROCESS TO PRODUCE METAL NANOSUSPENSIONS
  • Thermal Plasma Synthesis
  • Combustion Synthesis
• Wet-Chemical Processes
  • Chemical Precipitation
  • Hydrothermal Processing
  • Sol-Gel Processing
• Figure 3 SOL-GEL SYNTHESIS FLOW CHART
  • Solid-State Processes
    • High-Energy Milling
    • Mechanochemical Synthesis
• TECHNOLOGIES FOR PRODUCING ORGANIC NANOPARTICLES
  • Lipids
  • Dendrimers
• PRODUCING STABLE DISPERSIONS
• PRODUCTION OF COATINGS, COMPONENTS, AND DEVICES
  • COATINGS
    • Slurry-Coating Routes
    • Dip Coating
    • Spin Coating
    • Comparison with Vapor-Deposition Techniques
• Table 4 COMPARISON OF COATING TECHNOLOGIES
  • Electrophoretic Deposition
  • Jet-Printing Process
  • Thermal Spray Coating
  • Direct Production of Nanostructured Coatings and Bulk Solids
  • Electrodeposition
  • Amorphous Crystallization
• COMPONENTS AND DEVICES
  • Consolidation of Nanoparticles into Components
    • Three-Dimensional Gel Lamination
    • Dynamic-Magnetic Consolidation
    • Field-Assisted Sintering Techniques
    • Quasi-Isostatic Pressure Process
    • Shockwave Compaction
    • Sinter Forging
    • Severe Plastic Deformation
• SELF-ASSEMBLY OF NANOPARTICLES
  • "BRICKS-AND-MORTAR"APPROACH ORDERS GOLD PARTICLES
  • MICELLES ENABLE ASSEMBLY OF NANOLAMINATES
  • VIRAL BIOTEMPLATE ORGANIZES NANOMETAL PARTICLES INTO ARRAYS
  • MAGNETIC NANOPARTICLE DISPERSIONS SELF-ASSEMBLE INTO ORDERED ARRAYS
• U.S. PATENT ANALYSIS
  • Introduction
  • Trends by Country
  • Trends by Assignee
• Figure 4 U.S. PATENT TRENDS BY ASSIGNEE' S COUNTRY (NUMBER OF PATENTS ISSUED BETWEEN 10/15/2005 AND 10/15/2007)
• Figure 5 SHARES OF U.S. PATENTS BY ASSIGNEE (%)
• Table 5 COMPANIES AND INSTITUTIONS AWARDED TWO OR MORE NANOMATERIAL-RELATED PATENTS BETWEEN OCTOBER 15, 2005 AND OCTOBER 15, 2007
  • Trends by Emphasis: Production versus Application
• Figure 6 SHARES OF PATENTS ISSUED BY EMPHASIS (%)
• Chapter 4 - INDUSTRY STRUCTURE
  • PRODUCERS
• Table 6 COMPANIES WORLDWIDE INVOLVED IN NANOPARTICLE DEVELOPMENT OR PRODUCTION FOR BIOMEDICAL AND COSMETIC APPLICATIONS
• Table 7 (CONTINUED)
• Figure 7 GEOGRAPHICAL DISTRIBUTION OF COMPANIES INVOLVED IN NANOPARTICLE DEVELOPMENT OR PRODUCTION FOR BIOMEDICAL AND COSMETIC APPLICATIONS (%)
  • COMMERCIAL PRODUCTS
  • NANOPARTICLE PRICING
• Table 7 FACTORS THAT IMPACT THE PRICING OF NANOPARTICLES
  • COMMERCIALIZATION STRATEGIES
  • INTERNATIONAL COMPETITION
  • REGULATORY ENVIRONMENT
  • REGULATION IN THE U.S.
    • U.S. Food and Drug Administration
      • Medical Devices
      • Drugs and Biologicals
      • Combination Products
    • U.S. Environmental Protection Agency
      • Other Agencies
  • REGULATION OVERSEAS
• GOVERNMENT FUNDING
  • NATIONAL NANOTECHNOLOGY INITIATIVE (NNI)
• Table 8 NNI BUDGET REQUESTS FOR NATIONAL INSTITUTES OF HEALTH, 2004-2008 ($ MILLIONS)
• Figure 8 RECENT TRENDS IN U.S. NATIONAL NANOTECHNOLOGY INITIATIVE SPENDING ON BIOMEDICAL R&D NANOTECHNOLOGY RESEARCH, FY 2004-2008 (BUDGET REQUESTS IN $ MILLIONS)
  • THE ADVANCED TECHNOLOGY PROGRAM (ATP)
    • Background
    • Relevant Awards
• Table 9 ADVANCED TECHNOLOGY PROGRAM AWARDS RELATED TO BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS OF NANOPARTICLES, 1999-2008 ($ MILLIONS)
  • SMALL BUSINESS INNOVATION RESEARCH (SBIR) AND SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAMS
  • Background
  • Relevant Awards
• Table 10 RECIPIENTS OF THREE OR MORE NANOMATERIALS-RELATED PHASE I SBIR/STTR AWARDS, 1991-2007 (NUMBERS ARE LOWER-BOUNDS)
• Chapter 5 - WORLD MARKETS
  • INTRODUCTION
  • WORLD MARKETS OVERVIEW
    • OVERALL MARKET FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS
• Figure 9 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL AND COSMETIC APPLICATIONS, 2006-2012 ($ MILLIONS)
• Figure 10 WORLD MARKET FORECAST FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS, 2006-2012 (MILLION KG)
  • MARKET SEGMENTATION BY APPLICATION
    • Segmentation in Terms of Value
• Table 11 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS BY TYPE OF APPLICATION IN TERMS OF VALUE, THROUGH 2012 ($ MILLIONS)
• Table 11 (CONTINUED)
• Figure 11WORLD NANOPARTICLES MARKET SHARE PROJECTIONS BY APPLICATION, 2006-2012 (%)
  • Segmentation in Terms of Volume
• Table 12 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS BY APPLICATION IN TERMS OF VOLUME, THROUGH 2012 (KG)
  • MARKET SEGMENTATION BY MATERIAL TYPE
    • Segmentation in Terms of Value
• Table 13 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS BY MATERIAL TYPE IN TERMS OF VALUE, THROUGH 2012 ($ MILLIONS)
• Figure 12WORLD MARKET SHARE PROJECTIONS FOR NANOPARTICLES BY MATERIAL TYPE, 2006-2012 (%)
  • Segmentation in Terms of Volume
• Table 14 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIOMEDICAL, PHARMACEUTICAL, AND COSMETIC APPLICATIONS BY MATERIAL TYPE IN TERMS OF VOLUME, THROUGH 2012 (KG)
  • DETAILED MARKET ANALYSIS
    • ANTIMICROBIAL MATERIALS
      • Background
      • Materials, Production, and Technical Requirements
      • Commercial and Regulatory Status
        • Antimicrobial Materials
• Table 15 ANTIMICROBIAL PRODUCTS INCORPORATING SILVER NANOPARTICLES
  • Nucryst Pharmaceuticals
  • Surfacine Development Co.
  • Try Co.
  • Fraunhofer Institute
  • Mineral Supplements
• World Markets
• Figure 13 PROJECTED TRENDS IN THE WORLD MARKET FOR NANOPARTICULATE SILVER USED IN ANTIMICROBIAL APPLICATIONS, 2006-2012 ($ MILLIONS)
  • Antimicrobial Dressings
• Table 16 WORLD MARKET PROJECTIONS FOR NANOPARTICULATE SILVER, THROUGH 2012 (KG/$ MILLIONS)
  • Dietary Supplements
• BIOLOGICAL DETECTION AND LABELING
  • Background
  • Materials, Production, and Technical Requirements
• Table 17 BASIC REQUIREMENTS OF DIAGNOSTIC TESTS
  • Commercial and Regulatory Status
    • Established Applications
      • Colloidal Gold
• Table 18 RAPID DIAGNOSTIC TESTS THAT USE GOLD NANOPARTICLES AS LABELS
  • Nanoprobes, Inc.
  • Orasure Technologies, Inc.
  • Dendrimers
  • Emerging Technologies and Applications
• Table 19 EMERGING NANOPARTICLE-BASED TECHNOLOGIES FOR BIODETECTION AND LABELING BY COMPANY
• Table 20 COMPARISON OF VARIOUS TYPES OF EMERGING NANOPARTICULATE LABELING TECHNOLOGIES
  • BioCrystal, Ltd.
  • Evident Technologies
  • MagnaBioSciences, LLC
  • Microcosm, Inc.
  • Nanocrystal Technologies, LP
  • Nanosphere, Inc.
  • NymoxPharmaceutical Corp.
  • Quantum Dot Corp.
• Table 21 COMPARISON BETWEEN QDOTS AND CONVENTIONAL ORGANIC DYES
  • World Markets
• Table 22 WORLD MARKET PROJECTIONS FOR NANOPARTICLES IN BIODETECTION AND LABELING APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
• Figure 14 PROJECTED TRENDS IN THE WORLD MARKET FOR NANOPARTICLES USED IN BIODETECTION AND LABELING APPLICATIONS, 2006-2012 ($ MILLIONS)
  • Colloidal Gold
• Table 23 WORLD MARKET PROJECTIONS FOR NANOPARTICULATE GOLD USED IN BIOLABELING APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
  • Dendrimers
• Table 24 WORLD MARKET PROJECTIONS FOR DENDRIMERS USED IN BIOLABELING APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
• Semiconductor Nanoparticles
• Table 25 WORLD MARKETPROJECTIONS FOR SEMICONDUCTOR NANOPARTICLES USED IN BIOLABELING APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
  • Superparamagnetic Particles
• Table 26 WORLD MARKET PROJECTIONS FOR SUPERPARAMAGNETIC NANOPARTICLES USED IN BIOLABELING APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
  • BIOMAGNETIC SEPARATIONS
    • Background
    • Materials, Production, and Technical Requirements
      • Commercial and Regulatory Status
• Table 27 PRODUCERS OF SUPERPARAMAGNETIC MICROSPHERES FOR BIOLOGICAL SEPARATION APPLICATIONS
  • World Markets
• Table 28 WORLD MARKETS FOR IRON OXIDE NANOPARTICLES IN BIOMAGNETIC SEPARATIONS, THROUGH 2012 (KG/$ MILLIONS)
• Figure 15 PROJECTED TRENDS IN THE WORLD MARKET FOR NANOPARTICULATE IRON OXIDE USED IN BIOSEPARATION APPLICATIONS, 2006-2012 ($ MILLIONS)
  • DRUG DELIVERY
    • Background
• Table 29 CRITERIA FOR A NANOPARTICULATE DRUG DELIVERY VEHICLE
  • Materials, Production, and Technical Requirements
  • Commercial and Regulatory Status
• Table 30 COMPANIES ACTIVE IN THE DEVELOPMENT OF NANOPARTICLES FOR DRUG-DELIVERY APPLICATIONS
  • Cytimmune Sciences
• Table 31 TIMELINE OF NEW DRUG DEVELOPMENT PROCESS
  • PowderMed, Ltd.
  • SkyePharma
  • Starpharma
  • World Markets
• Table 32 WORLD MARKET PROJECTIONS FOR DENDRIMER-BASED DRUG DELIVERY SYSTEMS, THROUGH 2012 (KG/$ MILLIONS)
  • MAGNETIC RESONANCE IMAGING (MRI) CONTRAST AGENTS
    • Background
• Table 33 TYPES OF CONTRAST AGENTS USED FOR MRI IMAGING
  • Materials, Production, and Technical Requirements
• Commercial and Regulatory Status
• Table 34 SUPERPARAMAGNETIC IRON OXIDE CONTRAST MEDIA: REGULATORY AND MARKETING STATUS
  • World Markets
• Table 35 WORLD MARKET PROJECTIONS FOR NANOPARTICULATE IRON OXIDE USED IN MRI CONTRAST MEDIA, THROUGH 2012 (KG/$ MILLIONS)
• Figure 16 PROJECTED TRENDS IN THE WORLD MARKET FOR NANOPARTICULATE IRON OXIDE USED IN MRI CONTRAST APPLICATIONS, 2006-2012 ($ MILLIONS)
  • TRANSFECTION REAGENTS
    • Background
    • Materials, Production, and Technical Requirements
    • Commercial and Regulatory Status
    • World Markets
• Table 36 WORLD MARKET PROJECTIONS FOR DENDRIMERS USED IN TRANSFECTON REAGENTS, THROUGH 2012
• Figure 17 PROJECTED TRENDS IN THE WORLD MARKET FOR DENDRIMERS USED IN TRANSFECTION REAGENTS, 2006-2012 ($ MILLIONS)
  • ANTIOXIDANTS
    • Background
    • Materials, Production, and Technical Requirements
    • Commercial and Regulatory Status
  • World Markets
• Table 37 WORLD MARKET PROJECTIONS FOR SILICA HYDRIDE NANOPARTICLES USED IN NUTRACEUTICALS, THROUGH 2012 (KG/$ MILLIONS)
• Figure 18 PROJECTED TRENDS IN THE WORLD MARKET FOR SILICA HYDRIDE NANOPARTICLES USED IN ANTIOXIDANT NUTRACEUTICAL, 2006-2012 ($ MILLIONS)
  • ORTHOPEDIC AND DENTAL APPLICATIONS
    • Background
  • Materials, Production, and Technical Requirements
  • Commercial and Regulatory Status
• Table 38 COMPANIES ACTIVE IN DEVELOPING NANOPARTICLE-BASED BIOACTIVE CERAMICS
  • World Markets
• Table 39WORLD MARKET PROJECTIONS FOR NANOPARTICLE-BASED SYNTHETIC BONE AND TOOTH ENAMELS, THROUGH 2012 (KG/$ MILLIONS)
• Figure 19 PROJECTED TRENDS IN THE WORLD MARKET FOR NANOPARTICULATE HYDROXYAPATITE, 2006-2012 ($ MILLIONS)
  • World Markets (Continued)
• SUNSCREENS AND UV-PROTECTIVE COSMETICS
  • Background
• Table 40 SUNSCREEN INORGANIC AND ORGANIC ACTIVE INGREDIENTS
  • Materials, Production, and Technical Requirements
• Table 41 TECHNICAL REQUIREMENTS FOR NANOPARTICLES IN UV-SHIELDING APPLICATIONS
  • Commercial and Regulatory Status
• Table 42 PRODUCERS OF TIO2 AND ZNO PARTICLES AND DISPERSIONS
  • Commercial and Regulatory Status (Continued)
• Table 43 SUNSCREEN AND DAILY-USE SKIN PROTECTION PRODUCTS CONTAINING NANOPARTICULATE TIO2 AND ZNO
  • Recent Developments
    • Process for Preparing Passivated TiO2 Nanoparticles
    • Titanium Dioxide Coated with Silicon Dioxide
    • Coated TiO2 Nanoparticles
  • World Markets
• Table 44 PROJECTED TRENDS IN WORLDWIDE SUNSCREEN SALES, THROUGH 2012 ($ BILLIONS)
• Figure 20 PROJECTED TRENDS IN THE WORLD MARKET FOR TIO2 AND ZNO NANOPARTICLES USED IN SUNCREENS AND OTHER SKIN CARE PRODUCTS, 2006-2012 ($ MILLIONS)
• Table 45 WORLD MARKET PROJECTIONS FOR TIO2 AND ZNO NANOPARTICLES IN SUNSCREEN APPLICATIONS, THROUGH 2012 (KG/$ MILLIONS)
• Chapter 6 - COMPANY PROFILES
  • ADVANCED NANOTECHNOLOGY, LTD.
  • AMAG PHARMACEUTICALS, INC.
  • ALTAIR NANOTECHNOLOGIES, INC.
  • ANGSTROM MEDICA, INC.
  • APHIOS CORP.
  • ARGONIDE CORP.
  • BANGS LABORATORIES, INC.
  • BASF AG
  • BERKELEY ADVANCED BIOMATERIALS, INC.
  • BIOPHAN TECHNOLOGIES, INC.
  • CAPSULUTION NANOSCIENCE AG
  • CYTIMMUNE SCIENCES, INC.
  • DENDRITECH, INC.
  • DENDRITIC NANOTECHNOLOGIES, INC.
  • DOW CHEMICAL CO.
  • DONG SEO, INC.
  • DYNAL BIOTECH ASA
  • ELEMENTIS SPECIALTIES
  • EMD CHEMICALS, INC.
  • EVIDENT TECHNOLOGIES
  • EVONIK DEGUSSA GMBH
  • FLAMEL TECHNOLOGIES S.A.
  • INFRAMAT CORP.
  • INVITROGEN CORP.
  • ISHIHARA SANGYO KAISHA, LTD.
  • KEMIRA SPECIALTY
  • MAGNABIOSCIENCES, LLC
  • MICROCOSM, INC.
  • MICROMOD PARTIKELTECHNOLOGIE GMBH
  • NANOCARRIER CORP., LTD.
  • NANOPHASE TECHNOLOGIES CORP.
  • NANOPROBES, INC.
  • NANOSPHERE, INC.
  • NOVAVAX, INC.
  • NUCRYST PHARMACEUTICALS
  • NYMOX PHARMACEUTICAL CORP.
  • ORASURE TECHNOLOGIES, INC.
  • ORTHOVITA, INC.
  • OSI PHARMACEUTICALS, INC.
  • PHARMASOL GMBH
  • POLYSCIENCES, INC.
  • POWDERMED, LTD.
  • QUANTUM DOT CORP.
  • QIAGEN N.V.
  • RBC LIFE SCIENCES, INC.
  • SACHTLEBEN CHEMIE GMBH
  • SHOWA DENKO K.K.
  • SKYEPHARMA, PLC
  • SOMALOGIC, INC.
  • STARPHARMA HOLDINGS, LTD.
  • SURFACINE DEVELOPMENT CO.
  • TAYCA CORP.