Proteomics: An Assessment of the Technologies and Commercial Potential
Proteomics is an emerging field that has developed in the wake of genomics. Its goal is to understand protein expression at the
cellular level, and apply this information to scientific and medical problems. For example, compared to healthy cells, how does
influenza virus infection affect the total protein output? Are any of the proteins expressed only in the infected cells suitable
targets for new antiviral drugs? This approach also applies to cancerous cells, and cells from patients with degenerative
diseases and many other conditions. New technologies like protein chips and capillary electrophoresis are emerging to serve
proteomic studies, and more mature technologies like 2-D electrophoresis, mass spectroscopy, and nuclear magnetic
resonance spectroscopy are being adapted for protein studies, and in some cases, for high throughput uses. Bioinformatics
applications are constantly being developed to analyze the data produced by all of these technologies. This BCC study
examines how proteomics technologies have affected basic research and pharmaceutical research, and how they are likely to
affect research in the near future. It also analyzes how proteomics technologies are developing, and examines new companies
that are likely to make substantial contributions to the field. An important part of the report analyzes instruments that are vital to
proteomics studies. Sales and spending projections through 2006 are included.
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