Abstract
RNA interference (RNAi) has rapidly evolved into a powerful technique to
silence gene expression in cells allowing researchers to study the molecular
effects of modulating expression at the level of individual genes. The
diversity of its applications has made RNAi an indispensable tool for both
academic and industrial scientists interested in gene function
characterization, signaling pathway analysis, and target validation.
From the perspective of industrial scientists who use synthetic siRNA, this
report will:
- Identify the RNAi research objectives of pharmaceutical and biotech
scientists;
- Present siRNA customer purchasing preferences by key experimental design
parameters;
- Examine future research trends in nucleic acid-based gene silencing;
- Determine industrial throughput levels of synthetic siRNAs per target gene;
- Assess market growth potential for custom, pre-designed, and validated
synthetic siRNAs;
- Reveal preferred suppliers of synthetic siRNAs and their Net Promoter
Score rankings;
- Determine synthetic siRNA brand share by usage rates and relative
expenditure for the U.S. market and the rest of the world market;
- Understand the role of customer satisfaction and brand loyalty in the
purchasing decision;
- Provide insights into which product attributes contribute to customer
satisfaction and customer dissatisfaction; and
- Evaluate brand health of the top suppliers based upon key performance
metrics related to product promotion, product attractiveness, product price,
product placement and supplier customer service and technical support.