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[Report]

The Drug Target Atlas of Apoptopic Drugs in Oncology

Published: 2008/02

Contact 24 hrs/day
Description

Table of Contents

  • 1. Executive Summary
  • 2. About Cancer Highlights
  • 3. Methodologies
  • 4. Table of Contents
    • 4.1 List of Figures
    • 4.2 List of Tables
  • 5. Introduction
  • 6. Apoptopic Drug Compound Types and Sub-cellular Localizations of Targets
  • 7. The Cancer Genome Project and Apoptopic Drug Targets
    • 7.1 Apoptopic Drug Targets Present in the Cancer Gene Census and in the Catalogue of Somatic Mutations in Cancer
  • 8. Protein Expression Profiles of Apoptopic Drug Targets in Human
    • 8.1 Expression in Normal Tissues and Cancer Tissues
    • 8.2 Expression in Human Cancer Cell Lines and Primary Cells
  • 9. Pathway Analysis of Drug Targets of Apoptopic Drugs
  • 10. Protein-Protein Interactions Between Identified Apoptopic Drug Targets
  • 11. Available Biological Structure Data on Apoptopic Drug Targets
  • 12. Drug Target Profiles of Apoptopic Drug Targets in Oncology
    • 12.1.1 Auxiliary transport protein activity
    • 12.1.2 Carboxy-lyase activity
    • 12.1.3 Catalytic activity
    • 12.1.4 Cell adhesion molecule activity
    • 12.1.5 Chaperone activity
    • 12.1.6 Complement activity
    • 12.1.7 Cysteine-type peptidase activity
    • 12.1.8 Cytokine activity
    • 12.1.9 DNA topoisomerase activity
    • 12.1.10 Glutathione transferase activity
    • 12.1.11 Hormone activity
    • 12.1.12 Hydrolase activity
    • 12.1.13 Intracellular ligand-gated ion channel activity
    • 12.1.14 Kinase activity
    • 12.1.15 Kinase regulator activity
    • 12.1.16 Ligase activity
    • 12.1.17 Lipid kinase activity
    • 12.1.18 Metallopeptidase activity
    • 12.1.19 Molecular function unknown
    • 12.1.20 Motor activity
    • 12.1.21 Oxidoreductase activity
    • 12.1.22 Peptide hormone
    • 12.1.23 Peroxidase activity
    • 12.1.24 Protein binding
    • 12.1.25 Protein serine/threonine kinase activity
    • 12.1.26 Protein threonine/tyrosine kinase activity
    • 12.1.27 Protein-tyrosine kinase activity
    • 12.1.28 Receptor activity
    • 12.1.29 Receptor binding
    • 12.1.30 Receptor signaling complex scaffold activity
    • 12.1.31 Receptor signaling protein serine/threonine kinase activity
    • 12.1.32 RNA binding
    • 12.1.33 Structural constituent of cytoskeleton
    • 12.1.34 Superoxide dismutase activity
    • 12.1.35 T cell receptor activity
    • 12.1.36 Transcription factor activity
    • 12.1.37 Transcription regulator activity
    • 12.1.38 Transferase activity
    • 12.1.39 Translation regulator activity
    • 12.1.40 Transmembrane receptor activity
    • 12.1.41 Transmembrane receptor protein tyrosine kinase activity
    • 12.1.42 Transporter activity
  • 13. Apoptopic Drug Target Mix by Development Stage
  • 14. Apoptopic Drug Target Mix by Cancer Indication
    • 14.1 Basal Cell Cancer
    • 14.2 Biliary Cancer
    • 14.3 Bladder Cancer
    • 14.4 Bone Cancer
    • 14.5 Brain Cancer
    • 14.6 Breast Cancer
    • 14.7 Carcinoid Tumor
    • 14.8 Cervical Cancer
    • 14.9 Chemotherapy-induced Neutropenia
    • 14.10 Colorectal Cancer
    • 14.11 Endometrial Cancer
    • 14.12 Fallopian Tube Cancer
    • 14.13 Gastrointestinal Cancer
      • 14.13.1 Gastrointestinal Stomach Cancer
      • 14.13.2 Gastrointestinal Stromal Cancer
    • 14.14 Head and Neck Cancer
    • 14.15 Leukemia
      • 14.15.1 Acute Lymphocytic Leukemia
      • 14.15.2 Acute Myelogenous Leukemia
      • 14.15.3 Chronic Lymphocytic Leukemia
      • 14.15.4 Chronic Myelogenous Leukemia
    • 14.16 Liver Cancer
    • 14.17 Lung Cancer
      • 14.17.1 Non-Small Cell Lung Cancer
      • 14.17.2 Small Cell Lung Cancer
    • 14.18 Lymphoma
      • 14.18.1 B-cell Lymphoma
      • 14.18.2 Hodgkin' s Lymphoma
      • 14.18.3 non-Hodgkin' s Lymphoma
      • 14.18.4 T-cell Lymphoma
    • 14.19 Melanoma
    • 14.20 Mesothelioma
    • 14.21 Myelodysplastic Syndrome
    • 14.22 Myeloma
    • 14.23 Nasopharyngeal Cancer
    • 14.24 Oesophageal Cancer
    • 14.25 Oral Cancer
    • 14.26 Ovarian Cancer
    • 14.27 Pancreatic Cancer
    • 14.28 Peritoneal Cancer
    • 14.29 Prostate Cancer
    • 14.30 Renal Cancer
    • 14.31 Sarcoma
      • 14.31.1 Leiomyo Sarcoma
    • 14.32 Squamous Cell Cancer
    • 14.33 Testicular Cancer
    • 14.34 Thymoma Cancer
    • 14.35 Thyroid Cancer
  • 15. Apoptopic Drugs and their Targets by Companies
    • 15.1 Australia
    • 15.2 Canada
    • 15.3 China
    • 15.4 Denmark
    • 15.5 Germany
    • 15.6 Israel
    • 15.7 Japan
    • 15.8 South Korea
    • 15.9 Spain
    • 15.10 Switzerland
    • 15.11 Taiwan
    • 15.12 United Kingdom
    • 15.13 USA
  • 16. Disclaimer
  • 17. Drug Index
  • 18. Company Index

4.1 List of Figures

  • Figure 1: Distribution of Compound Types Among Apoptopic Drugs
  • Figure 2: Primary Sub-cellular Localization of Drug Targets

4.2 List of Tables

  • Table 1: Compound Type Versus Primary and Alternate Localization of Drug Target
  • Table 2: Drug Targets of Apoptopic Drugs Present in the Catalogue of Somatic Mutations in Cancer and in the Cancer Gene Census
  • Table 3: Available Protein Expression Profiles of Apoptopic Drug Targets
  • Table 4: Pathway Summary
  • Table 5: Drug Targets Without any Identified Assigned Pathways
  • Table 6: Pathway Profile According to BioCarta of the Drug Targets Belonging to Apoptopic Drugs
  • Table 7: Drug Targets Belonging to Apoptopic Pathways According to BioCarta
  • Table 8: Pathway Profile According to KEGG of the Drug Targets Belonging to Apoptopic Drugs
  • Table 9: Drug Targets within the Apoptosis Pathway According to KEGG
  • Table 10: Apoptopic Drugs Targeting Major Singaling Pathways
  • Table 11: Protein-Protein Interactions Between Identified Apoptopic Drug Targets
  • Table 12: Targets of Apoptopic Drugs without Protein-Protein Interaction with other Drug Targets
  • Table 13: Number of Available Biological Structures on Apoptopic Drug Targets
  • Table 14: Overview of Drug Target Profile Themes
  • Table 15: Fall Out in Terms of the Number of Drug Target Mixes, Drugs, and Developmental Projects by Developmental Stage
  • Table 16: Apoptopic Drug Target Mixes by Development
  • Table 17: Number of Unique Apoptopic Drug Target Mixes Reported by Cancer Indication
  • Table 18: Apoptopic Drug Target Mix for the Treatment of Basal Cell Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 19: Apoptopic Drug Target Mix for the Treatment of Biliary Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 20: Apoptopic Drug Target Mix for the Treatment of Bladder Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 21: Apoptopic Drug Target Mix for the Treatment of Bone Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 22: Apoptopic Drug Target Mix for the Treatment of Brain Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 23: Apoptopic Drug Target Mix for the Treatment of Breast Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 24: Apoptopic Drug Target Mix for the Treatment of Carcinoid Tumor According to the Compound Type and Developmental Stage of Drug
  • Table 25: Apoptopic Drug Target Mix for the Treatment of Cervical Cancer According to the Compound Type Developmental Stage of Drug
  • Table 26: Apoptopic Drug Target Mix for the Treatment of Chemotherapy-induced Neutropenia According to Compound Type and Developmental Stage of Drug
  • Table 27: Apoptopic Drug Target Mix for the Treatment of Colorectal Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 28: Apoptopic Drug Target Mix for the Treatment of Endometrial Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 29: Apoptopic Drug Target Mix for the Treatment of Fallopian Tube Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 30: Apoptopic Drug Target Mix for the Treatment of Gastrointestinal Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 31: Apoptopic Drug Target Mix for the Treatment of Gastrointestinal Stomach Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 32: Apoptopic Drug Target Mix for the Treatment of Gastrointestinal Stromal Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 33: Apoptopic Drug Target Mix for the Treatment of Head and Neck Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 34: Apoptopic Drug Target Mix for the Treatment of Leukemia (general) According to the Compound Type and Developmental Stage of Drug
  • Table 35: Apoptopic Drug Target Mix for the Treatment of Acute Lymphocytic Leukemia According to the Compound Type and Developmental Stage of Drug
  • Table 36: Apoptopic Drug Target Mix for the Treatment of Acute Myelogenous Leukemia According to the Compound Type and Developmental Stage of Drug
  • Table 37: Apoptopic Drug Target Mix for the Treatment of Chronic Lymphocytic Leukemia According to the Compound Type and Developmental Stage of Drug
  • Table 38: Apoptopic Drug Target Mix for the Treatment of Chronic Myelogenous Leukemia According to the Compound Type and Developmental Stage of Drug
  • Table 39: Apoptopic Drug Target Mix for the Treatment of Liver Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 40: Apoptopic Drug Target Mix for the Treatment of Lung Cancer (general) According to the Compound Type and Developmental Stage of Drug
  • Table 41: Apoptopic Drug Target Mix for the Treatment of Non-Small Cell Lung Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 42: Apoptopic Drug Target Mix for the Treatment of Small Cell Lung Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 43: Apoptopic Drug Target Mix for the Treatment of Lymphoma (general) According to the Compound Type and Developmental Stage of Drug
  • Table 44: Apoptopic Drug Target Mix for the Treatment of B-cell Lymphoma According to the Compound Type and Developmental Stage of Drug
  • Table 45: Apoptopic Drug Target Mix for the Treatment of Hodgkin' s Lymphoma According to the Compound Type and Developmental Stage of Drug
  • Table 46: Apoptopic Drug Target Mix for the Treatment of non-Hodgkin' s Lymphoma According to the Compound Type and Developmental Stage of Drug
  • Table 47: Apoptopic Drug Target Mix for the Treatment of T-cell Lymphoma According to the Compound Type and Developmental Stage of Drug
  • Table 48: Apoptopic Drug Target Mix for the Treatment of Melanoma According to the Compound Type and Developmental Stage of Drug
  • Table 49: Apoptopic Drug Target Mix for the Treatment of Mesothelioma According to the Compound Type and Developmental Stage of Drug
  • Table 50: Apoptopic Drug Target Mix for the Treatment of Myelodysplastic Syndrome According to the Compound Type and Developmental Stage of Drug
  • Table 51: Apoptopic Drug Target Mix for the Treatment of Myeloma According to the Compound Type and Developmental Stage of Drug
  • Table 52: Apoptopic Drug Target Mix for the Treatment of Nasopharyngeal Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 53: Apoptopic Drug Target Mix for the Treatment of Oesophageal Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 54: Apoptopic Drug Target Mix for the Treatment of Oral Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 55: Apoptopic Drug Target Mix for the Treatment of Ovarian Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 56: Apoptopic Drug Target Mix for the Treatment of Pancreatic Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 57: Apoptopic Drug Target Mix for the Treatment of Peritoneal Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 58: Apoptopic Drug Target Mix for the Treatment of Prostate Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 59: Apoptopic Drug Target Mix for the Treatment of Renal Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 60: Apoptopic Drug Target Mix for the Treatment of Sarcoma (general) According to the Compound Type and Developmental Stage of Drug
  • Table 61: Apoptopic Drug Target Mix for the Treatment of Leiomyo Sarcoma According to the Compound Type and Developmental Stage of Drug
  • Table 62: Apoptopic Drug Target Mix for the Treatment of Squamous Cell Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 63: Apoptopic Drug Target Mix for the Treatment of Testiculat Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 64: Apoptopic Drug Target Mix for the Treatment of Thymoma Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 65: Apoptopic Drug Target Mix for the Treatment of Thyroid Cancer According to the Compound Type and Developmental Stage of Drug
  • Table 66: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in Australia
  • Table 67: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in Canada
  • Table 68: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in China
  • Table 69: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in Denmark
  • Table 70: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in Germany
  • Table 71: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in Israel
  • Table 72: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in Japan
  • Table 73: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in South Korea
  • Table 74: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in Spain
  • Table 75: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in Switzerland
  • Table 76: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in Taiwan
  • Table 77: Apoptopic Drugs with Target Mix and Developmental Projects by Companies in United Kingdom
  • Table 78: Apoptopic Drugs with Target Mix and Developmental Projects by Company in USA
Description

[Report]
The Drug Target Atlas of Apoptopic Drugs in Oncology
Published: 2008/02
Published by : BioSeeker Group AB BioSeeker Group AB

Price:
US $ 3,675.00 PDF by E-mail (Single User License)
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Product Code : BG62356
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