Abstract
Proteomics is a rapidly evolving field that is rife with commercial
opportunities as the technology achieves ever higher throughput at lower cost
and greater sensitivity. Proteomics: Current State and Future Directions is a
new CHA Advances report that delivers an up-to-the-minute assessment of the
state of proteomics and its applications in drug and biomarker discovery. The
report provides insight into:
- Strengths and weaknesses of the leading technologies for protein
separation, detection, and quantification - with an emphasis on
high-throughput approaches
- The fundamental challenge posed by the vast dynamic range among protein
concentrations, and the potential solutions in development and entering the
market
- Recent applications of proteomics to discover biomarkers for preeclampsia,
and for neonatal ureteropelvic junction, and to differentiate between
diagnosis of ALS and Parkinson' s disease
- Technologies such as mass spectrometry, antibody-bearing chips, and
solution array multiplexing to address the challenge of detecting
low-abundance proteins
- The most significant research initiatives and recent product
introductions, company profiles, and the major deals and M&As that are shaping
the proteomics landscape
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