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[Report]

Commercial Insight: Antidiabetics - Billion Dollar Drugs, Pipeline Dreams?

Published: 2005/07

Contact 24 hrs/day
Description

ABOUT DATAMONITOR HEALTHCARE

About the Cardiovascular pharmaceutical analysis team

CHAPTER 1 EXECUTIVE SUMMARY

Objective of the analysis
Datamonitor insight into the antidiabetics market

CHAPTER 2 MARKET DEFINITION AND OVERVIEW

Market definition for this report
Current market situation
National markets
The insulin market
Humalog
NovoLin
Lantus
Humulin
NovoRapid/NovoLog
Outlook
Thiazolidinediones
Actos
Avandia
Sulfonylureas
Amaryl
Glucotrol XL
Biguanides
Glucophage
Strategic scoping and focus

CHAPTER 3 COUNTRY MARKET ASSESSMENTS

Current and future opportunities and threats in the antidiabetics market
Global opportunities and threats
Opportunities
Threats
US: current market assessment
Overview
US market issues
Japan: current market assessment
Overview
Japan market issues
Europe: current market assessment
Overview
Europe market issues
Summary of environmental issues affecting the antidiabetic market size

CHAPTER 4 FORECAST ANALYSIS

Assumptions and events

Ongoing trends
Increasing market size
Trial results
PROACTIVE
CHICAGO and PERISCOPE
DREAM
ACCORD
ADOPT
ORIGIN
NAVIGATOR
New product launches
Byetta and Exenatide LAR
Symlin
Pargluva
Vildagliptin
Liraglutide
Exubera
AERx iDMS
Patent expiries
Limitations of data
Forecasts

CHAPTER 5 COMMERCIAL IMPACT AND LIFECYCLE MANAGEMENT: CASE STUDIES

Introduction
Case study 1
Aventis: Building a successful insulin portfolio
Competitive landscape
Lantus
Lantus strategic analysis
Conclusion
Apidra
Exubera
The basis of commercial success
Case study 2
BMS: Managing the lifecycle of Glucophage
Patent protection strategies
DepoMed announces lawsuit against BMS for Glucophage XR patent infringement
Study published in JAMA reveals Glucophage is prescribed to patients with heart and kidney disorders, despite black box warning of lactic acidosis side-effect
Merck Sante announces a trademark and patent-licensing agreement with Sumitomo Pharmaceuticals for the development and commercialization of Glucophage and Glucophage XR in Japan
BMS announces FDA approval of 750mg dose of Glucophage XR
Strategic analysis

APPENDIX A - MAJOR BRAND KEY FACTS

Insulin market data
Humulin
Humalog
NovoLin
NovoRapid/NovoLog
Lantus
TZDs market data
Actos
Avandia
Sulfonylureas market data
Amaryl
Glucotrol XL
Biguanide market data
Glucophage and Glucophage XR

APPENDIX B

Bibliography
Epidemiology
Clinical trial data
Report methodology
Standard units
Japanese market data
About Datamonitor
About Datamonitor Healthcare
About the Cardiovascular Disease analysis team
Disclaimer

List of Tables

Table 1: Global sales in the antidiabetic market by drug class, 2004
Table 2: Global sales of the leading branded insulin families, 2003-04
Table 3: Global sales of the leading branded TZDs, 2003-04
Table 4: Global sales of the leading branded sulfonylureas, 2003-04
Table 5: Global sales of the leading branded biguanide compared to generics, 2003-04
Table 6: Future prevalence of type 1 and type 2 diabetes in the seven major markets, 2004-12
Table 7: Prevalence of obesity in the seven major markets by age (000s), 2003
Table 8: US sales and growth of drug classes
Table 9: Japan sales and growth of drug classes
Table 10: EU5 sales and growth of drug classes
Table 11: Patent expiry dates used in forecasting antidiabetics market
Table 12: Key Lantus events
Table 13: Key Glucophage and Glucophage XR events
Table 14: Annual cost of therapy for Glucophage brands versus generics
Table 15: Humulin: key facts
Table 16: Humalog: key facts
Table 17: NovoLin: key facts
Table 18: NovoLog: key facts
Table 19: Lantus: key facts
Table 20: Actos: key facts
Table 21: Avandia: key facts
Table 22: Amaryl: key facts
Table 23: Glucotrol XL: key facts
Table 24: Glucophage and Glucophage XR: key facts

List of Figures

Figure 1: Sales and growth for antidiabetic drug classes in the seven major markets, 2003-04
Figure 2: Share of antidiabetics market represented by each of the seven major markets in 2004
Figure 3: Pioglitazones effects on triglyceride and HDL cholesterol levels
Figure 4: Proportion of population 20-39 years of age, 2003 and 2015 and prevalence of diabetes in this age group, 2003
Figure 5: Proportion of population 40-59 years of age, 2003 and 2015 and prevalence of diabetes in this age group, 2003
Figure 6: Proportion of population 60-79 years of age, 2003 and 2015 and prevalence of diabetes in this age group, 2003
Figure 7: Annual US sales of the antidiabetic drug classes, 2001-04
Figure 8: Annual Japan sales of the antidiabetic drug classes, 2001-04
Figure 9: Annual EU5 sales of the antidiabetic drug classes, 2001-04
Figure 10: Summary of environmental issues
Figure 11: SWOT analysis for Lantus
Figure 12: SWOT analysis for the Glucophage franchise
Description

[Report]
Commercial Insight: Antidiabetics - Billion Dollar Drugs, Pipeline Dreams?
Published: 2005/07
Published by : Datamonitor Datamonitor

Price:
US $ 15,200.00 PDF by E-mail (Single User License)
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Product Code : DC31842
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