Abstract
Overview
Introduction
Osteoarthritis (OA) is characterized by the progressive destruction of
articular joints and is a major cause of pain in Western populations. OA is
the most common form of arthritis and severely impacts on the physical
function and day-to-day quality of life of an individual. OA also impacts
heavily on the economy and it is believed to cost the US an estimated $60
billion per year.
Scope
- Detailed pipeline analysis of the key products in development for OA, plus
indication specific drug sales forecasts to 2015
- Late-phase pipeline drug competitive analysis based on clinical and
commercial attractiveness
- Overview of patient potential and unmet needs in OA across the US, 5EU and
Japanese markets
- Identification of licensing opportunities based on company portfolio and
market needs
Report Highlights
The issue of cardiovascular safety remains at the forefront of the COX-2 and
traditional NSAID classes. As evidenced by Prexige (lumiracoxib) and Arcoxia
(etoricoxib), appropriately designed, large-scale safety studies will be
crucial if any COX-2s are to be approved by the FDA and EMEA. Prexige and
Arcoxia remain in pre-registration in the US.
Over the next ten years a number of COX-2 inhibitors as well as NSAIDs and
corticosteroids, some with novel mechanisms of action and reportedly improved
side effect profiles, will enter the market. Success will depend on effective
but restrained marketing, product differentiation and strategic out-licensing
arrangements.
Over the next ten years a number of COX-2 inhibitors as well as NSAIDs and
corticosteroids, some with novel mechanisms of action and reportedly improved
side effect profiles, will enter the market. Success will depend on effective
but restrained marketing, product differentiation and strategic out-licensing
arrangements.
Reasons to Purchase
- Understand the potential of COX-2s such as Novartis' Prexige and Merck's
Arcoxia in the OA indication.
- Quantify the future size and potential of the market for novel treatments
in the OA indication.
- Identify who the key players in the OA market will be as well as
understanding gaps in the market for potential products.
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